TY  - JOUR
AU  - Mišković, Jovana
AU  - Karaman, Maja A.
AU  - Rašeta, Milena J.
AU  - Krsmanović, Nenad
AU  - Berežni, Sanja
AU  - Jakovljević, Dragica
AU  - Piattoni, Federica
AU  - Zambonelli, Alessandra
AU  - Gargano, Maria Letizia
AU  - Venturella, Giuseppe
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4338
AB  - In recent years, fungi have been recognized as producers of acetylcholinesterase (AChE) inhibitors, agents important for the prevention of Alzheimer’s disease (AD). This study aimed to examine the AChE inhibitory, the antioxidative and antibacterial activity of two different Schizophyllum commune strains that originated from Serbia (SRB) and Italy (IT). Submerged cultivation of grown mycelia (M) and fermentation broth (F) of ethanol (EtOH) and polysaccharide (PSH) extracts lasted for 7, 14, 21 and 28 days. For AChE activity Ellman method was performed, while for antioxidative activity, sevendifferent assays were conducted: DPPH, ABTS, FRAP, SOA, OH, NO together with total phenolic content. Antimicrobial screen, LC–MS/MS technique and FTIR measurements were performed. Different isolates exhibited different AChE activity, with PSH being the strongest (SRB, M, 28 days IC90 79.73 ± 26.34 µg/mL), while in EtOH extracts, IT stood out (F, 14 days, IC50 0.8 ± 0.6 µg/mL). PSH extracts (7 days) exhibit significant antioxidative activity (AO), opposite to EtOH extracts where 14 and 21days periods stood out. Only tw extracts showed antibacterial activity. Following LC–MS/MS analysis p-hydroxybenzoic and gallic acids were the most abundant phenolics. PSH extracts demonstrated remarkable results, making this study debut and introducing S. commune as a valuable resource of AChE inhibitors.
PB  - MDPI
T2  - Journal of Fungi
T1  - Comparison of two schizophyllum commune strains in production of acetylcholinesterase inhibitors and antioxidants from submerged cultivation
VL  - 7
IS  - 2
SP  - 115
EP  - 17
DO  - 10.3390/jof7020115
ER  - 

@article{
author = "Mišković, Jovana and Karaman, Maja A. and Rašeta, Milena J. and Krsmanović, Nenad and Berežni, Sanja and Jakovljević, Dragica and Piattoni, Federica and Zambonelli, Alessandra and Gargano, Maria Letizia and Venturella, Giuseppe",
year = "2021",
abstract = "In recent years, fungi have been recognized as producers of acetylcholinesterase (AChE) inhibitors, agents important for the prevention of Alzheimer’s disease (AD). This study aimed to examine the AChE inhibitory, the antioxidative and antibacterial activity of two different Schizophyllum commune strains that originated from Serbia (SRB) and Italy (IT). Submerged cultivation of grown mycelia (M) and fermentation broth (F) of ethanol (EtOH) and polysaccharide (PSH) extracts lasted for 7, 14, 21 and 28 days. For AChE activity Ellman method was performed, while for antioxidative activity, sevendifferent assays were conducted: DPPH, ABTS, FRAP, SOA, OH, NO together with total phenolic content. Antimicrobial screen, LC–MS/MS technique and FTIR measurements were performed. Different isolates exhibited different AChE activity, with PSH being the strongest (SRB, M, 28 days IC90 79.73 ± 26.34 µg/mL), while in EtOH extracts, IT stood out (F, 14 days, IC50 0.8 ± 0.6 µg/mL). PSH extracts (7 days) exhibit significant antioxidative activity (AO), opposite to EtOH extracts where 14 and 21days periods stood out. Only tw extracts showed antibacterial activity. Following LC–MS/MS analysis p-hydroxybenzoic and gallic acids were the most abundant phenolics. PSH extracts demonstrated remarkable results, making this study debut and introducing S. commune as a valuable resource of AChE inhibitors.",
publisher = "MDPI",
journal = "Journal of Fungi",
title = "Comparison of two schizophyllum commune strains in production of acetylcholinesterase inhibitors and antioxidants from submerged cultivation",
volume = "7",
number = "2",
pages = "115-17",
doi = "10.3390/jof7020115"
}

Mišković, J., Karaman, M. A., Rašeta, M. J., Krsmanović, N., Berežni, S., Jakovljević, D., Piattoni, F., Zambonelli, A., Gargano, M. L.,& Venturella, G.. (2021). Comparison of two schizophyllum commune strains in production of acetylcholinesterase inhibitors and antioxidants from submerged cultivation. in Journal of Fungi
MDPI., 7(2), 115-17.
https://doi.org/10.3390/jof7020115

Mišković J, Karaman MA, Rašeta MJ, Krsmanović N, Berežni S, Jakovljević D, Piattoni F, Zambonelli A, Gargano ML, Venturella G. Comparison of two schizophyllum commune strains in production of acetylcholinesterase inhibitors and antioxidants from submerged cultivation. in Journal of Fungi. 2021;7(2):115-17.
doi:10.3390/jof7020115 .

Mišković, Jovana, Karaman, Maja A., Rašeta, Milena J., Krsmanović, Nenad, Berežni, Sanja, Jakovljević, Dragica, Piattoni, Federica, Zambonelli, Alessandra, Gargano, Maria Letizia, Venturella, Giuseppe, "Comparison of two schizophyllum commune strains in production of acetylcholinesterase inhibitors and antioxidants from submerged cultivation" in Journal of Fungi, 7, no. 2 (2021):115-17,
https://doi.org/10.3390/jof7020115 . .

