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Omicron BA.2.75 subvariant of SARS-CoV-2 is expected to have the greatest infectivity compared with the competing BA.2 and BA.5, due to most negative Gibbs energy of binding.
Omicron BA.2.75 may become the next globally dominant strain of COVID-19 in 2022. The BA.2.75 sub-variant has acquired more mutations (9) in spike protein and other genes of SARS-CoV-2 than any other variant. Thus, its chemical composition and thermodynamic properties have changed compared with earlier variants. In this paper, the Gibbs energy of the binding and antigen-receptor binding rate was reported for the BA.2.75 variant. Gibbs energy of the binding of the Omicron BA.2.75 variant is more negative than that of the competing variants BA.2 and BA.5.
Keywords:
BA.2.75 variant / Gibbs energy of binding / binding rate / infectivity / SARS-CoV-2 / phenomenological equation / nonequilibrium thermodynamics / chemical kinetics / Omicron
TY - JOUR
AU - Popović, Marko
PY - 2022
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/6111
AB - Omicron BA.2.75 may become the next globally dominant strain of COVID-19 in 2022. The BA.2.75 sub-variant has acquired more mutations (9) in spike protein and other genes of SARS-CoV-2 than any other variant. Thus, its chemical composition and thermodynamic properties have changed compared with earlier variants. In this paper, the Gibbs energy of the binding and antigen-receptor binding rate was reported for the BA.2.75 variant. Gibbs energy of the binding of the Omicron BA.2.75 variant is more negative than that of the competing variants BA.2 and BA.5.
PB - MDPI
T2 - BioTech
T1 - Omicron BA.2.75 subvariant of SARS-CoV-2 is expected to have the greatest infectivity compared with the competing BA.2 and BA.5, due to most negative Gibbs energy of binding.
VL - 11
IS - 4
SP - 45
DO - 10.3390/biotech11040045
ER -
@article{
author = "Popović, Marko",
year = "2022",
abstract = "Omicron BA.2.75 may become the next globally dominant strain of COVID-19 in 2022. The BA.2.75 sub-variant has acquired more mutations (9) in spike protein and other genes of SARS-CoV-2 than any other variant. Thus, its chemical composition and thermodynamic properties have changed compared with earlier variants. In this paper, the Gibbs energy of the binding and antigen-receptor binding rate was reported for the BA.2.75 variant. Gibbs energy of the binding of the Omicron BA.2.75 variant is more negative than that of the competing variants BA.2 and BA.5.",
publisher = "MDPI",
journal = "BioTech",
title = "Omicron BA.2.75 subvariant of SARS-CoV-2 is expected to have the greatest infectivity compared with the competing BA.2 and BA.5, due to most negative Gibbs energy of binding.",
volume = "11",
number = "4",
pages = "45",
doi = "10.3390/biotech11040045"
}
Popović, M.. (2022). Omicron BA.2.75 subvariant of SARS-CoV-2 is expected to have the greatest infectivity compared with the competing BA.2 and BA.5, due to most negative Gibbs energy of binding.. in BioTech
MDPI., 11(4), 45.
https://doi.org/10.3390/biotech11040045
Popović M. Omicron BA.2.75 subvariant of SARS-CoV-2 is expected to have the greatest infectivity compared with the competing BA.2 and BA.5, due to most negative Gibbs energy of binding.. in BioTech. 2022;11(4):45.
doi:10.3390/biotech11040045 .
Popović, Marko, "Omicron BA.2.75 subvariant of SARS-CoV-2 is expected to have the greatest infectivity compared with the competing BA.2 and BA.5, due to most negative Gibbs energy of binding." in BioTech, 11, no. 4 (2022):45,
https://doi.org/10.3390/biotech11040045 . .
