TY  - JOUR
AU  - Medić, Ana
AU  - Huttmann, Nico
AU  - Lješević, Marija
AU  - Risha, Yousef
AU  - Berezovski, Maxim
AU  - Minić, Zoran
AU  - Karadžić, Ivanka
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5548
AB  - Polyextremophilic, hydrocarbonoclastic Pseudomonas aeruginosa san ai can survive under extreme environmental challenges in the presence of a variety of pollutants such as organic solvents and hydrocarbons, particularly aromatics, heavy metals, and high pH. To date, the metabolic plasticity of the extremophilic P. aeruginosa, has not been sufficiently studied in regard to the effect of changing carbon sources. Therefore, the present study explores the carbon metabolic pathways of polyextremophilic P. aeruginosa san ai grown on sodium benzoate versus glucose and its potential for aromatic degradation. P. aeruginosa san ai removed/metabolised early 430 mg/L of benzoate for 48 h, demonstrating a high capacity for aromatic degradation. Comparative functional proteomics, targeted metabolomics and genomics analytical approaches were employed to study the carbon metabolism of the P. aeruginosa san ai. Functional proteomic study of selected enzymes participating in the β-ketoadipate and the Entner-Doudoroff pathways revealed a metabolic reconfiguration induced by benzoate compared to glucose. Metabolome analysis implied the existence of both catechol and protocatechuate branches of the β-ketoadipate pathway. Enzymatic study of benzoate grown cultures confirmed the activity of the ortho-catechol branch of the β-ketoadipate pathway. Even high concentrations of benzoate did not show increased stress protein synthesis, testifying to its extremophilic nature capable of surviving in harsh conditions. This ability of Pseudomonas aeruginosa san ai to efficiently degrade benzoate can provide a wide range of use of this strain in environmental and agricultural application.
PB  - Elsevier
T2  - Microbiological Research
T1  - A study of the flexibility of the carbon catabolic pathways of extremophilic  P. aeruginosa san ai exposed to benzoate versus glucose as sole carbon  sources by multi omics analytical platform
VL  - 259
SP  - 126998
DO  - 10.1016/j.micres.2022.126998
ER  - 

@article{
author = "Medić, Ana and Huttmann, Nico and Lješević, Marija and Risha, Yousef and Berezovski, Maxim and Minić, Zoran and Karadžić, Ivanka",
year = "2022",
abstract = "Polyextremophilic, hydrocarbonoclastic Pseudomonas aeruginosa san ai can survive under extreme environmental challenges in the presence of a variety of pollutants such as organic solvents and hydrocarbons, particularly aromatics, heavy metals, and high pH. To date, the metabolic plasticity of the extremophilic P. aeruginosa, has not been sufficiently studied in regard to the effect of changing carbon sources. Therefore, the present study explores the carbon metabolic pathways of polyextremophilic P. aeruginosa san ai grown on sodium benzoate versus glucose and its potential for aromatic degradation. P. aeruginosa san ai removed/metabolised early 430 mg/L of benzoate for 48 h, demonstrating a high capacity for aromatic degradation. Comparative functional proteomics, targeted metabolomics and genomics analytical approaches were employed to study the carbon metabolism of the P. aeruginosa san ai. Functional proteomic study of selected enzymes participating in the β-ketoadipate and the Entner-Doudoroff pathways revealed a metabolic reconfiguration induced by benzoate compared to glucose. Metabolome analysis implied the existence of both catechol and protocatechuate branches of the β-ketoadipate pathway. Enzymatic study of benzoate grown cultures confirmed the activity of the ortho-catechol branch of the β-ketoadipate pathway. Even high concentrations of benzoate did not show increased stress protein synthesis, testifying to its extremophilic nature capable of surviving in harsh conditions. This ability of Pseudomonas aeruginosa san ai to efficiently degrade benzoate can provide a wide range of use of this strain in environmental and agricultural application.",
publisher = "Elsevier",
journal = "Microbiological Research",
title = "A study of the flexibility of the carbon catabolic pathways of extremophilic  P. aeruginosa san ai exposed to benzoate versus glucose as sole carbon  sources by multi omics analytical platform",
volume = "259",
pages = "126998",
doi = "10.1016/j.micres.2022.126998"
}

Medić, A., Huttmann, N., Lješević, M., Risha, Y., Berezovski, M., Minić, Z.,& Karadžić, I.. (2022). A study of the flexibility of the carbon catabolic pathways of extremophilic  P. aeruginosa san ai exposed to benzoate versus glucose as sole carbon  sources by multi omics analytical platform. in Microbiological Research
Elsevier., 259, 126998.
https://doi.org/10.1016/j.micres.2022.126998

Medić A, Huttmann N, Lješević M, Risha Y, Berezovski M, Minić Z, Karadžić I. A study of the flexibility of the carbon catabolic pathways of extremophilic  P. aeruginosa san ai exposed to benzoate versus glucose as sole carbon  sources by multi omics analytical platform. in Microbiological Research. 2022;259:126998.
doi:10.1016/j.micres.2022.126998 .