TY  - JOUR
AU  - Đurašević, Siniša
AU  - Nikolić, Gorana
AU  - Todorović, Ana
AU  - Drakulić, Dunja
AU  - Pejić, Snežana
AU  - Martinović, Vesna
AU  - Mitić-Ćulafić, Dragana
AU  - Milić, Dragana
AU  - Kop, Tatjana
AU  - Jasnić, Nebojša
AU  - Đorđević, Jelena
AU  - Todorović, Zoran
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3488
AB  - The effects of twelve weeks of supplementation with fullerene C60 olive/coconut oil solution on a broad spectrum of parameters in rats were examined. The tissue bioaccumulation of C60 was shown to be tissue-specific, with the liver, heart, and adrenal glands being the organs of the greatest, and the kidney, brain, and spleen being the organs of the smallest accumulation. C60 did not change aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase serum activities level, nor the damage of liver cells DNA. There were no effects of fullerene on prooxidant-antioxidant balance in the liver, kidney, spleen, heart, and brain, nor any visible harmful effects on the liver, heart, aorta, spleen, kidney, and small intestine histology. Fullerene changed the gut microbiota structure towards the bacteria that ameliorate lipid homeostasis, causing a serum triglycerides concentration decrease. However, C60 significantly increased the insulin resistance, serum ascorbate oxidation, and brain malondialdehyde and advanced oxidation protein products level. The deteriorative effects of C60 on the brain and serum could be attributed to the specific physicochemical composition of these tissues, potentiating the C60 aggregation or biotransformation as the key element of its pro-oxidative action.
PB  - Elsevier
T2  - Food and Chemical Toxicology
T1  - Effects of fullerene C60 supplementation on gut microbiota and glucose and lipid homeostasis in rats
VL  - 140
SP  - 111322
DO  - 10.1016/j.fct.2020.111302
ER  - 

@article{
author = "Đurašević, Siniša and Nikolić, Gorana and Todorović, Ana and Drakulić, Dunja and Pejić, Snežana and Martinović, Vesna and Mitić-Ćulafić, Dragana and Milić, Dragana and Kop, Tatjana and Jasnić, Nebojša and Đorđević, Jelena and Todorović, Zoran",
year = "2020",
abstract = "The effects of twelve weeks of supplementation with fullerene C60 olive/coconut oil solution on a broad spectrum of parameters in rats were examined. The tissue bioaccumulation of C60 was shown to be tissue-specific, with the liver, heart, and adrenal glands being the organs of the greatest, and the kidney, brain, and spleen being the organs of the smallest accumulation. C60 did not change aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase serum activities level, nor the damage of liver cells DNA. There were no effects of fullerene on prooxidant-antioxidant balance in the liver, kidney, spleen, heart, and brain, nor any visible harmful effects on the liver, heart, aorta, spleen, kidney, and small intestine histology. Fullerene changed the gut microbiota structure towards the bacteria that ameliorate lipid homeostasis, causing a serum triglycerides concentration decrease. However, C60 significantly increased the insulin resistance, serum ascorbate oxidation, and brain malondialdehyde and advanced oxidation protein products level. The deteriorative effects of C60 on the brain and serum could be attributed to the specific physicochemical composition of these tissues, potentiating the C60 aggregation or biotransformation as the key element of its pro-oxidative action.",
publisher = "Elsevier",
journal = "Food and Chemical Toxicology",
title = "Effects of fullerene C60 supplementation on gut microbiota and glucose and lipid homeostasis in rats",
volume = "140",
pages = "111322",
doi = "10.1016/j.fct.2020.111302"
}

Đurašević, S., Nikolić, G., Todorović, A., Drakulić, D., Pejić, S., Martinović, V., Mitić-Ćulafić, D., Milić, D., Kop, T., Jasnić, N., Đorđević, J.,& Todorović, Z.. (2020). Effects of fullerene C60 supplementation on gut microbiota and glucose and lipid homeostasis in rats. in Food and Chemical Toxicology
Elsevier., 140, 111322.
https://doi.org/10.1016/j.fct.2020.111302

Đurašević S, Nikolić G, Todorović A, Drakulić D, Pejić S, Martinović V, Mitić-Ćulafić D, Milić D, Kop T, Jasnić N, Đorđević J, Todorović Z. Effects of fullerene C60 supplementation on gut microbiota and glucose and lipid homeostasis in rats. in Food and Chemical Toxicology. 2020;140:111322.
doi:10.1016/j.fct.2020.111302 .

Đurašević, Siniša, Nikolić, Gorana, Todorović, Ana, Drakulić, Dunja, Pejić, Snežana, Martinović, Vesna, Mitić-Ćulafić, Dragana, Milić, Dragana, Kop, Tatjana, Jasnić, Nebojša, Đorđević, Jelena, Todorović, Zoran, "Effects of fullerene C60 supplementation on gut microbiota and glucose and lipid homeostasis in rats" in Food and Chemical Toxicology, 140 (2020):111322,
https://doi.org/10.1016/j.fct.2020.111302 . .

TY  - JOUR
AU  - Đorđević, J.
AU  - Kolarević, S.
AU  - Jovanović, J.
AU  - Kostić-Vuković, J.
AU  - Novaković, Irena
AU  - Jeremić, M.
AU  - Sladić, Dušan
AU  - Vuković-Gačić, Branka
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2415
AB  - Tert-butylquinone (TBQ) and its alkylamino and aralkylamino derivatives are of high interest as a potential antitumor agent. Therefore, it was necessary to investigate if the compounds exert undesirable activities such as interaction with DNA molecule which could result in negative side effects in the case of their use in the diseases treatment. The major aim of this study was to investigate genotoxic potential of TBQ and selected derivatives in an acellular model by using plasmid DNA, in the prokaryotic model by the SOS/umuC assay in Salmonella typhimurium TA1535/pSK1002 and in eukaryotic models by using comet assay in human fetal lung cell line (MRC-5) and human liver cancer cell line (HepG2). Results indicated that in the acellular model TBQ and its derivatives do not interact with plasmid pUC19. In the prokaryotic model, only TBQ exerted weak genotoxic potential and only at highly cytotoxic concentrations. In eukaryotic models, genotoxic potential was detected mainly at the highest concentrations of the tested substances but the effect was lower in both cell lines in comparison with benzo[a]pyrene and etoposide which were used as positive controls. Weak genotoxic potential of tested compounds recommends them as good candidates for further testing in development of new antitumor agents.
PB  - Taylor and Francis Ltd
T2  - Drug and Chemical Toxicology
T1  - Evaluation of genotoxic potential of tert-butylquinone and its derivatives in prokaryotic and eukaryotic test models
SP  - 522
EP  - 530
DO  - 10.1080/01480545.2018.1514043
ER  - 

