Претраживање
Приказ резултата 1-10 од 89
Nanocrystal dispersion of DK-I-56–1, a poorly soluble pyrazoloquinolinone positive modulator of α6 GABAA receptors: Formulation approach toward improved in vivo performance
(Elsevier, 2020)
DK-I-56–1 (7‑methoxy‑2-(4‑methoxy‑d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one), a recently developed deuterated pyrazoloquinolinone, has been recognized as a lead candidate for treatment of various neuropsychiatric ...
Varietal differences of Prokupac, Evita and Čokot Zemun based on their anthocyanins content in grape skin extract
(Chemistry & Biodiversity, 2021)
In this study we have analyzed the anthocyanin composition of skin extracts of three red grape varieties Prokupac, Evita and Čokot Zemun in order to distinguish these cultivars based on their anthocyanin profile. Also, ...
Novel derivatives of aroylacrylic acid phenylamides as inducers of apoptosis through the ROS-mediated pathway in several cancer cell lines
(Elsevier, 2022)
In the present work, the α, β-double bond of the aroylacrylic acid phenylamides was suitably modified to optimize the toxicity–antiproliferative activity ratio of the resulting compounds 1 –5 . The phenylamides were modified ...
Functional ibuprofen-loaded cationic nanoemulsion: Development and optimization for dry eye disease treatment
(Elsevier, 2020)
Abstract: Inflammation plays a key role in dry eye disease (DED)
affecting millions of people worldwide. Non-steroidal anti-inflammatory
drugs (NSAIDs) can be used topically to act on the inflammatory component
of DED, ...
Soil erodibility in European mountain beech forests
(Canadian Science Publishing, 2021)
Forests in Europe are currently not endangered by soil erosion. However, this can change with climate change orwith intensified forest management practices. Using a newly established network of plots in beech forests across ...
Modulating Excited Charge-Transfer States of G‑Quartet Self- Assemblies by Earth Alkaline Cations and Hydration
(American Chemical Society (ACS), 2020)
Guanine self-assemblies are promising supramolecularplatforms for optoelectronic applications. The study (Hua et al., J. Phys. Chem. C 2012, 116, 14,682−14,689) reported that alkaline cations cannot modulate the electronic ...
Eliminating dissolution of platinum-based electrocatalysts at the atomic scale
(Nature Publishing Group, 2020)
A remaining challenge for deployment of proton-exchange membrane fuel cells is the
limited durability of Pt-nanoscale materials that operate at high voltages during the
cathodic oxygen reduction reaction. In this work, ...
Influence of C–H/X (X = S, Cl, N, Pt/Pd) Interactions on the Molecular and Crystal Structures of Pt(II) and Pd(II) Complexes with Thiomorpholine-4-carbonitrile: Crystallographic, Thermal, and DFT Study
(American Chemical Society (ACS), 2020)
Pt(II) and Pd(II) complexes (1 and 2, respectively) with thiomorpholine-4-carbonitrile (TM-CN), an N-substituted thiomorpholine derivative, were synthesized from tetrachlorido precursors in water. Structural analysis has ...
Dynamic stability of active sites in hydr(oxy)oxides for the oxygen evolution reaction
(Springer Science and Business Media LLC, 2020)
The poor activity and stability of electrode materials for the oxygen evolution reaction (OER) are the main bottlenecks in the water splitting reaction for H2 production. Here, by studying activity
stability trends for ...
Field Effect and Local Gating in Nitrogen‐Terminated Nanopores (NtNP) and Nanogaps (NtNG) in Graphene
(Wiley, 2021)
Single-molecule biosensing, with a promise of being applied in protein and DNA sequencing, could be achieved using tunneling current approach. Electrode-molecule-electrode tunneling current critically depends on whether ...