TY  - JOUR
AU  - Karaman, M.
AU  - Tesanovic, K.
AU  - Novakovic, A.
AU  - Jakovljević, Dragica
AU  - Janjusevic, L.
AU  - Sibul, F.
AU  - Pejin, Boris
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2388
AB  - In vitro acetylholinesterase (AChE) inhibitory activity of an autochthonous sample of the mushroom Coprinus comatus (encompassing fruiting body FB, mycelia M and filtrate F from the submerged cultivation) was the subject of this study. C. comatus F extract exhibited rather potent anti-AChE activity (73.0 ± 1.5%) at in liquid conditions, comparable to those of the conventional drug donepezil (80.6 ± 1.4%). Also, the same extract exhibited high anti-AChE activity (1 µg) in solid. While its FTIR spectrum indicated the presence of phenolic compounds, quercetin (28.1 µg g−1 d.w.) was found to affect the observed bioactivity (59.8 ± 0.9%). This is the first report of profound anti-AChE activity of any C. comatus extract, a medicinal mushroom that has been successfully cultivated in P.R. China, due to the demanding needs of food industry.
PB  - Taylor and Francis Ltd.
T2  - Natural Product Research
T1  - Coprinus comatus filtrate extract, a novel neuroprotective agent of natural origin
VL  - 34
IS  - 16
SP  - 2346
EP  - 2350
DO  - 10.1080/14786419.2018.1533831
ER  - 

@article{
author = "Karaman, M. and Tesanovic, K. and Novakovic, A. and Jakovljević, Dragica and Janjusevic, L. and Sibul, F. and Pejin, Boris",
year = "2018",
abstract = "In vitro acetylholinesterase (AChE) inhibitory activity of an autochthonous sample of the mushroom Coprinus comatus (encompassing fruiting body FB, mycelia M and filtrate F from the submerged cultivation) was the subject of this study. C. comatus F extract exhibited rather potent anti-AChE activity (73.0 ± 1.5%) at in liquid conditions, comparable to those of the conventional drug donepezil (80.6 ± 1.4%). Also, the same extract exhibited high anti-AChE activity (1 µg) in solid. While its FTIR spectrum indicated the presence of phenolic compounds, quercetin (28.1 µg g−1 d.w.) was found to affect the observed bioactivity (59.8 ± 0.9%). This is the first report of profound anti-AChE activity of any C. comatus extract, a medicinal mushroom that has been successfully cultivated in P.R. China, due to the demanding needs of food industry.",
publisher = "Taylor and Francis Ltd.",
journal = "Natural Product Research",
title = "Coprinus comatus filtrate extract, a novel neuroprotective agent of natural origin",
volume = "34",
number = "16",
pages = "2346-2350",
doi = "10.1080/14786419.2018.1533831"
}

Karaman, M., Tesanovic, K., Novakovic, A., Jakovljević, D., Janjusevic, L., Sibul, F.,& Pejin, B.. (2018). Coprinus comatus filtrate extract, a novel neuroprotective agent of natural origin. in Natural Product Research
Taylor and Francis Ltd.., 34(16), 2346-2350.
https://doi.org/10.1080/14786419.2018.1533831

Karaman M, Tesanovic K, Novakovic A, Jakovljević D, Janjusevic L, Sibul F, Pejin B. Coprinus comatus filtrate extract, a novel neuroprotective agent of natural origin. in Natural Product Research. 2018;34(16):2346-2350.
doi:10.1080/14786419.2018.1533831 .

Karaman, M., Tesanovic, K., Novakovic, A., Jakovljević, Dragica, Janjusevic, L., Sibul, F., Pejin, Boris, "Coprinus comatus filtrate extract, a novel neuroprotective agent of natural origin" in Natural Product Research, 34, no. 16 (2018):2346-2350,
https://doi.org/10.1080/14786419.2018.1533831 . .