Medić, Ana, Huttmann, Nico, Lješević, Marija, Risha, Yousef, Berezovski, Maxim, Minić, Zoran, Karadžić, Ivanka, "A study of the flexibility of the carbon catabolic pathways of extremophilic  P. aeruginosa san ai exposed to benzoate versus glucose as sole carbon  sources by multi omics analytical platform" in Microbiological Research, 259 (2022):126998,
https://doi.org/10.1016/j.micres.2022.126998 . .

TY  - JOUR
AU  - Medić, Ana
AU  - Huttmann, Nico
AU  - Lješević, Marija
AU  - Risha, Yousef
AU  - Berezovski, Maxim
AU  - Minić, Zoran
AU  - Karadžić, Ivanka
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5190
AB  - Polyextremophilic, hydrocarbonoclastic Pseudomonas aeruginosa san ai can survive under extreme environmental challenges in the presence of a variety of pollutants such as organic solvents and hydrocarbons, particularly aromatics, heavy metals, and high pH. To date, the metabolic plasticity of the extremophilic P. aeruginosa, has not been sufficiently studied in regard to the effect of changing carbon sources. Therefore, the present study explores the carbon metabolic pathways of polyextremophilic P. aeruginosa san ai grown on sodium benzoate versus glucose and its potential for aromatic degradation. P. aeruginosa san ai removed/metabolised early 430 mg/L of benzoate for 48 h, demonstrating a high capacity for aromatic degradation. Comparative functional proteomics, targeted metabolomics and genomics analytical approaches were employed to study the carbon metabolism of the P. aeruginosa san ai. Functional proteomic study of selected enzymes participating in the β-ketoadipate and the Entner-Doudoroff pathways revealed a metabolic reconfiguration induced by benzoate compared to glucose. Metabolome analysis implied the existence of both catechol and protocatechuate branches of the β-ketoadipate pathway. Enzymatic study of benzoate grown cultures confirmed the activity of the ortho-catechol branch of the β-ketoadipate pathway. Even high concentrations of benzoate did not show increased stress protein synthesis, testifying to its extremophilic nature capable of surviving in harsh conditions. This ability of Pseudomonas aeruginosa san ai to efficiently degrade benzoate can provide a wide range of use of this strain in environmental and agricultural application.
PB  - Elsevier
T2  - Microbiological Research
T1  - A study of the flexibility of the carbon catabolic pathways of extremophilic  P. aeruginosa san ai exposed to benzoate versus glucose as sole carbon  sources by multi omics analytical platform
VL  - 259
SP  - 126998
DO  - 10.1016/j.micres.2022.126998
ER  - 

@article{
author = "Medić, Ana and Huttmann, Nico and Lješević, Marija and Risha, Yousef and Berezovski, Maxim and Minić, Zoran and Karadžić, Ivanka",
year = "2022",
abstract = "Polyextremophilic, hydrocarbonoclastic Pseudomonas aeruginosa san ai can survive under extreme environmental challenges in the presence of a variety of pollutants such as organic solvents and hydrocarbons, particularly aromatics, heavy metals, and high pH. To date, the metabolic plasticity of the extremophilic P. aeruginosa, has not been sufficiently studied in regard to the effect of changing carbon sources. Therefore, the present study explores the carbon metabolic pathways of polyextremophilic P. aeruginosa san ai grown on sodium benzoate versus glucose and its potential for aromatic degradation. P. aeruginosa san ai removed/metabolised early 430 mg/L of benzoate for 48 h, demonstrating a high capacity for aromatic degradation. Comparative functional proteomics, targeted metabolomics and genomics analytical approaches were employed to study the carbon metabolism of the P. aeruginosa san ai. Functional proteomic study of selected enzymes participating in the β-ketoadipate and the Entner-Doudoroff pathways revealed a metabolic reconfiguration induced by benzoate compared to glucose. Metabolome analysis implied the existence of both catechol and protocatechuate branches of the β-ketoadipate pathway. Enzymatic study of benzoate grown cultures confirmed the activity of the ortho-catechol branch of the β-ketoadipate pathway. Even high concentrations of benzoate did not show increased stress protein synthesis, testifying to its extremophilic nature capable of surviving in harsh conditions. This ability of Pseudomonas aeruginosa san ai to efficiently degrade benzoate can provide a wide range of use of this strain in environmental and agricultural application.",
publisher = "Elsevier",
journal = "Microbiological Research",
title = "A study of the flexibility of the carbon catabolic pathways of extremophilic  P. aeruginosa san ai exposed to benzoate versus glucose as sole carbon  sources by multi omics analytical platform",
volume = "259",
pages = "126998",
doi = "10.1016/j.micres.2022.126998"
}