@article{
author = "Đorđević, J. and Kolarević, S. and Jovanović, J. and Kostić-Vuković, J. and Novaković, Irena and Jeremić, M. and Sladić, Dušan and Vuković-Gačić, Branka",
year = "2018",
abstract = "Tert-butylquinone (TBQ) and its alkylamino and aralkylamino derivatives are of high interest as a potential antitumor agent. Therefore, it was necessary to investigate if the compounds exert undesirable activities such as interaction with DNA molecule which could result in negative side effects in the case of their use in the diseases treatment. The major aim of this study was to investigate genotoxic potential of TBQ and selected derivatives in an acellular model by using plasmid DNA, in the prokaryotic model by the SOS/umuC assay in Salmonella typhimurium TA1535/pSK1002 and in eukaryotic models by using comet assay in human fetal lung cell line (MRC-5) and human liver cancer cell line (HepG2). Results indicated that in the acellular model TBQ and its derivatives do not interact with plasmid pUC19. In the prokaryotic model, only TBQ exerted weak genotoxic potential and only at highly cytotoxic concentrations. In eukaryotic models, genotoxic potential was detected mainly at the highest concentrations of the tested substances but the effect was lower in both cell lines in comparison with benzo[a]pyrene and etoposide which were used as positive controls. Weak genotoxic potential of tested compounds recommends them as good candidates for further testing in development of new antitumor agents.",
publisher = "Taylor and Francis Ltd",
journal = "Drug and Chemical Toxicology",
title = "Evaluation of genotoxic potential of tert-butylquinone and its derivatives in prokaryotic and eukaryotic test models",
pages = "522-530",
doi = "10.1080/01480545.2018.1514043"
}

Đorđević, J., Kolarević, S., Jovanović, J., Kostić-Vuković, J., Novaković, I., Jeremić, M., Sladić, D.,& Vuković-Gačić, B.. (2018). Evaluation of genotoxic potential of tert-butylquinone and its derivatives in prokaryotic and eukaryotic test models. in Drug and Chemical Toxicology
Taylor and Francis Ltd., 522-530.
https://doi.org/10.1080/01480545.2018.1514043

Đorđević J, Kolarević S, Jovanović J, Kostić-Vuković J, Novaković I, Jeremić M, Sladić D, Vuković-Gačić B. Evaluation of genotoxic potential of tert-butylquinone and its derivatives in prokaryotic and eukaryotic test models. in Drug and Chemical Toxicology. 2018;:522-530.
doi:10.1080/01480545.2018.1514043 .

Đorđević, J., Kolarević, S., Jovanović, J., Kostić-Vuković, J., Novaković, Irena, Jeremić, M., Sladić, Dušan, Vuković-Gačić, Branka, "Evaluation of genotoxic potential of tert-butylquinone and its derivatives in prokaryotic and eukaryotic test models" in Drug and Chemical Toxicology (2018):522-530,
https://doi.org/10.1080/01480545.2018.1514043 . .

TY  - JOUR
AU  - Karaman, M.
AU  - Tesanovic, K.
AU  - Novakovic, A.
AU  - Jakovljević, Dragica
AU  - Janjusevic, L.
AU  - Sibul, F.
AU  - Pejin, Boris
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2388
AB  - In vitro acetylholinesterase (AChE) inhibitory activity of an autochthonous sample of the mushroom Coprinus comatus (encompassing fruiting body FB, mycelia M and filtrate F from the submerged cultivation) was the subject of this study. C. comatus F extract exhibited rather potent anti-AChE activity (73.0 ± 1.5%) at in liquid conditions, comparable to those of the conventional drug donepezil (80.6 ± 1.4%). Also, the same extract exhibited high anti-AChE activity (1 µg) in solid. While its FTIR spectrum indicated the presence of phenolic compounds, quercetin (28.1 µg g−1 d.w.) was found to affect the observed bioactivity (59.8 ± 0.9%). This is the first report of profound anti-AChE activity of any C. comatus extract, a medicinal mushroom that has been successfully cultivated in P.R. China, due to the demanding needs of food industry.
PB  - Taylor and Francis Ltd.
T2  - Natural Product Research
T1  - Coprinus comatus filtrate extract, a novel neuroprotective agent of natural origin
VL  - 34
IS  - 16
SP  - 2346
EP  - 2350
DO  - 10.1080/14786419.2018.1533831
ER  - 

@article{
author = "Karaman, M. and Tesanovic, K. and Novakovic, A. and Jakovljević, Dragica and Janjusevic, L. and Sibul, F. and Pejin, Boris",
year = "2018",
abstract = "In vitro acetylholinesterase (AChE) inhibitory activity of an autochthonous sample of the mushroom Coprinus comatus (encompassing fruiting body FB, mycelia M and filtrate F from the submerged cultivation) was the subject of this study. C. comatus F extract exhibited rather potent anti-AChE activity (73.0 ± 1.5%) at in liquid conditions, comparable to those of the conventional drug donepezil (80.6 ± 1.4%). Also, the same extract exhibited high anti-AChE activity (1 µg) in solid. While its FTIR spectrum indicated the presence of phenolic compounds, quercetin (28.1 µg g−1 d.w.) was found to affect the observed bioactivity (59.8 ± 0.9%). This is the first report of profound anti-AChE activity of any C. comatus extract, a medicinal mushroom that has been successfully cultivated in P.R. China, due to the demanding needs of food industry.",
publisher = "Taylor and Francis Ltd.",
journal = "Natural Product Research",
title = "Coprinus comatus filtrate extract, a novel neuroprotective agent of natural origin",
volume = "34",
number = "16",
pages = "2346-2350",
doi = "10.1080/14786419.2018.1533831"
}

Karaman, M., Tesanovic, K., Novakovic, A., Jakovljević, D., Janjusevic, L., Sibul, F.,& Pejin, B.. (2018). Coprinus comatus filtrate extract, a novel neuroprotective agent of natural origin. in Natural Product Research
Taylor and Francis Ltd.., 34(16), 2346-2350.
https://doi.org/10.1080/14786419.2018.1533831

Karaman M, Tesanovic K, Novakovic A, Jakovljević D, Janjusevic L, Sibul F, Pejin B. Coprinus comatus filtrate extract, a novel neuroprotective agent of natural origin. in Natural Product Research. 2018;34(16):2346-2350.
doi:10.1080/14786419.2018.1533831 .