TY  - JOUR
AU  - Radosavljevic, Jasna Simonovic
AU  - Pristov, Jelena Bogdanovic
AU  - Mitrović, Aleksandra Lj.
AU  - Steinbach, Gabor
AU  - Mouille, Gregory
AU  - Tufegdžić, Srđan
AU  - Maksimović, Vuk
AU  - Mutavdzic, Dragosav
AU  - Janosevic, Dusica
AU  - Vuković, Marina
AU  - Garab, Gyozo
AU  - Radotić, Ksenija
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2480
AB  - In the original publication of the article, one of the project numbers was omitted in the Acknowledgments. The correct version is provided below.
PB  - Springer, Dordrecht
T2  - Cellulose
T1  - Correction to: Parenchyma cell wall structure in twining stem of Dioscorea balcanica (vol 24, pg 4653, 2017)
VL  - 25
IS  - 4
SP  - 2767
EP  - 2767
DO  - 10.1007/s10570-018-1706-6
ER  - 

@article{
author = "Radosavljevic, Jasna Simonovic and Pristov, Jelena Bogdanovic and Mitrović, Aleksandra Lj. and Steinbach, Gabor and Mouille, Gregory and Tufegdžić, Srđan and Maksimović, Vuk and Mutavdzic, Dragosav and Janosevic, Dusica and Vuković, Marina and Garab, Gyozo and Radotić, Ksenija",
year = "2018",
abstract = "In the original publication of the article, one of the project numbers was omitted in the Acknowledgments. The correct version is provided below.",
publisher = "Springer, Dordrecht",
journal = "Cellulose",
title = "Correction to: Parenchyma cell wall structure in twining stem of Dioscorea balcanica (vol 24, pg 4653, 2017)",
volume = "25",
number = "4",
pages = "2767-2767",
doi = "10.1007/s10570-018-1706-6"
}

Radosavljevic, J. S., Pristov, J. B., Mitrović, A. Lj., Steinbach, G., Mouille, G., Tufegdžić, S., Maksimović, V., Mutavdzic, D., Janosevic, D., Vuković, M., Garab, G.,& Radotić, K.. (2018). Correction to: Parenchyma cell wall structure in twining stem of Dioscorea balcanica (vol 24, pg 4653, 2017). in Cellulose
Springer, Dordrecht., 25(4), 2767-2767.
https://doi.org/10.1007/s10570-018-1706-6

Radosavljevic JS, Pristov JB, Mitrović AL, Steinbach G, Mouille G, Tufegdžić S, Maksimović V, Mutavdzic D, Janosevic D, Vuković M, Garab G, Radotić K. Correction to: Parenchyma cell wall structure in twining stem of Dioscorea balcanica (vol 24, pg 4653, 2017). in Cellulose. 2018;25(4):2767-2767.
doi:10.1007/s10570-018-1706-6 .

