Menković, Nebojša

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Authority KeyName Variants
46057f6e-de50-4a1f-b0b3-bb23f22aa72c
  • Menković, Nebojša (33)
Projects
Traditional and new products of cultivated and wild growing fruits and grape vines, and by-products durring processing, with special emphasis on indigenous varieties: chemical characterization and biological profile Natural products of wild, cultivated and edible plants: structure and bioactivity determination
Sekundarni metaboliti samoniklih, lekovitih biljaka: izolovanje, karakterizacija i biloška aktivnost Ispitivanje lekovitog potencijala biljaka: morfološka, hemijska i farmakološka karakterizacija
Biljni proizvodi u preventivi i terapiji nezaraznih hroničnih oboljenja kod ljudi Characterization and application of fungal metabolites and assessment of new biofungicides potential
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200003 (Institute for Medicinal Plant Research 'Dr. Josif Pančić ', Belgrade) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM)
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200116 (University of Belgrade, Faculty of Agriculture) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200168 (University of Belgrade, Faculty of Chemistry)
Identification of predictive molecular markers for cancer progression, response to therapy and disease outcome Studying climate change and its influence on environment: impacts, adaptation and mitigation
Istraživanje dejstava modifikatora biološkog odgovora u fiziološkim i patološkim stanjima The application of new genotypes and technological innovations for the purpose of improvement of fruit-growing and viticultural production
Ministry for Science and Technology of Serbia (grant No. S. 4. 03. 38. 259-Pp2) Ministry for Science and Technology, Republic of Serbia
Project MESTD, br. 1755 Serbian Ministry of Science and Technology
Serbian Ministry of Science(TR-6937A)

Author's Bibliography

P2X7‐Receptor Pathway Involvement in the Anti‐Inflammatory Activity of Medicinal Plants

Ortiz, Sergio; Šavikin, Katarina; Massicot, France; Olivier, Elodie; Dutot, Melody; Rat, Patrice; Deguin, Brigitte; Gođevac, Dejan; Menković, Nebojša; Živković, Jelena; Zdunić, Gordana; Boutefnouchet, Sabrina

(Wiley, 2023)

TY  - JOUR
AU  - Ortiz, Sergio
AU  - Šavikin, Katarina
AU  - Massicot, France
AU  - Olivier, Elodie
AU  - Dutot, Melody
AU  - Rat, Patrice
AU  - Deguin, Brigitte
AU  - Gođevac, Dejan
AU  - Menković, Nebojša
AU  - Živković, Jelena
AU  - Zdunić, Gordana
AU  - Boutefnouchet, Sabrina
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7218
AB  - Medicinal plants used in European folk medicine attached to Lamiales, Gentianales or Asterales orders are used to treat inflammatory disorders. Many targets have been identified but to date, implication of purinergic receptor P2X7 activation has not yet been investigated. We managed to evaluate the protective effect on P2X7 activation by plant extracts used as anti-inflammatory in European folk medicine by the YO-PRO-1 uptake dye in vitro bioassay. Results revealed that among our selected plants, species from Scrophularia and Plantago genus were able to decrease significantly P2X7 activation (>50 % at 0.1 and 1 μg/mL). UPLC/MS, dereplication and metabolomic analysis of Scrophularia extracts, allowed us to identify the cinnamoyl-iridoid harpagoside as putative inhibitor of P2X7 activation. These results open a new research field regarding the anti-inflammatory mechanism of cinnamoyl-iridoids bearing plants, which may involve the P2X7 receptor.
PB  - Wiley
T2  - Chemistry & Biodiversity
T1  - P2X7‐Receptor Pathway Involvement in the Anti‐Inflammatory Activity of Medicinal Plants
VL  - 20
IS  - 8
DO  - 10.1002/cbdv.202300427
ER  - 
@article{
author = "Ortiz, Sergio and Šavikin, Katarina and Massicot, France and Olivier, Elodie and Dutot, Melody and Rat, Patrice and Deguin, Brigitte and Gođevac, Dejan and Menković, Nebojša and Živković, Jelena and Zdunić, Gordana and Boutefnouchet, Sabrina",
year = "2023",
abstract = "Medicinal plants used in European folk medicine attached to Lamiales, Gentianales or Asterales orders are used to treat inflammatory disorders. Many targets have been identified but to date, implication of purinergic receptor P2X7 activation has not yet been investigated. We managed to evaluate the protective effect on P2X7 activation by plant extracts used as anti-inflammatory in European folk medicine by the YO-PRO-1 uptake dye in vitro bioassay. Results revealed that among our selected plants, species from Scrophularia and Plantago genus were able to decrease significantly P2X7 activation (>50 % at 0.1 and 1 μg/mL). UPLC/MS, dereplication and metabolomic analysis of Scrophularia extracts, allowed us to identify the cinnamoyl-iridoid harpagoside as putative inhibitor of P2X7 activation. These results open a new research field regarding the anti-inflammatory mechanism of cinnamoyl-iridoids bearing plants, which may involve the P2X7 receptor.",
publisher = "Wiley",
journal = "Chemistry & Biodiversity",
title = "P2X7‐Receptor Pathway Involvement in the Anti‐Inflammatory Activity of Medicinal Plants",
volume = "20",
number = "8",
doi = "10.1002/cbdv.202300427"
}
Ortiz, S., Šavikin, K., Massicot, F., Olivier, E., Dutot, M., Rat, P., Deguin, B., Gođevac, D., Menković, N., Živković, J., Zdunić, G.,& Boutefnouchet, S.. (2023). P2X7‐Receptor Pathway Involvement in the Anti‐Inflammatory Activity of Medicinal Plants. in Chemistry & Biodiversity
Wiley., 20(8).
https://doi.org/10.1002/cbdv.202300427
Ortiz S, Šavikin K, Massicot F, Olivier E, Dutot M, Rat P, Deguin B, Gođevac D, Menković N, Živković J, Zdunić G, Boutefnouchet S. P2X7‐Receptor Pathway Involvement in the Anti‐Inflammatory Activity of Medicinal Plants. in Chemistry & Biodiversity. 2023;20(8).
doi:10.1002/cbdv.202300427 .
Ortiz, Sergio, Šavikin, Katarina, Massicot, France, Olivier, Elodie, Dutot, Melody, Rat, Patrice, Deguin, Brigitte, Gođevac, Dejan, Menković, Nebojša, Živković, Jelena, Zdunić, Gordana, Boutefnouchet, Sabrina, "P2X7‐Receptor Pathway Involvement in the Anti‐Inflammatory Activity of Medicinal Plants" in Chemistry & Biodiversity, 20, no. 8 (2023),
https://doi.org/10.1002/cbdv.202300427 . .
1

Phytochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia

Milosavljević, Saša; Jadranin, Milka; Mladenović, Mića; Tešević, Vele; Menković, Nebojša; Mutavdžić, Dragoslav; Krstić, Gordana

(North Macedonia : Society of Chemists and Technologists of Macedonia, 2021)

TY  - JOUR
AU  - Milosavljević, Saša
AU  - Jadranin, Milka
AU  - Mladenović, Mića
AU  - Tešević, Vele
AU  - Menković, Nebojša
AU  - Mutavdžić, Dragoslav
AU  - Krstić, Gordana
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4681
AB  - The aim of this research was to verify the authenticity of monofloral honeys from the territory of the Republic of Serbia on the basis of physicochemical parameters routinely measured in honey quality control using multivariate analysis. Seventeen samples of monofloral honey (11 samples of acacia honey and 6 samples of sunflower honey) from the territory of the Republic of Serbia were analyzed. Physico-chemical analysis of the samples included the examination of basic quality parameters and qualitative and quantitative analyses of phenolic compounds. In the samples tested, a total of 93 phenolic compounds were tentatively identified, and 19 of them were quantified. The obtained physicochemical analysis of the data served as input for the multivariate analysis. The hеаt map, which is useful for visualizing numerical data, was used for this purpose. The obtained results showed that the applied data can serve to clearly separate acacia and sunflower honeys.
AB  - Целта на ова истражување е да се потврди автентичноста на моноцветен мед од територијата на Република Србија врз основа на физичкохемиските параметри што рутински се мерат при контрола на квалитет на мед со примена на мултиваријантна анализа. Беа анализирани 17 примероци на моноцветен мед (11 примероци мед од акација и 6 примероци мед од сончоглед) од територијата на Република Србија. Физичкохемиските анализа на примероците вклучуваа испитување на основните параметри за квалитет како и квалитативна и квантитативна анализа на фенолните соединенија. Во примероците што беа тестирани, хипотетички беа идентификувани вкупно 93 фенолни соединенија, а 19 од нив беа и квантификувани. Добиените податоци од физичкохемиска анализа на овие податоци беа употребени како влезна податоци за мултиваријантна анализа. Беше применета топлинска мапа која е корисна за визуализација на нумеричките податоци. Добиените резултати покажуваат дека применетите податоци може да послужат за јасно да се раздели медот од акација и од сончоглед.
PB  - North Macedonia : Society of Chemists and Technologists of Macedonia
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Phytochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia
T1  - Физичкохемијски параметри како индикатори на автентичноста на монофлорален мед од територијата на Република Србија
VL  - 40
IS  - 1
DO  - 10.20450/mjcce.2021.2186
ER  - 
@article{
author = "Milosavljević, Saša and Jadranin, Milka and Mladenović, Mića and Tešević, Vele and Menković, Nebojša and Mutavdžić, Dragoslav and Krstić, Gordana",
year = "2021",
abstract = "The aim of this research was to verify the authenticity of monofloral honeys from the territory of the Republic of Serbia on the basis of physicochemical parameters routinely measured in honey quality control using multivariate analysis. Seventeen samples of monofloral honey (11 samples of acacia honey and 6 samples of sunflower honey) from the territory of the Republic of Serbia were analyzed. Physico-chemical analysis of the samples included the examination of basic quality parameters and qualitative and quantitative analyses of phenolic compounds. In the samples tested, a total of 93 phenolic compounds were tentatively identified, and 19 of them were quantified. The obtained physicochemical analysis of the data served as input for the multivariate analysis. The hеаt map, which is useful for visualizing numerical data, was used for this purpose. The obtained results showed that the applied data can serve to clearly separate acacia and sunflower honeys., Целта на ова истражување е да се потврди автентичноста на моноцветен мед од територијата на Република Србија врз основа на физичкохемиските параметри што рутински се мерат при контрола на квалитет на мед со примена на мултиваријантна анализа. Беа анализирани 17 примероци на моноцветен мед (11 примероци мед од акација и 6 примероци мед од сончоглед) од територијата на Република Србија. Физичкохемиските анализа на примероците вклучуваа испитување на основните параметри за квалитет како и квалитативна и квантитативна анализа на фенолните соединенија. Во примероците што беа тестирани, хипотетички беа идентификувани вкупно 93 фенолни соединенија, а 19 од нив беа и квантификувани. Добиените податоци од физичкохемиска анализа на овие податоци беа употребени како влезна податоци за мултиваријантна анализа. Беше применета топлинска мапа која е корисна за визуализација на нумеричките податоци. Добиените резултати покажуваат дека применетите податоци може да послужат за јасно да се раздели медот од акација и од сончоглед.",
publisher = "North Macedonia : Society of Chemists and Technologists of Macedonia",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Phytochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia, Физичкохемијски параметри како индикатори на автентичноста на монофлорален мед од територијата на Република Србија",
volume = "40",
number = "1",
doi = "10.20450/mjcce.2021.2186"
}
Milosavljević, S., Jadranin, M., Mladenović, M., Tešević, V., Menković, N., Mutavdžić, D.,& Krstić, G.. (2021). Phytochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia. in Macedonian Journal of Chemistry and Chemical Engineering
North Macedonia : Society of Chemists and Technologists of Macedonia., 40(1).
https://doi.org/10.20450/mjcce.2021.2186
Milosavljević S, Jadranin M, Mladenović M, Tešević V, Menković N, Mutavdžić D, Krstić G. Phytochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia. in Macedonian Journal of Chemistry and Chemical Engineering. 2021;40(1).
doi:10.20450/mjcce.2021.2186 .
Milosavljević, Saša, Jadranin, Milka, Mladenović, Mića, Tešević, Vele, Menković, Nebojša, Mutavdžić, Dragoslav, Krstić, Gordana, "Phytochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia" in Macedonian Journal of Chemistry and Chemical Engineering, 40, no. 1 (2021),
https://doi.org/10.20450/mjcce.2021.2186 . .
3
3

Varietal differences of Prokupac, Evita and Čokot Zemun based on their anthocyanins content in grape skin extract

Živković, Jelena; Jadranin, Milka; Przić, Zoran; Marković, Nebojša; Sokolović, Danijel; Savikin, Katarina; Menković, Nebojša

(2021)