Karaman, M., Tesanovic, K., Novakovic, A., Jakovljević, Dragica, Janjusevic, L., Sibul, F., Pejin, Boris, "Coprinus comatus filtrate extract, a novel neuroprotective agent of natural origin" in Natural Product Research, 34, no. 16 (2018):2346-2350,
https://doi.org/10.1080/14786419.2018.1533831 . .

TY  - JOUR
AU  - Marin, Marija
AU  - Novaković, Miroslav
AU  - Vučković, Ivan
AU  - Tešević, Vele
AU  - Kolarevic, Stoimir
AU  - Vukovic-Gacic, Branka
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2314
AB  - The composition of the essential oil (EO) obtained by hydrodistillation from the leaves of Thymus capitatus Hoff. et Link. growing wild in Sythonia (Greece) was analysed by GC-FID, GC-MS and quantitative H-1 NMR spectroscopy. Thirty nine compounds were identified, representing approximately 99.0 % of the oil. Major component determined by GC-FID was carvacrol (81.8 %), followed by linalool (3.5 %) and (E)-caryophyllenc (3.5 %). Abundance of carvacrol determined by quantitative H-1 NMR spectroscopy was 74.9 % and was in reasonable agreement with GC-FID result. The oil was tested for the antioxidant activity in DPPH assay and showed a dose dependent free radical scavenging activity with EC50 value of 1.03 mu g/ml. Antimicrobial effect of the EO was tested against Gram negative, Gram positive bacteria, and fungi. The tested EO showed significant activity against fungi, especially S. cerevisiae. The most sensitive bacteria were E. coil ATCC 25922, E. fecalis and S. epidermidis. Human pathogen Burkholderia cepacia, ATCC 25416 was used in the investigation of T capitatus for the fast time.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Journal of Essential Oil Bearing Plants
T1  - Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil
VL  - 21
IS  - 2
SP  - 388
EP  - 399
DO  - 10.1080/0972060X.2018.1449668
ER  - 

@article{
author = "Marin, Marija and Novaković, Miroslav and Vučković, Ivan and Tešević, Vele and Kolarevic, Stoimir and Vukovic-Gacic, Branka",
year = "2018",
abstract = "The composition of the essential oil (EO) obtained by hydrodistillation from the leaves of Thymus capitatus Hoff. et Link. growing wild in Sythonia (Greece) was analysed by GC-FID, GC-MS and quantitative H-1 NMR spectroscopy. Thirty nine compounds were identified, representing approximately 99.0 % of the oil. Major component determined by GC-FID was carvacrol (81.8 %), followed by linalool (3.5 %) and (E)-caryophyllenc (3.5 %). Abundance of carvacrol determined by quantitative H-1 NMR spectroscopy was 74.9 % and was in reasonable agreement with GC-FID result. The oil was tested for the antioxidant activity in DPPH assay and showed a dose dependent free radical scavenging activity with EC50 value of 1.03 mu g/ml. Antimicrobial effect of the EO was tested against Gram negative, Gram positive bacteria, and fungi. The tested EO showed significant activity against fungi, especially S. cerevisiae. The most sensitive bacteria were E. coil ATCC 25922, E. fecalis and S. epidermidis. Human pathogen Burkholderia cepacia, ATCC 25416 was used in the investigation of T capitatus for the fast time.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Journal of Essential Oil Bearing Plants",
title = "Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil",
volume = "21",
number = "2",
pages = "388-399",
doi = "10.1080/0972060X.2018.1449668"
}

Marin, M., Novaković, M., Vučković, I., Tešević, V., Kolarevic, S.,& Vukovic-Gacic, B.. (2018). Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil. in Journal of Essential Oil Bearing Plants
Taylor & Francis Ltd, Abingdon., 21(2), 388-399.
https://doi.org/10.1080/0972060X.2018.1449668

Marin M, Novaković M, Vučković I, Tešević V, Kolarevic S, Vukovic-Gacic B. Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil. in Journal of Essential Oil Bearing Plants. 2018;21(2):388-399.
doi:10.1080/0972060X.2018.1449668 .

Marin, Marija, Novaković, Miroslav, Vučković, Ivan, Tešević, Vele, Kolarevic, Stoimir, Vukovic-Gacic, Branka, "Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil" in Journal of Essential Oil Bearing Plants, 21, no. 2 (2018):388-399,
https://doi.org/10.1080/0972060X.2018.1449668 . .

TY  - JOUR
AU  - Marin, Marija
AU  - Novaković, Miroslav
AU  - Tešević, Vele
AU  - Kolarevic, Stoimir
AU  - Vukovic-Gacic, Branka
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2378
AB  - In this study, we compared the compositions, antimicrobial and potential antioxidant activities of essential oils of two Thymus endemic, wild-growing species - T. malyi Ronninger and T. lykae Degen et Jay. No information about its composition and biological activities of oils has been reported to the present day. Forty three compounds were identified from T. malyi and major component was a-pinene (26.4%). In the case of T. lykae, forty four compounds were identified, with geranyl acetate (35.1%) as the main component. Antioxidant activities of the oils were evaluated using DPPH assay. The antimicrobial effect of essential oils were tested against Gram-negative, Gram-positive bacteria, and two fungi. Results indicated higher antibacterial activity of the essential oils of T. lykae in comparison with T. malyi, while for antifungal activity, it was reverse. The essential oils from T. malyi and T. lykae possess antioxidant and antimicrobial activities and could be used as a potential source of natural antioxidants for the food industry.
PB  - Wydawnictwo Akad Rolniczej W Lublinie, Lublin
T2  - Acta Scientiarum Polonorum-Hortorum Cultus
T1  - Comparision of the compositions, antimicrobial and antioxidant activities of essential oils from the endemic species thymus malyi ronninger and thymus lykae degen et jav.
VL  - 17
IS  - 5
SP  - 157
EP  - 165
DO  - 10.24326/asphc.2018.5.14
ER  - 