Radosavljevic, Jasna Simonovic, Pristov, Jelena Bogdanovic, Mitrović, Aleksandra Lj., Steinbach, Gabor, Mouille, Gregory, Tufegdžić, Srđan, Maksimović, Vuk, Mutavdzic, Dragosav, Janosevic, Dusica, Vuković, Marina, Garab, Gyozo, Radotić, Ksenija, "Correction to: Parenchyma cell wall structure in twining stem of Dioscorea balcanica (vol 24, pg 4653, 2017)" in Cellulose, 25, no. 4 (2018):2767-2767,
https://doi.org/10.1007/s10570-018-1706-6 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Vujisić, Ljubodrag V.
AU  - Sabovljević, Marko
AU  - Tešević, Vele
AU  - Vajs, Vlatka
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2725
AB  - The fatty acid compositions of the moss species Atrichum undulatum (Hedw.) P. Beauv. (Polytrichaceae) and Hypnum andoi A.J.E. Sm. (Hypnaceae) collected in winter time were analysed by gas chromatography (GC) and gas chromatography mass spectrometry (GC-MS) as a contribution to their chemistry. Eight fatty acids were identified in the chloroform/methanol extract 1:1 of A. undulatum (linoleic acid, 26.80%, palmitic acid, 22.17%, alpha-linolenic acid, 20.50%, oleic acid, 18.49%, arachidonic acid, 6.21%, stearic acid, 3.34%, cis-5,8,11,14,17-eicosapentaenoic acid, 1.52% and behenic acid, 1.01%), while six fatty acids were found in the same type of extract of H. andoi (palmitic acid, 63.48%, erucic acid, 12.38%, stearic acid, 8.08%, behenic acid, 6.26%, lignoceric acid, 5.16% and arachidic acid, 4.64%). According to this study, the moss A. undulatum can be considered as a good source of both essential fatty acids for humans (linoleic acid and alpha-linolenic acid) during the winter.
AB  - Kao doprinos izučavanju njihovog hemijskog sastava, u ovom radu GC i GC-MS analizom ispitivane su masne kiseline mahovina Atrichum undulatum (Hedw.) P. Beauv. (Polytrichaceae) i Hypnum andoi A.J.E. Sm. (Hypnaceae) sakupljene za vreme zimskog doba. U ekstraktu hloroform/metanol 1:1 vrste A. undulatum identifikovano je osam viših masnih kiselina (linolna kiselina, 26,80%, palmitinska kiselina, 22,17%, α-linolenska kiselina, 20,50%, oleinska kiselina, 18,49%, arahidonska kiselina, 6,21%, stearinska kiselina, 3,34%, cis-5,8,11,14,17-eikosapentaenska kiselina, 1,52% i behenska kiselina, 1,01%), dok je u istom ekstraktu vrste H. andoi nađeno šest viših masnih kiselina (palmitinska kiselina, 63,48%, erukinska kiselina, 12,38%, stearinska kiselina, 8,08%, behenska kiselina, 6,26%, lignocerinska kiselina, 5,16% i arahidinska kiselina, 4,64%). Dobijeni rezultati ukazuju da u ispitivanom vremenskom periodu mahovina A. undulatum predstavlja dobar izvor linolne i α-linolenske kiseline, esencijalnih masnih kiselina za ljude.
PB  - Assoc Chemists & Chemical Engineers Of Serbia, Belgrade
T2  - Hemijska industrija
T1  - Fatty acid chemistry of Atrichum undulatum and Hypnum andoi
T1  - Hemija masnih kiselina Atrichum undulatum i Hypnum andoi
VL  - 66
IS  - 2
SP  - 207
EP  - 209
DO  - 10.2298/HEMIND110918074P
ER  - 

