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Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism

Popović, Marko; Stevanović, Maja; Pantović Pavlović, Marijana

(Elsevier, 2024-01)

TY  - JOUR
AU  - Popović, Marko
AU  - Stevanović, Maja
AU  - Pantović Pavlović, Marijana
PY  - 2024-01
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7595
AB  - Pertussis (whooping cough) has been nearly eradicated during the 20th century, first of all due to an organized and comprehensive vaccination campaign that lasted for decades. Generations of doctors educated in Serbia (and other countries) rarely had an opportunity to see the clinical picture of pertussis. However, during 2023, the number of registered cases of pertussis in Serbia has increased several times. This is why the health authorities were forced to declare danger of an epidemic. During 2023, in Belgrade, around 1000 cases were registered. During the two months of 2024, 400 cases were registered. Some of them have ended with lethal outcome. This paper reports for the first time the biosynthesis reaction and thermodynamic properties of biosynthesis (enthalpy, entropy and Gibbs energy) of Bordetella pertussis, the cause of whooping cough. Moreover, a mechanistic model of multiplication of B. pertussis was developed. The mechanistic model was related to the pathogenesis of pertussis.
PB  - Elsevier
T2  - Microbial Risk Analysis
T1  - Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism
VL  - 26
SP  - 100292
DO  - 10.1016/j.mran.2024.100292
ER  - 
@article{
author = "Popović, Marko and Stevanović, Maja and Pantović Pavlović, Marijana",
year = "2024-01",
abstract = "Pertussis (whooping cough) has been nearly eradicated during the 20th century, first of all due to an organized and comprehensive vaccination campaign that lasted for decades. Generations of doctors educated in Serbia (and other countries) rarely had an opportunity to see the clinical picture of pertussis. However, during 2023, the number of registered cases of pertussis in Serbia has increased several times. This is why the health authorities were forced to declare danger of an epidemic. During 2023, in Belgrade, around 1000 cases were registered. During the two months of 2024, 400 cases were registered. Some of them have ended with lethal outcome. This paper reports for the first time the biosynthesis reaction and thermodynamic properties of biosynthesis (enthalpy, entropy and Gibbs energy) of Bordetella pertussis, the cause of whooping cough. Moreover, a mechanistic model of multiplication of B. pertussis was developed. The mechanistic model was related to the pathogenesis of pertussis.",
publisher = "Elsevier",
journal = "Microbial Risk Analysis",
title = "Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism",
volume = "26",
pages = "100292",
doi = "10.1016/j.mran.2024.100292"
}
Popović, M., Stevanović, M.,& Pantović Pavlović, M.. (2024-01). Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism. in Microbial Risk Analysis
Elsevier., 26, 100292.
https://doi.org/10.1016/j.mran.2024.100292
Popović M, Stevanović M, Pantović Pavlović M. Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism. in Microbial Risk Analysis. 2024;26:100292.
doi:10.1016/j.mran.2024.100292 .
Popović, Marko, Stevanović, Maja, Pantović Pavlović, Marijana, "Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism" in Microbial Risk Analysis, 26 (2024-01):100292,
https://doi.org/10.1016/j.mran.2024.100292 . .
3

All-dielectric optical metasurfaces as platforms for sensing different analytes with identical real parts of refractive index

Obradov, Marko; Jakšić, Zoran; Mladenović, Ivana; Rašljić, Milena; Vasiljević-Radović, Dana

(Springer, 2024)

TY  - JOUR
AU  - Obradov, Marko
AU  - Jakšić, Zoran
AU  - Mladenović, Ivana
AU  - Rašljić, Milena
AU  - Vasiljević-Radović, Dana
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7602
AB  - Metasurfaces are currently among the most attractive research fields, in no small measure due to their usability as refractometric sensors, offering unparalleled sensitivity up to sensing single atoms or molecules. This is rooted in their ability to localize electromagnetic fields in volumes orders of magnitude below the diffraction limit. Numerous materials, both conductive (metals, transparent conductive oxides, graphene, MXenes…) and all-dielectric (oxides, low-loss semiconductors) can be used to build them, thus tailoring metasurfaces, imparting multifunctionalities and enhancing design freedom. However, the fundamental sensing mechanism is practically identical across refractometric platforms – spectral dispersion changes of scattering parameters due to a difference between the real parts of refractive index of the analyte and the environment. Here we describe the use of exceptional capabilities of metasurfaces in transforming optical space to recognize analytes with identical real parts of refractive index but different imaginary parts. We consider a metasurface biosensor with cruciform openings array in an ultrathin silicon layer on silica. We simulate variations of the imaginary part of the effective refractive index in the openings while keeping the real part constant. The circular power flow that increases the optical path, field localization and intrinsically low losses in the optical range jointly cause that adding even the minuscule amounts of analyte with slightly increased optical absorption significantly reduces transmission through the structure, despite its exceptionally low thickness. The described principle can be used to distinguish bio-analytes with identical real part of refractive index like RNA, DNA, proteins, lipids, but also non-biological analytes.
PB  - Springer
T2  - Optical and Quantum Electronics
T1  - All-dielectric optical metasurfaces as platforms for sensing different analytes with identical real parts of refractive index
VL  - 56
SP  - 1077
DO  - 10.1007/s11082-024-07034-x
ER  - 
@article{
author = "Obradov, Marko and Jakšić, Zoran and Mladenović, Ivana and Rašljić, Milena and Vasiljević-Radović, Dana",
year = "2024",
abstract = "Metasurfaces are currently among the most attractive research fields, in no small measure due to their usability as refractometric sensors, offering unparalleled sensitivity up to sensing single atoms or molecules. This is rooted in their ability to localize electromagnetic fields in volumes orders of magnitude below the diffraction limit. Numerous materials, both conductive (metals, transparent conductive oxides, graphene, MXenes…) and all-dielectric (oxides, low-loss semiconductors) can be used to build them, thus tailoring metasurfaces, imparting multifunctionalities and enhancing design freedom. However, the fundamental sensing mechanism is practically identical across refractometric platforms – spectral dispersion changes of scattering parameters due to a difference between the real parts of refractive index of the analyte and the environment. Here we describe the use of exceptional capabilities of metasurfaces in transforming optical space to recognize analytes with identical real parts of refractive index but different imaginary parts. We consider a metasurface biosensor with cruciform openings array in an ultrathin silicon layer on silica. We simulate variations of the imaginary part of the effective refractive index in the openings while keeping the real part constant. The circular power flow that increases the optical path, field localization and intrinsically low losses in the optical range jointly cause that adding even the minuscule amounts of analyte with slightly increased optical absorption significantly reduces transmission through the structure, despite its exceptionally low thickness. The described principle can be used to distinguish bio-analytes with identical real part of refractive index like RNA, DNA, proteins, lipids, but also non-biological analytes.",
publisher = "Springer",
journal = "Optical and Quantum Electronics",
title = "All-dielectric optical metasurfaces as platforms for sensing different analytes with identical real parts of refractive index",
volume = "56",
pages = "1077",
doi = "10.1007/s11082-024-07034-x"
}
Obradov, M., Jakšić, Z., Mladenović, I., Rašljić, M.,& Vasiljević-Radović, D.. (2024). All-dielectric optical metasurfaces as platforms for sensing different analytes with identical real parts of refractive index. in Optical and Quantum Electronics
Springer., 56, 1077.
https://doi.org/10.1007/s11082-024-07034-x
Obradov M, Jakšić Z, Mladenović I, Rašljić M, Vasiljević-Radović D. All-dielectric optical metasurfaces as platforms for sensing different analytes with identical real parts of refractive index. in Optical and Quantum Electronics. 2024;56:1077.
doi:10.1007/s11082-024-07034-x .
Obradov, Marko, Jakšić, Zoran, Mladenović, Ivana, Rašljić, Milena, Vasiljević-Radović, Dana, "All-dielectric optical metasurfaces as platforms for sensing different analytes with identical real parts of refractive index" in Optical and Quantum Electronics, 56 (2024):1077,
https://doi.org/10.1007/s11082-024-07034-x . .

Unsaturated polyester resin based composites: A case study of lignin valorisation

Salah Adeen Embirsh, Hifa; Vuksanović, Marija M.; Mladenović, Ivana O.; Knežević, Nataša; Milošević, Milena; Mijatov, Slavko; Jančić-Heinemann, Radmila; Marinković, Aleksandar

(Elsevier, 2024)

TY  - GEN
AU  - Salah Adeen Embirsh, Hifa
AU  - Vuksanović, Marija M.
AU  - Mladenović, Ivana O.
AU  - Knežević, Nataša
AU  - Milošević, Milena
AU  - Mijatov, Slavko
AU  - Jančić-Heinemann, Radmila
AU  - Marinković, Aleksandar
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7601
AB  - Materials from green resources boast a low carbon footprint, forming the foundation of
 the circular economy approach in materials science. Thus, in this study, waste poly(ethylene
terephthalate) (PET) was subjected to depolymerization using propylene glycol (PG), and
subsequent polycondensation with bio-based maleic anhydride (MA) produced unsaturated
 polyester resin (b-UPR). Bio-derived acryloyl-modified Kraft lignin (KfL-A) served as a vinyl
 reactive filler in the b-UPR matrix to create b-UPR/KfL-A composites. The structural
characterization of KfL-A and b-UPR involved the use of FTIR and NMR techniques. The
 mechanical properties of the newly fabricated composites were assessed through tensile strength,
 Vickers microhardness, and dynamic mechanical tests. The addition of KfL-A to the rigid b-UPR
 matrix enhanced material flexibility, resulting in less stiff and hard materials while preserving
 composite toughness. For instance, incorporating 10 wt.% of KfL-A in b-UPR led to a 17%
 reduction in hardness, a 48% decrease in tensile strength, and a 20% reduction in toughness.
 Positive environmental impact was achieved by incorporation of 64 wt.% of renewable and
 recycled raw material. Analogously prepared b-UPR/KfL composites showed structural
 inhomogeneity and somewhat better mechanical properties. Transmission (TEM) and scanning
(SEM) electron microscopies revealed a suitable relationship between mechanical and structural
 properties of composites in relation to the extent of KfL-A addition. The UL94V flammability
 rating confirmed that flame resistance increased proportionally with the KfL-A addition. Once
 deposited in a landfill, these composites are expected to disintegrate more easily than PET, causing less harm to the environment and contributing to sustainability in the plastics cycle.
PB  - Elsevier
T2  - Chemosphere
T1  - Unsaturated polyester resin based composites: A case study of lignin valorisation
SP  - 142144
DO  - 10.1016/j.chemosphere.2024.142144.
ER  - 
@misc{
author = "Salah Adeen Embirsh, Hifa and Vuksanović, Marija M. and Mladenović, Ivana O. and Knežević, Nataša and Milošević, Milena and Mijatov, Slavko and Jančić-Heinemann, Radmila and Marinković, Aleksandar",
year = "2024",
abstract = "Materials from green resources boast a low carbon footprint, forming the foundation of
 the circular economy approach in materials science. Thus, in this study, waste poly(ethylene
terephthalate) (PET) was subjected to depolymerization using propylene glycol (PG), and
subsequent polycondensation with bio-based maleic anhydride (MA) produced unsaturated
 polyester resin (b-UPR). Bio-derived acryloyl-modified Kraft lignin (KfL-A) served as a vinyl
 reactive filler in the b-UPR matrix to create b-UPR/KfL-A composites. The structural
characterization of KfL-A and b-UPR involved the use of FTIR and NMR techniques. The
 mechanical properties of the newly fabricated composites were assessed through tensile strength,
 Vickers microhardness, and dynamic mechanical tests. The addition of KfL-A to the rigid b-UPR
 matrix enhanced material flexibility, resulting in less stiff and hard materials while preserving
 composite toughness. For instance, incorporating 10 wt.% of KfL-A in b-UPR led to a 17%
 reduction in hardness, a 48% decrease in tensile strength, and a 20% reduction in toughness.
 Positive environmental impact was achieved by incorporation of 64 wt.% of renewable and
 recycled raw material. Analogously prepared b-UPR/KfL composites showed structural
 inhomogeneity and somewhat better mechanical properties. Transmission (TEM) and scanning
(SEM) electron microscopies revealed a suitable relationship between mechanical and structural
 properties of composites in relation to the extent of KfL-A addition. The UL94V flammability
 rating confirmed that flame resistance increased proportionally with the KfL-A addition. Once
 deposited in a landfill, these composites are expected to disintegrate more easily than PET, causing less harm to the environment and contributing to sustainability in the plastics cycle.",
publisher = "Elsevier",
journal = "Chemosphere",
title = "Unsaturated polyester resin based composites: A case study of lignin valorisation",
pages = "142144",
doi = "10.1016/j.chemosphere.2024.142144."
}
Salah Adeen Embirsh, H., Vuksanović, M. M., Mladenović, I. O., Knežević, N., Milošević, M., Mijatov, S., Jančić-Heinemann, R.,& Marinković, A.. (2024). Unsaturated polyester resin based composites: A case study of lignin valorisation. in Chemosphere
Elsevier., 142144.
https://doi.org/10.1016/j.chemosphere.2024.142144.
Salah Adeen Embirsh H, Vuksanović MM, Mladenović IO, Knežević N, Milošević M, Mijatov S, Jančić-Heinemann R, Marinković A. Unsaturated polyester resin based composites: A case study of lignin valorisation. in Chemosphere. 2024;:142144.
doi:10.1016/j.chemosphere.2024.142144. .
Salah Adeen Embirsh, Hifa, Vuksanović, Marija M., Mladenović, Ivana O., Knežević, Nataša, Milošević, Milena, Mijatov, Slavko, Jančić-Heinemann, Radmila, Marinković, Aleksandar, "Unsaturated polyester resin based composites: A case study of lignin valorisation" in Chemosphere (2024):142144,
https://doi.org/10.1016/j.chemosphere.2024.142144. . .