Medić, A., Huttmann, N., Lješević, M., Risha, Y., Berezovski, M., Minić, Z.,& Karadžić, I.. (2022). A study of the flexibility of the carbon catabolic pathways of extremophilic  P. aeruginosa san ai exposed to benzoate versus glucose as sole carbon  sources by multi omics analytical platform. in Microbiological Research
Elsevier., 259, 126998.
https://doi.org/10.1016/j.micres.2022.126998

Medić A, Huttmann N, Lješević M, Risha Y, Berezovski M, Minić Z, Karadžić I. A study of the flexibility of the carbon catabolic pathways of extremophilic  P. aeruginosa san ai exposed to benzoate versus glucose as sole carbon  sources by multi omics analytical platform. in Microbiological Research. 2022;259:126998.
doi:10.1016/j.micres.2022.126998 .

Medić, Ana, Huttmann, Nico, Lješević, Marija, Risha, Yousef, Berezovski, Maxim, Minić, Zoran, Karadžić, Ivanka, "A study of the flexibility of the carbon catabolic pathways of extremophilic  P. aeruginosa san ai exposed to benzoate versus glucose as sole carbon  sources by multi omics analytical platform" in Microbiological Research, 259 (2022):126998,
https://doi.org/10.1016/j.micres.2022.126998 . .

Avdalović, J., Lopičić, Z., Milojković, J., Milić, J., Šoštarić, T., Beškoski, V.,& Miletić, S.. (2021). Nova tehnologija za tretman podzemnih i industrijskih voda kontaminiranih naftnim ugljovodnicima. 
Универзитет у Београду, Институт за хемију технологију и металургију, Институ од националног значаја за Републику Србију..
https://hdl.handle.net/21.15107/rcub_cer_4968

Avdalović J, Lopičić Z, Milojković J, Milić J, Šoštarić T, Beškoski V, Miletić S. Nova tehnologija za tretman podzemnih i industrijskih voda kontaminiranih naftnim ugljovodnicima. 2021;.
https://hdl.handle.net/21.15107/rcub_cer_4968 .

Avdalović, Jelena, Lopičić, Zorica, Milojković, Jelena, Milić, Jelena, Šoštarić, Tatjana, Beškoski, Vladimir, Miletić, Srđan, "Nova tehnologija za tretman podzemnih i industrijskih voda kontaminiranih naftnim ugljovodnicima" (2021),
https://hdl.handle.net/21.15107/rcub_cer_4968 .

TY  - CONF
AU  - Šolević Knudsen, Tatjana
AU  - Ilić, Mila
AU  - Miletić, Srđan
AU  - Bulatović, Sandra
AU  - Vrvić, Miroslav
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4948
AB  - The aim of this research was characterization of oil pollutants in the soil and sediments
in the vicinity of one of the largest district heating plants in Belgrade (Capital of Serbia).
The soil and sediment samples (109 in total) were collected in spring 2015. From these
samples, the extractable organic matter was isolated using a Soxhlet apparatus, and
fractionated into fractions of: saturated hydrocarbons, aromatic hydrocarbons, and polar
compounds. Saturated hydrocarbons were analysed by gas chromatography – mass
spectrometry.
Saturated biomarkers revealed that the surface samples contained mixtures of a diesel
fuel and native organic substance while the pollutant in the subsurface samples was a mixture
of a diesel fuel and a heavy oil fuel. Sterane and terpane biomarkers confirmed presence of
different oil pollutants at this location.
It was concluded that the oil pollutants saturated hydrocarbons at this location
originate from multiple discharges of diesel and/or a heavy oil fuel.
PB  - Croatia : Association for Promotion of Holistic Approach to Environment
C3  - Proceedings book - 2nd International conference „The Holistic Approach to Environment“ May 28th, 2021, Virtual conference
T1  - Characterization of oil pollutants in soil and sediments in the vicinity of a heating plant – alluvial sediments of the Sava river, Belgrade, Serbia
SP  - 612
EP  - 621
UR  - https://hdl.handle.net/21.15107/rcub_cer_4948
ER  - 

