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Synthesis, chemical characterization, PARP inhibition, DNA binding and cellular uptake of novel ruthenium(II)-arene complexes bearing benzamide derivatives in human breast cancer cells
(Elsevier, 2020)
Inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1) showed remarkable clinical efficacy in BRCA-mutated tumors. Based on the rational drug design, derivatives of PARP inhibitor 3-aminobenzamide (3-AB), 2-amino-4-methylbenzamide ...
Valorization of walnut shell ash as a catalyst for biodiesel production
(Elsevier, 2020)
The catalytic activity of the walnut shell ash was investigated in the biodiesel production by the sunflower oil methanolysis. The catalyst was characterized by the TG-DTA, XRD, Hg porosimetry, N2 physisorption, SEM, and ...
Nickel(II) and nickel(III) Thiosemicarbazone and Hydrazone Complexes: An Unexpected Journey
(Elsevier, 2023)
In this paper, we report the synthesis, characterization, and X-ray structure analysis of one octahedral Ni(II) complex, [Ni(HL1 )2](BF4)2*H2O, formed by coordination of two ligands with NNS donor atom sets (HL1 ligand, ...
Nanocrystal dispersion of DK-I-56–1, a poorly soluble pyrazoloquinolinone positive modulator of α6 GABAA receptors: Formulation approach toward improved in vivo performance
(Elsevier, 2020)
DK-I-56–1 (7‑methoxy‑2-(4‑methoxy‑d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one), a recently developed deuterated pyrazoloquinolinone, has been recognized as a lead candidate for treatment of various neuropsychiatric ...
A Novel Route for Electrolytic Production of Very Branchy Copper Dendrites under Extreme Conditions
(IOP Publishing Limited, 2021)
Copper electrodeposition in a form of powder was examined using the pulsating overpotential (PO) regime from the sulfate electrolyte without or with an addition of various concentrations of chloride ions. Morphological and ...
Functional ibuprofen-loaded cationic nanoemulsion: Development and optimization for dry eye disease treatment
(Elsevier, 2020)
Abstract: Inflammation plays a key role in dry eye disease (DED)
affecting millions of people worldwide. Non-steroidal anti-inflammatory
drugs (NSAIDs) can be used topically to act on the inflammatory component
of DED, ...
Laccase Polyphenolic Biosensor Supported on MnO2@GNP Decorated SPCE: Preparation, Characterization, and Analytical Application
(The Electrochemical Society ("ECS")., 2021)
Based on graphene nanoplatelets capability to build block composites, as well as well-known electrochemical characteristic of the manganese oxide materials, in the present research, a nanocomposite, formed from graphene ...
NMR-based metabolomics for frauds detection and quality control of oregano samples
(Elsevier, 2021)
In this work 1H NMR metabolomics has been employed for quality control of oregano samples. NMR data and morphological analysis (MA) were combined by PCA, obtaining a model able to individuate non-marketable samples, and ...
Influence of C–H/X (X = S, Cl, N, Pt/Pd) Interactions on the Molecular and Crystal Structures of Pt(II) and Pd(II) Complexes with Thiomorpholine-4-carbonitrile: Crystallographic, Thermal, and DFT Study
(American Chemical Society (ACS), 2020)
Pt(II) and Pd(II) complexes (1 and 2, respectively) with thiomorpholine-4-carbonitrile (TM-CN), an N-substituted thiomorpholine derivative, were synthesized from tetrachlorido precursors in water. Structural analysis has ...
Field Effect and Local Gating in Nitrogen‐Terminated Nanopores (NtNP) and Nanogaps (NtNG) in Graphene
(Wiley, 2021)
Functionalization of electrodes is a wide‐used strategy in various applications ranging from single‐molecule sensing and protein sequencing, to ion trapping, to desalination. We demonstrate, employing non‐equilibrium Green′s ...