Претраживање
Приказ резултата 611-620 од 647
Consequences of MnSOD interactions with nitric oxide: Nitric oxide dismutation and the generation of peroxynitrite and hydrogen peroxide
(USA :Taylor & Francis INC, 2007)
The present study demonstrates that manganese superoxide dismutase (MnSOD) Escherichia coli, binds nitric oxide (NO) and stimulates its decay under both anaerobic and aerobic conditions. The results indicate that previously ...
Theoretical insight into sulfur aromatic interactions with extension to D-2 receptor activation mechanism
(Springer/Plenum Publishers, New York, 2015)
Contacts between aromatic rings and sulfur-containing amino acids are frequent in proteins. However, little is known about the nature of their interactions particularly if substituents are present on aromatic ring. In this ...
Cytotoxic Effect of Wine Polyphenolic Extracts and Resveratrol Against Human Carcinoma Cells and Normal Peripheral Blood Mononuclear Cells
(Mary Ann Liebert Inc, New Rochelle, 2010)
Red and white wine polyphenols have been reported to provide substantial health benefits. In this study, the cytotoxic activity of red and white wine polyphenolic extracts and of resveratrol was evaluated against different ...
Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities
(Elsevier, 2007)
The antiproliferative activity of previously synthesized (Z)-cholest-4-en-6-one oxime (1), (E)-cholest-4-en-6-one oxime (2), 7-aza-B-homocholest-4-en-6-one (3) and 6-aza-B-homocholest-4-en-7-one (4) and newly synthesized ...
Estrone derived steroidal diepoxide: Biologically active compound and precursor of a stable steroidal A,B-spiro system
(Elsevier Science Inc, New York, 2009)
A simple approach to a stable steroidal estrone derived A,B-spiro system is reported. Treatment of estrone derived A-ring diepoxyalcohol with the Ac2O-TMSOTf system at the ambient temperature led to acetylation, while at ...
Mixed steroidal tetraoxanes induce apoptotic cell death in tumor cells
(Investigational New Drugs, 2009)
In this study we investigated the antiproliferative activity of six mixed steroidal tetraoxanes against various tumor cell lines, the toxicity against normal peripheral blood mononuclear cells (PBMC), and the mode of HeLa ...
Diagnostic spectroscopic and computer-aided evaluation of malignancy from UV/VIS spectra of clear pleural effusions
(Elsevier, 2014)
The automated, computer-aided method for differentiation and classification of malignant (M) from benign (B) cases, by analyzing the UV/VIS spectra of pleural effusions is described. It was shown that by two independent ...
The electrocatalytic properties of the oxides of noble metals in the electrooxidation of methanol and formic acid
(Elsevier, 2001)
The electrooxidation of 0.25 M methanol as well as of 0.25 M formic acid was examined on oxides formed on the Au(111) electrode surface in 0.5 M H2SO4 and 0.5 M NaHCO3 at a sweep rate of 0.5 mV/s. In the case of methanol, ...
Electrochemical Oxidation of Donepezil and Its Voltammetric Determination at Gold Electrode
(Wiley-Blackwell, Malden, 2014)
The oxidative ability of donepezil, a frequently prescribed drug for the treatment of Alzheimer's disease is reported for the first time at a gold electrode. It was oxidized by cyclic voltammetry and determined by square ...
New androst-4-en-17-spiro-1,3,2-oxathiaphospholanes. Synthesis, assignment of absolute configuration and in vitro cytotoxic and antimicrobial activities
(Elsevier Science Inc, New York, 2012)
The reactions of 17 alpha-hydroxyprogesterone with Lawesson's reagent (LR) in toluene, CH2Cl2 and/or CCl4 gave, depending on the duration of the reaction, two diastereoisomeric androst-4-en-17-spiro-1,3,2-oxathiaphosphol ...