@conference{
author = "Šolević Knudsen, Tatjana and Ilić, Mila and Miletić, Srđan and Bulatović, Sandra and Vrvić, Miroslav",
year = "2021",
abstract = "The aim of this research was characterization of oil pollutants in the soil and sediments
in the vicinity of one of the largest district heating plants in Belgrade (Capital of Serbia).
The soil and sediment samples (109 in total) were collected in spring 2015. From these
samples, the extractable organic matter was isolated using a Soxhlet apparatus, and
fractionated into fractions of: saturated hydrocarbons, aromatic hydrocarbons, and polar
compounds. Saturated hydrocarbons were analysed by gas chromatography – mass
spectrometry.
Saturated biomarkers revealed that the surface samples contained mixtures of a diesel
fuel and native organic substance while the pollutant in the subsurface samples was a mixture
of a diesel fuel and a heavy oil fuel. Sterane and terpane biomarkers confirmed presence of
different oil pollutants at this location.
It was concluded that the oil pollutants saturated hydrocarbons at this location
originate from multiple discharges of diesel and/or a heavy oil fuel.",
publisher = "Croatia : Association for Promotion of Holistic Approach to Environment",
journal = "Proceedings book - 2nd International conference „The Holistic Approach to Environment“ May 28th, 2021, Virtual conference",
title = "Characterization of oil pollutants in soil and sediments in the vicinity of a heating plant – alluvial sediments of the Sava river, Belgrade, Serbia",
pages = "612-621",
url = "https://hdl.handle.net/21.15107/rcub_cer_4948"
}

Šolević Knudsen, T., Ilić, M., Miletić, S., Bulatović, S.,& Vrvić, M.. (2021). Characterization of oil pollutants in soil and sediments in the vicinity of a heating plant – alluvial sediments of the Sava river, Belgrade, Serbia. in Proceedings book - 2nd International conference „The Holistic Approach to Environment“ May 28th, 2021, Virtual conference
Croatia : Association for Promotion of Holistic Approach to Environment., 612-621.
https://hdl.handle.net/21.15107/rcub_cer_4948

Šolević Knudsen T, Ilić M, Miletić S, Bulatović S, Vrvić M. Characterization of oil pollutants in soil and sediments in the vicinity of a heating plant – alluvial sediments of the Sava river, Belgrade, Serbia. in Proceedings book - 2nd International conference „The Holistic Approach to Environment“ May 28th, 2021, Virtual conference. 2021;:612-621.
https://hdl.handle.net/21.15107/rcub_cer_4948 .

Šolević Knudsen, Tatjana, Ilić, Mila, Miletić, Srđan, Bulatović, Sandra, Vrvić, Miroslav, "Characterization of oil pollutants in soil and sediments in the vicinity of a heating plant – alluvial sediments of the Sava river, Belgrade, Serbia" in Proceedings book - 2nd International conference „The Holistic Approach to Environment“ May 28th, 2021, Virtual conference (2021):612-621,
https://hdl.handle.net/21.15107/rcub_cer_4948 .

TY  - CONF
AU  - Dević, Gordana
AU  - Ilić, Mila
AU  - Bulatović, Sandra
AU  - Miletić, Srđan
AU  - Vrvić, Miroslav
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4960
AB  - Environmental pollution with petroleum and petrochemical products has attracted much attention in recent years. The present study is focused on the investigation of urban soil pollution in the area of thermal plant New Belgrade with more than 200000 residents.
PB  - Serbian Chemical Society
C3  - Book of abstracts - 21st European Meeting on Environmental Chemistry (EMEC21)
T1  - Soil Contamination by Petroleum Products in the Urban Environments: Belgrade, Serbia
SP  - 156
UR  - https://hdl.handle.net/21.15107/rcub_cer_4960
ER  - 

@conference{
author = "Dević, Gordana and Ilić, Mila and Bulatović, Sandra and Miletić, Srđan and Vrvić, Miroslav",
year = "2021",
abstract = "Environmental pollution with petroleum and petrochemical products has attracted much attention in recent years. The present study is focused on the investigation of urban soil pollution in the area of thermal plant New Belgrade with more than 200000 residents.",
publisher = "Serbian Chemical Society",
journal = "Book of abstracts - 21st European Meeting on Environmental Chemistry (EMEC21)",
title = "Soil Contamination by Petroleum Products in the Urban Environments: Belgrade, Serbia",
pages = "156",
url = "https://hdl.handle.net/21.15107/rcub_cer_4960"
}

Dević, G., Ilić, M., Bulatović, S., Miletić, S.,& Vrvić, M.. (2021). Soil Contamination by Petroleum Products in the Urban Environments: Belgrade, Serbia. in Book of abstracts - 21st European Meeting on Environmental Chemistry (EMEC21)
Serbian Chemical Society., 156.
https://hdl.handle.net/21.15107/rcub_cer_4960

Dević G, Ilić M, Bulatović S, Miletić S, Vrvić M. Soil Contamination by Petroleum Products in the Urban Environments: Belgrade, Serbia. in Book of abstracts - 21st European Meeting on Environmental Chemistry (EMEC21). 2021;:156.
https://hdl.handle.net/21.15107/rcub_cer_4960 .

