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Strain wars 3: Differences in infectivity and pathogenicity between Delta and Omicron strains of SARS-CoV-2 can be explained by thermodynamic and kinetic parameters of binding and growth
(Elsevier, 2022)
In this paper, for the first time, empirical formulas have been reported of the Delta and Omicron strains of SARS-CoV-2. The empirical formula of the Delta strain entire virion was found to be CH1.6383O0.2844N0.2294P0.0064S0.0042, ...
Beyond COVID-19: Do biothermodynamic properties allow predicting the future evolution of SARS-CoV-2 variants?
(Elsevier, 2022)
During the COVID-19 pandemic, many statistical and epidemiological studies have been published, trying to predict the future development of the SARS-CoV-2 pandemic. However, it would be beneficial to have a specific, ...
Strain Wars: Competitive interactions between SARS-CoV-2 strains are explained by Gibbs energy of antigen-receptor binding
(Elsevier, 2022)
Since the beginning of the COVID-19 pandemic, SARS-CoV-2 has mutated several times into new strains, with an increased infectivity. Infectivity of SARS-CoV-2 strains depends on binding affinity of the virus to its host ...
Why doesn’t Ebola virus cause pandemics like SARS-CoV-2?
(Elsevier, 2022)
Ebola virus is among the most dangerous, contagious and deadly etiological causes of viral diseases. However, Ebola virus has never extensively spread in human population and never have led to a pandemic. Why? The mechanistic ...
Closer look into HIV-host interactions: Standard Gibbs energy of binding of the gp120 antigen of HIV-1 to the CD4 receptor and monoclonal antibodies
(Bektas Tepe Publications, 2023)
HIV-1, like other viruses, represents an open thermodynamic system. This is why it is important to know its thermodynamic properties. Virus-host interactions are performed at the membrane as antigen-receptor binding. ...
Omicron BA.2.75 subvariant of SARS-CoV-2 is expected to have the greatest infectivity compared with the competing BA.2 and BA.5, due to most negative Gibbs energy of binding.
(MDPI, 2022)
Omicron BA.2.75 may become the next globally dominant strain of COVID-19 in 2022. The BA.2.75 sub-variant has acquired more mutations (9) in spike protein and other genes of SARS-CoV-2 than any other variant. Thus, its ...