Powder bed fusion–laser beam (PBF-LB) three-dimensional (3D) printing: Influence of laser hatching distance on the properties of zolpidem tartrate tablets

Adamov, Ivana; Stanojević, Gordana; Pavlović, Stefan; Medarević, Đorđe; Ivković, Branka; Kočović, David; Ibrić, Svetlana

(Elsevier, 2024)

TY  - GEN
AU  - Adamov, Ivana
AU  - Stanojević, Gordana
AU  - Pavlović, Stefan
AU  - Medarević, Đorđe
AU  - Ivković, Branka
AU  - Kočović, David
AU  - Ibrić, Svetlana
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7600
AB  - Laser sintering, known as powder bed fusion–laser beam (PBF-LB), offers promising potential for the fabrication of patient-specific drugs. The aim of this study was to provide an insight into the PBF-LB process with regard to the process parameters, in particular the laser hatching distance, and its influence on the properties of zolpidem tartrate (ZT) tablets. PHARMACOAT® 603 was used as the polymer, while Candurin® Gold Sheen and AEROSIL® 200 were added to facilitate 3D printing. The particle size distribution of the powder blend showed that the layer height should be set to 100 µm, while the laser hatching distance was varied in five different steps (50, 100, 150, 200 and 250 µm), keeping the temperature and laser scanning speed constant. Increasing the laser hatching distance and decreasing the laser energy input led to a decrease in the colour intensity, mass, density and hardness of the ZT tablets, while the disintegration and dissolution rate were faster due to the more fragile bonds between the particles. The laser hatching distance also influenced the ZT dosage, indicating the importance of this process parameter in the production of presonalized drugs. The absence of drug-polymer interactions and the amorphization of the ZT were confirmed.
PB  - Elsevier
T2  - International Journal of Pharmaceutics
T1  - Powder bed fusion–laser beam (PBF-LB) three-dimensional (3D) printing: Influence of laser hatching distance on the properties of zolpidem tartrate tablets
VL  - 657
SP  - 124161
DO  - 10.1016/j.ijpharm.2024.124161
ER  - 
@misc{
author = "Adamov, Ivana and Stanojević, Gordana and Pavlović, Stefan and Medarević, Đorđe and Ivković, Branka and Kočović, David and Ibrić, Svetlana",
year = "2024",
abstract = "Laser sintering, known as powder bed fusion–laser beam (PBF-LB), offers promising potential for the fabrication of patient-specific drugs. The aim of this study was to provide an insight into the PBF-LB process with regard to the process parameters, in particular the laser hatching distance, and its influence on the properties of zolpidem tartrate (ZT) tablets. PHARMACOAT® 603 was used as the polymer, while Candurin® Gold Sheen and AEROSIL® 200 were added to facilitate 3D printing. The particle size distribution of the powder blend showed that the layer height should be set to 100 µm, while the laser hatching distance was varied in five different steps (50, 100, 150, 200 and 250 µm), keeping the temperature and laser scanning speed constant. Increasing the laser hatching distance and decreasing the laser energy input led to a decrease in the colour intensity, mass, density and hardness of the ZT tablets, while the disintegration and dissolution rate were faster due to the more fragile bonds between the particles. The laser hatching distance also influenced the ZT dosage, indicating the importance of this process parameter in the production of presonalized drugs. The absence of drug-polymer interactions and the amorphization of the ZT were confirmed.",
publisher = "Elsevier",
journal = "International Journal of Pharmaceutics",
title = "Powder bed fusion–laser beam (PBF-LB) three-dimensional (3D) printing: Influence of laser hatching distance on the properties of zolpidem tartrate tablets",
volume = "657",
pages = "124161",
doi = "10.1016/j.ijpharm.2024.124161"
}
Adamov, I., Stanojević, G., Pavlović, S., Medarević, Đ., Ivković, B., Kočović, D.,& Ibrić, S.. (2024). Powder bed fusion–laser beam (PBF-LB) three-dimensional (3D) printing: Influence of laser hatching distance on the properties of zolpidem tartrate tablets. in International Journal of Pharmaceutics
Elsevier., 657, 124161.
https://doi.org/10.1016/j.ijpharm.2024.124161
Adamov I, Stanojević G, Pavlović S, Medarević Đ, Ivković B, Kočović D, Ibrić S. Powder bed fusion–laser beam (PBF-LB) three-dimensional (3D) printing: Influence of laser hatching distance on the properties of zolpidem tartrate tablets. in International Journal of Pharmaceutics. 2024;657:124161.
doi:10.1016/j.ijpharm.2024.124161 .
Adamov, Ivana, Stanojević, Gordana, Pavlović, Stefan, Medarević, Đorđe, Ivković, Branka, Kočović, David, Ibrić, Svetlana, "Powder bed fusion–laser beam (PBF-LB) three-dimensional (3D) printing: Influence of laser hatching distance on the properties of zolpidem tartrate tablets" in International Journal of Pharmaceutics, 657 (2024):124161,
https://doi.org/10.1016/j.ijpharm.2024.124161 . .

Industrial-scale bioremediation of a hydrocarbon-contaminated aquifer’s sediment at the location of a heating plant, Belgrade, Serbia

Lukić, Marija; Avdalović, Jelena; Gojgić-Cvijović, Gordana; Žerađanin, Aleksandra; Mrazovac Kurilić, Sanja; Ilić, Mila; Miletić, Srđan; Vrvić, Miroslav; Beškoski, Vladimir

(Springer Link, 2024)

TY  - JOUR
AU  - Lukić, Marija
AU  - Avdalović, Jelena
AU  - Gojgić-Cvijović, Gordana
AU  - Žerađanin, Aleksandra
AU  - Mrazovac Kurilić, Sanja
AU  - Ilić, Mila
AU  - Miletić, Srđan
AU  - Vrvić, Miroslav
AU  - Beškoski, Vladimir
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7584
AB  - The aim of this paper is to provide insight into research and activities of in situ remediation to remove petroleum hydrocarbon pollutants from a contaminated aquifer’s sediment, located near two radial collector wells of a water supply system. It was decided that the most appropriate method for remediation of this aquifer’s sediment is in situ bioremediation because it is clean, efficient and sustainable technology. Before the start of the bioremediation process, it was necessary to isolate and cultivate the microorganisms present at the contamination site, so they could be later applied in the bioremediation process. The samples before and after the bioremediation were studied using both GC and GC × GC–MS to determine how the concentrations of contaminants changed over time. Additionally, in this paper, a spatiotemporal representation of the change in hydrocarbon content by depth within the zone of the highest contamination over time is shown. After 12 months of bioremediation, the hydrocarbon content in the samples decreased by 82.0%, and based on GCxGC-MS analysis, the order of degradation of various hydrocarbon groups was as follows: steranes (99.6%), isoprenoids (98.4%), benzene derivatives (98.4%), alkanes (97.2%), and terpenes (49.3%). The exponential decay model showed the greatest decomposition rate of hydrocarbons occurred at depths of 8–10 m, with an average decay constant of 0.227, independent of the initial concentration of hydrocarbons. To the best of our knowledge, to date, the described approach has not been applied to an aquifer (the simultaneous treatment of groundwater and its associated sediment layers).
PB  - Springer Link
T2  - Clean Technologies and Environmental Policy
T1  - Industrial-scale bioremediation of a hydrocarbon-contaminated aquifer’s sediment at the location of a heating plant, Belgrade, Serbia
DO  - 10.1007/s10098-023-02724-8
ER  - 
@article{
author = "Lukić, Marija and Avdalović, Jelena and Gojgić-Cvijović, Gordana and Žerađanin, Aleksandra and Mrazovac Kurilić, Sanja and Ilić, Mila and Miletić, Srđan and Vrvić, Miroslav and Beškoski, Vladimir",
year = "2024",
abstract = "The aim of this paper is to provide insight into research and activities of in situ remediation to remove petroleum hydrocarbon pollutants from a contaminated aquifer’s sediment, located near two radial collector wells of a water supply system. It was decided that the most appropriate method for remediation of this aquifer’s sediment is in situ bioremediation because it is clean, efficient and sustainable technology. Before the start of the bioremediation process, it was necessary to isolate and cultivate the microorganisms present at the contamination site, so they could be later applied in the bioremediation process. The samples before and after the bioremediation were studied using both GC and GC × GC–MS to determine how the concentrations of contaminants changed over time. Additionally, in this paper, a spatiotemporal representation of the change in hydrocarbon content by depth within the zone of the highest contamination over time is shown. After 12 months of bioremediation, the hydrocarbon content in the samples decreased by 82.0%, and based on GCxGC-MS analysis, the order of degradation of various hydrocarbon groups was as follows: steranes (99.6%), isoprenoids (98.4%), benzene derivatives (98.4%), alkanes (97.2%), and terpenes (49.3%). The exponential decay model showed the greatest decomposition rate of hydrocarbons occurred at depths of 8–10 m, with an average decay constant of 0.227, independent of the initial concentration of hydrocarbons. To the best of our knowledge, to date, the described approach has not been applied to an aquifer (the simultaneous treatment of groundwater and its associated sediment layers).",
publisher = "Springer Link",
journal = "Clean Technologies and Environmental Policy",
title = "Industrial-scale bioremediation of a hydrocarbon-contaminated aquifer’s sediment at the location of a heating plant, Belgrade, Serbia",
doi = "10.1007/s10098-023-02724-8"
}
Lukić, M., Avdalović, J., Gojgić-Cvijović, G., Žerađanin, A., Mrazovac Kurilić, S., Ilić, M., Miletić, S., Vrvić, M.,& Beškoski, V.. (2024). Industrial-scale bioremediation of a hydrocarbon-contaminated aquifer’s sediment at the location of a heating plant, Belgrade, Serbia. in Clean Technologies and Environmental Policy
Springer Link..
https://doi.org/10.1007/s10098-023-02724-8
Lukić M, Avdalović J, Gojgić-Cvijović G, Žerađanin A, Mrazovac Kurilić S, Ilić M, Miletić S, Vrvić M, Beškoski V. Industrial-scale bioremediation of a hydrocarbon-contaminated aquifer’s sediment at the location of a heating plant, Belgrade, Serbia. in Clean Technologies and Environmental Policy. 2024;.
doi:10.1007/s10098-023-02724-8 .
Lukić, Marija, Avdalović, Jelena, Gojgić-Cvijović, Gordana, Žerađanin, Aleksandra, Mrazovac Kurilić, Sanja, Ilić, Mila, Miletić, Srđan, Vrvić, Miroslav, Beškoski, Vladimir, "Industrial-scale bioremediation of a hydrocarbon-contaminated aquifer’s sediment at the location of a heating plant, Belgrade, Serbia" in Clean Technologies and Environmental Policy (2024),
https://doi.org/10.1007/s10098-023-02724-8 . .
1

Probing the potential of mercury removal by covalently immobilized phycobiliproteins onto the surface of chitosan beads

Radović, Jelena; Popović, Dragana; Ćurčić, Tatjana; Veličković, Luka; Lević, Steva; Pavlović, Vladimir; Minić, Simeon; Nikolić, Milan; Gligorijević, Nikola

(Elsevier, 2024)

TY  - JOUR
AU  - Radović, Jelena
AU  - Popović, Dragana
AU  - Ćurčić, Tatjana
AU  - Veličković, Luka
AU  - Lević, Steva
AU  - Pavlović, Vladimir
AU  - Minić, Simeon
AU  - Nikolić, Milan
AU  - Gligorijević, Nikola
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7596
AB  - Mercury emissions represent a significant risk to the environment and human health. Mercury is persistent and
can circulate in the environment for thousands of years, which is why treating this toxic metal is important.
Chitosan polymer is easily obtainable, and it has good mercury adsorption characteristics. This study aimed to
improve its capabilities to absorb mercury by immobilizing phycobiliproteins (PBPs) onto the surface of chitosan
beads (chitosan–PBPs). Phycobiliproteins, light-harvesting proteins from algae and cyanobacteria, have several
industrially essential applications. These proteins can bind heavy metals with high affinities. Protein extracts
obtained from both Arthrospira platensis, with C-phycocyanin (C-PC) as the primary protein, and Porphyra
yezoensis, with R-phycocyanin (R-PC) and R-phycoerythrin (R-PE) as the dominant PBPs, were covalently
immobilized onto chitosan beads. Beads with immobilized PBPs were characterized by scanning electron microscopy
and Fourier transform infrared spectroscopy. Binding analysis showed that, on average, each chitosan
bead weighed 20 mg and immobilized 63.54 μg of PBPs from Spirulina and 44.12 μg of PBPs from Porphyra.
Immobilized proteins were still in their native state, with no visible color change months after immobilization.
Chitosan–PBPs and chitosan alone were tested for mercury adsorption at pH 4 and pH 7 by atomic absorption
spectroscopy. The tested concentration range of mercury was from 1 to 70 ppm. Affinity, calculated using
Henry’s binding isotherm, of chitosan–PBPs for mercury was twice as much higher at both pH values than
chitosan alone. Furthermore, chitosan-PBP beads were able to absorb more mercury than chitosan alone. These
results showed that the covalent immobilization of PBPs onto chitosan improves its mercury adsorption characteristics
and creates a more efficient eco-friendly adsorbent to potentially remove mercury ions in the tested
concentration range from polluted waters.
PB  - Elsevier
T2  - Algal Research
T1  - Probing the potential of mercury removal by covalently immobilized phycobiliproteins onto the surface of chitosan beads
VL  - 80
SP  - 103543
DO  - 10.1016/j.algal.2024.103543
ER  - 
@article{
author = "Radović, Jelena and Popović, Dragana and Ćurčić, Tatjana and Veličković, Luka and Lević, Steva and Pavlović, Vladimir and Minić, Simeon and Nikolić, Milan and Gligorijević, Nikola",
year = "2024",
abstract = "Mercury emissions represent a significant risk to the environment and human health. Mercury is persistent and
can circulate in the environment for thousands of years, which is why treating this toxic metal is important.
Chitosan polymer is easily obtainable, and it has good mercury adsorption characteristics. This study aimed to
improve its capabilities to absorb mercury by immobilizing phycobiliproteins (PBPs) onto the surface of chitosan
beads (chitosan–PBPs). Phycobiliproteins, light-harvesting proteins from algae and cyanobacteria, have several
industrially essential applications. These proteins can bind heavy metals with high affinities. Protein extracts
obtained from both Arthrospira platensis, with C-phycocyanin (C-PC) as the primary protein, and Porphyra
yezoensis, with R-phycocyanin (R-PC) and R-phycoerythrin (R-PE) as the dominant PBPs, were covalently
immobilized onto chitosan beads. Beads with immobilized PBPs were characterized by scanning electron microscopy
and Fourier transform infrared spectroscopy. Binding analysis showed that, on average, each chitosan
bead weighed 20 mg and immobilized 63.54 μg of PBPs from Spirulina and 44.12 μg of PBPs from Porphyra.
Immobilized proteins were still in their native state, with no visible color change months after immobilization.
Chitosan–PBPs and chitosan alone were tested for mercury adsorption at pH 4 and pH 7 by atomic absorption
spectroscopy. The tested concentration range of mercury was from 1 to 70 ppm. Affinity, calculated using
Henry’s binding isotherm, of chitosan–PBPs for mercury was twice as much higher at both pH values than
chitosan alone. Furthermore, chitosan-PBP beads were able to absorb more mercury than chitosan alone. These
results showed that the covalent immobilization of PBPs onto chitosan improves its mercury adsorption characteristics
and creates a more efficient eco-friendly adsorbent to potentially remove mercury ions in the tested
concentration range from polluted waters.",
publisher = "Elsevier",
journal = "Algal Research",
title = "Probing the potential of mercury removal by covalently immobilized phycobiliproteins onto the surface of chitosan beads",
volume = "80",
pages = "103543",
doi = "10.1016/j.algal.2024.103543"
}
Radović, J., Popović, D., Ćurčić, T., Veličković, L., Lević, S., Pavlović, V., Minić, S., Nikolić, M.,& Gligorijević, N.. (2024). Probing the potential of mercury removal by covalently immobilized phycobiliproteins onto the surface of chitosan beads. in Algal Research
Elsevier., 80, 103543.
https://doi.org/10.1016/j.algal.2024.103543
Radović J, Popović D, Ćurčić T, Veličković L, Lević S, Pavlović V, Minić S, Nikolić M, Gligorijević N. Probing the potential of mercury removal by covalently immobilized phycobiliproteins onto the surface of chitosan beads. in Algal Research. 2024;80:103543.
doi:10.1016/j.algal.2024.103543 .
Radović, Jelena, Popović, Dragana, Ćurčić, Tatjana, Veličković, Luka, Lević, Steva, Pavlović, Vladimir, Minić, Simeon, Nikolić, Milan, Gligorijević, Nikola, "Probing the potential of mercury removal by covalently immobilized phycobiliproteins onto the surface of chitosan beads" in Algal Research, 80 (2024):103543,
https://doi.org/10.1016/j.algal.2024.103543 . .