Dević, Gordana, Ilić, Mila, Bulatović, Sandra, Miletić, Srđan, Vrvić, Miroslav, "Soil Contamination by Petroleum Products in the Urban Environments: Belgrade, Serbia" in Book of abstracts - 21st European Meeting on Environmental Chemistry (EMEC21) (2021):156,
https://hdl.handle.net/21.15107/rcub_cer_4960 .

TY  - CONF
AU  - Medić, A.
AU  - Lješević, Marija
AU  - Karadžić, Ivanka
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5126
AB  - Poster presented at 21st European Meeting on Environmental Chemistry (EMEC21), 30 November-3 december 2021, Novi Sad, Serbia
T1  - Metabolomic study of the biodegradation pathway of sodium-benzoate in pseudomonas aeruginosa san ai
UR  - https://hdl.handle.net/21.15107/rcub_cer_5126
ER  - 

@conference{
author = "Medić, A. and Lješević, Marija and Karadžić, Ivanka",
year = "2021",
abstract = "Poster presented at 21st European Meeting on Environmental Chemistry (EMEC21), 30 November-3 december 2021, Novi Sad, Serbia",
title = "Metabolomic study of the biodegradation pathway of sodium-benzoate in pseudomonas aeruginosa san ai",
url = "https://hdl.handle.net/21.15107/rcub_cer_5126"
}

Medić, A., Lješević, M.,& Karadžić, I.. (2021). Metabolomic study of the biodegradation pathway of sodium-benzoate in pseudomonas aeruginosa san ai. .
https://hdl.handle.net/21.15107/rcub_cer_5126

Medić A, Lješević M, Karadžić I. Metabolomic study of the biodegradation pathway of sodium-benzoate in pseudomonas aeruginosa san ai. 2021;.
https://hdl.handle.net/21.15107/rcub_cer_5126 .

Medić, A., Lješević, Marija, Karadžić, Ivanka, "Metabolomic study of the biodegradation pathway of sodium-benzoate in pseudomonas aeruginosa san ai" (2021),
https://hdl.handle.net/21.15107/rcub_cer_5126 .

TY  - CONF
AU  - Medić, A.
AU  - Lješević, Marija
AU  - Karadžić, Ivanka
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5125
AB  - The goal of this study was to analyze the products of benzoate degradation by polyextremophilic, hydrocarbonoclastic Pseudomonas aeruginosa san ai using targeted metabolomic analysis in order to determine the specificity of the metabolic pathway of sodium-benzoate.
PB  - Belgrade : Serbian Chemical Society
C3  - 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia
T1  - Metabolomic study of the biodegradation pathway of sodium-benzoate in pseudomonas aeruginosa san ai
SP  - 160
UR  - https://hdl.handle.net/21.15107/rcub_cer_5125
ER  - 

@conference{
author = "Medić, A. and Lješević, Marija and Karadžić, Ivanka",
year = "2021",
abstract = "The goal of this study was to analyze the products of benzoate degradation by polyextremophilic, hydrocarbonoclastic Pseudomonas aeruginosa san ai using targeted metabolomic analysis in order to determine the specificity of the metabolic pathway of sodium-benzoate.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia",
title = "Metabolomic study of the biodegradation pathway of sodium-benzoate in pseudomonas aeruginosa san ai",
pages = "160",
url = "https://hdl.handle.net/21.15107/rcub_cer_5125"
}

Medić, A., Lješević, M.,& Karadžić, I.. (2021). Metabolomic study of the biodegradation pathway of sodium-benzoate in pseudomonas aeruginosa san ai. in 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia
Belgrade : Serbian Chemical Society., 160.
https://hdl.handle.net/21.15107/rcub_cer_5125

Medić A, Lješević M, Karadžić I. Metabolomic study of the biodegradation pathway of sodium-benzoate in pseudomonas aeruginosa san ai. in 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia. 2021;:160.
https://hdl.handle.net/21.15107/rcub_cer_5125 .

Medić, A., Lješević, Marija, Karadžić, Ivanka, "Metabolomic study of the biodegradation pathway of sodium-benzoate in pseudomonas aeruginosa san ai" in 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia (2021):160,
https://hdl.handle.net/21.15107/rcub_cer_5125 .