@article{
author = "Pejin, Boris and Vujisić, Ljubodrag V. and Sabovljević, Marko and Tešević, Vele and Vajs, Vlatka",
year = "2012",
abstract = "The fatty acid compositions of the moss species Atrichum undulatum (Hedw.) P. Beauv. (Polytrichaceae) and Hypnum andoi A.J.E. Sm. (Hypnaceae) collected in winter time were analysed by gas chromatography (GC) and gas chromatography mass spectrometry (GC-MS) as a contribution to their chemistry. Eight fatty acids were identified in the chloroform/methanol extract 1:1 of A. undulatum (linoleic acid, 26.80%, palmitic acid, 22.17%, alpha-linolenic acid, 20.50%, oleic acid, 18.49%, arachidonic acid, 6.21%, stearic acid, 3.34%, cis-5,8,11,14,17-eicosapentaenoic acid, 1.52% and behenic acid, 1.01%), while six fatty acids were found in the same type of extract of H. andoi (palmitic acid, 63.48%, erucic acid, 12.38%, stearic acid, 8.08%, behenic acid, 6.26%, lignoceric acid, 5.16% and arachidic acid, 4.64%). According to this study, the moss A. undulatum can be considered as a good source of both essential fatty acids for humans (linoleic acid and alpha-linolenic acid) during the winter., Kao doprinos izučavanju njihovog hemijskog sastava, u ovom radu GC i GC-MS analizom ispitivane su masne kiseline mahovina Atrichum undulatum (Hedw.) P. Beauv. (Polytrichaceae) i Hypnum andoi A.J.E. Sm. (Hypnaceae) sakupljene za vreme zimskog doba. U ekstraktu hloroform/metanol 1:1 vrste A. undulatum identifikovano je osam viših masnih kiselina (linolna kiselina, 26,80%, palmitinska kiselina, 22,17%, α-linolenska kiselina, 20,50%, oleinska kiselina, 18,49%, arahidonska kiselina, 6,21%, stearinska kiselina, 3,34%, cis-5,8,11,14,17-eikosapentaenska kiselina, 1,52% i behenska kiselina, 1,01%), dok je u istom ekstraktu vrste H. andoi nađeno šest viših masnih kiselina (palmitinska kiselina, 63,48%, erukinska kiselina, 12,38%, stearinska kiselina, 8,08%, behenska kiselina, 6,26%, lignocerinska kiselina, 5,16% i arahidinska kiselina, 4,64%). Dobijeni rezultati ukazuju da u ispitivanom vremenskom periodu mahovina A. undulatum predstavlja dobar izvor linolne i α-linolenske kiseline, esencijalnih masnih kiselina za ljude.",
publisher = "Assoc Chemists & Chemical Engineers Of Serbia, Belgrade",
journal = "Hemijska industrija",
title = "Fatty acid chemistry of Atrichum undulatum and Hypnum andoi, Hemija masnih kiselina Atrichum undulatum i Hypnum andoi",
volume = "66",
number = "2",
pages = "207-209",
doi = "10.2298/HEMIND110918074P"
}

Pejin, B., Vujisić, L. V., Sabovljević, M., Tešević, V.,& Vajs, V.. (2012). Fatty acid chemistry of Atrichum undulatum and Hypnum andoi. in Hemijska industrija
Assoc Chemists & Chemical Engineers Of Serbia, Belgrade., 66(2), 207-209.
https://doi.org/10.2298/HEMIND110918074P

Pejin B, Vujisić LV, Sabovljević M, Tešević V, Vajs V. Fatty acid chemistry of Atrichum undulatum and Hypnum andoi. in Hemijska industrija. 2012;66(2):207-209.
doi:10.2298/HEMIND110918074P .

Pejin, Boris, Vujisić, Ljubodrag V., Sabovljević, Marko, Tešević, Vele, Vajs, Vlatka, "Fatty acid chemistry of Atrichum undulatum and Hypnum andoi" in Hemijska industrija, 66, no. 2 (2012):207-209,
https://doi.org/10.2298/HEMIND110918074P . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Sabovljević, Marko
AU  - Tešević, Vele
AU  - Vajs, Vlatka
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2744
AB  - The identification of nystose and 1(F)-beta-fructofuranosylnystose in the oligosaccharide-rich fraction of the moss Rhodobryum ontariense (Kindb.) Kindb. (Bryaceae) by thin layer chromatography and high pressure chromatography with anion exchange-pulsed amperometric detector is discussed. According to our knowledge, it is the first record of these saccharides in the genus Rhodobryum as well as in the group of mosses as a whole. The findings are in good agreement with the recent isolation of 1-kestose from the same plant material and confirm that short-chain fructooligosaccharides, well known as prebiotics, are present in the examined bryophyte.
PB  - Adac-Cryptogamie, Paris
T2  - Cryptogamie Bryologie
T1  - Further study on fructooligosaccharides of Rhodobryum ontariense
VL  - 33
IS  - 2
SP  - 191
EP  - 196
DO  - 10.7872/cryb.v33.iss2.2012.191
ER  - 