TY  - JOUR
AU  - Živković, Jelena
AU  - Jadranin, Milka
AU  - Przić, Zoran
AU  - Marković, Nebojša
AU  - Sokolović, Danijel
AU  - Savikin, Katarina
AU  - Menković, Nebojša
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4249
AB  - In this study we have analyzed the anthocyanin composition of skin extracts of three red grape varieties Prokupac, Evita and Čokot Zemun in order to distinguish these cultivars based on their anthocyanin profile. Also, mechanical analysis of grape bunches and berries was performed. According to our results, seventeen anthocyanins were identified using LC‐MS technique and quantitative differences were recorded using HPLC‐DAD method. The highest content of total anthocyanins was obtained for Evita variety and the lowest one was recorded in Prokupac. Also, clear differences were observed in anthocyanins ratios. In comparison to Prokupac and Evita varieties, Čokot Zemun was characterized with a high content of cumaroyl derivatives of anthocyanin compounds, while high levels of acetylated derivatives were recorded in Prokupac. Data reported in this study represent a certain contribution to a database of mechanical properties and chemical composition of grape varieties originating from Balkan.
T2  - Chemistry & Biodiversity
T1  - Varietal differences of Prokupac, Evita and Čokot Zemun based on their anthocyanins content in grape skin extract
DO  - 10.1002/cbdv.202000858
ER  - 
@article{
author = "Živković, Jelena and Jadranin, Milka and Przić, Zoran and Marković, Nebojša and Sokolović, Danijel and Savikin, Katarina and Menković, Nebojša",
year = "2021",
abstract = "In this study we have analyzed the anthocyanin composition of skin extracts of three red grape varieties Prokupac, Evita and Čokot Zemun in order to distinguish these cultivars based on their anthocyanin profile. Also, mechanical analysis of grape bunches and berries was performed. According to our results, seventeen anthocyanins were identified using LC‐MS technique and quantitative differences were recorded using HPLC‐DAD method. The highest content of total anthocyanins was obtained for Evita variety and the lowest one was recorded in Prokupac. Also, clear differences were observed in anthocyanins ratios. In comparison to Prokupac and Evita varieties, Čokot Zemun was characterized with a high content of cumaroyl derivatives of anthocyanin compounds, while high levels of acetylated derivatives were recorded in Prokupac. Data reported in this study represent a certain contribution to a database of mechanical properties and chemical composition of grape varieties originating from Balkan.",
journal = "Chemistry & Biodiversity",
title = "Varietal differences of Prokupac, Evita and Čokot Zemun based on their anthocyanins content in grape skin extract",
doi = "10.1002/cbdv.202000858"
}
Živković, J., Jadranin, M., Przić, Z., Marković, N., Sokolović, D., Savikin, K.,& Menković, N.. (2021). Varietal differences of Prokupac, Evita and Čokot Zemun based on their anthocyanins content in grape skin extract. in Chemistry & Biodiversity.
https://doi.org/10.1002/cbdv.202000858
Živković J, Jadranin M, Przić Z, Marković N, Sokolović D, Savikin K, Menković N. Varietal differences of Prokupac, Evita and Čokot Zemun based on their anthocyanins content in grape skin extract. in Chemistry & Biodiversity. 2021;.
doi:10.1002/cbdv.202000858 .
Živković, Jelena, Jadranin, Milka, Przić, Zoran, Marković, Nebojša, Sokolović, Danijel, Savikin, Katarina, Menković, Nebojša, "Varietal differences of Prokupac, Evita and Čokot Zemun based on their anthocyanins content in grape skin extract" in Chemistry & Biodiversity (2021),
https://doi.org/10.1002/cbdv.202000858 . .
1

Phenolic and mineral profile of Balkan indigenous apple and pear cultivars

Živković, Jelena Č.; Savikin, Katarina; Zdunić, Gordana; Dojčinović, Biljana; Menković, Nebojša

(Serbian Chemical Society, 2016)

TY  - JOUR
AU  - Živković, Jelena Č.
AU  - Savikin, Katarina
AU  - Zdunić, Gordana
AU  - Dojčinović, Biljana
AU  - Menković, Nebojša
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1873
AB  - The aim of this study was the determination of phenolic compounds, and mineral nutrients in the pulp and peel obtained from Balkan indigenous apple and pear cultivars. The phenolic composition, assessed by HPLC-DAD and spectrophotometric methods varied significantly between the cultivars for both peel and pulp. Among the apples, the Mekica cultivar had the highest total phenolic content while Secerlija and Zlatna Parmenka had the lowest. In the case of the pear samples, the maximum total phenolic content was found in Crna Takisa while the minimum content was recorded for Bela Arapka. In most of the investigated samples, chlorogenic acid in apples and arbutin in pears were the major detected polyphenolic compounds. With regard to the mineral analysis, K was the most abundant followed by P, Mg, Ca and S. Iron was the dominant microelement in apple peel and pulp samples, while in pear samples the principal microelement was B. The obtained results provide detailed information on the chemical composition of the tested apple and pear cultivars and thereby, could encourage their wider cultivation and consumption.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Phenolic and mineral profile of Balkan indigenous apple and pear cultivars
VL  - 81
IS  - 6
SP  - 607
EP  - 621
DO  - 10.2298/JSC151026023Z
ER  - 
@article{
author = "Živković, Jelena Č. and Savikin, Katarina and Zdunić, Gordana and Dojčinović, Biljana and Menković, Nebojša",
year = "2016",
abstract = "The aim of this study was the determination of phenolic compounds, and mineral nutrients in the pulp and peel obtained from Balkan indigenous apple and pear cultivars. The phenolic composition, assessed by HPLC-DAD and spectrophotometric methods varied significantly between the cultivars for both peel and pulp. Among the apples, the Mekica cultivar had the highest total phenolic content while Secerlija and Zlatna Parmenka had the lowest. In the case of the pear samples, the maximum total phenolic content was found in Crna Takisa while the minimum content was recorded for Bela Arapka. In most of the investigated samples, chlorogenic acid in apples and arbutin in pears were the major detected polyphenolic compounds. With regard to the mineral analysis, K was the most abundant followed by P, Mg, Ca and S. Iron was the dominant microelement in apple peel and pulp samples, while in pear samples the principal microelement was B. The obtained results provide detailed information on the chemical composition of the tested apple and pear cultivars and thereby, could encourage their wider cultivation and consumption.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Phenolic and mineral profile of Balkan indigenous apple and pear cultivars",
volume = "81",
number = "6",
pages = "607-621",
doi = "10.2298/JSC151026023Z"
}
Živković, J. Č., Savikin, K., Zdunić, G., Dojčinović, B.,& Menković, N.. (2016). Phenolic and mineral profile of Balkan indigenous apple and pear cultivars. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 81(6), 607-621.
https://doi.org/10.2298/JSC151026023Z
Živković JČ, Savikin K, Zdunić G, Dojčinović B, Menković N. Phenolic and mineral profile of Balkan indigenous apple and pear cultivars. in Journal of the Serbian Chemical Society. 2016;81(6):607-621.
doi:10.2298/JSC151026023Z .
Živković, Jelena Č., Savikin, Katarina, Zdunić, Gordana, Dojčinović, Biljana, Menković, Nebojša, "Phenolic and mineral profile of Balkan indigenous apple and pear cultivars" in Journal of the Serbian Chemical Society, 81, no. 6 (2016):607-621,
https://doi.org/10.2298/JSC151026023Z . .
5
4

Phenolic compounds and carotenoids in pumpkin fruit and related traditional products

Zdunić, Gordana; Menković, Nebojša; Jadranin, Milka; Novaković, Miroslav; Savikin, Katarina P.; Živković, Jelena Č.

(Association of Chemical Engineers of Serbia, 2016)

TY  - JOUR
AU  - Zdunić, Gordana
AU  - Menković, Nebojša
AU  - Jadranin, Milka
AU  - Novaković, Miroslav
AU  - Savikin, Katarina P.
AU  - Živković, Jelena Č.
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1894
AB  - Pumpkin fruit is used in a diet since ancient times especially in rural communities. The major contributory factors of nutritional and medicinal value of pumpkins are carotenoids, polysaccharides, vitamins, minerals, and phenolic compounds. Due to a very large fruit that it is not easy to consume a whole as well as short shelf-life of fresh-cut pumpkin, different ways of conserving and processing are performed. In our study, total carotenoids, total phenolics and individual phenolics in fresh pumpkin and pumpkin traditional products such as sweet in wine, jam and juice, which are typical for northern parts of Serbia, were studied. Total carotenoids ranged from 27.6 mu g/g of pumpkin sweet in wine to 86.3 mu g/g of fresh fruit, while the amount of total phenolics varied between 93.0 mu g GAE/g of pumpkin juice and 905.9 mu g GAE/g of fresh fruit. Eight phenolic compounds were identified in the investigated samples and among them phenolic acids dominated. Among flavonoids, flavanon glycoside hesperidin was detected.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Phenolic compounds and carotenoids in pumpkin fruit and related traditional products
VL  - 70
IS  - 4
SP  - 429
EP  - 433
DO  - 10.2298/HEMIND150219049Z
ER  - 
@article{
author = "Zdunić, Gordana and Menković, Nebojša and Jadranin, Milka and Novaković, Miroslav and Savikin, Katarina P. and Živković, Jelena Č.",
year = "2016",
abstract = "Pumpkin fruit is used in a diet since ancient times especially in rural communities. The major contributory factors of nutritional and medicinal value of pumpkins are carotenoids, polysaccharides, vitamins, minerals, and phenolic compounds. Due to a very large fruit that it is not easy to consume a whole as well as short shelf-life of fresh-cut pumpkin, different ways of conserving and processing are performed. In our study, total carotenoids, total phenolics and individual phenolics in fresh pumpkin and pumpkin traditional products such as sweet in wine, jam and juice, which are typical for northern parts of Serbia, were studied. Total carotenoids ranged from 27.6 mu g/g of pumpkin sweet in wine to 86.3 mu g/g of fresh fruit, while the amount of total phenolics varied between 93.0 mu g GAE/g of pumpkin juice and 905.9 mu g GAE/g of fresh fruit. Eight phenolic compounds were identified in the investigated samples and among them phenolic acids dominated. Among flavonoids, flavanon glycoside hesperidin was detected.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Phenolic compounds and carotenoids in pumpkin fruit and related traditional products",
volume = "70",
number = "4",
pages = "429-433",
doi = "10.2298/HEMIND150219049Z"
}
Zdunić, G., Menković, N., Jadranin, M., Novaković, M., Savikin, K. P.,& Živković, J. Č.. (2016). Phenolic compounds and carotenoids in pumpkin fruit and related traditional products. in Hemijska industrija
Association of Chemical Engineers of Serbia., 70(4), 429-433.
https://doi.org/10.2298/HEMIND150219049Z
Zdunić G, Menković N, Jadranin M, Novaković M, Savikin KP, Živković JČ. Phenolic compounds and carotenoids in pumpkin fruit and related traditional products. in Hemijska industrija. 2016;70(4):429-433.
doi:10.2298/HEMIND150219049Z .
Zdunić, Gordana, Menković, Nebojša, Jadranin, Milka, Novaković, Miroslav, Savikin, Katarina P., Živković, Jelena Č., "Phenolic compounds and carotenoids in pumpkin fruit and related traditional products" in Hemijska industrija, 70, no. 4 (2016):429-433,
https://doi.org/10.2298/HEMIND150219049Z . .
1
34
15
39

Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac

Živković, Jelena Č.; Savikin, Katarina; Zdunić, Gordana; Gođevac, Dejan; Marković, Nebojsa; Pržić, Zoran; Menković, Nebojša

(Serbian Chemical Society, 2016)

TY  - JOUR
AU  - Živković, Jelena Č.
AU  - Savikin, Katarina
AU  - Zdunić, Gordana
AU  - Gođevac, Dejan
AU  - Marković, Nebojsa
AU  - Pržić, Zoran
AU  - Menković, Nebojša
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1940
AB  - Wine quality depends mainly on the characteristics of the grape it is made of, and one of the attributes affecting wine composition is cluster and berry morphology. The aim of this study was to represent variability of the morphological characteristics between different clones of the autochthonous grape variety Prokupac and to perform chemical evaluation of wines obtained from them. Total phenolic content was generally low and it ranged from 33.0 to 114.5 mg GAE/100 mL. Six main anthocyanin compounds including malvidin as the main anthocyanidin were detected. Malvidin 3-O-glucoside was the most abundant anthocyanin with concentration of 59.8 to 101.7 mu g/mL. Clones 43/5 and 43/4 yielded highest quality wines. According to the results, clonal selection makes a significant difference in Prokupac wine quality. On the other hand, there is a minor dependance of wine quality parameters to variation in morphological attributes of clusters and berries (bunch weight, proportion of stem, berry and seed weight, skin, pulp and seed weight per berry).
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac
VL  - 81
IS  - 8
SP  - 883
EP  - 896
DO  - 10.2298/JSC151114033Z
ER  - 
@article{
author = "Živković, Jelena Č. and Savikin, Katarina and Zdunić, Gordana and Gođevac, Dejan and Marković, Nebojsa and Pržić, Zoran and Menković, Nebojša",
year = "2016",
abstract = "Wine quality depends mainly on the characteristics of the grape it is made of, and one of the attributes affecting wine composition is cluster and berry morphology. The aim of this study was to represent variability of the morphological characteristics between different clones of the autochthonous grape variety Prokupac and to perform chemical evaluation of wines obtained from them. Total phenolic content was generally low and it ranged from 33.0 to 114.5 mg GAE/100 mL. Six main anthocyanin compounds including malvidin as the main anthocyanidin were detected. Malvidin 3-O-glucoside was the most abundant anthocyanin with concentration of 59.8 to 101.7 mu g/mL. Clones 43/5 and 43/4 yielded highest quality wines. According to the results, clonal selection makes a significant difference in Prokupac wine quality. On the other hand, there is a minor dependance of wine quality parameters to variation in morphological attributes of clusters and berries (bunch weight, proportion of stem, berry and seed weight, skin, pulp and seed weight per berry).",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac",
volume = "81",
number = "8",
pages = "883-896",
doi = "10.2298/JSC151114033Z"
}
Živković, J. Č., Savikin, K., Zdunić, G., Gođevac, D., Marković, N., Pržić, Z.,& Menković, N.. (2016). Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 81(8), 883-896.
https://doi.org/10.2298/JSC151114033Z
Živković JČ, Savikin K, Zdunić G, Gođevac D, Marković N, Pržić Z, Menković N. Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac. in Journal of the Serbian Chemical Society. 2016;81(8):883-896.
doi:10.2298/JSC151114033Z .
Živković, Jelena Č., Savikin, Katarina, Zdunić, Gordana, Gođevac, Dejan, Marković, Nebojsa, Pržić, Zoran, Menković, Nebojša, "Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac" in Journal of the Serbian Chemical Society, 81, no. 8 (2016):883-896,
https://doi.org/10.2298/JSC151114033Z . .
1
1
1