TY  - CHAP
AU  - Lugonja, Nikoleta
AU  - Spasić, Snežana
PY  - 2020
UR  - https://novapublishers.com/shop/new-research-on-breastfeeding-and-breast-milk/
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3968
AB  - Breast milk is considered to be the only and the best nutrition for newborn infants until six months of age. However, some of the most important problems regarding the nutrition of infants after preterm delivery are due to the fact that preterm milk is produced before complete maturation of mammary glands and that the preterm infant’s gastrointestinal tract is not mature enough at the time of partition. Since human milk has unique properties in promoting gastrointestinal maturation and immunological benefits, it is very important to implement strategies of fortification to appropriately actuate its benefits. Donor breast milk from milk banks is widely used when mother’s own milk is not available or when it is in short supply for preterm infants. While donor breast milk retains some of the biological properties and clinical benefits of mother’s own milk, it requires additional care in terms of fortification, especially if the donor milk is from a pool of term breast milk which is somewhat different than preterm breast milk. As nutritional strategies improve, the ultimate goal is to minimize extrauterine growth restriction and promote appropriate growth and development of premature infants. Another problem with breast milk, which is quite often overlooked, is that after six months, there is not enough of essential microelements (Zn, Fe and Cu) to satisfy baby’s needs, and therefore, the milk must be effectively supplemented. In this chapter we review the following aspects of breast milk for preterm infants: 1) The main nutritive factors of breast milk; 2) The use of fortifier as breast milk supplement; 3) Significance of microelements in preterm nutrition; and 4) Health outcomes of breast milk for preterm infants.
PB  - Nova Science Publishers, Inc.
T2  - New Research on Breastfeeding and Breast Milk
T1  - Breast Milk for Premature Infants: Nutritive and health Aspects
SP  - 27
EP  - 68
UR  - https://hdl.handle.net/21.15107/rcub_cer_3968
ER  - 

@inbook{
author = "Lugonja, Nikoleta and Spasić, Snežana",
year = "2020",
abstract = "Breast milk is considered to be the only and the best nutrition for newborn infants until six months of age. However, some of the most important problems regarding the nutrition of infants after preterm delivery are due to the fact that preterm milk is produced before complete maturation of mammary glands and that the preterm infant’s gastrointestinal tract is not mature enough at the time of partition. Since human milk has unique properties in promoting gastrointestinal maturation and immunological benefits, it is very important to implement strategies of fortification to appropriately actuate its benefits. Donor breast milk from milk banks is widely used when mother’s own milk is not available or when it is in short supply for preterm infants. While donor breast milk retains some of the biological properties and clinical benefits of mother’s own milk, it requires additional care in terms of fortification, especially if the donor milk is from a pool of term breast milk which is somewhat different than preterm breast milk. As nutritional strategies improve, the ultimate goal is to minimize extrauterine growth restriction and promote appropriate growth and development of premature infants. Another problem with breast milk, which is quite often overlooked, is that after six months, there is not enough of essential microelements (Zn, Fe and Cu) to satisfy baby’s needs, and therefore, the milk must be effectively supplemented. In this chapter we review the following aspects of breast milk for preterm infants: 1) The main nutritive factors of breast milk; 2) The use of fortifier as breast milk supplement; 3) Significance of microelements in preterm nutrition; and 4) Health outcomes of breast milk for preterm infants.",
publisher = "Nova Science Publishers, Inc.",
journal = "New Research on Breastfeeding and Breast Milk",
booktitle = "Breast Milk for Premature Infants: Nutritive and health Aspects",
pages = "27-68",
url = "https://hdl.handle.net/21.15107/rcub_cer_3968"
}

Lugonja, N.,& Spasić, S.. (2020). Breast Milk for Premature Infants: Nutritive and health Aspects. in New Research on Breastfeeding and Breast Milk
Nova Science Publishers, Inc.., 27-68.
https://hdl.handle.net/21.15107/rcub_cer_3968

Lugonja N, Spasić S. Breast Milk for Premature Infants: Nutritive and health Aspects. in New Research on Breastfeeding and Breast Milk. 2020;:27-68.
https://hdl.handle.net/21.15107/rcub_cer_3968 .

Lugonja, Nikoleta, Spasić, Snežana, "Breast Milk for Premature Infants: Nutritive and health Aspects" in New Research on Breastfeeding and Breast Milk (2020):27-68,
https://hdl.handle.net/21.15107/rcub_cer_3968 .

