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Biocompatible microemulsions of a model NSAID for skin delivery: A decisive role of surfactants in skin penetration/irritation profiles and pharmacokinetic performance
(Elsevier, 2015)
To elaborate the decisive role of surfactants in promotion of aceclofenac' skin absorption, potentially avoiding irritation, we developed non-ionic microemulsions varying natural or synthetic surfactants: sucrose esters ...
5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII
(Oxford : Pergamon-Elsevier Science Ltd, 2015)
Inhibitory activity of a congeneric set of 23 phenyl-substituted 5-phenyl-pyrazole-3-carboxylic acids toward human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms I, II, IX and XII was evaluated by a stopped-flow CO2 hydrase ...
Influence of temperature and dopant concentration on structural, morphological and optical properties of nanometric Ce1-xErxO2-delta (x=0.05-0.20) as a pigment
(Elsevier Sci Ltd, Oxford, 2015)
Ceramic pigments based on cerium oxide were synthesized by self-propagating room temperature method and their color properties were assessed from the viewpoint of potential environmentally nontoxic pink pigments. Thermal ...
Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S
(Wiley-Blackwell, Hoboken, 2015)
Proteases are important effectors of numerous physiological and pathological processes. Reliable determination of a protease's specificity is crucial to understand protease function and to develop activity-based probes and ...
Rh catalyzed multicomponent tandem and one-pot reactions under hydroformylation conditions
(Elsevier, 2015)
The hydroformylation reaction represents one of the most important metal catalyzed bulk chemical manufacturing processes today. However, tremendous progress towards more complex molecules using tandem hydroformylation has ...
Chemo-protective and regenerative effects of diarylheptanoids from the bark of black alder (Alnus glutinosa) in human normal keratinocytes
(Elsevier, 2015)
Medicinal plants are recognized from ancient times as a source of diverse therapeutic agents and many of them are used as dietary supplements. Comprehensive approaches are needed that would identify bioactive components ...
Reactions of superoxide dismutases with HS-/H2S and superoxide radical anion: An in vitro EPR study
(Academic Press Inc Elsevier Science, San Diego, 2015)
Interactions of hydrogen sulfide (HS-/H2S), a reducing signaling species, with superoxide dimutases (SOD) are poorly understood. We applied low-T EPR spectroscopy to examine the effects of HS-/H2S and superoxide radical ...
Strong in Vitro Cytotoxic Potential of New Ruthenium-Cymene Complexes
(American Chemical Society (ACS), 2015)
Two p-cymenerutheniumchlorido complexes with thiourea derivative of 7-chloroquinoline (C1) and pyridine-3-imidazole (C2) were synthesized starting from [(eta(6)-p-cymene)RuCl2](2) and corresponding ligands. The structures ...
Characterization of sodium alginate/D-limonene emulsions and respective calcium alginate/D-limonene beads produced by electrostatic extrusion
(Elsevier Sci Ltd, Oxford, 2015)
In this study, calcium alginate beads immobilizing D-limonene (solid systems) have been manufactured starting from emulsions of this flavor in sodium alginate (liquid systems). The effects of alginate concentration (0.02 ...
Magnetic Anisotropy in "Scorpionate" First-Row Transition-Metal Complexes: A Theoretical Investigation
(Wiley-VCH Verlag Gmbh, Weinheim, 2015)
In this work we have analyzed in detail the magnetic anisotropy in a series of hydrotris(pyrazolyl)borate (Tp(-)) metal complexes, namely [VTpCl](+), [CrTpCl](+), [MnTpCl](+), [FeTpCl], [CoTpCl], and [NiTpCl], and their ...