Bioactive secondary metabolites in several genera of gentianaceae species from thè central regions of thè balkan peninsula

Šavikin, Katarina; Aljančić, Ivana; Vajs, Vlatka; Milosavljević, Slobodan; Jadranin, Milka; Đorđević, Iris; Menković, Nebojša

(Springer Berlin Heidelberg, 2015)

TY  - CHAP
AU  - Šavikin, Katarina
AU  - Aljančić, Ivana
AU  - Vajs, Vlatka
AU  - Milosavljević, Slobodan
AU  - Jadranin, Milka
AU  - Đorđević, Iris
AU  - Menković, Nebojša
PY  - 2015
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1835
AB  - The results are presented of phytochemical investigations, during the last decade, of some wild-growing species of the family Gentianaceae from Serbia and Montenegro. Some of the species investigated, members of the genera Gentiana, Gentianella, and Swertia, are endemic, and the emphasis in this report is on those exhibiting biological activities that could be regarded as a potential source of drugs. This review discusses more than fifty compounds, such as xanthones, secoiridoids, and C-glucoflavonoids.
PB  - Springer Berlin Heidelberg
T2  - The Gentianaceae - Volume 2: Biotechnology and Applications
T1  - Bioactive secondary metabolites in several genera of gentianaceae species from thè central regions of thè balkan peninsula
SP  - 319
EP  - 347
DO  - 10.1007/978-3-642-54102-5_14
ER  - 
@inbook{
author = "Šavikin, Katarina and Aljančić, Ivana and Vajs, Vlatka and Milosavljević, Slobodan and Jadranin, Milka and Đorđević, Iris and Menković, Nebojša",
year = "2015",
abstract = "The results are presented of phytochemical investigations, during the last decade, of some wild-growing species of the family Gentianaceae from Serbia and Montenegro. Some of the species investigated, members of the genera Gentiana, Gentianella, and Swertia, are endemic, and the emphasis in this report is on those exhibiting biological activities that could be regarded as a potential source of drugs. This review discusses more than fifty compounds, such as xanthones, secoiridoids, and C-glucoflavonoids.",
publisher = "Springer Berlin Heidelberg",
journal = "The Gentianaceae - Volume 2: Biotechnology and Applications",
booktitle = "Bioactive secondary metabolites in several genera of gentianaceae species from thè central regions of thè balkan peninsula",
pages = "319-347",
doi = "10.1007/978-3-642-54102-5_14"
}
Šavikin, K., Aljančić, I., Vajs, V., Milosavljević, S., Jadranin, M., Đorđević, I.,& Menković, N.. (2015). Bioactive secondary metabolites in several genera of gentianaceae species from thè central regions of thè balkan peninsula. in The Gentianaceae - Volume 2: Biotechnology and Applications
Springer Berlin Heidelberg., 319-347.
https://doi.org/10.1007/978-3-642-54102-5_14
Šavikin K, Aljančić I, Vajs V, Milosavljević S, Jadranin M, Đorđević I, Menković N. Bioactive secondary metabolites in several genera of gentianaceae species from thè central regions of thè balkan peninsula. in The Gentianaceae - Volume 2: Biotechnology and Applications. 2015;:319-347.
doi:10.1007/978-3-642-54102-5_14 .
Šavikin, Katarina, Aljančić, Ivana, Vajs, Vlatka, Milosavljević, Slobodan, Jadranin, Milka, Đorđević, Iris, Menković, Nebojša, "Bioactive secondary metabolites in several genera of gentianaceae species from thè central regions of thè balkan peninsula" in The Gentianaceae - Volume 2: Biotechnology and Applications (2015):319-347,
https://doi.org/10.1007/978-3-642-54102-5_14 . .
11
8

Further Amphoricarpolides from the Surface Extracts of Amphoricarpos Complex from Montenegro

Cvetković, Mirjana; Đorđević, Iris; Jadranin, Milka; Vajs, Vlatka; Vučković, Ivan; Menković, Nebojša; Milosavljević, Slobodan; Tešević, Vele

(Wiley-V C H Verlag Gmbh, Weinheim, 2014)

TY  - JOUR
AU  - Cvetković, Mirjana
AU  - Đorđević, Iris
AU  - Jadranin, Milka
AU  - Vajs, Vlatka
AU  - Vučković, Ivan
AU  - Menković, Nebojša
AU  - Milosavljević, Slobodan
AU  - Tešević, Vele
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1430
AB  - Analysis of composition of sesquiterpene lactone fraction of leaf cuticular neutral lipids of Amphoricarpos complex from two different localities in north Montenegro, i.e., canyon of river Tara (A. autariatus ssp. autariatus) and mountain Zeletin (A. autariatus ssp. bertisceus) afforded sesquiterpene lactones with guaianolide skeletons (17 compounds), so called amphoricarpolides, typical for this genus. Nine of them, 9-17, were new compounds, and their structures were elucidated by detailed analyses of IR, NMR, and MS data.
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - Chemistry & Biodiversity
T1  - Further Amphoricarpolides from the Surface Extracts of Amphoricarpos Complex from Montenegro
VL  - 11
IS  - 9
SP  - 1428
EP  - 1437
DO  - 10.1002/cbdv.201400101
ER  - 
@article{
author = "Cvetković, Mirjana and Đorđević, Iris and Jadranin, Milka and Vajs, Vlatka and Vučković, Ivan and Menković, Nebojša and Milosavljević, Slobodan and Tešević, Vele",
year = "2014",
abstract = "Analysis of composition of sesquiterpene lactone fraction of leaf cuticular neutral lipids of Amphoricarpos complex from two different localities in north Montenegro, i.e., canyon of river Tara (A. autariatus ssp. autariatus) and mountain Zeletin (A. autariatus ssp. bertisceus) afforded sesquiterpene lactones with guaianolide skeletons (17 compounds), so called amphoricarpolides, typical for this genus. Nine of them, 9-17, were new compounds, and their structures were elucidated by detailed analyses of IR, NMR, and MS data.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Chemistry & Biodiversity",
title = "Further Amphoricarpolides from the Surface Extracts of Amphoricarpos Complex from Montenegro",
volume = "11",
number = "9",
pages = "1428-1437",
doi = "10.1002/cbdv.201400101"
}
Cvetković, M., Đorđević, I., Jadranin, M., Vajs, V., Vučković, I., Menković, N., Milosavljević, S.,& Tešević, V.. (2014). Further Amphoricarpolides from the Surface Extracts of Amphoricarpos Complex from Montenegro. in Chemistry & Biodiversity
Wiley-V C H Verlag Gmbh, Weinheim., 11(9), 1428-1437.
https://doi.org/10.1002/cbdv.201400101
Cvetković M, Đorđević I, Jadranin M, Vajs V, Vučković I, Menković N, Milosavljević S, Tešević V. Further Amphoricarpolides from the Surface Extracts of Amphoricarpos Complex from Montenegro. in Chemistry & Biodiversity. 2014;11(9):1428-1437.
doi:10.1002/cbdv.201400101 .
Cvetković, Mirjana, Đorđević, Iris, Jadranin, Milka, Vajs, Vlatka, Vučković, Ivan, Menković, Nebojša, Milosavljević, Slobodan, Tešević, Vele, "Further Amphoricarpolides from the Surface Extracts of Amphoricarpos Complex from Montenegro" in Chemistry & Biodiversity, 11, no. 9 (2014):1428-1437,
https://doi.org/10.1002/cbdv.201400101 . .
6
7
7

Phenolic composition and free radical scavenging activity of wine produced from the Serbian autochthonous grape variety Prokupac - A model approach

Menković, Nebojša; Živković, Jelena Č.; Savikin, Katarina; Gođevac, Dejan; Zdunić, Gordana

(Serbian Chemical Society, 2014)

TY  - JOUR
AU  - Menković, Nebojša
AU  - Živković, Jelena Č.
AU  - Savikin, Katarina
AU  - Gođevac, Dejan
AU  - Zdunić, Gordana
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1546
AB  - Phenolic compounds are very important quality parameters of wine because of their impact on colour, taste and health properties. The present study was aimed at evaluating the general phenolic composition and free radical scavenging activity of aqueous and organic fractions obtained using liquid liquid extraction of red wine produced from the Serbian autochthonous grape variety Prokupac. The total phenolic contents in the different fractions ranged from 48.22 to 289.12 mg GAE per g dry fraction. Phenolic acids (mainly hydroxycinnamic acids) and quercetin 3-O-glucuronide were the main components in the EtOAc fraction at pH 2.0; catechins, phenolic acids (mainly hydroxybenzoic acids) and quercetin were found in the EtOAc fraction at pH 7.0, while anthocyanins were identified in the aqueous residue after EtOAc extraction. The major anthocyanin extracted into the aqueous fraction was malvidin-3-glucoside, while the most abundant non-anthocyanin phenolic compounds in the organic fractions were ethyl gallate and trans-caftaric acid. The radical scavenging activities of the fraction differed significantly and the IC50 values were 138.58 mu g mL(-1) for the aqueous fraction, 17.83 and 3.47 ng mL(-1) for the EtOAc fractions at pH 2.0 and 7.0, respectively. As the EtOAc fractions were found to be more potent radical scavengers, it could be assumed that non-anthocyanin phenolic compounds were responsible for such activity in Prokupac wine.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Phenolic composition and free radical scavenging activity of wine produced from the Serbian autochthonous grape variety Prokupac - A model approach
VL  - 79
IS  - 1
SP  - 11
EP  - 24
DO  - 10.2298/JSC130511089M
ER  - 
@article{
author = "Menković, Nebojša and Živković, Jelena Č. and Savikin, Katarina and Gođevac, Dejan and Zdunić, Gordana",
year = "2014",
abstract = "Phenolic compounds are very important quality parameters of wine because of their impact on colour, taste and health properties. The present study was aimed at evaluating the general phenolic composition and free radical scavenging activity of aqueous and organic fractions obtained using liquid liquid extraction of red wine produced from the Serbian autochthonous grape variety Prokupac. The total phenolic contents in the different fractions ranged from 48.22 to 289.12 mg GAE per g dry fraction. Phenolic acids (mainly hydroxycinnamic acids) and quercetin 3-O-glucuronide were the main components in the EtOAc fraction at pH 2.0; catechins, phenolic acids (mainly hydroxybenzoic acids) and quercetin were found in the EtOAc fraction at pH 7.0, while anthocyanins were identified in the aqueous residue after EtOAc extraction. The major anthocyanin extracted into the aqueous fraction was malvidin-3-glucoside, while the most abundant non-anthocyanin phenolic compounds in the organic fractions were ethyl gallate and trans-caftaric acid. The radical scavenging activities of the fraction differed significantly and the IC50 values were 138.58 mu g mL(-1) for the aqueous fraction, 17.83 and 3.47 ng mL(-1) for the EtOAc fractions at pH 2.0 and 7.0, respectively. As the EtOAc fractions were found to be more potent radical scavengers, it could be assumed that non-anthocyanin phenolic compounds were responsible for such activity in Prokupac wine.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Phenolic composition and free radical scavenging activity of wine produced from the Serbian autochthonous grape variety Prokupac - A model approach",
volume = "79",
number = "1",
pages = "11-24",
doi = "10.2298/JSC130511089M"
}
Menković, N., Živković, J. Č., Savikin, K., Gođevac, D.,& Zdunić, G.. (2014). Phenolic composition and free radical scavenging activity of wine produced from the Serbian autochthonous grape variety Prokupac - A model approach. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 79(1), 11-24.
https://doi.org/10.2298/JSC130511089M
Menković N, Živković JČ, Savikin K, Gođevac D, Zdunić G. Phenolic composition and free radical scavenging activity of wine produced from the Serbian autochthonous grape variety Prokupac - A model approach. in Journal of the Serbian Chemical Society. 2014;79(1):11-24.
doi:10.2298/JSC130511089M .
Menković, Nebojša, Živković, Jelena Č., Savikin, Katarina, Gođevac, Dejan, Zdunić, Gordana, "Phenolic composition and free radical scavenging activity of wine produced from the Serbian autochthonous grape variety Prokupac - A model approach" in Journal of the Serbian Chemical Society, 79, no. 1 (2014):11-24,
https://doi.org/10.2298/JSC130511089M . .
7
6
7

Morphological and chemical characterization of Arnica montana L. under different cultivation models