@article{
author = "Pejin, Boris and Sabovljević, Marko and Tešević, Vele and Vajs, Vlatka",
year = "2012",
abstract = "The identification of nystose and 1(F)-beta-fructofuranosylnystose in the oligosaccharide-rich fraction of the moss Rhodobryum ontariense (Kindb.) Kindb. (Bryaceae) by thin layer chromatography and high pressure chromatography with anion exchange-pulsed amperometric detector is discussed. According to our knowledge, it is the first record of these saccharides in the genus Rhodobryum as well as in the group of mosses as a whole. The findings are in good agreement with the recent isolation of 1-kestose from the same plant material and confirm that short-chain fructooligosaccharides, well known as prebiotics, are present in the examined bryophyte.",
publisher = "Adac-Cryptogamie, Paris",
journal = "Cryptogamie Bryologie",
title = "Further study on fructooligosaccharides of Rhodobryum ontariense",
volume = "33",
number = "2",
pages = "191-196",
doi = "10.7872/cryb.v33.iss2.2012.191"
}

Pejin, B., Sabovljević, M., Tešević, V.,& Vajs, V.. (2012). Further study on fructooligosaccharides of Rhodobryum ontariense. in Cryptogamie Bryologie
Adac-Cryptogamie, Paris., 33(2), 191-196.
https://doi.org/10.7872/cryb.v33.iss2.2012.191

Pejin B, Sabovljević M, Tešević V, Vajs V. Further study on fructooligosaccharides of Rhodobryum ontariense. in Cryptogamie Bryologie. 2012;33(2):191-196.
doi:10.7872/cryb.v33.iss2.2012.191 .

Pejin, Boris, Sabovljević, Marko, Tešević, Vele, Vajs, Vlatka, "Further study on fructooligosaccharides of Rhodobryum ontariense" in Cryptogamie Bryologie, 33, no. 2 (2012):191-196,
https://doi.org/10.7872/cryb.v33.iss2.2012.191 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Tommonaro, Giuseppina
AU  - Iodice, Carmine
AU  - Tešević, Vele
AU  - Vajs, Vlatka
AU  - De Rosa, Salvatore
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4146
UR  - https://www.chalcogen.ro/1663_PEJIN.pdf
AB  - The continuation of our phytochemical survey of Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), has led to the isolation and identification of a new lichen depsidone (1) characterised by the normal analytical and spectroscopic techniques. Unlike previously isolated depsidone (2) from the same species, the compound 1 has not showed activity in the acetylcholinesterase inhibition test on Thin-layer chromatography plate.
PB  - Inst Materials Physics, Bucharest
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - A New Lichen Depsidone from  L Obaria Pulmonaria
VL  - 7
IS  - 4
SP  - 1663
EP  - 1666
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1566
ER  - 

@article{
author = "Pejin, Boris and Tommonaro, Giuseppina and Iodice, Carmine and Tešević, Vele and Vajs, Vlatka and De Rosa, Salvatore",
year = "2012",
abstract = "The continuation of our phytochemical survey of Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), has led to the isolation and identification of a new lichen depsidone (1) characterised by the normal analytical and spectroscopic techniques. Unlike previously isolated depsidone (2) from the same species, the compound 1 has not showed activity in the acetylcholinesterase inhibition test on Thin-layer chromatography plate.",
publisher = "Inst Materials Physics, Bucharest",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "A New Lichen Depsidone from  L Obaria Pulmonaria",
volume = "7",
number = "4",
pages = "1663-1666",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1566"
}

Pejin, B., Tommonaro, G., Iodice, C., Tešević, V., Vajs, V.,& De Rosa, S.. (2012). A New Lichen Depsidone from  L Obaria Pulmonaria. in Digest Journal of Nanomaterials and Biostructures
Inst Materials Physics, Bucharest., 7(4), 1663-1666.
https://hdl.handle.net/21.15107/rcub_cherry_1566

Pejin B, Tommonaro G, Iodice C, Tešević V, Vajs V, De Rosa S. A New Lichen Depsidone from  L Obaria Pulmonaria. in Digest Journal of Nanomaterials and Biostructures. 2012;7(4):1663-1666.
https://hdl.handle.net/21.15107/rcub_cherry_1566 .