Glycosylation and Characterization of Human Transferrin in an End-Stage Kidney Disease

Miljuš, Goran; Penezić, Ana; Pažitná, Lucia; Gligorijević, Nikola; Baralić, Marko; Vilotić, Aleksandra; Šunderić, Miloš; Robajac, Dragana; Dobrijević, Zorana; Katrlík, Jaroslav; Nedić, Olgica

(Multidisciplinary Digital Publishing Institute (MDPI), 2024)

TY  - JOUR
AU  - Miljuš, Goran
AU  - Penezić, Ana
AU  - Pažitná, Lucia
AU  - Gligorijević, Nikola
AU  - Baralić, Marko
AU  - Vilotić, Aleksandra
AU  - Šunderić, Miloš
AU  - Robajac, Dragana
AU  - Dobrijević, Zorana
AU  - Katrlík, Jaroslav
AU  - Nedić, Olgica
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7597
AB  - Chronic kidney disease (CKD) is a global health concern affecting approximately one billion individuals worldwide. End-stage kidney disease (ESKD), the most severe form of CKD, is
often accompanied by anemia. Peritoneal dialysis (PD), a common treatment for ESKD, utilizes the
peritoneum for solute transfer but is associated with complications including protein loss, including
transferrin (Tf) a key protein involved in iron transport. This study investigated Tf characteristics in
ESKD patients compared to healthy individuals using lectin microarray, spectroscopic techniques and immunocytochemical analysis to assess Tf interaction with transferrin receptors (TfRs). ESKD patients exhibited altered Tf glycosylation patterns, evidenced by significant changes in lectin reactivity compared to healthy controls. However, structural analyses revealed no significant differences in the Tf secondary or tertiary structures between the two groups. A functional analysis demonstrated comparable Tf-TfR interaction in both PD and healthy samples. Despite significant alterations in Tf glycosylation, structural integrity and Tf-TfR interaction remained preserved in PD patients. These findings suggest that while glycosylation changes may influence iron metabolism, they do not impair Tf function. The study highlights the importance of a glucose-free dialysis solutions in managing anemia exacerbation in PD patients with poorly controlled anemia, potentially offering a targeted therapeutic approach to improve patient outcomes.
PB  - Multidisciplinary Digital Publishing Institute (MDPI)
T2  - International Journal of Molecular Sciences
T1  - Glycosylation and Characterization of Human Transferrin in an End-Stage Kidney Disease
VL  - 25
IS  - 9
SP  - 4625
DO  - 10.3390/ijms25094625
ER  - 
@article{
author = "Miljuš, Goran and Penezić, Ana and Pažitná, Lucia and Gligorijević, Nikola and Baralić, Marko and Vilotić, Aleksandra and Šunderić, Miloš and Robajac, Dragana and Dobrijević, Zorana and Katrlík, Jaroslav and Nedić, Olgica",
year = "2024",
abstract = "Chronic kidney disease (CKD) is a global health concern affecting approximately one billion individuals worldwide. End-stage kidney disease (ESKD), the most severe form of CKD, is
often accompanied by anemia. Peritoneal dialysis (PD), a common treatment for ESKD, utilizes the
peritoneum for solute transfer but is associated with complications including protein loss, including
transferrin (Tf) a key protein involved in iron transport. This study investigated Tf characteristics in
ESKD patients compared to healthy individuals using lectin microarray, spectroscopic techniques and immunocytochemical analysis to assess Tf interaction with transferrin receptors (TfRs). ESKD patients exhibited altered Tf glycosylation patterns, evidenced by significant changes in lectin reactivity compared to healthy controls. However, structural analyses revealed no significant differences in the Tf secondary or tertiary structures between the two groups. A functional analysis demonstrated comparable Tf-TfR interaction in both PD and healthy samples. Despite significant alterations in Tf glycosylation, structural integrity and Tf-TfR interaction remained preserved in PD patients. These findings suggest that while glycosylation changes may influence iron metabolism, they do not impair Tf function. The study highlights the importance of a glucose-free dialysis solutions in managing anemia exacerbation in PD patients with poorly controlled anemia, potentially offering a targeted therapeutic approach to improve patient outcomes.",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
journal = "International Journal of Molecular Sciences",
title = "Glycosylation and Characterization of Human Transferrin in an End-Stage Kidney Disease",
volume = "25",
number = "9",
pages = "4625",
doi = "10.3390/ijms25094625"
}
Miljuš, G., Penezić, A., Pažitná, L., Gligorijević, N., Baralić, M., Vilotić, A., Šunderić, M., Robajac, D., Dobrijević, Z., Katrlík, J.,& Nedić, O.. (2024). Glycosylation and Characterization of Human Transferrin in an End-Stage Kidney Disease. in International Journal of Molecular Sciences
Multidisciplinary Digital Publishing Institute (MDPI)., 25(9), 4625.
https://doi.org/10.3390/ijms25094625
Miljuš G, Penezić A, Pažitná L, Gligorijević N, Baralić M, Vilotić A, Šunderić M, Robajac D, Dobrijević Z, Katrlík J, Nedić O. Glycosylation and Characterization of Human Transferrin in an End-Stage Kidney Disease. in International Journal of Molecular Sciences. 2024;25(9):4625.
doi:10.3390/ijms25094625 .
Miljuš, Goran, Penezić, Ana, Pažitná, Lucia, Gligorijević, Nikola, Baralić, Marko, Vilotić, Aleksandra, Šunderić, Miloš, Robajac, Dragana, Dobrijević, Zorana, Katrlík, Jaroslav, Nedić, Olgica, "Glycosylation and Characterization of Human Transferrin in an End-Stage Kidney Disease" in International Journal of Molecular Sciences, 25, no. 9 (2024):4625,
https://doi.org/10.3390/ijms25094625 . .

Boosting Institute of Chemistry, Technology and Metallurgy in water biomonitoring - BIOLAWEB

Vidaković, Danijela; Avdalović, Jelena; Dojčinović, Biljana; Marković, Aleksandra; Miletić, Srđan; Milanović, Katarina; Milovanović, Željka; Petrović, Vladimir; Zlatović, Dragana; Alric, Benjamin; Dumont, Herve; Lemonnier, Clarisse; Moatti, Antoine; Rimet, Frederic; Ballot, Andreas; Claudia Schneider, Susanne; Ćirić, Miloš

(Savez hemijskih inženjera Srbije, 2024)

TY  - CONF
AU  - Vidaković, Danijela
AU  - Avdalović, Jelena
AU  - Dojčinović, Biljana
AU  - Marković, Aleksandra
AU  - Miletić, Srđan
AU  - Milanović, Katarina
AU  - Milovanović, Željka
AU  - Petrović, Vladimir
AU  - Zlatović, Dragana
AU  - Alric, Benjamin
AU  - Dumont, Herve
AU  - Lemonnier, Clarisse
AU  - Moatti, Antoine
AU  - Rimet, Frederic
AU  - Ballot, Andreas
AU  - Claudia Schneider, Susanne
AU  - Ćirić, Miloš
PY  - 2024
UR  - https://www.ache-pub.org.rs/index.php/HemInd/article/view/1324
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7594
AB  - Project "Boosting Institute of Chemistry, Technology and Metallurgy in Water Biomonitoring" (BIOLAWEB) aims to strengthen the research and innovation capacity of the Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade (UB-ICTM) in biodiversity assessment and biomonitoring. UB-ICTM researchers made a noticeable contribution to the study of biodiversity, community ecology, and conservation of water bodies in South-Eastern Europe. However, a knowledge on index development and intercalibration following the EU standards for lakes and watercourse monitoring is still lacking in this geographic region. Similarly, there is a knowledge gap in DNA-based ecological status assessment in SEE.
PB  - Savez hemijskih inženjera Srbije
C3  - Hemijska industrija
T1  - Boosting Institute of Chemistry, Technology and Metallurgy in water biomonitoring - BIOLAWEB
VL  - 78
IS  - 1s
SP  - 77
UR  - https://hdl.handle.net/21.15107/rcub_cer_7594
ER  - 
@conference{
author = "Vidaković, Danijela and Avdalović, Jelena and Dojčinović, Biljana and Marković, Aleksandra and Miletić, Srđan and Milanović, Katarina and Milovanović, Željka and Petrović, Vladimir and Zlatović, Dragana and Alric, Benjamin and Dumont, Herve and Lemonnier, Clarisse and Moatti, Antoine and Rimet, Frederic and Ballot, Andreas and Claudia Schneider, Susanne and Ćirić, Miloš",
year = "2024",
abstract = "Project "Boosting Institute of Chemistry, Technology and Metallurgy in Water Biomonitoring" (BIOLAWEB) aims to strengthen the research and innovation capacity of the Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade (UB-ICTM) in biodiversity assessment and biomonitoring. UB-ICTM researchers made a noticeable contribution to the study of biodiversity, community ecology, and conservation of water bodies in South-Eastern Europe. However, a knowledge on index development and intercalibration following the EU standards for lakes and watercourse monitoring is still lacking in this geographic region. Similarly, there is a knowledge gap in DNA-based ecological status assessment in SEE.",
publisher = "Savez hemijskih inženjera Srbije",
journal = "Hemijska industrija",
title = "Boosting Institute of Chemistry, Technology and Metallurgy in water biomonitoring - BIOLAWEB",
volume = "78",
number = "1s",
pages = "77",
url = "https://hdl.handle.net/21.15107/rcub_cer_7594"
}
Vidaković, D., Avdalović, J., Dojčinović, B., Marković, A., Miletić, S., Milanović, K., Milovanović, Ž., Petrović, V., Zlatović, D., Alric, B., Dumont, H., Lemonnier, C., Moatti, A., Rimet, F., Ballot, A., Claudia Schneider, S.,& Ćirić, M.. (2024). Boosting Institute of Chemistry, Technology and Metallurgy in water biomonitoring - BIOLAWEB. in Hemijska industrija
Savez hemijskih inženjera Srbije., 78(1s), 77.
https://hdl.handle.net/21.15107/rcub_cer_7594
Vidaković D, Avdalović J, Dojčinović B, Marković A, Miletić S, Milanović K, Milovanović Ž, Petrović V, Zlatović D, Alric B, Dumont H, Lemonnier C, Moatti A, Rimet F, Ballot A, Claudia Schneider S, Ćirić M. Boosting Institute of Chemistry, Technology and Metallurgy in water biomonitoring - BIOLAWEB. in Hemijska industrija. 2024;78(1s):77.
https://hdl.handle.net/21.15107/rcub_cer_7594 .
Vidaković, Danijela, Avdalović, Jelena, Dojčinović, Biljana, Marković, Aleksandra, Miletić, Srđan, Milanović, Katarina, Milovanović, Željka, Petrović, Vladimir, Zlatović, Dragana, Alric, Benjamin, Dumont, Herve, Lemonnier, Clarisse, Moatti, Antoine, Rimet, Frederic, Ballot, Andreas, Claudia Schneider, Susanne, Ćirić, Miloš, "Boosting Institute of Chemistry, Technology and Metallurgy in water biomonitoring - BIOLAWEB" in Hemijska industrija, 78, no. 1s (2024):77,
https://hdl.handle.net/21.15107/rcub_cer_7594 .

Promising in vitro and in silico biological activity of tetradentate Schiff base copper(II) complexes with a propylenediamine bridge

Mijatović, Aleksandar; Šeba, Tino; Gligorijević, Nevenka; Ćoćić, Dušan; Spasić, Snežana; Lolić, Aleksandar; Aranđelović, Sandra; Nikolić, Milan; Gabričević, Mario; Baošić, Rada

(Royal Society of Chemistry, 2024)

TY  - JOUR
AU  - Mijatović, Aleksandar
AU  - Šeba, Tino
AU  - Gligorijević, Nevenka
AU  - Ćoćić, Dušan
AU  - Spasić, Snežana
AU  - Lolić, Aleksandar
AU  - Aranđelović, Sandra
AU  - Nikolić, Milan
AU  - Gabričević, Mario
AU  - Baošić, Rada
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7593
AB  - The molecular structures of six neutral copper(II) complexes with propylenediamine bridges and different terminal groups have been reported and evaluated. Different antioxidant tests were performed on these complexes. Additionally, the antibacterial and antifungal activities of the investigated compounds were assessed. The study was complemented with data on their interaction with human serum albumin (HSA) and evaluated using spectroscopic fluorescence techniques. The copper(II) complexes were found to bind to HSA at multiple sites (n = 0.82–1.72), displaying relatively high binding constants on the order of Ka = (4.8–8.8) × 104 M−1. Furthermore, binding constants calculated from microscale thermophoresis (MST) data were within the range of 1.27 × 104–1.13 × 105 M−1; these results correlated well with the above Ka values obtained by fluorimetry. Molecular docking simulations were employed to study the ability of the complexes to bind to target macromolecules, such as HSA and DNA. As a significant addition to understanding their biological behavior, an MTT assay was performed to investigate the cytotoxicity of the complexes. The antiproliferative activity of the investigated copper(II) complexes with propylenediamine ligands, along with cisplatin as a reference compound, was evaluated in two human cancer cell lines (LS-174 and MCF-7) and one normal cell line (MRC-5). The obtained results are discussed, providing the structure–activity relationship of the copper(II) complexes with Schiff base tetradentate ligands.
PB  - Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - Promising in vitro and in silico biological activity of tetradentate Schiff base copper(II) complexes with a propylenediamine bridge
VL  - 48
IS  - 13
SP  - 5959
DO  - 10.1039/D3NJ05270B
ER  - 
@article{
author = "Mijatović, Aleksandar and Šeba, Tino and Gligorijević, Nevenka and Ćoćić, Dušan and Spasić, Snežana and Lolić, Aleksandar and Aranđelović, Sandra and Nikolić, Milan and Gabričević, Mario and Baošić, Rada",
year = "2024",
abstract = "The molecular structures of six neutral copper(II) complexes with propylenediamine bridges and different terminal groups have been reported and evaluated. Different antioxidant tests were performed on these complexes. Additionally, the antibacterial and antifungal activities of the investigated compounds were assessed. The study was complemented with data on their interaction with human serum albumin (HSA) and evaluated using spectroscopic fluorescence techniques. The copper(II) complexes were found to bind to HSA at multiple sites (n = 0.82–1.72), displaying relatively high binding constants on the order of Ka = (4.8–8.8) × 104 M−1. Furthermore, binding constants calculated from microscale thermophoresis (MST) data were within the range of 1.27 × 104–1.13 × 105 M−1; these results correlated well with the above Ka values obtained by fluorimetry. Molecular docking simulations were employed to study the ability of the complexes to bind to target macromolecules, such as HSA and DNA. As a significant addition to understanding their biological behavior, an MTT assay was performed to investigate the cytotoxicity of the complexes. The antiproliferative activity of the investigated copper(II) complexes with propylenediamine ligands, along with cisplatin as a reference compound, was evaluated in two human cancer cell lines (LS-174 and MCF-7) and one normal cell line (MRC-5). The obtained results are discussed, providing the structure–activity relationship of the copper(II) complexes with Schiff base tetradentate ligands.",
publisher = "Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "Promising in vitro and in silico biological activity of tetradentate Schiff base copper(II) complexes with a propylenediamine bridge",
volume = "48",
number = "13",
pages = "5959",
doi = "10.1039/D3NJ05270B"
}
Mijatović, A., Šeba, T., Gligorijević, N., Ćoćić, D., Spasić, S., Lolić, A., Aranđelović, S., Nikolić, M., Gabričević, M.,& Baošić, R.. (2024). Promising in vitro and in silico biological activity of tetradentate Schiff base copper(II) complexes with a propylenediamine bridge. in New Journal of Chemistry
Royal Society of Chemistry., 48(13), 5959.
https://doi.org/10.1039/D3NJ05270B
Mijatović A, Šeba T, Gligorijević N, Ćoćić D, Spasić S, Lolić A, Aranđelović S, Nikolić M, Gabričević M, Baošić R. Promising in vitro and in silico biological activity of tetradentate Schiff base copper(II) complexes with a propylenediamine bridge. in New Journal of Chemistry. 2024;48(13):5959.
doi:10.1039/D3NJ05270B .
Mijatović, Aleksandar, Šeba, Tino, Gligorijević, Nevenka, Ćoćić, Dušan, Spasić, Snežana, Lolić, Aleksandar, Aranđelović, Sandra, Nikolić, Milan, Gabričević, Mario, Baošić, Rada, "Promising in vitro and in silico biological activity of tetradentate Schiff base copper(II) complexes with a propylenediamine bridge" in New Journal of Chemistry, 48, no. 13 (2024):5959,
https://doi.org/10.1039/D3NJ05270B . .