Pljevljakusic, Dejan; Janković, Teodora; Jelačić, Slavica C.; Novaković, Miroslav; Menković, Nebojša; Beatovic, Damir; Dajić-Stevanović, Zora

(Elsevier, 2014)

TY  - JOUR
AU  - Pljevljakusic, Dejan
AU  - Janković, Teodora
AU  - Jelačić, Slavica C.
AU  - Novaković, Miroslav
AU  - Menković, Nebojša
AU  - Beatovic, Damir
AU  - Dajić-Stevanović, Zora
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1536
AB  - Arnica (Arnica montana L) is a perennial mountain plant whose flower heads are mainly used for topical treatment of bruises and sprains in phytopharmaceutical preparations such as ointments, creams and gels. In this study, different models of arnica cultivation have been tested in three-year field trial arranged in 2 x 3 x 2 factorial design. Planting date (spring and autumn), fertilizater type (manure, NPK and control) and mode of reproduction (generative and clonal) were induced factors on the trial. The variation of the rosette diameter, flowering stem count and height, flower heads count and diameter, together with flower heads yield and chemical properties were investigated as morphological parameters. Spring planting of clonally propagated plants was showed to be the least successful model due to the low percent of rooted plants and weak shoot development. Other models yielded from 59.8 to 143.6 kg ha(-1) and 116.3 to 258.7 kg ha(-1) flower heads (dw) in the second and third year, respectively. Total sesquiterpene lactones content in flower heads of all tested variants was above the minimum of pharmacopeia quality regulation and ranged from 4.6 to 13.9 mg g(-1) depending on factor levels, while the amounts of two dominant flavonoid compounds quercetin-3-O-glucoside and kaempferol-3-O-glucoside ranged from 7.8 to 13.9 mg g(-1) and from 2.1 to 4.7 mg g(-1), respectively. All induced factors in the field trial significantly influenced variation in both morphological and chemical parameters, where fertilized variants from autumn planting have shown to be superior in flower heads yield with satisfying levels of the secondary metabolites content. Factorial analysis distinguished that half of morphological parameters positively correlated with flower heads yield. First three ranks of sequential classification of cultivation models with desirable properties were captured by variants planted in autumn, while the last rated variants were those from clonal propagation planted in spring. This attempt of arnica domestication in agroecological conditions of western Serbia has proven to be successful in ensuring high quality raw material, providing at the same time answers to the questions that have not been reviewed so far.
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - Morphological and chemical characterization of Arnica montana L. under different cultivation models
VL  - 52
SP  - 233
EP  - 244
DO  - 10.1016/j.indcrop.2013.10.035
ER  - 
@article{
author = "Pljevljakusic, Dejan and Janković, Teodora and Jelačić, Slavica C. and Novaković, Miroslav and Menković, Nebojša and Beatovic, Damir and Dajić-Stevanović, Zora",
year = "2014",
abstract = "Arnica (Arnica montana L) is a perennial mountain plant whose flower heads are mainly used for topical treatment of bruises and sprains in phytopharmaceutical preparations such as ointments, creams and gels. In this study, different models of arnica cultivation have been tested in three-year field trial arranged in 2 x 3 x 2 factorial design. Planting date (spring and autumn), fertilizater type (manure, NPK and control) and mode of reproduction (generative and clonal) were induced factors on the trial. The variation of the rosette diameter, flowering stem count and height, flower heads count and diameter, together with flower heads yield and chemical properties were investigated as morphological parameters. Spring planting of clonally propagated plants was showed to be the least successful model due to the low percent of rooted plants and weak shoot development. Other models yielded from 59.8 to 143.6 kg ha(-1) and 116.3 to 258.7 kg ha(-1) flower heads (dw) in the second and third year, respectively. Total sesquiterpene lactones content in flower heads of all tested variants was above the minimum of pharmacopeia quality regulation and ranged from 4.6 to 13.9 mg g(-1) depending on factor levels, while the amounts of two dominant flavonoid compounds quercetin-3-O-glucoside and kaempferol-3-O-glucoside ranged from 7.8 to 13.9 mg g(-1) and from 2.1 to 4.7 mg g(-1), respectively. All induced factors in the field trial significantly influenced variation in both morphological and chemical parameters, where fertilized variants from autumn planting have shown to be superior in flower heads yield with satisfying levels of the secondary metabolites content. Factorial analysis distinguished that half of morphological parameters positively correlated with flower heads yield. First three ranks of sequential classification of cultivation models with desirable properties were captured by variants planted in autumn, while the last rated variants were those from clonal propagation planted in spring. This attempt of arnica domestication in agroecological conditions of western Serbia has proven to be successful in ensuring high quality raw material, providing at the same time answers to the questions that have not been reviewed so far.",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "Morphological and chemical characterization of Arnica montana L. under different cultivation models",
volume = "52",
pages = "233-244",
doi = "10.1016/j.indcrop.2013.10.035"
}
Pljevljakusic, D., Janković, T., Jelačić, S. C., Novaković, M., Menković, N., Beatovic, D.,& Dajić-Stevanović, Z.. (2014). Morphological and chemical characterization of Arnica montana L. under different cultivation models. in Industrial Crops and Products
Elsevier., 52, 233-244.
https://doi.org/10.1016/j.indcrop.2013.10.035
Pljevljakusic D, Janković T, Jelačić SC, Novaković M, Menković N, Beatovic D, Dajić-Stevanović Z. Morphological and chemical characterization of Arnica montana L. under different cultivation models. in Industrial Crops and Products. 2014;52:233-244.
doi:10.1016/j.indcrop.2013.10.035 .
Pljevljakusic, Dejan, Janković, Teodora, Jelačić, Slavica C., Novaković, Miroslav, Menković, Nebojša, Beatovic, Damir, Dajić-Stevanović, Zora, "Morphological and chemical characterization of Arnica montana L. under different cultivation models" in Industrial Crops and Products, 52 (2014):233-244,
https://doi.org/10.1016/j.indcrop.2013.10.035 . .
22
12
19

Two structurally distinct chalcone dimers from Helichrysum zivojinii and their activities in cancer cell lines

Aljančić, Ivana; Vučković, Ivan; Jadranin, Milka; Pešić, Milica; Đorđević, Iris; Podolski-Renic, Ana; Stojkovic, Sonja; Menković, Nebojša; Vajs, Vlatka; Milosavljević, Slobodan

(Oxford : Pergamon-Elsevier Science Ltd, 2014)

TY  - JOUR
AU  - Aljančić, Ivana
AU  - Vučković, Ivan
AU  - Jadranin, Milka
AU  - Pešić, Milica
AU  - Đorđević, Iris
AU  - Podolski-Renic, Ana
AU  - Stojkovic, Sonja
AU  - Menković, Nebojša
AU  - Vajs, Vlatka
AU  - Milosavljević, Slobodan
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1542
AB  - Dimers tomoroside A (1) and tomoroside B (2) of the co-occuring known chalcone monomer (3), along with the seven known flavonoid glucosides (4-10), were isolated from the aerial parts of Helichrysum zivojinii Cernjavski & Soska. The structures of the isolated compounds were elucidated by spectroscopic techniques. Compound 1 inhibited topo Ha and hif-1 alpha expression and stimulated doxorubicin anticancer effect, while 2 increased the expression of hif-1 alpha a, probably acting as antioxidant and redox status modulator. Notably, 2 synergized with Tipifarnib showing potential to improve the action of this new chemotherapeutic involved in the modulation of mitogene activated protein (MAP) kinase signaling pathway.
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - Phytochemistry
T1  - Two structurally distinct chalcone dimers from Helichrysum zivojinii and their activities in cancer cell lines
VL  - 98
SP  - 190
EP  - 196
DO  - 10.1016/j.phytochem.2013.11.025
ER  - 
@article{
author = "Aljančić, Ivana and Vučković, Ivan and Jadranin, Milka and Pešić, Milica and Đorđević, Iris and Podolski-Renic, Ana and Stojkovic, Sonja and Menković, Nebojša and Vajs, Vlatka and Milosavljević, Slobodan",
year = "2014",
abstract = "Dimers tomoroside A (1) and tomoroside B (2) of the co-occuring known chalcone monomer (3), along with the seven known flavonoid glucosides (4-10), were isolated from the aerial parts of Helichrysum zivojinii Cernjavski & Soska. The structures of the isolated compounds were elucidated by spectroscopic techniques. Compound 1 inhibited topo Ha and hif-1 alpha expression and stimulated doxorubicin anticancer effect, while 2 increased the expression of hif-1 alpha a, probably acting as antioxidant and redox status modulator. Notably, 2 synergized with Tipifarnib showing potential to improve the action of this new chemotherapeutic involved in the modulation of mitogene activated protein (MAP) kinase signaling pathway.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Phytochemistry",
title = "Two structurally distinct chalcone dimers from Helichrysum zivojinii and their activities in cancer cell lines",
volume = "98",
pages = "190-196",
doi = "10.1016/j.phytochem.2013.11.025"
}
Aljančić, I., Vučković, I., Jadranin, M., Pešić, M., Đorđević, I., Podolski-Renic, A., Stojkovic, S., Menković, N., Vajs, V.,& Milosavljević, S.. (2014). Two structurally distinct chalcone dimers from Helichrysum zivojinii and their activities in cancer cell lines. in Phytochemistry
Oxford : Pergamon-Elsevier Science Ltd., 98, 190-196.
https://doi.org/10.1016/j.phytochem.2013.11.025
Aljančić I, Vučković I, Jadranin M, Pešić M, Đorđević I, Podolski-Renic A, Stojkovic S, Menković N, Vajs V, Milosavljević S. Two structurally distinct chalcone dimers from Helichrysum zivojinii and their activities in cancer cell lines. in Phytochemistry. 2014;98:190-196.
doi:10.1016/j.phytochem.2013.11.025 .
Aljančić, Ivana, Vučković, Ivan, Jadranin, Milka, Pešić, Milica, Đorđević, Iris, Podolski-Renic, Ana, Stojkovic, Sonja, Menković, Nebojša, Vajs, Vlatka, Milosavljević, Slobodan, "Two structurally distinct chalcone dimers from Helichrysum zivojinii and their activities in cancer cell lines" in Phytochemistry, 98 (2014):190-196,
https://doi.org/10.1016/j.phytochem.2013.11.025 . .
26
17
23

Secondary metabolites of three endemic Centaurea L. species

Tešević, Vele; Aljančić, Ivana; Milosavljević, Slobodan; Vajs, Vlatka; Đorđević, Iris; Jadranin, Milka; Menković, Nebojša; Matevski, Vlado

(Serbian Chemical Soc, Belgrade, 2014)

TY  - JOUR
AU  - Tešević, Vele
AU  - Aljančić, Ivana
AU  - Milosavljević, Slobodan
AU  - Vajs, Vlatka
AU  - Đorđević, Iris
AU  - Jadranin, Milka
AU  - Menković, Nebojša
AU  - Matevski, Vlado
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1478
AB  - The aerial parts of three endemic Centaurea L. species, namely C. tomorosii Micevski, C. soskae Hayek and C. galicicae Micevski, afforded the sesquiterpene lactone cnicin (1) and seven flavonoids: apigenin (2), isokaempferide (3), hispidulin (4), eupatorin (5), cirsimaritin (6), santoflavone (7) and salvigenin (8). The structures of the isolated compounds were determined by UV, H-1-NMR and C-13-NMR spectroscopy and HR-ESI-MS spectrometry. H-1-NMR spectroscopy was used as a method for the quantitative analysis of cnicin.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Secondary metabolites of three endemic Centaurea L. species
VL  - 79
IS  - 11
SP  - 1355
EP  - 1362
DO  - 10.2298/JSC140318048T
ER  - 
@article{
author = "Tešević, Vele and Aljančić, Ivana and Milosavljević, Slobodan and Vajs, Vlatka and Đorđević, Iris and Jadranin, Milka and Menković, Nebojša and Matevski, Vlado",
year = "2014",
abstract = "The aerial parts of three endemic Centaurea L. species, namely C. tomorosii Micevski, C. soskae Hayek and C. galicicae Micevski, afforded the sesquiterpene lactone cnicin (1) and seven flavonoids: apigenin (2), isokaempferide (3), hispidulin (4), eupatorin (5), cirsimaritin (6), santoflavone (7) and salvigenin (8). The structures of the isolated compounds were determined by UV, H-1-NMR and C-13-NMR spectroscopy and HR-ESI-MS spectrometry. H-1-NMR spectroscopy was used as a method for the quantitative analysis of cnicin.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Secondary metabolites of three endemic Centaurea L. species",
volume = "79",
number = "11",
pages = "1355-1362",
doi = "10.2298/JSC140318048T"
}
Tešević, V., Aljančić, I., Milosavljević, S., Vajs, V., Đorđević, I., Jadranin, M., Menković, N.,& Matevski, V.. (2014). Secondary metabolites of three endemic Centaurea L. species. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 79(11), 1355-1362.
https://doi.org/10.2298/JSC140318048T
Tešević V, Aljančić I, Milosavljević S, Vajs V, Đorđević I, Jadranin M, Menković N, Matevski V. Secondary metabolites of three endemic Centaurea L. species. in Journal of the Serbian Chemical Society. 2014;79(11):1355-1362.
doi:10.2298/JSC140318048T .
Tešević, Vele, Aljančić, Ivana, Milosavljević, Slobodan, Vajs, Vlatka, Đorđević, Iris, Jadranin, Milka, Menković, Nebojša, Matevski, Vlado, "Secondary metabolites of three endemic Centaurea L. species" in Journal of the Serbian Chemical Society, 79, no. 11 (2014):1355-1362,
https://doi.org/10.2298/JSC140318048T . .
11
10
11