@article{
author = "Marin, Marija and Novaković, Miroslav and Tešević, Vele and Kolarevic, Stoimir and Vukovic-Gacic, Branka",
year = "2018",
abstract = "In this study, we compared the compositions, antimicrobial and potential antioxidant activities of essential oils of two Thymus endemic, wild-growing species - T. malyi Ronninger and T. lykae Degen et Jay. No information about its composition and biological activities of oils has been reported to the present day. Forty three compounds were identified from T. malyi and major component was a-pinene (26.4%). In the case of T. lykae, forty four compounds were identified, with geranyl acetate (35.1%) as the main component. Antioxidant activities of the oils were evaluated using DPPH assay. The antimicrobial effect of essential oils were tested against Gram-negative, Gram-positive bacteria, and two fungi. Results indicated higher antibacterial activity of the essential oils of T. lykae in comparison with T. malyi, while for antifungal activity, it was reverse. The essential oils from T. malyi and T. lykae possess antioxidant and antimicrobial activities and could be used as a potential source of natural antioxidants for the food industry.",
publisher = "Wydawnictwo Akad Rolniczej W Lublinie, Lublin",
journal = "Acta Scientiarum Polonorum-Hortorum Cultus",
title = "Comparision of the compositions, antimicrobial and antioxidant activities of essential oils from the endemic species thymus malyi ronninger and thymus lykae degen et jav.",
volume = "17",
number = "5",
pages = "157-165",
doi = "10.24326/asphc.2018.5.14"
}

Marin, M., Novaković, M., Tešević, V., Kolarevic, S.,& Vukovic-Gacic, B.. (2018). Comparision of the compositions, antimicrobial and antioxidant activities of essential oils from the endemic species thymus malyi ronninger and thymus lykae degen et jav.. in Acta Scientiarum Polonorum-Hortorum Cultus
Wydawnictwo Akad Rolniczej W Lublinie, Lublin., 17(5), 157-165.
https://doi.org/10.24326/asphc.2018.5.14

Marin M, Novaković M, Tešević V, Kolarevic S, Vukovic-Gacic B. Comparision of the compositions, antimicrobial and antioxidant activities of essential oils from the endemic species thymus malyi ronninger and thymus lykae degen et jav.. in Acta Scientiarum Polonorum-Hortorum Cultus. 2018;17(5):157-165.
doi:10.24326/asphc.2018.5.14 .

Marin, Marija, Novaković, Miroslav, Tešević, Vele, Kolarevic, Stoimir, Vukovic-Gacic, Branka, "Comparision of the compositions, antimicrobial and antioxidant activities of essential oils from the endemic species thymus malyi ronninger and thymus lykae degen et jav." in Acta Scientiarum Polonorum-Hortorum Cultus, 17, no. 5 (2018):157-165,
https://doi.org/10.24326/asphc.2018.5.14 . .

TY  - JOUR
AU  - Kolarević, Stoimir M.
AU  - Milovanović, Dragana
AU  - Kračun-Kolarević, Margareta
AU  - Kostić, Jovana
AU  - Sunjog, K.
AU  - Martinović, Rajko
AU  - Đorđević, Jelena
AU  - Novaković, Irena
AU  - Sladić, Dušan
AU  - Vuković-Gačić, Branka
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2232
AB  - In this study, mutagenic and genotoxic potential of anti-tumor compounds avarol, avarone, and its derivatives 3′-methoxyavarone, 4′-(methylamino)avarone and 3′-(methylamino)avarone was evaluated and compared to cytostatics commonly used in chemotherapy (5-fluorouracil, etoposid, and cisplatin). Mutagenic potential of selected hydroquinone and quinones was assessed in prokaryotic model by the SOS/umuC assay in Salmonella typhimurium TA1535/pSK1002. Genotoxic potential was also assessed in eukaryotic models using comet assay in human fetal lung cell line (MRC-5), human adenocarcinoma epithelial cell line (A549), and in human peripheral blood cells (HPBC). The results indicated that avarol and avarone do not exert mutagenic/genotoxic potential. Among the studied avarone derivatives, mutagenic potential was detected by SOS/umuC test for 3′-(methylamino)avarone, but only after metabolic activation. The results of comet assay indicated that 3′-methoxyavarone and 3′-(methylamino)avarone have a significant impact on the level of DNA damage in the MRC-5 cell line. Genotoxic potential was not observed in A549 cells or HPBC probably due to a different uptake rate for the compounds and lower in metabolism rate within these cells.
PB  - Taylor and Francis Ltd
T2  - Drug and Chemical Toxicology
T1  - Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models
SP  - 1
EP  - 10
DO  - 10.1080/01480545.2017.1413108
ER  - 

@article{
author = "Kolarević, Stoimir M. and Milovanović, Dragana and Kračun-Kolarević, Margareta and Kostić, Jovana and Sunjog, K. and Martinović, Rajko and Đorđević, Jelena and Novaković, Irena and Sladić, Dušan and Vuković-Gačić, Branka",
year = "2017",
abstract = "In this study, mutagenic and genotoxic potential of anti-tumor compounds avarol, avarone, and its derivatives 3′-methoxyavarone, 4′-(methylamino)avarone and 3′-(methylamino)avarone was evaluated and compared to cytostatics commonly used in chemotherapy (5-fluorouracil, etoposid, and cisplatin). Mutagenic potential of selected hydroquinone and quinones was assessed in prokaryotic model by the SOS/umuC assay in Salmonella typhimurium TA1535/pSK1002. Genotoxic potential was also assessed in eukaryotic models using comet assay in human fetal lung cell line (MRC-5), human adenocarcinoma epithelial cell line (A549), and in human peripheral blood cells (HPBC). The results indicated that avarol and avarone do not exert mutagenic/genotoxic potential. Among the studied avarone derivatives, mutagenic potential was detected by SOS/umuC test for 3′-(methylamino)avarone, but only after metabolic activation. The results of comet assay indicated that 3′-methoxyavarone and 3′-(methylamino)avarone have a significant impact on the level of DNA damage in the MRC-5 cell line. Genotoxic potential was not observed in A549 cells or HPBC probably due to a different uptake rate for the compounds and lower in metabolism rate within these cells.",
publisher = "Taylor and Francis Ltd",
journal = "Drug and Chemical Toxicology",
title = "Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models",
pages = "1-10",
doi = "10.1080/01480545.2017.1413108"
}

Kolarević, S. M., Milovanović, D., Kračun-Kolarević, M., Kostić, J., Sunjog, K., Martinović, R., Đorđević, J., Novaković, I., Sladić, D.,& Vuković-Gačić, B.. (2017). Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models. in Drug and Chemical Toxicology
Taylor and Francis Ltd., 1-10.
https://doi.org/10.1080/01480545.2017.1413108

Kolarević SM, Milovanović D, Kračun-Kolarević M, Kostić J, Sunjog K, Martinović R, Đorđević J, Novaković I, Sladić D, Vuković-Gačić B. Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models. in Drug and Chemical Toxicology. 2017;:1-10.
doi:10.1080/01480545.2017.1413108 .