Comparison of photometric methods for detecting film forming amines in water and progress in study of their interaction with surface oxides

Vidojković, Sonja; Lindeboom, Ralph; Mijajlovic, Miroslav

(The International Association for the Properties of Water and Steam, 2024)

TY  - CONF
AU  - Vidojković, Sonja
AU  - Lindeboom, Ralph
AU  - Mijajlovic, Miroslav
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7587
AB  - This paper discusses and compares the sensitivity, accuracy, selectivity, impeding factors, and other characteristics of various photometric methods for determining the concentration of film forming amines. It enables the selection of the appropriate analytical method based on the type of FFA, water composition, required sensitivity, accuracy, and other criteria.
Additionally, a brief overview of progress in investigating the interaction of FFA with surface oxides is provided.
PB  - The International Association for the Properties of Water and Steam
C3  - IAPWS 7th International Conference on Film Forming Substances (FFS2024), March 26-28, 2024, Prato, Italy
T1  - Comparison of photometric methods for detecting film forming amines in water and progress in study of their interaction with surface oxides
UR  - https://hdl.handle.net/21.15107/rcub_cer_7587
ER  - 
@conference{
author = "Vidojković, Sonja and Lindeboom, Ralph and Mijajlovic, Miroslav",
year = "2024",
abstract = "This paper discusses and compares the sensitivity, accuracy, selectivity, impeding factors, and other characteristics of various photometric methods for determining the concentration of film forming amines. It enables the selection of the appropriate analytical method based on the type of FFA, water composition, required sensitivity, accuracy, and other criteria.
Additionally, a brief overview of progress in investigating the interaction of FFA with surface oxides is provided.",
publisher = "The International Association for the Properties of Water and Steam",
journal = "IAPWS 7th International Conference on Film Forming Substances (FFS2024), March 26-28, 2024, Prato, Italy",
title = "Comparison of photometric methods for detecting film forming amines in water and progress in study of their interaction with surface oxides",
url = "https://hdl.handle.net/21.15107/rcub_cer_7587"
}
Vidojković, S., Lindeboom, R.,& Mijajlovic, M.. (2024). Comparison of photometric methods for detecting film forming amines in water and progress in study of their interaction with surface oxides. in IAPWS 7th International Conference on Film Forming Substances (FFS2024), March 26-28, 2024, Prato, Italy
The International Association for the Properties of Water and Steam..
https://hdl.handle.net/21.15107/rcub_cer_7587
Vidojković S, Lindeboom R, Mijajlovic M. Comparison of photometric methods for detecting film forming amines in water and progress in study of their interaction with surface oxides. in IAPWS 7th International Conference on Film Forming Substances (FFS2024), March 26-28, 2024, Prato, Italy. 2024;.
https://hdl.handle.net/21.15107/rcub_cer_7587 .
Vidojković, Sonja, Lindeboom, Ralph, Mijajlovic, Miroslav, "Comparison of photometric methods for detecting film forming amines in water and progress in study of their interaction with surface oxides" in IAPWS 7th International Conference on Film Forming Substances (FFS2024), March 26-28, 2024, Prato, Italy (2024),
https://hdl.handle.net/21.15107/rcub_cer_7587 .

Stokholmska konvencija: Regulisanje upotrebe dugotrajnih organskih zagađivača u cilju očuvanja životne sredine i zdravlja ljudi

Milić, Jelena

(2024)

TY  - GEN
AU  - Milić, Jelena
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7591
AB  - Stokholmska konvencija, usvojena 2001. godine, predstavlja ključni međunarodni instrument za regulisanje upotrebe dugotrajnih organskih zagađivača (POPs) s ciljem zaštite životne sredine i zdravlja ljudi. Ova konvencija postavlja stroge standarde za kontrolu proizvodnje, upotrebe i ispuštanja POPs-a, poput dioksina, furana i pesticida kao što je DDT. Cilj konvencije je eliminacija i smanjenje izloženosti ovim opasnim supstancama koje se mogu akumulirati u životnoj sredini i naneti štetu ljudskom zdravlju i ekosistemima. Implementacija Stokholmske konvencije zahteva globalnu saradnju i koordinaciju kako bi se postigao dugoročni cilj očuvanja životne sredine i zaštite zdravlja ljudi širom sveta. Visoko obrazovanje igra ključnu ulogu u ostvarivanju ciljeva Stokholmske konvencije kroz edukaciju budućih naučnika i stručnjaka koji će biti angažovani u oblastima vezanim za zaštitu životne sredine i smanjenje upotrebe POPs hemikalija. Kroz relevantne kurseve, istraživačke projekte i praktična iskustva, studenti mogu steći razumevanje kompleksnosti problema vezanih za POPs, kao i veštine potrebne za njihovo rešavanje.
T1  - Stokholmska konvencija: Regulisanje upotrebe dugotrajnih organskih zagađivača u cilju očuvanja životne sredine i zdravlja ljudi
UR  - https://hdl.handle.net/21.15107/rcub_cer_7591
ER  - 
@misc{
author = "Milić, Jelena",
year = "2024",
abstract = "Stokholmska konvencija, usvojena 2001. godine, predstavlja ključni međunarodni instrument za regulisanje upotrebe dugotrajnih organskih zagađivača (POPs) s ciljem zaštite životne sredine i zdravlja ljudi. Ova konvencija postavlja stroge standarde za kontrolu proizvodnje, upotrebe i ispuštanja POPs-a, poput dioksina, furana i pesticida kao što je DDT. Cilj konvencije je eliminacija i smanjenje izloženosti ovim opasnim supstancama koje se mogu akumulirati u životnoj sredini i naneti štetu ljudskom zdravlju i ekosistemima. Implementacija Stokholmske konvencije zahteva globalnu saradnju i koordinaciju kako bi se postigao dugoročni cilj očuvanja životne sredine i zaštite zdravlja ljudi širom sveta. Visoko obrazovanje igra ključnu ulogu u ostvarivanju ciljeva Stokholmske konvencije kroz edukaciju budućih naučnika i stručnjaka koji će biti angažovani u oblastima vezanim za zaštitu životne sredine i smanjenje upotrebe POPs hemikalija. Kroz relevantne kurseve, istraživačke projekte i praktična iskustva, studenti mogu steći razumevanje kompleksnosti problema vezanih za POPs, kao i veštine potrebne za njihovo rešavanje.",
title = "Stokholmska konvencija: Regulisanje upotrebe dugotrajnih organskih zagađivača u cilju očuvanja životne sredine i zdravlja ljudi",
url = "https://hdl.handle.net/21.15107/rcub_cer_7591"
}
Milić, J.. (2024). Stokholmska konvencija: Regulisanje upotrebe dugotrajnih organskih zagađivača u cilju očuvanja životne sredine i zdravlja ljudi. .
https://hdl.handle.net/21.15107/rcub_cer_7591
Milić J. Stokholmska konvencija: Regulisanje upotrebe dugotrajnih organskih zagađivača u cilju očuvanja životne sredine i zdravlja ljudi. 2024;.
https://hdl.handle.net/21.15107/rcub_cer_7591 .
Milić, Jelena, "Stokholmska konvencija: Regulisanje upotrebe dugotrajnih organskih zagađivača u cilju očuvanja životne sredine i zdravlja ljudi" (2024),
https://hdl.handle.net/21.15107/rcub_cer_7591 .

Development of iminosugar-based glycosidase inhibitors as drug candidates for SARS-CoV-2 virus via molecular modelling and in vitro studies

Ferjančić, Zorana; Bihelović, Filip; Vulović, Bojan; Matović, Radomir; Trmčić, Milena; Janković, Aleksandar; Pavlović, Miloš; Đurković, Filip T.; Prodanović, Radivoje; Đurđević Đelmaš, Aleksandra; Kaličanin, Nevena; Zlatović, Mario; Sladić, Dušan; Vallet, Thomas; Vignuzzi, Marco; Saičić, Radomir N.

(Taylor and Francis Group, 2024)

TY  - JOUR
AU  - Ferjančić, Zorana
AU  - Bihelović, Filip
AU  - Vulović, Bojan
AU  - Matović, Radomir
AU  - Trmčić, Milena
AU  - Janković, Aleksandar
AU  - Pavlović, Miloš
AU  - Đurković, Filip T.
AU  - Prodanović, Radivoje
AU  - Đurđević Đelmaš, Aleksandra
AU  - Kaličanin, Nevena
AU  - Zlatović, Mario
AU  - Sladić, Dušan
AU  - Vallet, Thomas
AU  - Vignuzzi, Marco
AU  - Saičić, Radomir N.
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7585
AB  - We developed new iminosugar-based glycosidase inhibitors against SARS-CoV-2. Known drugs (miglustat, migalastat, miglitol, and swainsonine) were chosen as lead compounds to develop three classes of glycosidase inhibitors (α-glucosidase, α-galactosidase, and mannosidase). Molecular modelling of the lead compounds, synthesis of the compounds with the highest docking scores, enzyme inhibition tests, and in vitro antiviral assays afforded rationally designed inhibitors. Two highly active α-glucosidase inhibitors were discovered, where one of them is the most potent iminosugar-based anti-SARS-CoV-2 agent to date (EC90 = 1.94 µM in A549-ACE2 cells against Omicron BA.1 strain). However, galactosidase inhibitors did not exhibit antiviral activity, whereas mannosidase inhibitors were both active and cytotoxic. As our iminosugar-based drug candidates act by a host-directed mechanism, they should be more resilient to drug resistance. Moreover, this strategy could be extended to identify potential drug candidates for other viral infections.
PB  - Taylor and Francis Group
T2  - Journal of Enzyme Inhibition and Medicinal Chemistry
T1  - Development of iminosugar-based glycosidase inhibitors as drug candidates for SARS-CoV-2 virus via molecular modelling and in vitro studies
VL  - 39
IS  - 1
SP  - 2289007
DO  - 10.1080/14756366.2023.2289007
ER  - 
@article{
author = "Ferjančić, Zorana and Bihelović, Filip and Vulović, Bojan and Matović, Radomir and Trmčić, Milena and Janković, Aleksandar and Pavlović, Miloš and Đurković, Filip T. and Prodanović, Radivoje and Đurđević Đelmaš, Aleksandra and Kaličanin, Nevena and Zlatović, Mario and Sladić, Dušan and Vallet, Thomas and Vignuzzi, Marco and Saičić, Radomir N.",
year = "2024",
abstract = "We developed new iminosugar-based glycosidase inhibitors against SARS-CoV-2. Known drugs (miglustat, migalastat, miglitol, and swainsonine) were chosen as lead compounds to develop three classes of glycosidase inhibitors (α-glucosidase, α-galactosidase, and mannosidase). Molecular modelling of the lead compounds, synthesis of the compounds with the highest docking scores, enzyme inhibition tests, and in vitro antiviral assays afforded rationally designed inhibitors. Two highly active α-glucosidase inhibitors were discovered, where one of them is the most potent iminosugar-based anti-SARS-CoV-2 agent to date (EC90 = 1.94 µM in A549-ACE2 cells against Omicron BA.1 strain). However, galactosidase inhibitors did not exhibit antiviral activity, whereas mannosidase inhibitors were both active and cytotoxic. As our iminosugar-based drug candidates act by a host-directed mechanism, they should be more resilient to drug resistance. Moreover, this strategy could be extended to identify potential drug candidates for other viral infections.",
publisher = "Taylor and Francis Group",
journal = "Journal of Enzyme Inhibition and Medicinal Chemistry",
title = "Development of iminosugar-based glycosidase inhibitors as drug candidates for SARS-CoV-2 virus via molecular modelling and in vitro studies",
volume = "39",
number = "1",
pages = "2289007",
doi = "10.1080/14756366.2023.2289007"
}
Ferjančić, Z., Bihelović, F., Vulović, B., Matović, R., Trmčić, M., Janković, A., Pavlović, M., Đurković, F. T., Prodanović, R., Đurđević Đelmaš, A., Kaličanin, N., Zlatović, M., Sladić, D., Vallet, T., Vignuzzi, M.,& Saičić, R. N.. (2024). Development of iminosugar-based glycosidase inhibitors as drug candidates for SARS-CoV-2 virus via molecular modelling and in vitro studies. in Journal of Enzyme Inhibition and Medicinal Chemistry
Taylor and Francis Group., 39(1), 2289007.
https://doi.org/10.1080/14756366.2023.2289007
Ferjančić Z, Bihelović F, Vulović B, Matović R, Trmčić M, Janković A, Pavlović M, Đurković FT, Prodanović R, Đurđević Đelmaš A, Kaličanin N, Zlatović M, Sladić D, Vallet T, Vignuzzi M, Saičić RN. Development of iminosugar-based glycosidase inhibitors as drug candidates for SARS-CoV-2 virus via molecular modelling and in vitro studies. in Journal of Enzyme Inhibition and Medicinal Chemistry. 2024;39(1):2289007.
doi:10.1080/14756366.2023.2289007 .
Ferjančić, Zorana, Bihelović, Filip, Vulović, Bojan, Matović, Radomir, Trmčić, Milena, Janković, Aleksandar, Pavlović, Miloš, Đurković, Filip T., Prodanović, Radivoje, Đurđević Đelmaš, Aleksandra, Kaličanin, Nevena, Zlatović, Mario, Sladić, Dušan, Vallet, Thomas, Vignuzzi, Marco, Saičić, Radomir N., "Development of iminosugar-based glycosidase inhibitors as drug candidates for SARS-CoV-2 virus via molecular modelling and in vitro studies" in Journal of Enzyme Inhibition and Medicinal Chemistry, 39, no. 1 (2024):2289007,
https://doi.org/10.1080/14756366.2023.2289007 . .
4
2
1

Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation

Trmčić, Milena; Vulović, Bojan; Zlatar, Matija; Saičić, Radomir N.

