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Preparation of floating polymer-valsartan delivery systems using supercritical CO2
(Springer, 2021)
This study investigates pharmaceutical polymers (Soluplus®, HPMCAS, and Eudragit® E100) and supercritical CO2-assisted process for preparation of floating valsartan delivery systems. Tested process (at pressure of 30 MPa ...
In vitro and in vivo evaluation of fluorinated indanone derivatives as potential positron emission tomography agents for the imaging of monoamine oxidase B in the brain
(Elsevier, 2021)
Monoamine oxidases (MAOs) play a key role in the metabolism of major monoamine neurotransmitters. In particular, the upregulation of MAO-B in Parkinson's disease, Alzheimer's disease and cancer augmented the development ...
Recombinant Bet v 1-BanLec chimera modulates functional characteristics of peritoneal murine macrophages by promoting IL-10 secretion
(Elsevier, 2021)
Allergen-specific immunotherapy (AIT) is a desensitizing treatment for allergic diseases that corrects the underlined pathological immune response to innocuous protein antigens, called allergens. Recombinant allergens ...
Influence of microstructure and roughness level on corrosion resistance of the austenitic stainless steel welded joint
(Wiley, 2021)
The influence of microstructure and surface roughness of the X5CrNi18-10 austenitic stainless steel-welded joint on resistance to uniform, pitting, and intergranular corrosion, as well as on the stability of the passive ...
Synthesis, characterization, antimicrobial activity and DFT study of some novel Schiff bases
(Elsevier, 2021)
Two new Schiff bases derived from L-cysteine and substituted benzaldehyde were synthesized: the compound 1 [2-((2-chlorobenzylidene) amino)-3-mercaptopropanoic acid] and the compound 2 [3-mercapto-2-((2-methoxybenzylidene) ...
Structural and thermal properties of Sn–Ag alloys
(Elsevier, 2021)
Microstructure and thermal properties of slowly cooled Sn–10% Ag and Sn–20% Ag alloys were experimentally investigated in this study. It was found that microstructure of the studied alloys is composed of large, plate-like ...
1,2,3,4-Tetrahydroisoquinoline Derivatives as a Novel Deoxyribonuclease I Inhibitors
(Wiley, 2021)
Herein we report an assessment of 24 1,2,3,4-tetrahydroisoquinoline derivatives for potential DNase I (deoxyribonuclease I) inhibitory properties in vitro. Four of them inhibited DNase I with IC50 values below 200 μM. The ...
The effect of natural modifiers for starch hydrophobization on performance of composite based on ethylene acrylic acid copolymer
(Wiley, 2021)
As a renewable resource, starch is considered to be fully biodegradable and nonpolluting to the environment but the hygroscopicity of starch is the main disadvantage for wider applicability in the production of a polymer-based ...
Stochastic method for prediction of subsidence due to the underground coal mining integrated with GIS, a case study in Serbia
(Springer Nature Switzerland AG, 2021)
The problem of subsidence and damages on buildings above mining works is an inevitable consequence of underground coal
mining in large mining basins. Significant development of various methods for prediction of the ...
Multidisciplinary research method for designing and selection of bio-inspired profiles in the conceptual designing stage
(Springer Nature Switzerland AG 2020, 2021)
A multidisciplinary research method was employed with the intention to create a series of bio-inspired flattened airfoils, observe their aerodynamic characteristics, and analyse their applicability to small devices or to ...