Kolarević, Stoimir M., Milovanović, Dragana, Kračun-Kolarević, Margareta, Kostić, Jovana, Sunjog, K., Martinović, Rajko, Đorđević, Jelena, Novaković, Irena, Sladić, Dušan, Vuković-Gačić, Branka, "Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models" in Drug and Chemical Toxicology (2017):1-10,
https://doi.org/10.1080/01480545.2017.1413108 . .

TY  - JOUR
AU  - Janjusevic, Ljiljana
AU  - Karaman, Maja
AU  - Sibul, Filip
AU  - Tommonaro, Giuseppina
AU  - Iodice, Carmine
AU  - Jakovljević, Dragica
AU  - Pejin, Boris
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2062
AB  - This study aimed to determine antiradical (DPPH center dot and (OH)-O-center dot) and acetylcholinesterase (AChE) inhibitory activities along with chemical composition of autochtonous fungal species Trametes versicolor (Serbia). A total of 38 phenolic compounds with notable presence of phenolic acids were identified using HPLC/MS-MS. Its water extract exhibited the highest antiradical activity against (OH)-O-center dot (3.21 mu g/mL), among the rest due to the presence of gallic, p-coumaric and caffeic acids. At the concentration of 100 mu g/mL, the same extract displayed a profound AChE inhibitory activity (60.53%) in liquid, compared to donepezil (89.05%), a drug in clinical practice used as positive control. The flavonoids baicalein and quercetin may be responsible compounds for the AChE inhibitory activity observed. These findings have demonstrated considerable potential of T. versicolor water extract as a natural source of antioxidant(s) and/or AChE inhibitor(s) to be eventually used as drug-like compounds or food supplements in the treatment of Alzheimer's disease.
PB  - Taylor & Francis Group
T2  - Journal of Enzyme Inhibition and Medicinal Chemistry
T1  - The lignicolous fungus Trametes versicolor (L.) Lloyd (1920): a promising natural source of antiradical and AChE inhibitory agents
VL  - 32
IS  - 1
SP  - 355
EP  - 362
DO  - 10.1080/14756366.2016.1252759
ER  - 

@article{
author = "Janjusevic, Ljiljana and Karaman, Maja and Sibul, Filip and Tommonaro, Giuseppina and Iodice, Carmine and Jakovljević, Dragica and Pejin, Boris",
year = "2017",
abstract = "This study aimed to determine antiradical (DPPH center dot and (OH)-O-center dot) and acetylcholinesterase (AChE) inhibitory activities along with chemical composition of autochtonous fungal species Trametes versicolor (Serbia). A total of 38 phenolic compounds with notable presence of phenolic acids were identified using HPLC/MS-MS. Its water extract exhibited the highest antiradical activity against (OH)-O-center dot (3.21 mu g/mL), among the rest due to the presence of gallic, p-coumaric and caffeic acids. At the concentration of 100 mu g/mL, the same extract displayed a profound AChE inhibitory activity (60.53%) in liquid, compared to donepezil (89.05%), a drug in clinical practice used as positive control. The flavonoids baicalein and quercetin may be responsible compounds for the AChE inhibitory activity observed. These findings have demonstrated considerable potential of T. versicolor water extract as a natural source of antioxidant(s) and/or AChE inhibitor(s) to be eventually used as drug-like compounds or food supplements in the treatment of Alzheimer's disease.",
publisher = "Taylor & Francis Group",
journal = "Journal of Enzyme Inhibition and Medicinal Chemistry",
title = "The lignicolous fungus Trametes versicolor (L.) Lloyd (1920): a promising natural source of antiradical and AChE inhibitory agents",
volume = "32",
number = "1",
pages = "355-362",
doi = "10.1080/14756366.2016.1252759"
}

Janjusevic, L., Karaman, M., Sibul, F., Tommonaro, G., Iodice, C., Jakovljević, D.,& Pejin, B.. (2017). The lignicolous fungus Trametes versicolor (L.) Lloyd (1920): a promising natural source of antiradical and AChE inhibitory agents. in Journal of Enzyme Inhibition and Medicinal Chemistry
Taylor & Francis Group., 32(1), 355-362.
https://doi.org/10.1080/14756366.2016.1252759

Janjusevic L, Karaman M, Sibul F, Tommonaro G, Iodice C, Jakovljević D, Pejin B. The lignicolous fungus Trametes versicolor (L.) Lloyd (1920): a promising natural source of antiradical and AChE inhibitory agents. in Journal of Enzyme Inhibition and Medicinal Chemistry. 2017;32(1):355-362.
doi:10.1080/14756366.2016.1252759 .

Janjusevic, Ljiljana, Karaman, Maja, Sibul, Filip, Tommonaro, Giuseppina, Iodice, Carmine, Jakovljević, Dragica, Pejin, Boris, "The lignicolous fungus Trametes versicolor (L.) Lloyd (1920): a promising natural source of antiradical and AChE inhibitory agents" in Journal of Enzyme Inhibition and Medicinal Chemistry, 32, no. 1 (2017):355-362,
https://doi.org/10.1080/14756366.2016.1252759 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Tešanović, K.
AU  - Jakovljević, Dragica
AU  - Kaišarević, S.
AU  - Šibul, F.
AU  - Rašeta, M.
AU  - Karaman, M.
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2226
AB  - The polysaccharide (PSH) extracts from the edible mushroom species Coprinus comatus and Coprinellus truncorum were screened in liquid for their acetylcholinesterase inhibitory (AChE) activity. Both extracts were found to display inhibition of the aforementioned enzyme reaching similar IC50 values of 0.62 ± 0.07 and 0.61 ± 0.03 mg/mL, respectively. According to the means of FTIR spectroscopy, these PSH extracts mostly contained β-glucans. However, the presence of some proteins and polyphenolics as minor ingredients were also detected. Compared with existing literature data for anti-AChE activity of the sugar samples, the findings within this study may be treated as a profound bioactivity. Consequently, this study puts some light on the possible use of the screened macrofungi in the palliative treatment of Alzheimer’s disease.
PB  - Taylor and Francis Ltd.
T2  - Natural Product Research
T1  - The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity
SP  - 1
EP  - 5
DO  - 10.1080/14786419.2017.1405417
ER  - 