Pejin, Boris, Tommonaro, Giuseppina, Iodice, Carmine, Tešević, Vele, Vajs, Vlatka, De Rosa, Salvatore, "A New Lichen Depsidone from  L Obaria Pulmonaria" in Digest Journal of Nanomaterials and Biostructures, 7, no. 4 (2012):1663-1666,
https://hdl.handle.net/21.15107/rcub_cherry_1566 .

TY  - JOUR
AU  - Pejin, Boris
AU  - Glamoclija, Jasmina
AU  - Ciric, Ana
AU  - Radotić, Ksenija
AU  - Vajs, Vlatka
AU  - Tešević, Vele
AU  - Hegedis, Aleksandar
AU  - Karaman, Ivo
AU  - Horvatovic, Mladen
AU  - Soković, Marina
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2737
AB  - The antimicrobial activity of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) was tested by microdilution method against eight bacteria and eight fungi for the first time. All five crude extracts (hexane, acetone, dimethyl sulfoxide, methanol and water) showed good antibacterial and antifungal potential in vitro wherein the acetone extract was the most active (MICs 0.50-7.00 mu g/ml and MBCs 2.50-10.00 mu g/ml).
PB  - Inst Materials Physics, Bucharest
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850)
VL  - 7
IS  - 3
SP  - 1021
EP  - 1026
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1565
ER  - 

@article{
author = "Pejin, Boris and Glamoclija, Jasmina and Ciric, Ana and Radotić, Ksenija and Vajs, Vlatka and Tešević, Vele and Hegedis, Aleksandar and Karaman, Ivo and Horvatovic, Mladen and Soković, Marina",
year = "2012",
abstract = "The antimicrobial activity of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) was tested by microdilution method against eight bacteria and eight fungi for the first time. All five crude extracts (hexane, acetone, dimethyl sulfoxide, methanol and water) showed good antibacterial and antifungal potential in vitro wherein the acetone extract was the most active (MICs 0.50-7.00 mu g/ml and MBCs 2.50-10.00 mu g/ml).",
publisher = "Inst Materials Physics, Bucharest",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850)",
volume = "7",
number = "3",
pages = "1021-1026",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1565"
}

Pejin, B., Glamoclija, J., Ciric, A., Radotić, K., Vajs, V., Tešević, V., Hegedis, A., Karaman, I., Horvatovic, M.,& Soković, M.. (2012). Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850). in Digest Journal of Nanomaterials and Biostructures
Inst Materials Physics, Bucharest., 7(3), 1021-1026.
https://hdl.handle.net/21.15107/rcub_cherry_1565

Pejin B, Glamoclija J, Ciric A, Radotić K, Vajs V, Tešević V, Hegedis A, Karaman I, Horvatovic M, Soković M. Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850). in Digest Journal of Nanomaterials and Biostructures. 2012;7(3):1021-1026.
https://hdl.handle.net/21.15107/rcub_cherry_1565 .

Pejin, Boris, Glamoclija, Jasmina, Ciric, Ana, Radotić, Ksenija, Vajs, Vlatka, Tešević, Vele, Hegedis, Aleksandar, Karaman, Ivo, Horvatovic, Mladen, Soković, Marina, "Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850)" in Digest Journal of Nanomaterials and Biostructures, 7, no. 3 (2012):1021-1026,
https://hdl.handle.net/21.15107/rcub_cherry_1565 .