TY  - JOUR
AU  - Bulatović, Sandra
AU  - Marić, Nenad
AU  - Šolević Knudsen, Tatjana
AU  - Avdalović, Jelena
AU  - Ilić, Mila
AU  - Jovančićević, Branimir
AU  - Vrvić, Miroslav
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3731
UR  - https://www.shd-pub.org.rs/index.php/JSCS/article/view/8725
AB  - Due to their extensive use, petroleum hydrocarbons are among the most common groundwater contaminants. Compared to the traditional methods of physical pumping of contamination from the aquifer and subsequent treatment (i.e., pump and treat), bioremediation is an economically cost-effective
technology. The aim of this remediation approach is to transform biologically contaminants, most often by microbiological activity, into non-toxic compounds.
More precisely, it is an active remediation process that involves biostimulation (increase of aquifer oxygenation, addition of nutrients) and/or bioaugmentation (injection of a concentrated and specialized population of microorganisms).
Using both biostimulation and bioaugmentation, enhanced in situ groundwater bioremediation was applied at a hydrocarbon-contaminated site in
Belgrade. The bioremediation treatment, applied over twelve months, was highly efficient in reducing the concentrations of total petroleum hydrocarbon
(TPH) to acceptable levels. The concentration of TPH in the piezometer P-5 was reduced by 98.55 %, in the piezometer P-6 by 98.30 % and in the piezometer
P-7 by 98.09 %. These results provided strong evidence on the potential of this remediation approach to overcome site-limiting factors and enhance
microbiological activity in order to reduce groundwater contamination.
AB  - Услед широке употребе, нафтни угљоводоници спадају међу најчешће загађујуће супстанце у подземним водама. У поређењу са конвенционалним методама физичког црпења загађења из издани (“пумпај и третирај”), биоремедијација је економски исплатива технологија. Циљ овог ремедијационог поступка је да се биолошки, најчешће микробиолошком активношћу, трансформишу загађујуће супстанце до нетоксичних једињења. Прецизније, ово је активан ремедијациони процес који ускључује биостимулацију (повећање оксичности средине, додавање нутријената) и/или биоаугментацију (додавање концентроване и специјализоване популације микроорганизама). Користећи биостимулацију и биоаугментацију, стимулисана ин ситу биоремедијација подземних вода примењена је на локацији загађеној угљоводоницима у Београду. Биоремедија циони третман, примењиван током периода од дванаест месеци, био је веома ефикасан у смањењу концентрација укупних нафтних угљоводоника до прихватљивих вредности.У пиезометру P-5 концентрација TPH смањена је за 98,55 %, у пиезометру P-6 за 98,30%, а у пиезометру P-7 концентрација TPH смањена је за 98,09 %. Добијени резултатипотврђују потенцијал примењеног ремедијационог поступка у превазилажењу ограничавајућих услова средине и стимулисању микробиолошке активности у циљу смањења загађења подземних вода.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Bioremediation of groundwater contaminated with petroleum hydrocarbons applied at a site in Belgrade (Serbia)
T1  - Bioremedijacija podzemnih voda zagađenih naftnim ugljovodonicima primenjena u blizini termo-energetskog postrojenja u Beogradu
VL  - 85
IS  - 8
SP  - 1067
EP  - 1081
DO  - 10.2298/JSC191023003B
ER  - 

@article{
author = "Bulatović, Sandra and Marić, Nenad and Šolević Knudsen, Tatjana and Avdalović, Jelena and Ilić, Mila and Jovančićević, Branimir and Vrvić, Miroslav",
year = "2020",
abstract = "Due to their extensive use, petroleum hydrocarbons are among the most common groundwater contaminants. Compared to the traditional methods of physical pumping of contamination from the aquifer and subsequent treatment (i.e., pump and treat), bioremediation is an economically cost-effective
technology. The aim of this remediation approach is to transform biologically contaminants, most often by microbiological activity, into non-toxic compounds.
More precisely, it is an active remediation process that involves biostimulation (increase of aquifer oxygenation, addition of nutrients) and/or bioaugmentation (injection of a concentrated and specialized population of microorganisms).
Using both biostimulation and bioaugmentation, enhanced in situ groundwater bioremediation was applied at a hydrocarbon-contaminated site in
Belgrade. The bioremediation treatment, applied over twelve months, was highly efficient in reducing the concentrations of total petroleum hydrocarbon
(TPH) to acceptable levels. The concentration of TPH in the piezometer P-5 was reduced by 98.55 %, in the piezometer P-6 by 98.30 % and in the piezometer
P-7 by 98.09 %. These results provided strong evidence on the potential of this remediation approach to overcome site-limiting factors and enhance
microbiological activity in order to reduce groundwater contamination., Услед широке употребе, нафтни угљоводоници спадају међу најчешће загађујуће супстанце у подземним водама. У поређењу са конвенционалним методама физичког црпења загађења из издани (“пумпај и третирај”), биоремедијација је економски исплатива технологија. Циљ овог ремедијационог поступка је да се биолошки, најчешће микробиолошком активношћу, трансформишу загађујуће супстанце до нетоксичних једињења. Прецизније, ово је активан ремедијациони процес који ускључује биостимулацију (повећање оксичности средине, додавање нутријената) и/или биоаугментацију (додавање концентроване и специјализоване популације микроорганизама). Користећи биостимулацију и биоаугментацију, стимулисана ин ситу биоремедијација подземних вода примењена је на локацији загађеној угљоводоницима у Београду. Биоремедија циони третман, примењиван током периода од дванаест месеци, био је веома ефикасан у смањењу концентрација укупних нафтних угљоводоника до прихватљивих вредности.У пиезометру P-5 концентрација TPH смањена је за 98,55 %, у пиезометру P-6 за 98,30%, а у пиезометру P-7 концентрација TPH смањена је за 98,09 %. Добијени резултатипотврђују потенцијал примењеног ремедијационог поступка у превазилажењу ограничавајућих услова средине и стимулисању микробиолошке активности у циљу смањења загађења подземних вода.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Bioremediation of groundwater contaminated with petroleum hydrocarbons applied at a site in Belgrade (Serbia), Bioremedijacija podzemnih voda zagađenih naftnim ugljovodonicima primenjena u blizini termo-energetskog postrojenja u Beogradu",
volume = "85",
number = "8",
pages = "1067-1081",
doi = "10.2298/JSC191023003B"
}