Bioactive Compounds of Endemic Species Sideritis raeseri subsp raeseri Grown in National Park Galicica

Menković, Nebojša; Gođevac, Dejan; Savikin, Katarina; Zdunić, Gordana; Milosavljević, Slobodan; Bojadzi, Andon; Avramoski, Oliver

(ACG Publications, 2013)

TY  - JOUR
AU  - Menković, Nebojša
AU  - Gođevac, Dejan
AU  - Savikin, Katarina
AU  - Zdunić, Gordana
AU  - Milosavljević, Slobodan
AU  - Bojadzi, Andon
AU  - Avramoski, Oliver
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1333
AB  - Collection of Sideritis raeseri subsp. raeseri has a long tradition in local communities in the Ohrid-Prespa region. The aim of the present study was the analysis of bioactive compounds especially those with anti-inflammatory activity. Combination of the UV and MS data allowed the characterization of 17 compounds, which could be classified into flavonoid glycosides or hydroxycynnamic acid derivatives. Six of them were isolated using preparative HPLC: isoscutellarein 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-beta-D-glucopyranoside, 4'-O-methylhypolaetin 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-beta-D-glucopyranoside, hypolaetin 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-6 ''-O-acetyl-beta-D-glucopyranoside, 4'-O-methylisoscutellarein 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-beta-D-glucopyranoside, isoscutellarein 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-6 ''-O-acetyl-beta-D-glucopyranoside and 4'-O-methylhypolaetin 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-6 ''-O-acetyl-beta-D-glucopyranoside. The presence of phenylpropanoid glycoside martynoside was reported for the first time in the wild growing S. raeseri subsp. raeseri. Hypolaetin derivatives, known for their antiinflammatory activity, dominated and were more abundant in S. raeseri subsp. raeseri grown in NPG in comparison with S. scardica grown nearby the NPG. The type of solvent affected distribution and the amount of bioactive compounds and the advantage was given to less polar extracts which were richer in hypolaetin derivatives.
PB  - ACG Publications
T2  - Records of Natural Products
T1  - Bioactive Compounds of Endemic Species Sideritis raeseri subsp raeseri Grown in National Park Galicica
VL  - 7
IS  - 3
SP  - 161
EP  - 168
UR  - https://hdl.handle.net/21.15107/rcub_cer_1333
ER  - 
@article{
author = "Menković, Nebojša and Gođevac, Dejan and Savikin, Katarina and Zdunić, Gordana and Milosavljević, Slobodan and Bojadzi, Andon and Avramoski, Oliver",
year = "2013",
abstract = "Collection of Sideritis raeseri subsp. raeseri has a long tradition in local communities in the Ohrid-Prespa region. The aim of the present study was the analysis of bioactive compounds especially those with anti-inflammatory activity. Combination of the UV and MS data allowed the characterization of 17 compounds, which could be classified into flavonoid glycosides or hydroxycynnamic acid derivatives. Six of them were isolated using preparative HPLC: isoscutellarein 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-beta-D-glucopyranoside, 4'-O-methylhypolaetin 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-beta-D-glucopyranoside, hypolaetin 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-6 ''-O-acetyl-beta-D-glucopyranoside, 4'-O-methylisoscutellarein 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-beta-D-glucopyranoside, isoscutellarein 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-6 ''-O-acetyl-beta-D-glucopyranoside and 4'-O-methylhypolaetin 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-6 ''-O-acetyl-beta-D-glucopyranoside. The presence of phenylpropanoid glycoside martynoside was reported for the first time in the wild growing S. raeseri subsp. raeseri. Hypolaetin derivatives, known for their antiinflammatory activity, dominated and were more abundant in S. raeseri subsp. raeseri grown in NPG in comparison with S. scardica grown nearby the NPG. The type of solvent affected distribution and the amount of bioactive compounds and the advantage was given to less polar extracts which were richer in hypolaetin derivatives.",
publisher = "ACG Publications",
journal = "Records of Natural Products",
title = "Bioactive Compounds of Endemic Species Sideritis raeseri subsp raeseri Grown in National Park Galicica",
volume = "7",
number = "3",
pages = "161-168",
url = "https://hdl.handle.net/21.15107/rcub_cer_1333"
}
Menković, N., Gođevac, D., Savikin, K., Zdunić, G., Milosavljević, S., Bojadzi, A.,& Avramoski, O.. (2013). Bioactive Compounds of Endemic Species Sideritis raeseri subsp raeseri Grown in National Park Galicica. in Records of Natural Products
ACG Publications., 7(3), 161-168.
https://hdl.handle.net/21.15107/rcub_cer_1333
Menković N, Gođevac D, Savikin K, Zdunić G, Milosavljević S, Bojadzi A, Avramoski O. Bioactive Compounds of Endemic Species Sideritis raeseri subsp raeseri Grown in National Park Galicica. in Records of Natural Products. 2013;7(3):161-168.
https://hdl.handle.net/21.15107/rcub_cer_1333 .
Menković, Nebojša, Gođevac, Dejan, Savikin, Katarina, Zdunić, Gordana, Milosavljević, Slobodan, Bojadzi, Andon, Avramoski, Oliver, "Bioactive Compounds of Endemic Species Sideritis raeseri subsp raeseri Grown in National Park Galicica" in Records of Natural Products, 7, no. 3 (2013):161-168,
https://hdl.handle.net/21.15107/rcub_cer_1333 .
9
17

Sesquiterpene lactones of amphoricarpos autariatus ssp. autariatus from montenegro - Antifungal leaf - Surface constituents

Jadranin, Milka; Dordević, I.; Tešević, Vele; Vajs, Vlatka; Menković, Nebojša; Soković, Marina; Glamočlija, J.; Milosavljević, Slobodan

(ACG Publications, 2013)

TY  - JOUR
AU  - Jadranin, Milka
AU  - Dordević, I.
AU  - Tešević, Vele
AU  - Vajs, Vlatka
AU  - Menković, Nebojša
AU  - Soković, Marina
AU  - Glamočlija, J.
AU  - Milosavljević, Slobodan
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1381
AB  - The composition of leaf cuticular neutral lipids of Amphoricarpos autariatus ssp. autariatus collected at canyon of river Tara (North Montenegro) was investigated by GC/MS (nonpolar fraction), LC-ESI TOF MS and 1H NMR spectroscopy (more polar fraction). The nonpolar fraction (ca. 15% of the whole surface extract) contained C27 - 33 n-alkanes, those with odd-number of carbons predominating. The LC-ESI MS and 1H NMR of the more polar fraction revealed 13 sesquiterpene lactones, constituting ca. 97.5% of the lactone mixture, identified as the known guaianolides, so-called amphoricarpolides, found previously in the aerial parts of the genus. The lactone fraction exhibited considerable in vitro effect against eight fungi, i.e. Aspergillus ochraceus, A. niger, A. versicolor, Penicillium funiculosum, P. ochrochloron, Trichoderma viride, Fusarium verticillioides and Fulvia fulvum.
PB  - ACG Publications
T2  - Records of Natural Products
T1  - Sesquiterpene lactones of amphoricarpos autariatus ssp. autariatus from montenegro - Antifungal leaf - Surface constituents
VL  - 7
IS  - 3
SP  - 234
EP  - 238
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1360
ER  - 
@article{
author = "Jadranin, Milka and Dordević, I. and Tešević, Vele and Vajs, Vlatka and Menković, Nebojša and Soković, Marina and Glamočlija, J. and Milosavljević, Slobodan",
year = "2013",
abstract = "The composition of leaf cuticular neutral lipids of Amphoricarpos autariatus ssp. autariatus collected at canyon of river Tara (North Montenegro) was investigated by GC/MS (nonpolar fraction), LC-ESI TOF MS and 1H NMR spectroscopy (more polar fraction). The nonpolar fraction (ca. 15% of the whole surface extract) contained C27 - 33 n-alkanes, those with odd-number of carbons predominating. The LC-ESI MS and 1H NMR of the more polar fraction revealed 13 sesquiterpene lactones, constituting ca. 97.5% of the lactone mixture, identified as the known guaianolides, so-called amphoricarpolides, found previously in the aerial parts of the genus. The lactone fraction exhibited considerable in vitro effect against eight fungi, i.e. Aspergillus ochraceus, A. niger, A. versicolor, Penicillium funiculosum, P. ochrochloron, Trichoderma viride, Fusarium verticillioides and Fulvia fulvum.",
publisher = "ACG Publications",
journal = "Records of Natural Products",
title = "Sesquiterpene lactones of amphoricarpos autariatus ssp. autariatus from montenegro - Antifungal leaf - Surface constituents",
volume = "7",
number = "3",
pages = "234-238",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1360"
}
Jadranin, M., Dordević, I., Tešević, V., Vajs, V., Menković, N., Soković, M., Glamočlija, J.,& Milosavljević, S.. (2013). Sesquiterpene lactones of amphoricarpos autariatus ssp. autariatus from montenegro - Antifungal leaf - Surface constituents. in Records of Natural Products
ACG Publications., 7(3), 234-238.
https://hdl.handle.net/21.15107/rcub_cherry_1360
Jadranin M, Dordević I, Tešević V, Vajs V, Menković N, Soković M, Glamočlija J, Milosavljević S. Sesquiterpene lactones of amphoricarpos autariatus ssp. autariatus from montenegro - Antifungal leaf - Surface constituents. in Records of Natural Products. 2013;7(3):234-238.
https://hdl.handle.net/21.15107/rcub_cherry_1360 .
Jadranin, Milka, Dordević, I., Tešević, Vele, Vajs, Vlatka, Menković, Nebojša, Soković, Marina, Glamočlija, J., Milosavljević, Slobodan, "Sesquiterpene lactones of amphoricarpos autariatus ssp. autariatus from montenegro - Antifungal leaf - Surface constituents" in Records of Natural Products, 7, no. 3 (2013):234-238,
https://hdl.handle.net/21.15107/rcub_cherry_1360 .
11

Phenolic compounds, health effects and antioxidant properties of berries

Konić-Ristić, A.; Šavikin, Katarina; Zdunić, Gordana; Gođevac, Dejan; Janković, Teodora; Menković, Nebojša

(Nova Science Publishers, Inc., 2013)

TY  - CHAP
AU  - Konić-Ristić, A.
AU  - Šavikin, Katarina
AU  - Zdunić, Gordana
AU  - Gođevac, Dejan
AU  - Janković, Teodora
AU  - Menković, Nebojša
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1387
AB  - The biological value of berries relies on their nutritive and non-nutritive constituents. They are good sources of vitamins (vitamin A, C, E, folic acid), pro-vitamins and related compounds (carotene and lutein), minerals (calcium and selenium) and phytosterols, but the proposed health benefit is usually connected with phenolics as the main biologically active compound of berries. Berry phenolics include anthocyanins, flavonols, flavanols, condensed tannins (proanthocyanidins), hidrolyzable tannins (ellagitannins and gallotannins) and phenolic acids. Berries are recognized as the best dietary sources of anthocyanins. Different berries are distinguished by the presence of different classes of phenolics or compounds within the same class, their content and chemical structure (substituents, glycosylation, conjugation), potentially influencing their physiological properties and health effects. Analytical assessment of the phytochemical content of berries, the effects of storage and processing and putative interaction with other dietary compounds is essential for evaluation of their health benefit. It is of great importance to emphasize the biodiversity in the context of different phytochemical content in wild versus cultivated species, different varieties of the same species, or influenced by different cultivating conditions. Beneficial effects of berries consumption in health promotion and prevention of chronic diseases, such as cancer or cardiovascular diseases are shown in numerous epidemiological studies. In in vitro and animals studies berry fruits, their extracts and isolated compounds showed antioxidant, anticancer, antidiabetic, hypoholesterolemic, anti-inflammatory, vasoprotective, cardioprotecive, antiplatelet, antitrombotic or antimicrobial effects. Some of these effects are also shown in clinical trials in humans. Phenolic compounds of berries and their extracts have strong antioxidant potential that is often used to explain their health-promoting properties. Recent studies postulated that their antioxidant potential, as a basic mechanism of biological activity, is compromised by their low bioavailability. Consequently further research in this area is targeted towards other mechanisms of action, the evaluation of main sites of action and further elucidation of potential of berry phenolic compounds as antioxidants, based on their structure or metabolism, both in vitro and within the human body.
PB  - Nova Science Publishers, Inc.
T2  - Phytochemicals: Occurrence in Nature, Health Effects and Antioxidant Properties
T1  - Phenolic compounds, health effects and antioxidant properties of berries
SP  - 69
EP  - 85
UR  - https://hdl.handle.net/21.15107/rcub_cer_1387
ER  - 
@inbook{
author = "Konić-Ristić, A. and Šavikin, Katarina and Zdunić, Gordana and Gođevac, Dejan and Janković, Teodora and Menković, Nebojša",
year = "2013",
abstract = "The biological value of berries relies on their nutritive and non-nutritive constituents. They are good sources of vitamins (vitamin A, C, E, folic acid), pro-vitamins and related compounds (carotene and lutein), minerals (calcium and selenium) and phytosterols, but the proposed health benefit is usually connected with phenolics as the main biologically active compound of berries. Berry phenolics include anthocyanins, flavonols, flavanols, condensed tannins (proanthocyanidins), hidrolyzable tannins (ellagitannins and gallotannins) and phenolic acids. Berries are recognized as the best dietary sources of anthocyanins. Different berries are distinguished by the presence of different classes of phenolics or compounds within the same class, their content and chemical structure (substituents, glycosylation, conjugation), potentially influencing their physiological properties and health effects. Analytical assessment of the phytochemical content of berries, the effects of storage and processing and putative interaction with other dietary compounds is essential for evaluation of their health benefit. It is of great importance to emphasize the biodiversity in the context of different phytochemical content in wild versus cultivated species, different varieties of the same species, or influenced by different cultivating conditions. Beneficial effects of berries consumption in health promotion and prevention of chronic diseases, such as cancer or cardiovascular diseases are shown in numerous epidemiological studies. In in vitro and animals studies berry fruits, their extracts and isolated compounds showed antioxidant, anticancer, antidiabetic, hypoholesterolemic, anti-inflammatory, vasoprotective, cardioprotecive, antiplatelet, antitrombotic or antimicrobial effects. Some of these effects are also shown in clinical trials in humans. Phenolic compounds of berries and their extracts have strong antioxidant potential that is often used to explain their health-promoting properties. Recent studies postulated that their antioxidant potential, as a basic mechanism of biological activity, is compromised by their low bioavailability. Consequently further research in this area is targeted towards other mechanisms of action, the evaluation of main sites of action and further elucidation of potential of berry phenolic compounds as antioxidants, based on their structure or metabolism, both in vitro and within the human body.",
publisher = "Nova Science Publishers, Inc.",
journal = "Phytochemicals: Occurrence in Nature, Health Effects and Antioxidant Properties",
booktitle = "Phenolic compounds, health effects and antioxidant properties of berries",
pages = "69-85",
url = "https://hdl.handle.net/21.15107/rcub_cer_1387"
}
Konić-Ristić, A., Šavikin, K., Zdunić, G., Gođevac, D., Janković, T.,& Menković, N.. (2013). Phenolic compounds, health effects and antioxidant properties of berries. in Phytochemicals: Occurrence in Nature, Health Effects and Antioxidant Properties
Nova Science Publishers, Inc.., 69-85.
https://hdl.handle.net/21.15107/rcub_cer_1387
Konić-Ristić A, Šavikin K, Zdunić G, Gođevac D, Janković T, Menković N. Phenolic compounds, health effects and antioxidant properties of berries. in Phytochemicals: Occurrence in Nature, Health Effects and Antioxidant Properties. 2013;:69-85.
https://hdl.handle.net/21.15107/rcub_cer_1387 .
Konić-Ristić, A., Šavikin, Katarina, Zdunić, Gordana, Gođevac, Dejan, Janković, Teodora, Menković, Nebojša, "Phenolic compounds, health effects and antioxidant properties of berries" in Phytochemicals: Occurrence in Nature, Health Effects and Antioxidant Properties (2013):69-85,
https://hdl.handle.net/21.15107/rcub_cer_1387 .
1