@article{
author = "Pejin, Boris and Tešanović, K. and Jakovljević, Dragica and Kaišarević, S. and Šibul, F. and Rašeta, M. and Karaman, M.",
year = "2017",
abstract = "The polysaccharide (PSH) extracts from the edible mushroom species Coprinus comatus and Coprinellus truncorum were screened in liquid for their acetylcholinesterase inhibitory (AChE) activity. Both extracts were found to display inhibition of the aforementioned enzyme reaching similar IC50 values of 0.62 ± 0.07 and 0.61 ± 0.03 mg/mL, respectively. According to the means of FTIR spectroscopy, these PSH extracts mostly contained β-glucans. However, the presence of some proteins and polyphenolics as minor ingredients were also detected. Compared with existing literature data for anti-AChE activity of the sugar samples, the findings within this study may be treated as a profound bioactivity. Consequently, this study puts some light on the possible use of the screened macrofungi in the palliative treatment of Alzheimer’s disease.",
publisher = "Taylor and Francis Ltd.",
journal = "Natural Product Research",
title = "The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity",
pages = "1-5",
doi = "10.1080/14786419.2017.1405417"
}

Pejin, B., Tešanović, K., Jakovljević, D., Kaišarević, S., Šibul, F., Rašeta, M.,& Karaman, M.. (2017). The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity. in Natural Product Research
Taylor and Francis Ltd.., 1-5.
https://doi.org/10.1080/14786419.2017.1405417

Pejin B, Tešanović K, Jakovljević D, Kaišarević S, Šibul F, Rašeta M, Karaman M. The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity. in Natural Product Research. 2017;:1-5.
doi:10.1080/14786419.2017.1405417 .

Pejin, Boris, Tešanović, K., Jakovljević, Dragica, Kaišarević, S., Šibul, F., Rašeta, M., Karaman, M., "The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity" in Natural Product Research (2017):1-5,
https://doi.org/10.1080/14786419.2017.1405417 . .

TY  - JOUR
AU  - Marin, Marija
AU  - Novaković, Miroslav
AU  - Tešević, Vele
AU  - Kolarević, Stoimir M.
AU  - Vuković-Gačić, Branka
PY  - 2015
UR  - http://www.jbb.uni-plovdiv.bg/
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3970
AB  - The genus Micromeria Benth. (Lamiaceae, Nepetoideae) includes about 130 species, often aromatc. The essential oil and extracts of some Micromeria species have significant antioxidant, antibacterial and antifungal activities. Micromeria thymifolia is endemic species of the Balkan peninsula. It has been traditionally used in the Mediterranean area as condiment and medicinal plant. The aim of this study was to investigate antimicrobial properties of essential oil of wild Micromeria thymifolia against four Gram negative bacteria (Escherichia coli SY252, Pseudomonas aeruginosa ATCC27853, Salmonella enterica ATCC13076 and human patogen Burkholderia cepacia ATCC25416), four Gram positive bacteria (Enterococcus fecalis ATCC29212, Staphylococcus aureus ATCC25923, Bacillus subtilis ATCC6633, Listeria innocua ATCC33090) and two fungi strains (Candida albicans ATCC10231 and Saccharomyces cerevisiae ATCC9763). The MICs of M. thymifolia essential oil against tested bacteria and fungi was assessed using microtitre plate-based antimicrobial assay. MHB was used as growth media for bacteria, with exception of L.innocua when BHI was used, YPD was used for fungi. The results of our investigation showed that the essential oil of wild-growing M. thymifolia possess significant antimicrobial activity against all tested strains except the P. aeruginosa.
PB  - Bulgaria : Plovdiv University Press
T2  - Journal of BioScience and Biotechnology
T1  - Antimicrobial activity of the essential oil of wild-growing Micromeria thymifolia (Scop.) Fritsch
VL  - 4
IS  - 1
SP  - 29
EP  - 31
UR  - https://hdl.handle.net/21.15107/rcub_cer_3970
ER  - 

@article{
author = "Marin, Marija and Novaković, Miroslav and Tešević, Vele and Kolarević, Stoimir M. and Vuković-Gačić, Branka",
year = "2015",
abstract = "The genus Micromeria Benth. (Lamiaceae, Nepetoideae) includes about 130 species, often aromatc. The essential oil and extracts of some Micromeria species have significant antioxidant, antibacterial and antifungal activities. Micromeria thymifolia is endemic species of the Balkan peninsula. It has been traditionally used in the Mediterranean area as condiment and medicinal plant. The aim of this study was to investigate antimicrobial properties of essential oil of wild Micromeria thymifolia against four Gram negative bacteria (Escherichia coli SY252, Pseudomonas aeruginosa ATCC27853, Salmonella enterica ATCC13076 and human patogen Burkholderia cepacia ATCC25416), four Gram positive bacteria (Enterococcus fecalis ATCC29212, Staphylococcus aureus ATCC25923, Bacillus subtilis ATCC6633, Listeria innocua ATCC33090) and two fungi strains (Candida albicans ATCC10231 and Saccharomyces cerevisiae ATCC9763). The MICs of M. thymifolia essential oil against tested bacteria and fungi was assessed using microtitre plate-based antimicrobial assay. MHB was used as growth media for bacteria, with exception of L.innocua when BHI was used, YPD was used for fungi. The results of our investigation showed that the essential oil of wild-growing M. thymifolia possess significant antimicrobial activity against all tested strains except the P. aeruginosa.",
publisher = "Bulgaria : Plovdiv University Press",
journal = "Journal of BioScience and Biotechnology",
title = "Antimicrobial activity of the essential oil of wild-growing Micromeria thymifolia (Scop.) Fritsch",
volume = "4",
number = "1",
pages = "29-31",
url = "https://hdl.handle.net/21.15107/rcub_cer_3970"
}

Marin, M., Novaković, M., Tešević, V., Kolarević, S. M.,& Vuković-Gačić, B.. (2015). Antimicrobial activity of the essential oil of wild-growing Micromeria thymifolia (Scop.) Fritsch. in Journal of BioScience and Biotechnology
Bulgaria : Plovdiv University Press., 4(1), 29-31.
https://hdl.handle.net/21.15107/rcub_cer_3970

Marin M, Novaković M, Tešević V, Kolarević SM, Vuković-Gačić B. Antimicrobial activity of the essential oil of wild-growing Micromeria thymifolia (Scop.) Fritsch. in Journal of BioScience and Biotechnology. 2015;4(1):29-31.
https://hdl.handle.net/21.15107/rcub_cer_3970 .