TY  - JOUR
AU  - Bajic, Aleksandar
AU  - Zakrzewska, Joanna
AU  - Gođevac, Dejan
AU  - Anđus, Pavle
AU  - Jones, David R.
AU  - Spasić, Mihajlo
AU  - Spasojević, Ivan
PY  - 2011
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/781
AB  - The cytoprotective activity of F16BP has been documented in severe conditions such as convulsions, reperfusion injury, septic shock, diabetic complications, hypothermia-induced injury, UV-provoked skin damage and in other processes including apoptosis and excitotoxicity. F16BP shows very efficient cytoprotective activity in astroglial cells exposed to H2O2-provoked oxidative stress and during neuronal injury caused by hypoxic conditions. As most of the aforementioned processes involve iron activity-related conditions, we investigated the ferric and ferrous iron binding properties of F16BP under physiological conditions using P-31 NMR and EPR spectroscopy. Our results indicate that cytoprotective F16BP activity is predominantly based on ferrous iron sequestration. P-31 NMR spectroscopy of F16BP employing paramagnetic properties of iron clearly showed that F16BP forms stabile complexes with Fe2+ which was verified by EPR of another divalent cation-Mn2+. On the other hand, F16BP does not sequester ferric iron nor does it increase its redox activity as shown by P-31 NMR and EPR spin-trapping. Therefore, F16BP may be beneficial in neurodegenerative and other conditions that are characterised by ferric iron stores and deposits.
PB  - Elsevier Sci Ltd, Oxford
T2  - Carbohydrate Research
T1  - Relevance of the ability of fructose 1,6-bis(phosphate) to sequester ferrous but not ferric ions
VL  - 346
IS  - 3
SP  - 416
EP  - 420
DO  - 10.1016/j.carres.2010.12.008
ER  - 

@article{
author = "Bajic, Aleksandar and Zakrzewska, Joanna and Gođevac, Dejan and Anđus, Pavle and Jones, David R. and Spasić, Mihajlo and Spasojević, Ivan",
year = "2011",
abstract = "The cytoprotective activity of F16BP has been documented in severe conditions such as convulsions, reperfusion injury, septic shock, diabetic complications, hypothermia-induced injury, UV-provoked skin damage and in other processes including apoptosis and excitotoxicity. F16BP shows very efficient cytoprotective activity in astroglial cells exposed to H2O2-provoked oxidative stress and during neuronal injury caused by hypoxic conditions. As most of the aforementioned processes involve iron activity-related conditions, we investigated the ferric and ferrous iron binding properties of F16BP under physiological conditions using P-31 NMR and EPR spectroscopy. Our results indicate that cytoprotective F16BP activity is predominantly based on ferrous iron sequestration. P-31 NMR spectroscopy of F16BP employing paramagnetic properties of iron clearly showed that F16BP forms stabile complexes with Fe2+ which was verified by EPR of another divalent cation-Mn2+. On the other hand, F16BP does not sequester ferric iron nor does it increase its redox activity as shown by P-31 NMR and EPR spin-trapping. Therefore, F16BP may be beneficial in neurodegenerative and other conditions that are characterised by ferric iron stores and deposits.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Carbohydrate Research",
title = "Relevance of the ability of fructose 1,6-bis(phosphate) to sequester ferrous but not ferric ions",
volume = "346",
number = "3",
pages = "416-420",
doi = "10.1016/j.carres.2010.12.008"
}

Bajic, A., Zakrzewska, J., Gođevac, D., Anđus, P., Jones, D. R., Spasić, M.,& Spasojević, I.. (2011). Relevance of the ability of fructose 1,6-bis(phosphate) to sequester ferrous but not ferric ions. in Carbohydrate Research
Elsevier Sci Ltd, Oxford., 346(3), 416-420.
https://doi.org/10.1016/j.carres.2010.12.008

Bajic A, Zakrzewska J, Gođevac D, Anđus P, Jones DR, Spasić M, Spasojević I. Relevance of the ability of fructose 1,6-bis(phosphate) to sequester ferrous but not ferric ions. in Carbohydrate Research. 2011;346(3):416-420.
doi:10.1016/j.carres.2010.12.008 .

Bajic, Aleksandar, Zakrzewska, Joanna, Gođevac, Dejan, Anđus, Pavle, Jones, David R., Spasić, Mihajlo, Spasojević, Ivan, "Relevance of the ability of fructose 1,6-bis(phosphate) to sequester ferrous but not ferric ions" in Carbohydrate Research, 346, no. 3 (2011):416-420,
https://doi.org/10.1016/j.carres.2010.12.008 . .