Chemical Profile, Radical Scavenging and Cytotoxic Activity of Yellow Gentian Leaves (Genitaneae luteae folium) Grown in Northern Regions of Montenegro

Balijagic, Jasmina; Janković, Teodora; Zdunić, Gordana; Boskovic, Jelena; Savikin, Katarina; Gođevac, Dejan; Stanojković, Tatjana; Jovancevic, Miodrag; Menković, Nebojša

(Natural Products Inc, Westerville, 2012)

TY  - JOUR
AU  - Balijagic, Jasmina
AU  - Janković, Teodora
AU  - Zdunić, Gordana
AU  - Boskovic, Jelena
AU  - Savikin, Katarina
AU  - Gođevac, Dejan
AU  - Stanojković, Tatjana
AU  - Jovancevic, Miodrag
AU  - Menković, Nebojša
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1122
AB  - LC-ESI-MS and HPLC were used for the identification of the constituents from G. lutea leaves collected at different localities, as well as for quantification of the main compounds. Seven secoiridoids, five C-glucoflavones and three xanthones, were identified. Swertiamarin derivatives, namely eustornorusside (2), eustomoside (3) and septemfidoside (5), were detected in G. lutea for the first time. Concentrations of five constituents (swertiamarin, gentiopicrin, isovitexin, mangiferin and isogentisin) were determined. The relationship between concentrations of gamma-pyrones and altitude was observed with statistically significant correlation (r = 0.94). The extracts were also evaluated for their content of total phenolics, and antiradical and cytotoxic activities. The total phenolics content ranged from 7.7 to 12.7 mg GAE/g, and the IC50 values for DPPH radical scavenging activity varied between 0.45 to 2.02 mg/mL. The leaf extract exhibited moderate cytotoxic effects toward HeLa cells with an IC50 value of 41.1 mu g/mL, while gentiopicrin, mangiferin and isogentisin exerted strong activity against HeLa cells, with IC50 values ranging from 5.7 to 8.8 mu g/mL. The results confirm the traditional usage of G. lutea leaves and also suggest their possible utilization as hepatoprotective, hypoglycemic and anti-inflammatory agents.
PB  - Natural Products Inc, Westerville
T2  - Natural Product Communications
T1  - Chemical Profile, Radical Scavenging and Cytotoxic Activity of Yellow Gentian Leaves (Genitaneae luteae folium) Grown in Northern Regions of Montenegro
VL  - 7
IS  - 11
SP  - 1487
EP  - 1490
UR  - https://hdl.handle.net/21.15107/rcub_cer_1122
ER  - 
@article{
author = "Balijagic, Jasmina and Janković, Teodora and Zdunić, Gordana and Boskovic, Jelena and Savikin, Katarina and Gođevac, Dejan and Stanojković, Tatjana and Jovancevic, Miodrag and Menković, Nebojša",
year = "2012",
abstract = "LC-ESI-MS and HPLC were used for the identification of the constituents from G. lutea leaves collected at different localities, as well as for quantification of the main compounds. Seven secoiridoids, five C-glucoflavones and three xanthones, were identified. Swertiamarin derivatives, namely eustornorusside (2), eustomoside (3) and septemfidoside (5), were detected in G. lutea for the first time. Concentrations of five constituents (swertiamarin, gentiopicrin, isovitexin, mangiferin and isogentisin) were determined. The relationship between concentrations of gamma-pyrones and altitude was observed with statistically significant correlation (r = 0.94). The extracts were also evaluated for their content of total phenolics, and antiradical and cytotoxic activities. The total phenolics content ranged from 7.7 to 12.7 mg GAE/g, and the IC50 values for DPPH radical scavenging activity varied between 0.45 to 2.02 mg/mL. The leaf extract exhibited moderate cytotoxic effects toward HeLa cells with an IC50 value of 41.1 mu g/mL, while gentiopicrin, mangiferin and isogentisin exerted strong activity against HeLa cells, with IC50 values ranging from 5.7 to 8.8 mu g/mL. The results confirm the traditional usage of G. lutea leaves and also suggest their possible utilization as hepatoprotective, hypoglycemic and anti-inflammatory agents.",
publisher = "Natural Products Inc, Westerville",
journal = "Natural Product Communications",
title = "Chemical Profile, Radical Scavenging and Cytotoxic Activity of Yellow Gentian Leaves (Genitaneae luteae folium) Grown in Northern Regions of Montenegro",
volume = "7",
number = "11",
pages = "1487-1490",
url = "https://hdl.handle.net/21.15107/rcub_cer_1122"
}
Balijagic, J., Janković, T., Zdunić, G., Boskovic, J., Savikin, K., Gođevac, D., Stanojković, T., Jovancevic, M.,& Menković, N.. (2012). Chemical Profile, Radical Scavenging and Cytotoxic Activity of Yellow Gentian Leaves (Genitaneae luteae folium) Grown in Northern Regions of Montenegro. in Natural Product Communications
Natural Products Inc, Westerville., 7(11), 1487-1490.
https://hdl.handle.net/21.15107/rcub_cer_1122
Balijagic J, Janković T, Zdunić G, Boskovic J, Savikin K, Gođevac D, Stanojković T, Jovancevic M, Menković N. Chemical Profile, Radical Scavenging and Cytotoxic Activity of Yellow Gentian Leaves (Genitaneae luteae folium) Grown in Northern Regions of Montenegro. in Natural Product Communications. 2012;7(11):1487-1490.
https://hdl.handle.net/21.15107/rcub_cer_1122 .
Balijagic, Jasmina, Janković, Teodora, Zdunić, Gordana, Boskovic, Jelena, Savikin, Katarina, Gođevac, Dejan, Stanojković, Tatjana, Jovancevic, Miodrag, Menković, Nebojša, "Chemical Profile, Radical Scavenging and Cytotoxic Activity of Yellow Gentian Leaves (Genitaneae luteae folium) Grown in Northern Regions of Montenegro" in Natural Product Communications, 7, no. 11 (2012):1487-1490,
https://hdl.handle.net/21.15107/rcub_cer_1122 .
12
21

Cytotoxic and Cell Cycle Effects Induced by Two Herbal Extracts on Human Cervix Carcinoma and Human Breast Cancer Cell Lines

Stanojković, Tatjana; Konic-Ristic, Aleksandra; Juranić, Zorica; Savikin, Katarina; Zdunić, Gordana; Menković, Nebojša; Jadranin, Milka

(Mary Ann Liebert Inc, New Rochelle, 2010)

TY  - JOUR
AU  - Stanojković, Tatjana
AU  - Konic-Ristic, Aleksandra
AU  - Juranić, Zorica
AU  - Savikin, Katarina
AU  - Zdunić, Gordana
AU  - Menković, Nebojša
AU  - Jadranin, Milka
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/659
AB  - In recent times interest has increased in the complementary medicine of cancer patients. Two herbal mixtures were prepared from 17 and 12 plants, respectively. The goal of this study was to examine the in vitro cytotoxic and cell cycle effects of the aqueous-ethanol extracts (Extract 1 and Extract 2) obtained by maceration of the mixtures. The two extracts investigated exhibited significant antiproliferative activity toward two human breast cancer cell lines (MDA-MB-361 and MDA-MB-453) and a human cervix carcinoma cell line (HeLa) with 50% inhibitory concentration (IC(50)) values ranging from 9.92 to 17.38 mu L/mL. The extracts did not exert any significant cytotoxicity toward healthy human peripheral blood mononuclear cells. In vitro antitumor activites were accompanied by an important apoptotic fraction of all cell lines after treatment with the extracts. The amount of total phenols was similar in both extracts, whereas the concentration of total tannins was significantly higher in Extract 1. Extract 1 was also found to be a stronger free radical scavenger, with an IC(50) value of 13.4 mu g/mL. Both extracts contained rosmarinic acid, while ursolic acid was identified in Extract 2.
PB  - Mary Ann Liebert Inc, New Rochelle
T2  - Journal of Medicinal Food
T1  - Cytotoxic and Cell Cycle Effects Induced by Two Herbal Extracts on Human Cervix Carcinoma and Human Breast Cancer Cell Lines
VL  - 13
IS  - 2
SP  - 291
EP  - 297
DO  - 10.1089/jmf.2009.0086
ER  - 
@article{
author = "Stanojković, Tatjana and Konic-Ristic, Aleksandra and Juranić, Zorica and Savikin, Katarina and Zdunić, Gordana and Menković, Nebojša and Jadranin, Milka",
year = "2010",
abstract = "In recent times interest has increased in the complementary medicine of cancer patients. Two herbal mixtures were prepared from 17 and 12 plants, respectively. The goal of this study was to examine the in vitro cytotoxic and cell cycle effects of the aqueous-ethanol extracts (Extract 1 and Extract 2) obtained by maceration of the mixtures. The two extracts investigated exhibited significant antiproliferative activity toward two human breast cancer cell lines (MDA-MB-361 and MDA-MB-453) and a human cervix carcinoma cell line (HeLa) with 50% inhibitory concentration (IC(50)) values ranging from 9.92 to 17.38 mu L/mL. The extracts did not exert any significant cytotoxicity toward healthy human peripheral blood mononuclear cells. In vitro antitumor activites were accompanied by an important apoptotic fraction of all cell lines after treatment with the extracts. The amount of total phenols was similar in both extracts, whereas the concentration of total tannins was significantly higher in Extract 1. Extract 1 was also found to be a stronger free radical scavenger, with an IC(50) value of 13.4 mu g/mL. Both extracts contained rosmarinic acid, while ursolic acid was identified in Extract 2.",
publisher = "Mary Ann Liebert Inc, New Rochelle",
journal = "Journal of Medicinal Food",
title = "Cytotoxic and Cell Cycle Effects Induced by Two Herbal Extracts on Human Cervix Carcinoma and Human Breast Cancer Cell Lines",
volume = "13",
number = "2",
pages = "291-297",
doi = "10.1089/jmf.2009.0086"
}
Stanojković, T., Konic-Ristic, A., Juranić, Z., Savikin, K., Zdunić, G., Menković, N.,& Jadranin, M.. (2010). Cytotoxic and Cell Cycle Effects Induced by Two Herbal Extracts on Human Cervix Carcinoma and Human Breast Cancer Cell Lines. in Journal of Medicinal Food
Mary Ann Liebert Inc, New Rochelle., 13(2), 291-297.
https://doi.org/10.1089/jmf.2009.0086
Stanojković T, Konic-Ristic A, Juranić Z, Savikin K, Zdunić G, Menković N, Jadranin M. Cytotoxic and Cell Cycle Effects Induced by Two Herbal Extracts on Human Cervix Carcinoma and Human Breast Cancer Cell Lines. in Journal of Medicinal Food. 2010;13(2):291-297.
doi:10.1089/jmf.2009.0086 .
Stanojković, Tatjana, Konic-Ristic, Aleksandra, Juranić, Zorica, Savikin, Katarina, Zdunić, Gordana, Menković, Nebojša, Jadranin, Milka, "Cytotoxic and Cell Cycle Effects Induced by Two Herbal Extracts on Human Cervix Carcinoma and Human Breast Cancer Cell Lines" in Journal of Medicinal Food, 13, no. 2 (2010):291-297,
https://doi.org/10.1089/jmf.2009.0086 . .
14
10
11

Comparative analysis of parthenolide content in tanacetum larvatum, an endemic species of montenegro, collected from three different locations

Aljančić, Ivana; Vajs, Vlatka; Milosavljević, Slobodan; Todorović, Nina; Menković, Nebojša; Gođevac, Dejan; Tadić, V. M.