(ARKAT USA, Inc., 2024)

TY  - JOUR
AU  - Trmčić, Milena
AU  - Vulović, Bojan
AU  - Zlatar, Matija
AU  - Saičić, Radomir N.
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7041
AB  - Hemiacetals of cyclopropanone can be isolated and stocked, contrary to their highly reactive parent ketone.  However, they are not readily converted to cyclopropanone, which limits their use as its synthetic equivalents.  2,2,2-trifluoroethoxy hemiacetals are expected to be better cyclopropanone surrogates, however, they have  never been prepared, so far. We show that oxyallyl cations with a heteroatom in the -position can be  intercepted with 2,2,2-trifluoroethanol, with formation of cyclopropanone trifluoroethoxy hemiacetals stable  enough to be isolated, purified and characterized. These species can serve as synthetic equivalents of  cyclopropanone under mild conditions.
PB  - ARKAT USA, Inc.
T2  - ARKIVOC - Online Journal of Organic Chemistry
T1  - Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation
VL  - 2024
IS  - 2
DO  - 10.24820/ark.5550190.p012.123
ER  - 
@article{
author = "Trmčić, Milena and Vulović, Bojan and Zlatar, Matija and Saičić, Radomir N.",
year = "2024",
abstract = "Hemiacetals of cyclopropanone can be isolated and stocked, contrary to their highly reactive parent ketone.  However, they are not readily converted to cyclopropanone, which limits their use as its synthetic equivalents.  2,2,2-trifluoroethoxy hemiacetals are expected to be better cyclopropanone surrogates, however, they have  never been prepared, so far. We show that oxyallyl cations with a heteroatom in the -position can be  intercepted with 2,2,2-trifluoroethanol, with formation of cyclopropanone trifluoroethoxy hemiacetals stable  enough to be isolated, purified and characterized. These species can serve as synthetic equivalents of  cyclopropanone under mild conditions.",
publisher = "ARKAT USA, Inc.",
journal = "ARKIVOC - Online Journal of Organic Chemistry",
title = "Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation",
volume = "2024",
number = "2",
doi = "10.24820/ark.5550190.p012.123"
}
Trmčić, M., Vulović, B., Zlatar, M.,& Saičić, R. N.. (2024). Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation. in ARKIVOC - Online Journal of Organic Chemistry
ARKAT USA, Inc.., 2024(2).
https://doi.org/10.24820/ark.5550190.p012.123
Trmčić M, Vulović B, Zlatar M, Saičić RN. Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation. in ARKIVOC - Online Journal of Organic Chemistry. 2024;2024(2).
doi:10.24820/ark.5550190.p012.123 .
Trmčić, Milena, Vulović, Bojan, Zlatar, Matija, Saičić, Radomir N., "Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation" in ARKIVOC - Online Journal of Organic Chemistry, 2024, no. 2 (2024),
https://doi.org/10.24820/ark.5550190.p012.123 . .

Electrodeposition of copper on glassy carbon and palladium from choline chloride - ethylene glycol deep eutectic solvent

Cvetković, Vesna S.; Jović, Vladimir D.; Nikolić, Nebojša D.; Barudžija, Tanja S.; Dimitrijević, Silvana B.; Jovićević, Jovan N.

(Elsevier, 2024)

TY  - JOUR
AU  - Cvetković, Vesna S.
AU  - Jović, Vladimir D.
AU  - Nikolić, Nebojša D.
AU  - Barudžija, Tanja S.
AU  - Dimitrijević, Silvana B.
AU  - Jovićević, Jovan N.
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7572
AB  - Electrodeposition of copper from deep eutectic solvents (DES) based on a mixture of choline chloride and
ethylene glycol containing CuCl2⋅2H2O at 50 ◦C and 80 ◦C was studied. Electrochemical reduction/oxidation of
Cu(II)/Cu(0) on glassy carbon (GC) and palladium (Pd) electrodes was investigated by cyclic voltammetry (CV)
and square wave voltammetry (SWV) emphasizing that this process takes place through two steps, Cu(II) ↔ Cu(I)
and Cu(I) ↔ Cu(0). The CV results showed that in chloride-rich DES electrolytes, the increased presence of chloro
ligands raises the overpotential required for Cu electrodeposition. The electrochemical impedance spectroscopy
(EIS) results indicate simultaneous electrodeposition of Cu and electrosorption of large cations on electrodeposited
Cu on both GC and Pd substrates. Scanning electron microscopy (SEM) results showed that Cu grains of
approximately 1 μm were obtained by electrodeposition of Cu on both Pd and GC, whereby better coverage by
electrodeposited Cu was obtained on Pd than on GC. Cu electrodeposited on Pd was relatively uniform and
smooth, but porous, while Cu electrodeposited on GC was dispersed in small agglomerates. Energy-dispersive Xray
spectroscopy (EDS) of Cu electrodeposited on Pd detected the dominant presence of Cu with the possibility of
the formation of CuPd alloy. The presence of CuPd alloy face-centred cubic structures is confirmed by X-ray
diffraction (XRD) along with metallic Cu.
PB  - Elsevier
T2  - Journal of Electroanalytical Chemistry
T1  - Electrodeposition of copper on glassy carbon and palladium from choline chloride - ethylene glycol deep eutectic solvent
VL  - 958
SP  - 118161
DO  - 10.1016/j.jelechem.2024.118161
ER  - 
@article{
author = "Cvetković, Vesna S. and Jović, Vladimir D. and Nikolić, Nebojša D. and Barudžija, Tanja S. and Dimitrijević, Silvana B. and Jovićević, Jovan N.",
year = "2024",
abstract = "Electrodeposition of copper from deep eutectic solvents (DES) based on a mixture of choline chloride and
ethylene glycol containing CuCl2⋅2H2O at 50 ◦C and 80 ◦C was studied. Electrochemical reduction/oxidation of
Cu(II)/Cu(0) on glassy carbon (GC) and palladium (Pd) electrodes was investigated by cyclic voltammetry (CV)
and square wave voltammetry (SWV) emphasizing that this process takes place through two steps, Cu(II) ↔ Cu(I)
and Cu(I) ↔ Cu(0). The CV results showed that in chloride-rich DES electrolytes, the increased presence of chloro
ligands raises the overpotential required for Cu electrodeposition. The electrochemical impedance spectroscopy
(EIS) results indicate simultaneous electrodeposition of Cu and electrosorption of large cations on electrodeposited
Cu on both GC and Pd substrates. Scanning electron microscopy (SEM) results showed that Cu grains of
approximately 1 μm were obtained by electrodeposition of Cu on both Pd and GC, whereby better coverage by
electrodeposited Cu was obtained on Pd than on GC. Cu electrodeposited on Pd was relatively uniform and
smooth, but porous, while Cu electrodeposited on GC was dispersed in small agglomerates. Energy-dispersive Xray
spectroscopy (EDS) of Cu electrodeposited on Pd detected the dominant presence of Cu with the possibility of
the formation of CuPd alloy. The presence of CuPd alloy face-centred cubic structures is confirmed by X-ray
diffraction (XRD) along with metallic Cu.",
publisher = "Elsevier",
journal = "Journal of Electroanalytical Chemistry",
title = "Electrodeposition of copper on glassy carbon and palladium from choline chloride - ethylene glycol deep eutectic solvent",
volume = "958",
pages = "118161",
doi = "10.1016/j.jelechem.2024.118161"
}
Cvetković, V. S., Jović, V. D., Nikolić, N. D., Barudžija, T. S., Dimitrijević, S. B.,& Jovićević, J. N.. (2024). Electrodeposition of copper on glassy carbon and palladium from choline chloride - ethylene glycol deep eutectic solvent. in Journal of Electroanalytical Chemistry
Elsevier., 958, 118161.
https://doi.org/10.1016/j.jelechem.2024.118161
Cvetković VS, Jović VD, Nikolić ND, Barudžija TS, Dimitrijević SB, Jovićević JN. Electrodeposition of copper on glassy carbon and palladium from choline chloride - ethylene glycol deep eutectic solvent. in Journal of Electroanalytical Chemistry. 2024;958:118161.
doi:10.1016/j.jelechem.2024.118161 .
Cvetković, Vesna S., Jović, Vladimir D., Nikolić, Nebojša D., Barudžija, Tanja S., Dimitrijević, Silvana B., Jovićević, Jovan N., "Electrodeposition of copper on glassy carbon and palladium from choline chloride - ethylene glycol deep eutectic solvent" in Journal of Electroanalytical Chemistry, 958 (2024):118161,
https://doi.org/10.1016/j.jelechem.2024.118161 . .

Efficient Removal of Water Soluble Fraction of Diesel Oil by Biochar Sorption Supported by Microbiological Degradation

Lopičić, Zorica; Šoštarić, Tatjana; Milojković, Jelena; Antanasković, Anja; Milić, Jelena; Spasić, Snežana; Avdalović, Jelena

(MDPI, 2024)

TY  - JOUR
AU  - Lopičić, Zorica
AU  - Šoštarić, Tatjana
AU  - Milojković, Jelena
AU  - Antanasković, Anja
AU  - Milić, Jelena
AU  - Spasić, Snežana
AU  - Avdalović, Jelena
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7571
AB  - he contamination of the water bodies by diesel oil (DO) and its water-soluble fraction (WSF) represents one of the most challenging tasks in the management of polluted water streams. This paper contains data related to the synthesis and characteristics of the plum stone biochar material (PmS-B), which was made from waste plum stones (PmS), along with its possible application in the sorption of the WSF of DO from contaminated water. Techniques applied in sample characterisation and comparisons were: Elemental Organic Analysis (EOA), Scanning Electron Microscopy−Energy Dispersive X-ray Spectroscopy (SEM-EDX), Fourier Transform Infrared Spectroscopy (FTIR), pH (pHsus) and point of zero charge (pHpzc). In order to increase the overall efficiency of the removal process, sorption and bioremediation were subsequently combined. Firstly, PmS-B was used as a sorbent of WSF, and then the remaining solution was additionally treated with a specific consortium of microorganisms. After the first treatment phase, the initial concentration of diesel WSF was reduced by more than 90%, where most of the aromatic components of DO were removed by sorption. The sorption equilibrium results were best fitted by the Sips isotherm model, where the maximum sorption capacity was found to be 40.72 mg/g. The rest of the hydrocarbon components that remained in the solution were further subjected to the biodegradation process by a consortium of microorganisms. Microbial degradation lasted 19 days and reduced the total diesel WSF concentration to 0.46 mg/L. In order to confirm the non-toxicity of the water sample after this two-stage treatment, eco-toxicity tests based on a microbial biosensor (Aliivibrio fischeri) were applied, confirming the high efficiency of the proposed method.
PB  - MDPI
T2  - Processes
T1  - Efficient Removal of Water Soluble Fraction of Diesel Oil by Biochar Sorption Supported by Microbiological Degradation
VL  - 12
IS  - 5
SP  - 964
DO  - 10.3390/pr12050964
ER  - 
@article{
author = "Lopičić, Zorica and Šoštarić, Tatjana and Milojković, Jelena and Antanasković, Anja and Milić, Jelena and Spasić, Snežana and Avdalović, Jelena",
year = "2024",
abstract = "he contamination of the water bodies by diesel oil (DO) and its water-soluble fraction (WSF) represents one of the most challenging tasks in the management of polluted water streams. This paper contains data related to the synthesis and characteristics of the plum stone biochar material (PmS-B), which was made from waste plum stones (PmS), along with its possible application in the sorption of the WSF of DO from contaminated water. Techniques applied in sample characterisation and comparisons were: Elemental Organic Analysis (EOA), Scanning Electron Microscopy−Energy Dispersive X-ray Spectroscopy (SEM-EDX), Fourier Transform Infrared Spectroscopy (FTIR), pH (pHsus) and point of zero charge (pHpzc). In order to increase the overall efficiency of the removal process, sorption and bioremediation were subsequently combined. Firstly, PmS-B was used as a sorbent of WSF, and then the remaining solution was additionally treated with a specific consortium of microorganisms. After the first treatment phase, the initial concentration of diesel WSF was reduced by more than 90%, where most of the aromatic components of DO were removed by sorption. The sorption equilibrium results were best fitted by the Sips isotherm model, where the maximum sorption capacity was found to be 40.72 mg/g. The rest of the hydrocarbon components that remained in the solution were further subjected to the biodegradation process by a consortium of microorganisms. Microbial degradation lasted 19 days and reduced the total diesel WSF concentration to 0.46 mg/L. In order to confirm the non-toxicity of the water sample after this two-stage treatment, eco-toxicity tests based on a microbial biosensor (Aliivibrio fischeri) were applied, confirming the high efficiency of the proposed method.",
publisher = "MDPI",
journal = "Processes",
title = "Efficient Removal of Water Soluble Fraction of Diesel Oil by Biochar Sorption Supported by Microbiological Degradation",
volume = "12",
number = "5",
pages = "964",
doi = "10.3390/pr12050964"
}
Lopičić, Z., Šoštarić, T., Milojković, J., Antanasković, A., Milić, J., Spasić, S.,& Avdalović, J.. (2024). Efficient Removal of Water Soluble Fraction of Diesel Oil by Biochar Sorption Supported by Microbiological Degradation. in Processes
MDPI., 12(5), 964.
https://doi.org/10.3390/pr12050964
Lopičić Z, Šoštarić T, Milojković J, Antanasković A, Milić J, Spasić S, Avdalović J. Efficient Removal of Water Soluble Fraction of Diesel Oil by Biochar Sorption Supported by Microbiological Degradation. in Processes. 2024;12(5):964.
doi:10.3390/pr12050964 .
Lopičić, Zorica, Šoštarić, Tatjana, Milojković, Jelena, Antanasković, Anja, Milić, Jelena, Spasić, Snežana, Avdalović, Jelena, "Efficient Removal of Water Soluble Fraction of Diesel Oil by Biochar Sorption Supported by Microbiological Degradation" in Processes, 12, no. 5 (2024):964,
https://doi.org/10.3390/pr12050964 . .

Mechanical properties of laminate materials based on polylactic acid and polyvinyl chloride meshes as reinforcement

Vorkapić, Miloš; Bajić, Danica M.; Baltić, Marija; Nešić, Dušan; Mladenović, Ivana

(Belgrade, Serbia : Balkan Scientific Centre, 2024)

