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Consequences of MnSOD interactions with nitric oxide: Nitric oxide dismutation and the generation of peroxynitrite and hydrogen peroxide
(USA :Taylor & Francis INC, 2007)
The present study demonstrates that manganese superoxide dismutase (MnSOD) Escherichia coli, binds nitric oxide (NO) and stimulates its decay under both anaerobic and aerobic conditions. The results indicate that previously ...
Mixed steroidal tetraoxanes induce apoptotic cell death in tumor cells
(Investigational New Drugs, 2009)
In this study we investigated the antiproliferative activity of six mixed steroidal tetraoxanes against various tumor cell lines, the toxicity against normal peripheral blood mononuclear cells (PBMC), and the mode of HeLa ...
Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities
(Elsevier, 2007)
The antiproliferative activity of previously synthesized (Z)-cholest-4-en-6-one oxime (1), (E)-cholest-4-en-6-one oxime (2), 7-aza-B-homocholest-4-en-6-one (3) and 6-aza-B-homocholest-4-en-7-one (4) and newly synthesized ...
Estrone derived steroidal diepoxide: Biologically active compound and precursor of a stable steroidal A,B-spiro system
(Elsevier Science Inc, New York, 2009)
A simple approach to a stable steroidal estrone derived A,B-spiro system is reported. Treatment of estrone derived A-ring diepoxyalcohol with the Ac2O-TMSOTf system at the ambient temperature led to acetylation, while at ...
Antiproliferative activity of β-hydroxy- β-arylalkanoic acids
(MDPI, 2007)
Article describes the synthesis of fifteen β-hydroxy- β-arylalkanoic acids by Reformatsky reaction using the 1-ethoxyethyl-2- bromoalkanoates, aromatic or cycloalkyl ketones or aromatic aldehydes. The short survey of ...
Immobilization of glucoamylase via its carbohydrate moiety on macroporous poly(GMA-co-EGDMA)
(Elsevier, 2007)
We succeeded in the immobilization of 190 mg of periodate oxidized glucoamylase per gram of macroporous polymer. The covalently immobilized enzyme had a specific activity of 1100 U/g. The temperature and pH optimum as well ...
Different responses of mesenteric artery from normotensive and spontaneously hypertensive rats to nitric oxide and its redox congeners
(Springer, 2007)
The conversion of nitric oxide (NO
) into its congeners nitrosonium (NO ) and nitroxyl (HNO/NO) ions may have important consequences for signal transduction and physiological responses. Manganese-containing superoxide ...
Investigation of interactions between surface water and petroleum-type pollutants
(Ecomed Publishers, Landsberg, 2005)
Background, Aims and Scope. In oil spill investigations, one of the most important steps is a proper choice of approaches that imply an investigation of samples taken from different sedimentary environments, samples of oil ...
Purification and properties of midgut α-amylase isolated from Morimus funereus (Coleoptera: Cerambycidae) larvae
(Elsevier Science Inc, New York, 2008)
Using soluble starch as a substrate five isoforms of α-amylase were identified in a crude extract of Morimus funereus larvae. The main α-amylase (termed AMF-3) was purified by gel filtration chromatography and anion exchange ...
High-yield synthesis of substituted and unsubstituted pyridinium salts containing a 4-oxothiazolidine moiety
(Georg Thieme Verlag Kg, Stuttgart, 2008)
A new series of unsubstituted and substituted pyridinium salts bearing a 4-oxothiazolidinyl moiety has been prepared by an efficient rearrangement of 2-(l-bromoalkylidene)thiazolidin-4-ones. The process is based on three ...