(Springer, New York, 2010)

TY  - JOUR
AU  - Aljančić, Ivana
AU  - Vajs, Vlatka
AU  - Milosavljević, Slobodan
AU  - Todorović, Nina
AU  - Menković, Nebojša
AU  - Gođevac, Dejan
AU  - Tadić, V. M.
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/683
PB  - Springer, New York
T2  - Chemistry of Natural Compounds
T1  - Comparative analysis of parthenolide content in tanacetum larvatum, an endemic species of montenegro, collected from three different locations
VL  - 46
IS  - 4
SP  - 658
EP  - 660
DO  - 10.1007/s10600-010-9706-2
ER  - 
@article{
author = "Aljančić, Ivana and Vajs, Vlatka and Milosavljević, Slobodan and Todorović, Nina and Menković, Nebojša and Gođevac, Dejan and Tadić, V. M.",
year = "2010",
publisher = "Springer, New York",
journal = "Chemistry of Natural Compounds",
title = "Comparative analysis of parthenolide content in tanacetum larvatum, an endemic species of montenegro, collected from three different locations",
volume = "46",
number = "4",
pages = "658-660",
doi = "10.1007/s10600-010-9706-2"
}
Aljančić, I., Vajs, V., Milosavljević, S., Todorović, N., Menković, N., Gođevac, D.,& Tadić, V. M.. (2010). Comparative analysis of parthenolide content in tanacetum larvatum, an endemic species of montenegro, collected from three different locations. in Chemistry of Natural Compounds
Springer, New York., 46(4), 658-660.
https://doi.org/10.1007/s10600-010-9706-2
Aljančić I, Vajs V, Milosavljević S, Todorović N, Menković N, Gođevac D, Tadić VM. Comparative analysis of parthenolide content in tanacetum larvatum, an endemic species of montenegro, collected from three different locations. in Chemistry of Natural Compounds. 2010;46(4):658-660.
doi:10.1007/s10600-010-9706-2 .
Aljančić, Ivana, Vajs, Vlatka, Milosavljević, Slobodan, Todorović, Nina, Menković, Nebojša, Gođevac, Dejan, Tadić, V. M., "Comparative analysis of parthenolide content in tanacetum larvatum, an endemic species of montenegro, collected from three different locations" in Chemistry of Natural Compounds, 46, no. 4 (2010):658-660,
https://doi.org/10.1007/s10600-010-9706-2 . .
2
1
3

Anti-inflammatory and Gastroprotective Properties of Hypericum richeri Oil Extracts

Zdunić, Gordana; Gođevac, Dejan; Milenković, Marina; Savikin, Katarina; Menković, Nebojša; Petrovic, Silvana

(Natural Product Incorporation, 2010)

TY  - JOUR
AU  - Zdunić, Gordana
AU  - Gođevac, Dejan
AU  - Milenković, Marina
AU  - Savikin, Katarina
AU  - Menković, Nebojša
AU  - Petrovic, Silvana
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/702
AB  - Oil extracts of flowering tops of Hypericum richeri Vill. prepared in three different ways were evaluated for chemical composition, and anti-inflammatory and gastroprotective activities. An HPLC method was developed for determination of two dominant flavonoids, quercetin and I3,II8-biapigenin. The carrageenan-induced rat paw edema test was used for screening the anti-inflammatory activity, while indomethacin-induced rat gastric mucosa damage test was used for evaluation of gastroprotective activity. The oil extract prepared by maceration with 96% ethanol, followed by extraction with sunflower oil by heating on a water bath, exhibited the highest anti-inflammatory (38.4 %) and gastroprotective activities (gastric damage score of 0.9). The same oil extract had the highest content of quercetin (49 mu g/mL) and I3,II8-biapigenin (60 mu g/mL). These results approve the usage of oil extracts of H. richeri as an anti-inflammatory and gastroprotective agent.
PB  - Natural Product Incorporation
T2  - Natural Product Communications
T1  - Anti-inflammatory and Gastroprotective Properties of Hypericum richeri Oil Extracts
VL  - 5
IS  - 8
SP  - 1215
EP  - 1218
UR  - https://hdl.handle.net/21.15107/rcub_cer_702
ER  - 
@article{
author = "Zdunić, Gordana and Gođevac, Dejan and Milenković, Marina and Savikin, Katarina and Menković, Nebojša and Petrovic, Silvana",
year = "2010",
abstract = "Oil extracts of flowering tops of Hypericum richeri Vill. prepared in three different ways were evaluated for chemical composition, and anti-inflammatory and gastroprotective activities. An HPLC method was developed for determination of two dominant flavonoids, quercetin and I3,II8-biapigenin. The carrageenan-induced rat paw edema test was used for screening the anti-inflammatory activity, while indomethacin-induced rat gastric mucosa damage test was used for evaluation of gastroprotective activity. The oil extract prepared by maceration with 96% ethanol, followed by extraction with sunflower oil by heating on a water bath, exhibited the highest anti-inflammatory (38.4 %) and gastroprotective activities (gastric damage score of 0.9). The same oil extract had the highest content of quercetin (49 mu g/mL) and I3,II8-biapigenin (60 mu g/mL). These results approve the usage of oil extracts of H. richeri as an anti-inflammatory and gastroprotective agent.",
publisher = "Natural Product Incorporation",
journal = "Natural Product Communications",
title = "Anti-inflammatory and Gastroprotective Properties of Hypericum richeri Oil Extracts",
volume = "5",
number = "8",
pages = "1215-1218",
url = "https://hdl.handle.net/21.15107/rcub_cer_702"
}
Zdunić, G., Gođevac, D., Milenković, M., Savikin, K., Menković, N.,& Petrovic, S.. (2010). Anti-inflammatory and Gastroprotective Properties of Hypericum richeri Oil Extracts. in Natural Product Communications
Natural Product Incorporation., 5(8), 1215-1218.
https://hdl.handle.net/21.15107/rcub_cer_702
Zdunić G, Gođevac D, Milenković M, Savikin K, Menković N, Petrovic S. Anti-inflammatory and Gastroprotective Properties of Hypericum richeri Oil Extracts. in Natural Product Communications. 2010;5(8):1215-1218.
https://hdl.handle.net/21.15107/rcub_cer_702 .
Zdunić, Gordana, Gođevac, Dejan, Milenković, Marina, Savikin, Katarina, Menković, Nebojša, Petrovic, Silvana, "Anti-inflammatory and Gastroprotective Properties of Hypericum richeri Oil Extracts" in Natural Product Communications, 5, no. 8 (2010):1215-1218,
https://hdl.handle.net/21.15107/rcub_cer_702 .
8
11

A new triterpenoid saponin from the aerial parts of Cephalaria ambrosioides

Gođevac, Dejan; Menković, Nebojša; Vujisić, Ljubodrag V.; Tešević, Vele; Vajs, Vlatka; Milosavljević, Slobodan

(Taylor & Francis Ltd, Abingdon, 2010)

TY  - JOUR
AU  - Gođevac, Dejan
AU  - Menković, Nebojša
AU  - Vujisić, Ljubodrag V.
AU  - Tešević, Vele
AU  - Vajs, Vlatka
AU  - Milosavljević, Slobodan
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/704
AB  - A new allose-containing triterpenoid saponin (1), along with a known saponin (2), were isolated from the aerial parts of Cephalaria ambrosioides. Their structures were determined by spectroscopic (2D-NMR and ESI-MS) methods. The preferred conformation of 1 was determined by the NOESY spectrum.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - A new triterpenoid saponin from the aerial parts of Cephalaria ambrosioides
VL  - 24
IS  - 14
SP  - 1307
EP  - 1312
DO  - 10.1080/14786410903230383
ER  - 
@article{
author = "Gođevac, Dejan and Menković, Nebojša and Vujisić, Ljubodrag V. and Tešević, Vele and Vajs, Vlatka and Milosavljević, Slobodan",
year = "2010",
abstract = "A new allose-containing triterpenoid saponin (1), along with a known saponin (2), were isolated from the aerial parts of Cephalaria ambrosioides. Their structures were determined by spectroscopic (2D-NMR and ESI-MS) methods. The preferred conformation of 1 was determined by the NOESY spectrum.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "A new triterpenoid saponin from the aerial parts of Cephalaria ambrosioides",
volume = "24",
number = "14",
pages = "1307-1312",
doi = "10.1080/14786410903230383"
}
Gođevac, D., Menković, N., Vujisić, L. V., Tešević, V., Vajs, V.,& Milosavljević, S.. (2010). A new triterpenoid saponin from the aerial parts of Cephalaria ambrosioides. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 24(14), 1307-1312.
https://doi.org/10.1080/14786410903230383
Gođevac D, Menković N, Vujisić LV, Tešević V, Vajs V, Milosavljević S. A new triterpenoid saponin from the aerial parts of Cephalaria ambrosioides. in Natural Product Research. 2010;24(14):1307-1312.
doi:10.1080/14786410903230383 .
Gođevac, Dejan, Menković, Nebojša, Vujisić, Ljubodrag V., Tešević, Vele, Vajs, Vlatka, Milosavljević, Slobodan, "A new triterpenoid saponin from the aerial parts of Cephalaria ambrosioides" in Natural Product Research, 24, no. 14 (2010):1307-1312,
https://doi.org/10.1080/14786410903230383 . .
8
9
8

Evaluation of Hypericum perforatum oil extracts for an antiinflammatory and gastroprotective activity in rats

Zdunić, Gordana; Gođevac, Dejan; Milenković, Marina; Vučićević, D.; Šavikin, Katarina; Menković, Nebojša; Petrović, S.

(2009)

TY  - JOUR
AU  - Zdunić, Gordana
AU  - Gođevac, Dejan
AU  - Milenković, Marina
AU  - Vučićević, D.
AU  - Šavikin, Katarina
AU  - Menković, Nebojša
AU  - Petrović, S.
PY  - 2009
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/625
AB  - Oil extracts of Hypericum perforatum L. (Oleum Hyperici) were prepared in three different ways according to the prescriptions from traditional medicine. Variability of constituents and biological activity were evaluated in the obtained oil extracts. The carrageenan-induced rat paw edema test has been used for screening the antiinflammatory activity, while the indomethacin-induced rat gastric mucosa damage test was used for evaluation of gastroprotective activity. All examined oil extracts possessed antiinflammatory and gastroprotective activity. Among them, the oil extract prepared by maceration with 96% ethanol, followed by extraction with sunflower oil by heating on a water bath (extract 2), in a dose of 1.25 mL/kg p.o., exhibited the highest antiinflammatory effect (95.24 ± 11.66%) and gastroprotective activity (gastric damage score of 0.21 ± 0.12). The same oil extract had the highest content of quercetin and I3,II8-biapigenin (129 ± 9 μg/mL and 52 ± 4 μg/mL, respectively). Quercetin and I3,II8-biapigenin exhibited antiinflammatory activity similar to those of indomethacin as well as significant gastroprotective activity. The results provide evidence for the usage of Oleum Hyperici as an anti-inflammatory and gastroprotective agent, which has been based previously only on ethnopharmacological claims. Copyright
T2  - Phytotherapy Research
T1  - Evaluation of Hypericum perforatum oil extracts for an antiinflammatory and gastroprotective activity in rats
VL  - 23
IS  - 11
SP  - 1559
EP  - 1564
DO  - 10.1002/ptr.2809
ER  - 
@article{
author = "Zdunić, Gordana and Gođevac, Dejan and Milenković, Marina and Vučićević, D. and Šavikin, Katarina and Menković, Nebojša and Petrović, S.",
year = "2009",
abstract = "Oil extracts of Hypericum perforatum L. (Oleum Hyperici) were prepared in three different ways according to the prescriptions from traditional medicine. Variability of constituents and biological activity were evaluated in the obtained oil extracts. The carrageenan-induced rat paw edema test has been used for screening the antiinflammatory activity, while the indomethacin-induced rat gastric mucosa damage test was used for evaluation of gastroprotective activity. All examined oil extracts possessed antiinflammatory and gastroprotective activity. Among them, the oil extract prepared by maceration with 96% ethanol, followed by extraction with sunflower oil by heating on a water bath (extract 2), in a dose of 1.25 mL/kg p.o., exhibited the highest antiinflammatory effect (95.24 ± 11.66%) and gastroprotective activity (gastric damage score of 0.21 ± 0.12). The same oil extract had the highest content of quercetin and I3,II8-biapigenin (129 ± 9 μg/mL and 52 ± 4 μg/mL, respectively). Quercetin and I3,II8-biapigenin exhibited antiinflammatory activity similar to those of indomethacin as well as significant gastroprotective activity. The results provide evidence for the usage of Oleum Hyperici as an anti-inflammatory and gastroprotective agent, which has been based previously only on ethnopharmacological claims. Copyright",
journal = "Phytotherapy Research",
title = "Evaluation of Hypericum perforatum oil extracts for an antiinflammatory and gastroprotective activity in rats",
volume = "23",
number = "11",
pages = "1559-1564",
doi = "10.1002/ptr.2809"
}
Zdunić, G., Gođevac, D., Milenković, M., Vučićević, D., Šavikin, K., Menković, N.,& Petrović, S.. (2009). Evaluation of Hypericum perforatum oil extracts for an antiinflammatory and gastroprotective activity in rats. in Phytotherapy Research, 23(11), 1559-1564.
https://doi.org/10.1002/ptr.2809
Zdunić G, Gođevac D, Milenković M, Vučićević D, Šavikin K, Menković N, Petrović S. Evaluation of Hypericum perforatum oil extracts for an antiinflammatory and gastroprotective activity in rats. in Phytotherapy Research. 2009;23(11):1559-1564.
doi:10.1002/ptr.2809 .
Zdunić, Gordana, Gođevac, Dejan, Milenković, Marina, Vučićević, D., Šavikin, Katarina, Menković, Nebojša, Petrović, S., "Evaluation of Hypericum perforatum oil extracts for an antiinflammatory and gastroprotective activity in rats" in Phytotherapy Research, 23, no. 11 (2009):1559-1564,
https://doi.org/10.1002/ptr.2809 . .
1
39
33
44