TY  - JOUR
AU  - Vorkapić, Miloš
AU  - Bajić, Danica M.
AU  - Baltić, Marija
AU  - Nešić, Dušan
AU  - Mladenović, Ivana
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7573
AB  - The 3D printing parameters are known to have a significant impact on manufactured
parts, and the layered morphology of these parts makes mechanical design analysis for
engineering applications difficult. In this work, the tensile strengths and microhardness
of 3D printed polylactic acid (PLA) specimens with different orientations and numbers
of individual layers of mesh material (polyvinyl chloride – PVC) were investigated as a
laminate composite. Composite specimens were obtained using 3D printing via fused
deposition modelling (FDM). Moreover, the influence of printing parameters (i.e. infill
density and layer height) and the number and orientation of reinforced meshes on the
mechanical response was investigated. Fracture strength of PLA/PVC laminate
composites ranges from 31.30 MPa (3 PVC mesh layers; mesh height position:
25 % │ 50 % │ 75 %; infill density: 60 %; PVC mesh orientation: 90° │ 45° │ 90°; layer
height: 0.2 mm) to 18.62 MPa (without PVC mesh; infill density: 30 %; layer height: 0.1
mm) demonstrating a significant impact of the number of the PVC mesh layers, infill
density of PLA and layer height on the final mechanical parameters of printing
PLA/PVC elements. The surface hardness at the micro load level showed that the
number of reinforcement layers affects the microhardness value, as well as material
filling and mesh orientation. The specimen with the following parameters gave the
best results: layer height: 0.2 mm; 3 PVC mesh layers; infill density: 60 %; PVC mesh
orientation: 90° │ 45° │ 90°. The average hardness values for one layer and three layers
of mesh were in accordance with tensile test results.
PB  - Belgrade, Serbia : Balkan Scientific Centre
T2  - Tribology and Materials
T1  - Mechanical properties of laminate materials based on polylactic acid and polyvinyl chloride meshes as reinforcement
VL  - 3
IS  - 1
SP  - 35
EP  - 43
DO  - 10.46793/tribomat.2024.005
ER  - 
@article{
author = "Vorkapić, Miloš and Bajić, Danica M. and Baltić, Marija and Nešić, Dušan and Mladenović, Ivana",
year = "2024",
abstract = "The 3D printing parameters are known to have a significant impact on manufactured
parts, and the layered morphology of these parts makes mechanical design analysis for
engineering applications difficult. In this work, the tensile strengths and microhardness
of 3D printed polylactic acid (PLA) specimens with different orientations and numbers
of individual layers of mesh material (polyvinyl chloride – PVC) were investigated as a
laminate composite. Composite specimens were obtained using 3D printing via fused
deposition modelling (FDM). Moreover, the influence of printing parameters (i.e. infill
density and layer height) and the number and orientation of reinforced meshes on the
mechanical response was investigated. Fracture strength of PLA/PVC laminate
composites ranges from 31.30 MPa (3 PVC mesh layers; mesh height position:
25 % │ 50 % │ 75 %; infill density: 60 %; PVC mesh orientation: 90° │ 45° │ 90°; layer
height: 0.2 mm) to 18.62 MPa (without PVC mesh; infill density: 30 %; layer height: 0.1
mm) demonstrating a significant impact of the number of the PVC mesh layers, infill
density of PLA and layer height on the final mechanical parameters of printing
PLA/PVC elements. The surface hardness at the micro load level showed that the
number of reinforcement layers affects the microhardness value, as well as material
filling and mesh orientation. The specimen with the following parameters gave the
best results: layer height: 0.2 mm; 3 PVC mesh layers; infill density: 60 %; PVC mesh
orientation: 90° │ 45° │ 90°. The average hardness values for one layer and three layers
of mesh were in accordance with tensile test results.",
publisher = "Belgrade, Serbia : Balkan Scientific Centre",
journal = "Tribology and Materials",
title = "Mechanical properties of laminate materials based on polylactic acid and polyvinyl chloride meshes as reinforcement",
volume = "3",
number = "1",
pages = "35-43",
doi = "10.46793/tribomat.2024.005"
}
Vorkapić, M., Bajić, D. M., Baltić, M., Nešić, D.,& Mladenović, I.. (2024). Mechanical properties of laminate materials based on polylactic acid and polyvinyl chloride meshes as reinforcement. in Tribology and Materials
Belgrade, Serbia : Balkan Scientific Centre., 3(1), 35-43.
https://doi.org/10.46793/tribomat.2024.005
Vorkapić M, Bajić DM, Baltić M, Nešić D, Mladenović I. Mechanical properties of laminate materials based on polylactic acid and polyvinyl chloride meshes as reinforcement. in Tribology and Materials. 2024;3(1):35-43.
doi:10.46793/tribomat.2024.005 .
Vorkapić, Miloš, Bajić, Danica M., Baltić, Marija, Nešić, Dušan, Mladenović, Ivana, "Mechanical properties of laminate materials based on polylactic acid and polyvinyl chloride meshes as reinforcement" in Tribology and Materials, 3, no. 1 (2024):35-43,
https://doi.org/10.46793/tribomat.2024.005 . .

Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2

Popović, Marko; Stevanović, Maja; Mihailović, Marija

(Serbian Chemical Society, 2024)

TY  - JOUR
AU  - Popović, Marko
AU  - Stevanović, Maja
AU  - Mihailović, Marija
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7559
AB  - Breaking news are usually disturbing. Natural disasters, wars, epidemics etc. are reported as breaking news. This paper reports a decreased danger of spreading of epidemics caused by the JN.1 variant, since analyses indicate that (a) infectivity of the new variant is decreased compared to most earlier variants, which is confirmed by the number of cases (7500 daily in USA). Moreover, JN.1 despite the great number of mutations has not been able to achieve the values of Gibbs energy of biosynthesis (and thus virus multiplication rate) of the Hu-1 wild type. The research shows that infectivity and pathogenicity of the JN.1 variant has not reached worrying size, which means that there is no reason to expect a worsening of the epidemiologic situation.
AB  - Ударне вести су обично узнемирујуће. О природним катастрофама, ратовима, епидемијама итд. се извештава као ударним вестима. У овом раду је приказана смањена опасност од ширења епидемија изазваних варијантом JN.1, јер анализе показују да је (а) инфективност нове варијанте смањена у односу на већину ранијих варијанти, што потврђује и број случајева (7500 дневно у САД). Штавише, JN.1 упркос великом броју мутација није успео да постигне вредности Гибсове енергије биосинтезе (а самим тим и стопе размножавања вируса) дивљег типа Hu.1. Истраживање показује да инфективност и патогеност варијанте JN.1 није достигла забрињавајућу величину, што значи да нема разлога за очекивање погоршање епидемиолошке ситуације.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2
T1  - Ударне вести: емпиријске формуле, моларне масе, реакције биосинтезе и термодинамичке особине вирусних честица, биосинтезе и везивања Omicron JN.1 варијанте SARS-CoV-2
VL  - 89
IS  - 3
SP  - 305
EP  - 320
DO  - 10.2298/JSC240119019P
ER  - 
@article{
author = "Popović, Marko and Stevanović, Maja and Mihailović, Marija",
year = "2024",
abstract = "Breaking news are usually disturbing. Natural disasters, wars, epidemics etc. are reported as breaking news. This paper reports a decreased danger of spreading of epidemics caused by the JN.1 variant, since analyses indicate that (a) infectivity of the new variant is decreased compared to most earlier variants, which is confirmed by the number of cases (7500 daily in USA). Moreover, JN.1 despite the great number of mutations has not been able to achieve the values of Gibbs energy of biosynthesis (and thus virus multiplication rate) of the Hu-1 wild type. The research shows that infectivity and pathogenicity of the JN.1 variant has not reached worrying size, which means that there is no reason to expect a worsening of the epidemiologic situation., Ударне вести су обично узнемирујуће. О природним катастрофама, ратовима, епидемијама итд. се извештава као ударним вестима. У овом раду је приказана смањена опасност од ширења епидемија изазваних варијантом JN.1, јер анализе показују да је (а) инфективност нове варијанте смањена у односу на већину ранијих варијанти, што потврђује и број случајева (7500 дневно у САД). Штавише, JN.1 упркос великом броју мутација није успео да постигне вредности Гибсове енергије биосинтезе (а самим тим и стопе размножавања вируса) дивљег типа Hu.1. Истраживање показује да инфективност и патогеност варијанте JN.1 није достигла забрињавајућу величину, што значи да нема разлога за очекивање погоршање епидемиолошке ситуације.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2, Ударне вести: емпиријске формуле, моларне масе, реакције биосинтезе и термодинамичке особине вирусних честица, биосинтезе и везивања Omicron JN.1 варијанте SARS-CoV-2",
volume = "89",
number = "3",
pages = "305-320",
doi = "10.2298/JSC240119019P"
}
Popović, M., Stevanović, M.,& Mihailović, M.. (2024). Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 89(3), 305-320.
https://doi.org/10.2298/JSC240119019P
Popović M, Stevanović M, Mihailović M. Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2. in Journal of the Serbian Chemical Society. 2024;89(3):305-320.
doi:10.2298/JSC240119019P .
Popović, Marko, Stevanović, Maja, Mihailović, Marija, "Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2" in Journal of the Serbian Chemical Society, 89, no. 3 (2024):305-320,
https://doi.org/10.2298/JSC240119019P . .

Modified Titanium Surface with Nano Amorphous Calcium Phosphate@Chitosan Oligolactate as Ion Loading Platform with Multifunctional Properties for Potential Biomedical Application

Pantović-Pavlović, Marijana; Ignjatović, Nenad; Gudić, Senka; Vrsalović, Ladislav; Božić, Katarina; Popović, Marko; Pavlović, Miroslav

(Springer Science and Business Media LLC, 2024)

TY  - JOUR
AU  - Pantović-Pavlović, Marijana
AU  - Ignjatović, Nenad
AU  - Gudić, Senka
AU  - Vrsalović, Ladislav
AU  - Božić, Katarina
AU  - Popović, Marko
AU  - Pavlović, Miroslav
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7558
AB  - Titanium (Ti) is widely used in medical and dental implants. Calcium phosphate (CPs) coatings enhance Ti implants’ osteoinductive properties, and additives further improve these coatings. Recently, a nano amorphous calcium phosphate (nACP) coating decorated with chitosan oligolactate (ChOL) and selenium (Se) showed immunomodulatory effects. This study investigates the surface morphology, composition, bioactivity, mechanical properties, and Se-release mechanism of the nACP@ChOL-Se hybrid coating on Ti substrates. Amorphous calcium phosphate (ACP) was synthesized, and the nACP@ChOL-Se hybrid coating was deposited on Ti substrates using in situ anaphoretic deposition. Physico-chemical characterization was used to analyze the surface of the coating (scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier Transform Infrared Spectroscopy). The distribution of Se within the coating was examined with energy-dispersive X-ray spectroscopy (EDS). Bioactivity was evaluated in simulated body fluid (SBF), and adhesion was tested using a scratch test method. In vitro testing determined the release mechanism of Se. SEM images illustrated the surface morphology, while AFM provided a detailed analysis of surface roughness. XRD analysis revealed structural and phase composition, and EDS confirmed Se distribution within the coating. The coating exhibited bioactivity in SBF and showed good adhesion according to the scratch test. In vitro testing uncovered the release mechanism of Se from the coating. This study successfully characterized the surface morphology, composition, bioactivity, and Se-release mechanism of the nACP@ChOL-Se hybrid coating on Ti substrates, offering insights for developing immunomodulatory coatings for medical and dental applications.
PB  - Springer Science and Business Media LLC
T2  - Annals of Biomedical Engineering
T1  - Modified Titanium Surface with Nano Amorphous Calcium Phosphate@Chitosan Oligolactate as Ion Loading Platform with Multifunctional Properties for Potential Biomedical Application
DO  - 10.1007/s10439-024-03521-0
ER  - 
@article{
author = "Pantović-Pavlović, Marijana and Ignjatović, Nenad and Gudić, Senka and Vrsalović, Ladislav and Božić, Katarina and Popović, Marko and Pavlović, Miroslav",
year = "2024",
abstract = "Titanium (Ti) is widely used in medical and dental implants. Calcium phosphate (CPs) coatings enhance Ti implants’ osteoinductive properties, and additives further improve these coatings. Recently, a nano amorphous calcium phosphate (nACP) coating decorated with chitosan oligolactate (ChOL) and selenium (Se) showed immunomodulatory effects. This study investigates the surface morphology, composition, bioactivity, mechanical properties, and Se-release mechanism of the nACP@ChOL-Se hybrid coating on Ti substrates. Amorphous calcium phosphate (ACP) was synthesized, and the nACP@ChOL-Se hybrid coating was deposited on Ti substrates using in situ anaphoretic deposition. Physico-chemical characterization was used to analyze the surface of the coating (scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier Transform Infrared Spectroscopy). The distribution of Se within the coating was examined with energy-dispersive X-ray spectroscopy (EDS). Bioactivity was evaluated in simulated body fluid (SBF), and adhesion was tested using a scratch test method. In vitro testing determined the release mechanism of Se. SEM images illustrated the surface morphology, while AFM provided a detailed analysis of surface roughness. XRD analysis revealed structural and phase composition, and EDS confirmed Se distribution within the coating. The coating exhibited bioactivity in SBF and showed good adhesion according to the scratch test. In vitro testing uncovered the release mechanism of Se from the coating. This study successfully characterized the surface morphology, composition, bioactivity, and Se-release mechanism of the nACP@ChOL-Se hybrid coating on Ti substrates, offering insights for developing immunomodulatory coatings for medical and dental applications.",
publisher = "Springer Science and Business Media LLC",
journal = "Annals of Biomedical Engineering",
title = "Modified Titanium Surface with Nano Amorphous Calcium Phosphate@Chitosan Oligolactate as Ion Loading Platform with Multifunctional Properties for Potential Biomedical Application",
doi = "10.1007/s10439-024-03521-0"
}
Pantović-Pavlović, M., Ignjatović, N., Gudić, S., Vrsalović, L., Božić, K., Popović, M.,& Pavlović, M.. (2024). Modified Titanium Surface with Nano Amorphous Calcium Phosphate@Chitosan Oligolactate as Ion Loading Platform with Multifunctional Properties for Potential Biomedical Application. in Annals of Biomedical Engineering
Springer Science and Business Media LLC..
https://doi.org/10.1007/s10439-024-03521-0
Pantović-Pavlović M, Ignjatović N, Gudić S, Vrsalović L, Božić K, Popović M, Pavlović M. Modified Titanium Surface with Nano Amorphous Calcium Phosphate@Chitosan Oligolactate as Ion Loading Platform with Multifunctional Properties for Potential Biomedical Application. in Annals of Biomedical Engineering. 2024;.
doi:10.1007/s10439-024-03521-0 .
Pantović-Pavlović, Marijana, Ignjatović, Nenad, Gudić, Senka, Vrsalović, Ladislav, Božić, Katarina, Popović, Marko, Pavlović, Miroslav, "Modified Titanium Surface with Nano Amorphous Calcium Phosphate@Chitosan Oligolactate as Ion Loading Platform with Multifunctional Properties for Potential Biomedical Application" in Annals of Biomedical Engineering (2024),
https://doi.org/10.1007/s10439-024-03521-0 . .

Critical Review of Selected Analytical Platforms for GC-MS Metabolomics Profiling—Case Study: HS-SPME/GC-MS Analysis of Blackberry’s Aroma

Ljujić, Jovana; Vujisić, Ljubodrag; Tešević, Vele; Sofrenić, Ivana V.; Ivanović, Stefan; Simić, Katarina; Anđelković, Boban

(MDPI, 2024)

TY  - JOUR
AU  - Ljujić, Jovana
AU  - Vujisić, Ljubodrag
AU  - Tešević, Vele
AU  - Sofrenić, Ivana V.
AU  - Ivanović, Stefan
AU  - Simić, Katarina
AU  - Anđelković, Boban
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7574
AB  - Data processing and data extraction are the first, and most often crucial, steps in metabolomics and multivariate data analysis in general. There are several software solutions for these purposes in GC-MS metabolomics. It becomes unclear which platform offers what kind of data and how that information influences the analysis’s conclusions. In this study, selected analytical platforms for GC-MS metabolomics profiling, SpectConnect and XCMS as well as MestReNova software, were used to process the results of the HS-SPME/GC-MS aroma analyses of several blackberry varieties. In addition, a detailed analysis of the identification of the individual components of the blackberry aroma club varieties was performed. In total, 72 components were detected in the XCMS platform, 119 in SpectConnect, and 87 and 167 in MestReNova, with automatic integral and manual correction, respectively, as well as 219 aroma components after manual analysis of GC-MS chromatograms. The obtained datasets were fed, for multivariate data analysis, to SIMCA software, and underwent the creation of PCA, OPLS, and OPLS-DA models. The results of the validation tests and VIP-pred. scores were analyzed in detail.
PB  - MDPI
T2  - Foods
T1  - Critical Review of Selected Analytical Platforms for GC-MS Metabolomics Profiling—Case Study: HS-SPME/GC-MS Analysis of Blackberry’s Aroma
VL  - 13
IS  - 8
SP  - 1222
DO  - 10.3390/foods13081222
ER  - 
@article{
author = "Ljujić, Jovana and Vujisić, Ljubodrag and Tešević, Vele and Sofrenić, Ivana V. and Ivanović, Stefan and Simić, Katarina and Anđelković, Boban",
year = "2024",
abstract = "Data processing and data extraction are the first, and most often crucial, steps in metabolomics and multivariate data analysis in general. There are several software solutions for these purposes in GC-MS metabolomics. It becomes unclear which platform offers what kind of data and how that information influences the analysis’s conclusions. In this study, selected analytical platforms for GC-MS metabolomics profiling, SpectConnect and XCMS as well as MestReNova software, were used to process the results of the HS-SPME/GC-MS aroma analyses of several blackberry varieties. In addition, a detailed analysis of the identification of the individual components of the blackberry aroma club varieties was performed. In total, 72 components were detected in the XCMS platform, 119 in SpectConnect, and 87 and 167 in MestReNova, with automatic integral and manual correction, respectively, as well as 219 aroma components after manual analysis of GC-MS chromatograms. The obtained datasets were fed, for multivariate data analysis, to SIMCA software, and underwent the creation of PCA, OPLS, and OPLS-DA models. The results of the validation tests and VIP-pred. scores were analyzed in detail.",
publisher = "MDPI",
journal = "Foods",
title = "Critical Review of Selected Analytical Platforms for GC-MS Metabolomics Profiling—Case Study: HS-SPME/GC-MS Analysis of Blackberry’s Aroma",
volume = "13",
number = "8",
pages = "1222",
doi = "10.3390/foods13081222"
}
Ljujić, J., Vujisić, L., Tešević, V., Sofrenić, I. V., Ivanović, S., Simić, K.,& Anđelković, B.. (2024). Critical Review of Selected Analytical Platforms for GC-MS Metabolomics Profiling—Case Study: HS-SPME/GC-MS Analysis of Blackberry’s Aroma. in Foods
MDPI., 13(8), 1222.
https://doi.org/10.3390/foods13081222
Ljujić J, Vujisić L, Tešević V, Sofrenić IV, Ivanović S, Simić K, Anđelković B. Critical Review of Selected Analytical Platforms for GC-MS Metabolomics Profiling—Case Study: HS-SPME/GC-MS Analysis of Blackberry’s Aroma. in Foods. 2024;13(8):1222.
doi:10.3390/foods13081222 .
Ljujić, Jovana, Vujisić, Ljubodrag, Tešević, Vele, Sofrenić, Ivana V., Ivanović, Stefan, Simić, Katarina, Anđelković, Boban, "Critical Review of Selected Analytical Platforms for GC-MS Metabolomics Profiling—Case Study: HS-SPME/GC-MS Analysis of Blackberry’s Aroma" in Foods, 13, no. 8 (2024):1222,
https://doi.org/10.3390/foods13081222 . .