Marin, Marija, Novaković, Miroslav, Tešević, Vele, Kolarević, Stoimir M., Vuković-Gačić, Branka, "Antimicrobial activity of the essential oil of wild-growing Micromeria thymifolia (Scop.) Fritsch" in Journal of BioScience and Biotechnology, 4, no. 1 (2015):29-31,
https://hdl.handle.net/21.15107/rcub_cer_3970 .

TY  - JOUR
AU  - Marin, Marija
AU  - Novaković, Miroslav
AU  - Tešević, Vele
AU  - Vučković, Ivan
AU  - Milojevic, Natasa
AU  - Vukovic-Gacic, Branka
AU  - Marin, Petar D.
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/965
AB  - The composition of the essential oil of Satureja montana was examined by gas chromatographymass spectrometry and 1H nuclear magnetic resonance spectroscopy. Forty-three compounds were identified, representing approximately 99% of the oil. Major components were ?-terpinene (8.7%), p-cymene (16.9%) and carvacrol (44.5%). The oil was tested for its antioxidant activity by using the 1,1-diphenyl-2-picryl hydrazyl assay and showed dose-dependent free-radical-scavenging activity with an EC50 value of 4.21 mg/ml. The antimicrobial effect of the essential oil was tested against six strains of Gram-negative bacteria, seven strains of Gram-positive bacteria and two fungi. The human pathogens Burkholderia cepacia ATCC 25416 (Gram negative) and Listeria innocua (Gram positive) were used in the investigation of S. montana for the first time. The minimum inhibitory concentration of the essential oil ranged from 0.625 to 5.0 mu l/well for Gram-negative bacteria, and from 0.312 to 1.125 mu l/well for Gram-positive bacteria. For the two fungi tested, Candida and Saccharomyces, the value was 0.234 mu l/tube. The essential oil tested showed significant activity against fungi and Gram-positive bacteria, especially Bacillus subtilis, Staphylococcus epidermidis and Listeria innocua, and among Gram-negative bacteria extreme sensitivity was detected in Escherichia coli SY252, SY252 lpcA and ATTCC 25922 strains. Copyright
PB  - Wiley-Blackwell, Malden
T2  - Flavour and Fragrance Journal
T1  - Antioxidative, antibacterial and antifungal activity of the essential oil of wild-growing Satureja montana L. from Dalmatia, Croatia
VL  - 27
IS  - 3
SP  - 216
EP  - 223
DO  - 10.1002/ffj.3082
ER  - 

@article{
author = "Marin, Marija and Novaković, Miroslav and Tešević, Vele and Vučković, Ivan and Milojevic, Natasa and Vukovic-Gacic, Branka and Marin, Petar D.",
year = "2012",
abstract = "The composition of the essential oil of Satureja montana was examined by gas chromatographymass spectrometry and 1H nuclear magnetic resonance spectroscopy. Forty-three compounds were identified, representing approximately 99% of the oil. Major components were ?-terpinene (8.7%), p-cymene (16.9%) and carvacrol (44.5%). The oil was tested for its antioxidant activity by using the 1,1-diphenyl-2-picryl hydrazyl assay and showed dose-dependent free-radical-scavenging activity with an EC50 value of 4.21 mg/ml. The antimicrobial effect of the essential oil was tested against six strains of Gram-negative bacteria, seven strains of Gram-positive bacteria and two fungi. The human pathogens Burkholderia cepacia ATCC 25416 (Gram negative) and Listeria innocua (Gram positive) were used in the investigation of S. montana for the first time. The minimum inhibitory concentration of the essential oil ranged from 0.625 to 5.0 mu l/well for Gram-negative bacteria, and from 0.312 to 1.125 mu l/well for Gram-positive bacteria. For the two fungi tested, Candida and Saccharomyces, the value was 0.234 mu l/tube. The essential oil tested showed significant activity against fungi and Gram-positive bacteria, especially Bacillus subtilis, Staphylococcus epidermidis and Listeria innocua, and among Gram-negative bacteria extreme sensitivity was detected in Escherichia coli SY252, SY252 lpcA and ATTCC 25922 strains. Copyright",
publisher = "Wiley-Blackwell, Malden",
journal = "Flavour and Fragrance Journal",
title = "Antioxidative, antibacterial and antifungal activity of the essential oil of wild-growing Satureja montana L. from Dalmatia, Croatia",
volume = "27",
number = "3",
pages = "216-223",
doi = "10.1002/ffj.3082"
}

Marin, M., Novaković, M., Tešević, V., Vučković, I., Milojevic, N., Vukovic-Gacic, B.,& Marin, P. D.. (2012). Antioxidative, antibacterial and antifungal activity of the essential oil of wild-growing Satureja montana L. from Dalmatia, Croatia. in Flavour and Fragrance Journal
Wiley-Blackwell, Malden., 27(3), 216-223.
https://doi.org/10.1002/ffj.3082

Marin M, Novaković M, Tešević V, Vučković I, Milojevic N, Vukovic-Gacic B, Marin PD. Antioxidative, antibacterial and antifungal activity of the essential oil of wild-growing Satureja montana L. from Dalmatia, Croatia. in Flavour and Fragrance Journal. 2012;27(3):216-223.
doi:10.1002/ffj.3082 .

Marin, Marija, Novaković, Miroslav, Tešević, Vele, Vučković, Ivan, Milojevic, Natasa, Vukovic-Gacic, Branka, Marin, Petar D., "Antioxidative, antibacterial and antifungal activity of the essential oil of wild-growing Satureja montana L. from Dalmatia, Croatia" in Flavour and Fragrance Journal, 27, no. 3 (2012):216-223,
https://doi.org/10.1002/ffj.3082 . .