Chemical composition and antimicrobial activity of essential oil of physocaulis nodosus (L.) W.D.J.Koch

Menković, Nebojša; Šavikin, Katarina; Zdunić, Gordana; Gojgić-Cvijović, Gordana

(2009)

TY  - JOUR
AU  - Menković, Nebojša
AU  - Šavikin, Katarina
AU  - Zdunić, Gordana
AU  - Gojgić-Cvijović, Gordana
PY  - 2009
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/598
AB  - Aerial parts of Physocaulis nodosus (L.) W.D.J.Koch. (Apiaceae) collected on Hajla mountain possessed an essential oil in 0.62% yield (expressed in g per 100 g of dried plant material). The oil was analyzed by GC and GC/MS. Among 21 compounds 16 were identified, representing 93.0% of total oil composition. Dominant compounds were sabinene (36.4%), limonene (27.7%) and β-pinene (9.8%). The oil possessed a limited antibacterial activity against Micrococcus luteus, Staphylococcus aureus and Bacillus subtilis.
T2  - Journal of Essential Oil Research
T1  - Chemical composition and antimicrobial activity of essential oil of physocaulis nodosus (L.) W.D.J.Koch
VL  - 21
IS  - 1
SP  - 89
EP  - 90
DO  - 10.1080/10412905.2009.9700119
ER  - 
@article{
author = "Menković, Nebojša and Šavikin, Katarina and Zdunić, Gordana and Gojgić-Cvijović, Gordana",
year = "2009",
abstract = "Aerial parts of Physocaulis nodosus (L.) W.D.J.Koch. (Apiaceae) collected on Hajla mountain possessed an essential oil in 0.62% yield (expressed in g per 100 g of dried plant material). The oil was analyzed by GC and GC/MS. Among 21 compounds 16 were identified, representing 93.0% of total oil composition. Dominant compounds were sabinene (36.4%), limonene (27.7%) and β-pinene (9.8%). The oil possessed a limited antibacterial activity against Micrococcus luteus, Staphylococcus aureus and Bacillus subtilis.",
journal = "Journal of Essential Oil Research",
title = "Chemical composition and antimicrobial activity of essential oil of physocaulis nodosus (L.) W.D.J.Koch",
volume = "21",
number = "1",
pages = "89-90",
doi = "10.1080/10412905.2009.9700119"
}
Menković, N., Šavikin, K., Zdunić, G.,& Gojgić-Cvijović, G.. (2009). Chemical composition and antimicrobial activity of essential oil of physocaulis nodosus (L.) W.D.J.Koch. in Journal of Essential Oil Research, 21(1), 89-90.
https://doi.org/10.1080/10412905.2009.9700119
Menković N, Šavikin K, Zdunić G, Gojgić-Cvijović G. Chemical composition and antimicrobial activity of essential oil of physocaulis nodosus (L.) W.D.J.Koch. in Journal of Essential Oil Research. 2009;21(1):89-90.
doi:10.1080/10412905.2009.9700119 .
Menković, Nebojša, Šavikin, Katarina, Zdunić, Gordana, Gojgić-Cvijović, Gordana, "Chemical composition and antimicrobial activity of essential oil of physocaulis nodosus (L.) W.D.J.Koch" in Journal of Essential Oil Research, 21, no. 1 (2009):89-90,
https://doi.org/10.1080/10412905.2009.9700119 . .
8
6
10

Antioxidant activity of nine Fabaceae species growing in Serbia and Montenegro

Gođevac, Dejan; Zdunić, Gordana; Savikin, Katarina; Vajs, Vlatka; Menković, Nebojša

(Elsevier, 2008)

TY  - JOUR
AU  - Gođevac, Dejan
AU  - Zdunić, Gordana
AU  - Savikin, Katarina
AU  - Vajs, Vlatka
AU  - Menković, Nebojša
PY  - 2008
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/406
AB  - The aim of this study was to investigate antioxidant capacity of nine Fabaceae species collected on the mountains of Serbia and Montenegro. Antioxidant assays with various reaction mechanisms were used, including total phenolic content by Folin-Ciocalteu, DPPH radical scavenging capacity, Trolox equivalent antioxidant capacity (TEAC) values by ABTS radical cation and inhibition of liposome peroxidation. The investigated plants exhibited strong antioxidant capacity in all the tested methods, and among them, Lathyrus binatus, Trifolium pannonicum, and Anthyllis aurea were found to be the most active.
PB  - Elsevier
T2  - Fitoterapia
T1  - Antioxidant activity of nine Fabaceae species growing in Serbia and Montenegro
VL  - 79
IS  - 3
SP  - 185
EP  - 187
DO  - 10.1016/j.fitote.2007.10.001
ER  - 
@article{
author = "Gođevac, Dejan and Zdunić, Gordana and Savikin, Katarina and Vajs, Vlatka and Menković, Nebojša",
year = "2008",
abstract = "The aim of this study was to investigate antioxidant capacity of nine Fabaceae species collected on the mountains of Serbia and Montenegro. Antioxidant assays with various reaction mechanisms were used, including total phenolic content by Folin-Ciocalteu, DPPH radical scavenging capacity, Trolox equivalent antioxidant capacity (TEAC) values by ABTS radical cation and inhibition of liposome peroxidation. The investigated plants exhibited strong antioxidant capacity in all the tested methods, and among them, Lathyrus binatus, Trifolium pannonicum, and Anthyllis aurea were found to be the most active.",
publisher = "Elsevier",
journal = "Fitoterapia",
title = "Antioxidant activity of nine Fabaceae species growing in Serbia and Montenegro",
volume = "79",
number = "3",
pages = "185-187",
doi = "10.1016/j.fitote.2007.10.001"
}
Gođevac, D., Zdunić, G., Savikin, K., Vajs, V.,& Menković, N.. (2008). Antioxidant activity of nine Fabaceae species growing in Serbia and Montenegro. in Fitoterapia
Elsevier., 79(3), 185-187.
https://doi.org/10.1016/j.fitote.2007.10.001
Gođevac D, Zdunić G, Savikin K, Vajs V, Menković N. Antioxidant activity of nine Fabaceae species growing in Serbia and Montenegro. in Fitoterapia. 2008;79(3):185-187.
doi:10.1016/j.fitote.2007.10.001 .
Gođevac, Dejan, Zdunić, Gordana, Savikin, Katarina, Vajs, Vlatka, Menković, Nebojša, "Antioxidant activity of nine Fabaceae species growing in Serbia and Montenegro" in Fitoterapia, 79, no. 3 (2008):185-187,
https://doi.org/10.1016/j.fitote.2007.10.001 . .
26
24
30

Composition of the essential oil of Ptilostemon gnaphaloides

Đorđević, Iris; Tešević, Vele; Milosavljević, Slobodan; Menković, Nebojša; Vajs, Vlatka; Jadranin, Milka; Jovanovic, A.; Đoković, Dejan

(Springer, New York, 2008)

TY  - JOUR
AU  - Đorđević, Iris
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan
AU  - Menković, Nebojša
AU  - Vajs, Vlatka
AU  - Jadranin, Milka
AU  - Jovanovic, A.
AU  - Đoković, Dejan
PY  - 2008
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/454
PB  - Springer, New York
T2  - Chemistry of Natural Compounds
T1  - Composition of the essential oil of Ptilostemon gnaphaloides
VL  - 44
IS  - 5
SP  - 668
EP  - 669
DO  - 10.1007/s10600-008-9158-0
ER  - 
@article{
author = "Đorđević, Iris and Tešević, Vele and Milosavljević, Slobodan and Menković, Nebojša and Vajs, Vlatka and Jadranin, Milka and Jovanovic, A. and Đoković, Dejan",
year = "2008",
publisher = "Springer, New York",
journal = "Chemistry of Natural Compounds",
title = "Composition of the essential oil of Ptilostemon gnaphaloides",
volume = "44",
number = "5",
pages = "668-669",
doi = "10.1007/s10600-008-9158-0"
}
Đorđević, I., Tešević, V., Milosavljević, S., Menković, N., Vajs, V., Jadranin, M., Jovanovic, A.,& Đoković, D.. (2008). Composition of the essential oil of Ptilostemon gnaphaloides. in Chemistry of Natural Compounds
Springer, New York., 44(5), 668-669.
https://doi.org/10.1007/s10600-008-9158-0
Đorđević I, Tešević V, Milosavljević S, Menković N, Vajs V, Jadranin M, Jovanovic A, Đoković D. Composition of the essential oil of Ptilostemon gnaphaloides. in Chemistry of Natural Compounds. 2008;44(5):668-669.
doi:10.1007/s10600-008-9158-0 .
Đorđević, Iris, Tešević, Vele, Milosavljević, Slobodan, Menković, Nebojša, Vajs, Vlatka, Jadranin, Milka, Jovanovic, A., Đoković, Dejan, "Composition of the essential oil of Ptilostemon gnaphaloides" in Chemistry of Natural Compounds, 44, no. 5 (2008):668-669,
https://doi.org/10.1007/s10600-008-9158-0 . .
3
1
2

Triterpenoid saponins and iridoid glycosides from the aerial parts of Cephalaria pastricensis

Gođevac, Dejan; Mandić, Boris; Vajs, Vlatka; Tešević, Vele; Menković, Nebojša; Janaćković, Peđa T.; Milosavljević, Slobodan

(Oxford : Pergamon-Elsevier Science Ltd, 2006)

TY  - JOUR
AU  - Gođevac, Dejan
AU  - Mandić, Boris
AU  - Vajs, Vlatka
AU  - Tešević, Vele
AU  - Menković, Nebojša
AU  - Janaćković, Peđa T.
AU  - Milosavljević, Slobodan
PY  - 2006
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2716
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - Biochemical Systematics and Ecology
T1  - Triterpenoid saponins and iridoid glycosides from the aerial parts of Cephalaria pastricensis
VL  - 34
IS  - 12
SP  - 890
EP  - 893
DO  - 10.1016/j.bse.2006.05.015
ER  - 
@article{
author = "Gođevac, Dejan and Mandić, Boris and Vajs, Vlatka and Tešević, Vele and Menković, Nebojša and Janaćković, Peđa T. and Milosavljević, Slobodan",
year = "2006",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Biochemical Systematics and Ecology",
title = "Triterpenoid saponins and iridoid glycosides from the aerial parts of Cephalaria pastricensis",
volume = "34",
number = "12",
pages = "890-893",
doi = "10.1016/j.bse.2006.05.015"
}
Gođevac, D., Mandić, B., Vajs, V., Tešević, V., Menković, N., Janaćković, P. T.,& Milosavljević, S.. (2006). Triterpenoid saponins and iridoid glycosides from the aerial parts of Cephalaria pastricensis. in Biochemical Systematics and Ecology
Oxford : Pergamon-Elsevier Science Ltd., 34(12), 890-893.
https://doi.org/10.1016/j.bse.2006.05.015
Gođevac D, Mandić B, Vajs V, Tešević V, Menković N, Janaćković PT, Milosavljević S. Triterpenoid saponins and iridoid glycosides from the aerial parts of Cephalaria pastricensis. in Biochemical Systematics and Ecology. 2006;34(12):890-893.
doi:10.1016/j.bse.2006.05.015 .
Gođevac, Dejan, Mandić, Boris, Vajs, Vlatka, Tešević, Vele, Menković, Nebojša, Janaćković, Peđa T., Milosavljević, Slobodan, "Triterpenoid saponins and iridoid glycosides from the aerial parts of Cephalaria pastricensis" in Biochemical Systematics and Ecology, 34, no. 12 (2006):890-893,
https://doi.org/10.1016/j.bse.2006.05.015 . .
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