Photocatalytically active Ag-doped TiO2 coatings developed by plasma electrolytic oxidation in the presence of colloidal Ag nanoparticles

Radić, Nenad; Ilić, Mila; Stojadinović, Stevan; Milić, Jelena; Avdalović, Jelena; Šaponjić, Zoran

(Elsevier, 2024)

TY  - JOUR
AU  - Radić, Nenad
AU  - Ilić, Mila
AU  - Stojadinović, Stevan
AU  - Milić, Jelena
AU  - Avdalović, Jelena
AU  - Šaponjić, Zoran
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7515
AB  - The plasma electrolytic oxidation process of Ti foil in the presence of a colloidal solution of Ag nanoparticles was used for the synthesis of exceptionally photocatalytically active Ag-doped TiO2 coatings. UV–Vis absorption spectroscopy was applied to follow the changes in the surface plasmon resonance band of the Ag nanoparticles as a function of the Ag:PO43− ratio in a phosphate-based electrolyte solution. Transmission electron microscopy revealed the size of the Ag nanoparticles in the range of 3–12 nm. The XRD patterns of the Ag-doped TiO2 coatings confirmed the crystalline anatase TiO2 phase regardless of the dopant concentration and without metallic Ag or crystalline Ag oxide forms. The typical porous morphology of the Ag–TiO2 coatings was observed by scanning electron microscopy. A significantly improved photocatalytic activity of the Ag–TiO2 coatings in the degradation process of the insecticide lindane (gamma isomer of benzene hexachloride) and test molecule methyl orange compared to pure TiO2 was determined using the GC technique. The degradation efficiency of Ag-doped TiO2 coatings is higher for lindane than for methyl orange.
PB  - Elsevier
T2  - Journal of Physics and Chemistry of Solids
T1  - Photocatalytically active Ag-doped TiO2 coatings developed by plasma electrolytic oxidation in the presence of colloidal Ag nanoparticles
VL  - 188
SP  - 111918
DO  - 10.1016/j.jpcs.2024.111918
ER  - 
@article{
author = "Radić, Nenad and Ilić, Mila and Stojadinović, Stevan and Milić, Jelena and Avdalović, Jelena and Šaponjić, Zoran",
year = "2024",
abstract = "The plasma electrolytic oxidation process of Ti foil in the presence of a colloidal solution of Ag nanoparticles was used for the synthesis of exceptionally photocatalytically active Ag-doped TiO2 coatings. UV–Vis absorption spectroscopy was applied to follow the changes in the surface plasmon resonance band of the Ag nanoparticles as a function of the Ag:PO43− ratio in a phosphate-based electrolyte solution. Transmission electron microscopy revealed the size of the Ag nanoparticles in the range of 3–12 nm. The XRD patterns of the Ag-doped TiO2 coatings confirmed the crystalline anatase TiO2 phase regardless of the dopant concentration and without metallic Ag or crystalline Ag oxide forms. The typical porous morphology of the Ag–TiO2 coatings was observed by scanning electron microscopy. A significantly improved photocatalytic activity of the Ag–TiO2 coatings in the degradation process of the insecticide lindane (gamma isomer of benzene hexachloride) and test molecule methyl orange compared to pure TiO2 was determined using the GC technique. The degradation efficiency of Ag-doped TiO2 coatings is higher for lindane than for methyl orange.",
publisher = "Elsevier",
journal = "Journal of Physics and Chemistry of Solids",
title = "Photocatalytically active Ag-doped TiO2 coatings developed by plasma electrolytic oxidation in the presence of colloidal Ag nanoparticles",
volume = "188",
pages = "111918",
doi = "10.1016/j.jpcs.2024.111918"
}
Radić, N., Ilić, M., Stojadinović, S., Milić, J., Avdalović, J.,& Šaponjić, Z.. (2024). Photocatalytically active Ag-doped TiO2 coatings developed by plasma electrolytic oxidation in the presence of colloidal Ag nanoparticles. in Journal of Physics and Chemistry of Solids
Elsevier., 188, 111918.
https://doi.org/10.1016/j.jpcs.2024.111918
Radić N, Ilić M, Stojadinović S, Milić J, Avdalović J, Šaponjić Z. Photocatalytically active Ag-doped TiO2 coatings developed by plasma electrolytic oxidation in the presence of colloidal Ag nanoparticles. in Journal of Physics and Chemistry of Solids. 2024;188:111918.
doi:10.1016/j.jpcs.2024.111918 .
Radić, Nenad, Ilić, Mila, Stojadinović, Stevan, Milić, Jelena, Avdalović, Jelena, Šaponjić, Zoran, "Photocatalytically active Ag-doped TiO2 coatings developed by plasma electrolytic oxidation in the presence of colloidal Ag nanoparticles" in Journal of Physics and Chemistry of Solids, 188 (2024):111918,
https://doi.org/10.1016/j.jpcs.2024.111918 . .

Prevention of Silica Gel Formation for Eudialyte Study Using New Digestion Reactor

Silin, Ivan; Dertmann, Christian; Cvetković, Vesna S.; Stopić, Srećko; Friedrich, Bernd

(MDPI, 2024)

TY  - JOUR
AU  - Silin, Ivan
AU  - Dertmann, Christian
AU  - Cvetković, Vesna S.
AU  - Stopić, Srećko
AU  - Friedrich, Bernd
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7432
AB  - This work includes a combined hydrometallurgical treatment of a eudialyte ore sample
with a subsequent preparation of leaching residue using mechanical separation methods. Hydrometallurgical treatment contains dry digestion with sulphuric acid at room temperature and filtration of the obtained product. The objectives of adopting these procedures are to test a new digestion reactor in order to prevent silica gel formation from the eudialyte ore. The obtained results revealed that silica gel formation is prevented during dissolution with sulphuric acid. A high leaching efficiency of light rare earth elements (La, Ce, Nd, Y) was reached using the dry digestion process with sulphuric acid, where the starting molarity was 12 mol/L. After the filtration process, magnetic separation is studied as the main method to recover weakly magnetic minerals like amphiboles and pyroxenes from the leaching residue in the magnetic fraction and feldspars in the nonmagnetic fraction. A new combined research strategy was developed for the production of different concentrates such as the one bearing Zr, Hf, and Nb.
PB  - MDPI
T2  - Minerals
T1  - Prevention of Silica Gel Formation for Eudialyte Study Using New Digestion Reactor
VL  - 14
IS  - 2
SP  - 124
DO  - 10.3390/min14020124
ER  - 
@article{
author = "Silin, Ivan and Dertmann, Christian and Cvetković, Vesna S. and Stopić, Srećko and Friedrich, Bernd",
year = "2024",
abstract = "This work includes a combined hydrometallurgical treatment of a eudialyte ore sample
with a subsequent preparation of leaching residue using mechanical separation methods. Hydrometallurgical treatment contains dry digestion with sulphuric acid at room temperature and filtration of the obtained product. The objectives of adopting these procedures are to test a new digestion reactor in order to prevent silica gel formation from the eudialyte ore. The obtained results revealed that silica gel formation is prevented during dissolution with sulphuric acid. A high leaching efficiency of light rare earth elements (La, Ce, Nd, Y) was reached using the dry digestion process with sulphuric acid, where the starting molarity was 12 mol/L. After the filtration process, magnetic separation is studied as the main method to recover weakly magnetic minerals like amphiboles and pyroxenes from the leaching residue in the magnetic fraction and feldspars in the nonmagnetic fraction. A new combined research strategy was developed for the production of different concentrates such as the one bearing Zr, Hf, and Nb.",
publisher = "MDPI",
journal = "Minerals",
title = "Prevention of Silica Gel Formation for Eudialyte Study Using New Digestion Reactor",
volume = "14",
number = "2",
pages = "124",
doi = "10.3390/min14020124"
}
Silin, I., Dertmann, C., Cvetković, V. S., Stopić, S.,& Friedrich, B.. (2024). Prevention of Silica Gel Formation for Eudialyte Study Using New Digestion Reactor. in Minerals
MDPI., 14(2), 124.
https://doi.org/10.3390/min14020124
Silin I, Dertmann C, Cvetković VS, Stopić S, Friedrich B. Prevention of Silica Gel Formation for Eudialyte Study Using New Digestion Reactor. in Minerals. 2024;14(2):124.
doi:10.3390/min14020124 .
Silin, Ivan, Dertmann, Christian, Cvetković, Vesna S., Stopić, Srećko, Friedrich, Bernd, "Prevention of Silica Gel Formation for Eudialyte Study Using New Digestion Reactor" in Minerals, 14, no. 2 (2024):124,
https://doi.org/10.3390/min14020124 . .

Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2

Popović, Marko; Stevanović, Maja; Mihailović, Marija

(Serbian Chemical Society, 2024)

TY  - JOUR
AU  - Popović, Marko
AU  - Stevanović, Maja
AU  - Mihailović, Marija
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7518
AB  - Breaking news are usually disturbing. Natural disasters, wars, epidemics etc. are reported as breaking news. This paper reports a decreased danger of spreading of epidemics caused by the JN.1 variant, since analyses indicate that (a) infectivity of the new variant is decreased compared to most earlier variants, which is confirmed by the number of cases (7500 daily in USA). Moreover, JN.1 despite the great number of mutations has not been able to achieve the values of Gibbs energy of biosynthesis (and thus virus multiplication rate) of the Hu-1 wild type. The research shows that infectivity and pathogenicity of the JN.1 variant has not reached worrying size, which means that there is no reason to expect a worsening of the epidemiologic situation.
AB  - Ударне вести су обично узнемирујуће. О природним катастрофама, ратовима, епидемијама итд. се извештава као ударним вестима. У овом раду је приказана смањена опасност од ширења епидемија изазваних варијантом JN.1, јер анализе показују да је (а) инфективност нове варијанте смањена у односу на већину ранијих варијанти, што потврђује и број случајева (7500 дневно у САД). Штавише, JN.1 упркос великом броју мутација није успео да постигне вредности Гибсове енергије биосинтезе (а самим тим и стопе размножавања вируса) дивљег типа Hu.1. Истраживање показује да инфективност и патогеност варијанте JN.1 није достигла забрињавајућу величину, што значи да нема разлога за очекивање погоршање епидемиолошке ситуације.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2
T1  - Ударне вести: емпиријске формуле, моларне масе, реакције биосинтезе и термодинамичке особине вирусних честица, биосинтезе и везивања Omicron JN.1 варијанте SARS-CoV-2
VL  - 89
IS  - 3
SP  - 305
EP  - 320
DO  - 10.2298/JSC240119019P
ER  - 
@article{
author = "Popović, Marko and Stevanović, Maja and Mihailović, Marija",
year = "2024",
abstract = "Breaking news are usually disturbing. Natural disasters, wars, epidemics etc. are reported as breaking news. This paper reports a decreased danger of spreading of epidemics caused by the JN.1 variant, since analyses indicate that (a) infectivity of the new variant is decreased compared to most earlier variants, which is confirmed by the number of cases (7500 daily in USA). Moreover, JN.1 despite the great number of mutations has not been able to achieve the values of Gibbs energy of biosynthesis (and thus virus multiplication rate) of the Hu-1 wild type. The research shows that infectivity and pathogenicity of the JN.1 variant has not reached worrying size, which means that there is no reason to expect a worsening of the epidemiologic situation., Ударне вести су обично узнемирујуће. О природним катастрофама, ратовима, епидемијама итд. се извештава као ударним вестима. У овом раду је приказана смањена опасност од ширења епидемија изазваних варијантом JN.1, јер анализе показују да је (а) инфективност нове варијанте смањена у односу на већину ранијих варијанти, што потврђује и број случајева (7500 дневно у САД). Штавише, JN.1 упркос великом броју мутација није успео да постигне вредности Гибсове енергије биосинтезе (а самим тим и стопе размножавања вируса) дивљег типа Hu.1. Истраживање показује да инфективност и патогеност варијанте JN.1 није достигла забрињавајућу величину, што значи да нема разлога за очекивање погоршање епидемиолошке ситуације.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2, Ударне вести: емпиријске формуле, моларне масе, реакције биосинтезе и термодинамичке особине вирусних честица, биосинтезе и везивања Omicron JN.1 варијанте SARS-CoV-2",
volume = "89",
number = "3",
pages = "305-320",
doi = "10.2298/JSC240119019P"
}
Popović, M., Stevanović, M.,& Mihailović, M.. (2024). Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 89(3), 305-320.
https://doi.org/10.2298/JSC240119019P
Popović M, Stevanović M, Mihailović M. Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2. in Journal of the Serbian Chemical Society. 2024;89(3):305-320.
doi:10.2298/JSC240119019P .
Popović, Marko, Stevanović, Maja, Mihailović, Marija, "Breaking news: Empirical formulas, molar masses, biosynthesis reactions, and thermodynamic properties of virus particles, biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2" in Journal of the Serbian Chemical Society, 89, no. 3 (2024):305-320,
https://doi.org/10.2298/JSC240119019P . .

