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A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype A metalloprotease
(American Chemical Society (ACS), 2007)
We previously identified structurally diverse small molecule (non-peptidic) inhibitors (SMNPIs) of the botulinum neurotoxin serotype A (BoNT/A) light chain (LC). Of these, several (including antimalarial drugs) contained ...
Determination of glass temperature of polymers by inverse gas chromatography
(Elsevier, 2008)
Inverse gas chromatography (IGC) is an attractive technique for polymer characterization due to possible simultaneous determination of various physicochemical properties of polymer systems merely from retention times of ...
Photocatalytic properties of TiO2/WO3 coatings formed by plasma electrolytic oxidation of titanium in 12-tungstosilicic acid
(Elsevier, 2012)
In this paper, we have investigated photocatalytic properties of TiO2/WO3 coatings formed by plasma electrolytic oxidation (PEO) of titanium in 12-tungstosilicic acid water solution and compared with photocatalytic activity ...
Purification and characterisation of Saccharomyces cerevisiae external invertase isoforms
(Elsevier Sci Ltd, Oxford, 2010)
Four external invertase isoforms (EINV1, EINV2, EINV3 and EINV4) from Saccharomyces cerevisiae were highly purified by isoelectric precipitation, ethanol precipitation, ion-exchange on QAE-Sephadex and gel filtration using ...
Removal of organically bound sulfur from oil shale by iron(III)-ion generated-regenerated from pyrite by the action of Acidithiobacillus ferrooxidans - Research on a model system
(Elsevier, 2008)
Oil shale is one of the alternative sources of hydrocarbon fuels ("synthetic petroleum") but is characterized by increased sulfur and nitrogen contents, which represent even greater ecological problems in its use compared ...
Cell wall invertase immobilization within calcium alginate beads
(Elsevier, 2007)
Yeast cell wall invertase (CWI) was immobilized within calcium alginate beads. The result of entrapment was the complete immobilization of all the added CWI. Three types of biocatalysts were prepared: CWI-S, CWI-155 and ...
Superior capacitive and electrocatalytic properties of carbonized nanostructured polyaniline upon a low-temperature hydrothermal treatment
(Oxford : Pergamon-Elsevier Science Ltd, 2013)
Carbonized nanostructured polyaniline (C.PANI) was hydrothermally treated in 1 mol dm(-3) KOH at 200 degrees C. The treatment caused significant reduction of micropore volume but negligible changes in mesoporous domain, ...
Supercritical carbon dioxide extraction of antioxidant fractions from selected Lamiaceae herbs and their antioxidant capacity
(Elsevier Sci Ltd, Oxford, 2010)
Antioxidant fractions from four herb spices belonging to the Lamiaceae family: rosemary (Rosmarinus officinalis), sage (Salvia officinalis), thyme (Thymus vulgaris) and hyssop (Hyssop officinalis) were isolated using ...
Alumina/silica supported K2CO3 as a catalyst for biodiesel synthesis from sunflower oil
(Elsevier Sci Ltd, Oxford, 2009)
The new type of catalyst for fatty acid methyl esters (FAME or biodiesel) synthesis with K2CO3 as active component on alumina/silica support was synthesized using sol-gel method. Corresponding catalyst (xerogel) was prepared ...
A Chemotype That Inhibits Three Unrelated Pathogenic Targets: The Botulinum Neurotoxin Serotype A Light Chain, P. falciparum Malaria, and the Ebola Filovirus
(American Chemical Society (ACS), 2011)
A 1,7-bis(alkylamino)diazachrysene-based small molecule was previously identified as an inhibitor of the botulinum neurotoxin serotype A light chain metalloprotease. Subsequently, a variety of derivatives of this chemotype ...