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Synthetic route towards 1,2,3,4-tetrahydroquinoxaline/piperidine combined tricyclic ring system / Синтетски пут за добијање 1,2,3,4-тетрахидрохиноксалинскo/пиперидинског трицикличног система
(Serbian Chemical Society, 2022)
The synthetic route toward novel tricyclic, nitrogen-containing system is disclosed. Three novel compounds possessing structural features of 1,2,3,4-tetrahydroquinoxaline and decahydropyrido[3,4-b]pyrazine are synthesized ...
μ-opioid/D2 dopamine receptor pharmacophore containing ligands: Synthesis and pharmacological evaluation / Ligandi koji sadrže farmakofore za μ-opioidne i D2 dopaminske receptore: Sinteza i farmakološko ispitivanje
(Belgrade : Serbian Chemical Society, 2020)
Herein, the synthesis and pharmacological evaluation of 13 novel compounds, designed as potential heterobivalent ligands for μ-opioid receptor (MOR) and dopamine D2 receptors (D2DAR), are reported. The compounds consisted ...
Synthetic route towards potential bivalent ligands possessing opioid and D2/D3 pharmacophores / Синтетички пут за синтезу потенцијалних, бивалентних лиганада који поседују опоидну и допамин Д2/Д3 фармакогфору
(Serbian Chemical Society, 2019)
A scalable, cost-efficient and simple synthetic pathway towards potential bivalent opioid/dopamine receptor ligands was developed and optimized. Three novel compounds that contain both opioid and dopamine pharmacophores ...