Microbial bioremediation of the oil polluted environment and the sustainable development goals of pillar Planet of the Agenda 2030

Milić, Jelena; Avdalović, Jelena; Šolević-Knudsen, Tatjana

(Srpinger Nature, 2024)

TY  - JOUR
AU  - Milić, Jelena
AU  - Avdalović, Jelena
AU  - Šolević-Knudsen, Tatjana
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7553
AB  - Sustainable development is a concept that is based on the development of the human society without compromising the natural resources, which should improve human lives and protect the environment for future generations. The UN Agenda 2030 has set 17 goals aimed to transform the development of humanity in accordance with the environment, and with the social and economic rights. This concept is recognized as one of the most important concepts for the future international development. One of the four main pillars of the Agenda 2030 is a pillar Planet, which consists of five sustainability development goals (SDGs) aiming to clean the pollution on the Earth and set the sustainable use of the Earth’s resources. The aim of paper is to demonstrate the role of oil pollution bioremediation in achieving SDGs by assessing the importance of this technology and using microorganisms as natural capacity of the Earth for self-cleaning. This review article highlights the applicability of bioremediation as an oil pollution cleaning technique and reviews the compliance of bioremediation with the SDGs. According to this review, bioremediation techniques are an important element which can help in integrated approach to achieve several goals set by the Agenda 2030. Due to the incomplete biodegradation and co-contamination by other chemicals, further research is needed in order to make bioremediation a more effective biotechnological strategy. It is necessary to integrate the Agenda 2030 to university curricula and stream SDGs into scientific funding by opening dedicated calls that contribute to selected SDGs of the Agenda 2030.
PB  - Srpinger Nature
T2  - Environment, Development and Sustainability
T1  - Microbial bioremediation of the oil polluted environment and the sustainable development goals of pillar Planet of the Agenda 2030
DO  - 10.1007/s10668-024-04848-3
ER  - 
@article{
author = "Milić, Jelena and Avdalović, Jelena and Šolević-Knudsen, Tatjana",
year = "2024",
abstract = "Sustainable development is a concept that is based on the development of the human society without compromising the natural resources, which should improve human lives and protect the environment for future generations. The UN Agenda 2030 has set 17 goals aimed to transform the development of humanity in accordance with the environment, and with the social and economic rights. This concept is recognized as one of the most important concepts for the future international development. One of the four main pillars of the Agenda 2030 is a pillar Planet, which consists of five sustainability development goals (SDGs) aiming to clean the pollution on the Earth and set the sustainable use of the Earth’s resources. The aim of paper is to demonstrate the role of oil pollution bioremediation in achieving SDGs by assessing the importance of this technology and using microorganisms as natural capacity of the Earth for self-cleaning. This review article highlights the applicability of bioremediation as an oil pollution cleaning technique and reviews the compliance of bioremediation with the SDGs. According to this review, bioremediation techniques are an important element which can help in integrated approach to achieve several goals set by the Agenda 2030. Due to the incomplete biodegradation and co-contamination by other chemicals, further research is needed in order to make bioremediation a more effective biotechnological strategy. It is necessary to integrate the Agenda 2030 to university curricula and stream SDGs into scientific funding by opening dedicated calls that contribute to selected SDGs of the Agenda 2030.",
publisher = "Srpinger Nature",
journal = "Environment, Development and Sustainability",
title = "Microbial bioremediation of the oil polluted environment and the sustainable development goals of pillar Planet of the Agenda 2030",
doi = "10.1007/s10668-024-04848-3"
}
Milić, J., Avdalović, J.,& Šolević-Knudsen, T.. (2024). Microbial bioremediation of the oil polluted environment and the sustainable development goals of pillar Planet of the Agenda 2030. in Environment, Development and Sustainability
Srpinger Nature..
https://doi.org/10.1007/s10668-024-04848-3
Milić J, Avdalović J, Šolević-Knudsen T. Microbial bioremediation of the oil polluted environment and the sustainable development goals of pillar Planet of the Agenda 2030. in Environment, Development and Sustainability. 2024;.
doi:10.1007/s10668-024-04848-3 .
Milić, Jelena, Avdalović, Jelena, Šolević-Knudsen, Tatjana, "Microbial bioremediation of the oil polluted environment and the sustainable development goals of pillar Planet of the Agenda 2030" in Environment, Development and Sustainability (2024),
https://doi.org/10.1007/s10668-024-04848-3 . .

Microplastics in the Danube River and Its Main Tributaries - Ingestion by Freshwater Macroinvertebrates

Stanković, Jelena; Milošević, Đurađ; Paunović, Momir; Jovanović, Boris; Popović, Nataša; Tomović, Jelena; Atanacković, Ana; Radulović, Katarina; Lončarević, Davor; Raković, Maja

(MDPI, 2024)

TY  - JOUR
AU  - Stanković, Jelena
AU  - Milošević, Đurađ
AU  - Paunović, Momir
AU  - Jovanović, Boris
AU  - Popović, Nataša
AU  - Tomović, Jelena
AU  - Atanacković, Ana
AU  - Radulović, Katarina
AU  - Lončarević, Davor
AU  - Raković, Maja
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7554
AB  - This study was carried out at the Danube River and its tributaries during the Joint Danube
Survey 4 (JDS4) expedition. Three freshwater benthic species were used to estimate the quantity
of microplastics (MPs): Corbicula spp., Limnodrilus hoffmeisteri (Claparede, 1862), and Polypedilum nubeculosum (Meigen, 1804). Following the kick and sweep technique, individuals were sampled using a hand net or dredge. In order to estimate the number of MP articles/individual particles/g wet body mass, the body mass and total length of all specimens were measured. Alkaline (Corbicula spp.and L. hoffmaisteri) and enzymatic (P. nubeculosum) protocols were performed for tissue degradation. All samples were filtered through glass microfiber filters (mesh size 0.5 μm). The particles were photographed, measured, and counted. A total of 1904, 169, and 204 MPs were isolated from Corbicula spp., L. hoffmaisteri, and P. nubeculosum, respectively. To confirm the chemical composition of isolated MPs, a subsample of 46 particles of the fragmented particles from 14 sampling sites was analysed via μ-ATR-FTIR spectroscopy analysis. The particles were characterised as polycarbonate (PC), polyethylene terephthalate (PET), polypropylene–polyethylene copolymer (PP-PE), nylon (polyamide-PA) and cellophane, with the domination of PET.
PB  - MDPI
T2  - Water
T1  - Microplastics in the Danube River and Its Main Tributaries - Ingestion by Freshwater Macroinvertebrates
VL  - 16
IS  - 7
SP  - 962
DO  - 10.3390/w16070962
ER  - 
@article{
author = "Stanković, Jelena and Milošević, Đurađ and Paunović, Momir and Jovanović, Boris and Popović, Nataša and Tomović, Jelena and Atanacković, Ana and Radulović, Katarina and Lončarević, Davor and Raković, Maja",
year = "2024",
abstract = "This study was carried out at the Danube River and its tributaries during the Joint Danube
Survey 4 (JDS4) expedition. Three freshwater benthic species were used to estimate the quantity
of microplastics (MPs): Corbicula spp., Limnodrilus hoffmeisteri (Claparede, 1862), and Polypedilum nubeculosum (Meigen, 1804). Following the kick and sweep technique, individuals were sampled using a hand net or dredge. In order to estimate the number of MP articles/individual particles/g wet body mass, the body mass and total length of all specimens were measured. Alkaline (Corbicula spp.and L. hoffmaisteri) and enzymatic (P. nubeculosum) protocols were performed for tissue degradation. All samples were filtered through glass microfiber filters (mesh size 0.5 μm). The particles were photographed, measured, and counted. A total of 1904, 169, and 204 MPs were isolated from Corbicula spp., L. hoffmaisteri, and P. nubeculosum, respectively. To confirm the chemical composition of isolated MPs, a subsample of 46 particles of the fragmented particles from 14 sampling sites was analysed via μ-ATR-FTIR spectroscopy analysis. The particles were characterised as polycarbonate (PC), polyethylene terephthalate (PET), polypropylene–polyethylene copolymer (PP-PE), nylon (polyamide-PA) and cellophane, with the domination of PET.",
publisher = "MDPI",
journal = "Water",
title = "Microplastics in the Danube River and Its Main Tributaries - Ingestion by Freshwater Macroinvertebrates",
volume = "16",
number = "7",
pages = "962",
doi = "10.3390/w16070962"
}
Stanković, J., Milošević, Đ., Paunović, M., Jovanović, B., Popović, N., Tomović, J., Atanacković, A., Radulović, K., Lončarević, D.,& Raković, M.. (2024). Microplastics in the Danube River and Its Main Tributaries - Ingestion by Freshwater Macroinvertebrates. in Water
MDPI., 16(7), 962.
https://doi.org/10.3390/w16070962
Stanković J, Milošević Đ, Paunović M, Jovanović B, Popović N, Tomović J, Atanacković A, Radulović K, Lončarević D, Raković M. Microplastics in the Danube River and Its Main Tributaries - Ingestion by Freshwater Macroinvertebrates. in Water. 2024;16(7):962.
doi:10.3390/w16070962 .
Stanković, Jelena, Milošević, Đurađ, Paunović, Momir, Jovanović, Boris, Popović, Nataša, Tomović, Jelena, Atanacković, Ana, Radulović, Katarina, Lončarević, Davor, Raković, Maja, "Microplastics in the Danube River and Its Main Tributaries - Ingestion by Freshwater Macroinvertebrates" in Water, 16, no. 7 (2024):962,
https://doi.org/10.3390/w16070962 . .
3
1
1

Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles

Anđelković, Ljubica; Šuljagić, Marija; Pavlović, Vladimir; Mirković, Miljana; Vrbica, Boško; Novaković, Irena; Stanković, Dalibor; Kremenović, Aleksandar; Uskoković, Vuk

(Elsevier, 2024)

TY  - JOUR
AU  - Anđelković, Ljubica
AU  - Šuljagić, Marija
AU  - Pavlović, Vladimir
AU  - Mirković, Miljana
AU  - Vrbica, Boško
AU  - Novaković, Irena
AU  - Stanković, Dalibor
AU  - Kremenović, Aleksandar
AU  - Uskoković, Vuk
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7552
AB  - Metals and metal oxides have subpar antibacterial activities compared to those of small-molecule antibiotics, yet there are hopes that with proper compositional and structural adjustments this gap might be bridged. In this study, titanium dioxide (TiO2) nanoparticles were mechanically activated and combined with particulate silver through simple reduction process elicited by UV irradiation and assisted with the ultrasound. The resulting powders in various combinations (Ag vs. no Ag, activated vs. non-activated) were characterized using a range of experimental techniques and assessed for their antibacterial activities. The preparation procedure presented in this work prevails over the disadvantages of many chemical routes, most critically by avoiding the use of toxic substances. The mechanical activation did not reduce the particle size or crystallinity of TiO2 nor did it consistently alter the bandgap, yet it enabled the doubling of the amount of silver incorporable into the material. Further, while both mechanical activation and the addition of silver in the amount not exceeding 0.5 wt% produced barely detectable structural changes in the material, they both augmented its antibacterial activity. The precursor TiO2 powder produced no inhibition zone against any of the four bacterial species tested, while the mechanical activation of TiO2 led to the formation of distinct inhibition zones against each of the four bacterial species tested. The addition of silver to activated TiO2 further widened the inhibition zones and it also imparted the antibacterial activity to non-activated TiO2. The boost in the antibacterial activity achieved by the short mechanical activation was of a similar magnitude as the boost obtained after the addition of silver. The antibacterial activity was not different for different species when no silver was added to the system. However, with the addition of silver, species selectivity was obtained, as the composites were more effective against the two Gram-negative species (Escherichia coli and Klebsiella pneumoniae) than against the two Gram-positive ones (Staphylococcus aureus and Bacillus subtilis). The antibacterial activity increased with the addition of silver in the broth assay, but it was mediocre compared to that detected in the agar assay, attesting to the poor dispersability of the powders and their best performance when the bacterial cells migrate to the composite surface than vice versa. The findings of this study give hope that with appropriate microstructural or compositional alterations, the antibacterial activity of metal oxide powders and inorganic materials in general can be made comparable to that of small-molecule antibiotics.
PB  - Elsevier
T2  - Colloids and Surfaces A: Physicochemical and Engineering Aspects
T1  - Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles
VL  - 691
SP  - 133890
DO  - 10.1016/j.colsurfa.2024.133890
ER  - 
@article{
author = "Anđelković, Ljubica and Šuljagić, Marija and Pavlović, Vladimir and Mirković, Miljana and Vrbica, Boško and Novaković, Irena and Stanković, Dalibor and Kremenović, Aleksandar and Uskoković, Vuk",
year = "2024",
abstract = "Metals and metal oxides have subpar antibacterial activities compared to those of small-molecule antibiotics, yet there are hopes that with proper compositional and structural adjustments this gap might be bridged. In this study, titanium dioxide (TiO2) nanoparticles were mechanically activated and combined with particulate silver through simple reduction process elicited by UV irradiation and assisted with the ultrasound. The resulting powders in various combinations (Ag vs. no Ag, activated vs. non-activated) were characterized using a range of experimental techniques and assessed for their antibacterial activities. The preparation procedure presented in this work prevails over the disadvantages of many chemical routes, most critically by avoiding the use of toxic substances. The mechanical activation did not reduce the particle size or crystallinity of TiO2 nor did it consistently alter the bandgap, yet it enabled the doubling of the amount of silver incorporable into the material. Further, while both mechanical activation and the addition of silver in the amount not exceeding 0.5 wt% produced barely detectable structural changes in the material, they both augmented its antibacterial activity. The precursor TiO2 powder produced no inhibition zone against any of the four bacterial species tested, while the mechanical activation of TiO2 led to the formation of distinct inhibition zones against each of the four bacterial species tested. The addition of silver to activated TiO2 further widened the inhibition zones and it also imparted the antibacterial activity to non-activated TiO2. The boost in the antibacterial activity achieved by the short mechanical activation was of a similar magnitude as the boost obtained after the addition of silver. The antibacterial activity was not different for different species when no silver was added to the system. However, with the addition of silver, species selectivity was obtained, as the composites were more effective against the two Gram-negative species (Escherichia coli and Klebsiella pneumoniae) than against the two Gram-positive ones (Staphylococcus aureus and Bacillus subtilis). The antibacterial activity increased with the addition of silver in the broth assay, but it was mediocre compared to that detected in the agar assay, attesting to the poor dispersability of the powders and their best performance when the bacterial cells migrate to the composite surface than vice versa. The findings of this study give hope that with appropriate microstructural or compositional alterations, the antibacterial activity of metal oxide powders and inorganic materials in general can be made comparable to that of small-molecule antibiotics.",
publisher = "Elsevier",
journal = "Colloids and Surfaces A: Physicochemical and Engineering Aspects",
title = "Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles",
volume = "691",
pages = "133890",
doi = "10.1016/j.colsurfa.2024.133890"
}
Anđelković, L., Šuljagić, M., Pavlović, V., Mirković, M., Vrbica, B., Novaković, I., Stanković, D., Kremenović, A.,& Uskoković, V.. (2024). Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles. in Colloids and Surfaces A: Physicochemical and Engineering Aspects
Elsevier., 691, 133890.
https://doi.org/10.1016/j.colsurfa.2024.133890
Anđelković L, Šuljagić M, Pavlović V, Mirković M, Vrbica B, Novaković I, Stanković D, Kremenović A, Uskoković V. Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles. in Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2024;691:133890.
doi:10.1016/j.colsurfa.2024.133890 .
Anđelković, Ljubica, Šuljagić, Marija, Pavlović, Vladimir, Mirković, Miljana, Vrbica, Boško, Novaković, Irena, Stanković, Dalibor, Kremenović, Aleksandar, Uskoković, Vuk, "Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles" in Colloids and Surfaces A: Physicochemical and Engineering Aspects, 691 (2024):133890,
https://doi.org/10.1016/j.colsurfa.2024.133890 . .