Bulatović, S., Marić, N., Šolević Knudsen, T., Avdalović, J., Ilić, M., Jovančićević, B.,& Vrvić, M.. (2020). Bioremediation of groundwater contaminated with petroleum hydrocarbons applied at a site in Belgrade (Serbia). in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 85(8), 1067-1081.
https://doi.org/10.2298/JSC191023003B

Bulatović S, Marić N, Šolević Knudsen T, Avdalović J, Ilić M, Jovančićević B, Vrvić M. Bioremediation of groundwater contaminated with petroleum hydrocarbons applied at a site in Belgrade (Serbia). in Journal of the Serbian Chemical Society. 2020;85(8):1067-1081.
doi:10.2298/JSC191023003B .

Bulatović, Sandra, Marić, Nenad, Šolević Knudsen, Tatjana, Avdalović, Jelena, Ilić, Mila, Jovančićević, Branimir, Vrvić, Miroslav, "Bioremediation of groundwater contaminated with petroleum hydrocarbons applied at a site in Belgrade (Serbia)" in Journal of the Serbian Chemical Society, 85, no. 8 (2020):1067-1081,
https://doi.org/10.2298/JSC191023003B . .

TY  - JOUR
AU  - Dević, Gordana
AU  - Ilić, Mila
AU  - Zildžović, Snežana
AU  - Avdalović, Jelena
AU  - Miletić, Srđan
AU  - Bulatović, Sandra
AU  - Vrvić, Miroslav
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3949
AB  - Concentrations of 10 potentially toxic trace elements were measured in soil samples collected from 18 sites in urban areas of Belgrade, the capital and the largest city in Serbia. Samples were analysed in order to assess the extent of soil contamination and to distinguish natural and anthropogenic input. The results demonstrated a general Zn, Pb, and Cd enrichment in surface samples, hence, after comparison with guidelines, it has been determined that there is a potential risk for human health. In the surface and buried samples, traces of cooper were detected. The highest concentrations of Cr (121 ± 12.3 mg/kg) and Ni (94.9 ± 12.6 mg/kg) were found at a sediment depth of 2 m and should be ascribed to geogenic sources. The results of HCA and PCA analysis supported a natural origin of Co, Cu, Mn, Cr, and Ni, while Cd, Zn, and Pb originated from anthropogenic inputs. Based on the pollution indices, Cd made the most dominant contribution, posing a high contamination risk in the studied area. Results of Nemerow pollution index (PIN) and potential ecological risk index (PER) demonstrated that pollution by heavy metals in sediments on several sites is moderately intense.
PB  - Taylor & Francis Group LLC
T2  - Journal of Environmental Science and Health, Part A
T1  - Investigation of potentially toxic elements in urban sediments in Belgrade, Serbia
VL  - 55
IS  - 6
SP  - 765
EP  - 775
DO  - 10.1080/10934529.2020.1741999
ER  - 

@article{
author = "Dević, Gordana and Ilić, Mila and Zildžović, Snežana and Avdalović, Jelena and Miletić, Srđan and Bulatović, Sandra and Vrvić, Miroslav",
year = "2020",
abstract = "Concentrations of 10 potentially toxic trace elements were measured in soil samples collected from 18 sites in urban areas of Belgrade, the capital and the largest city in Serbia. Samples were analysed in order to assess the extent of soil contamination and to distinguish natural and anthropogenic input. The results demonstrated a general Zn, Pb, and Cd enrichment in surface samples, hence, after comparison with guidelines, it has been determined that there is a potential risk for human health. In the surface and buried samples, traces of cooper were detected. The highest concentrations of Cr (121 ± 12.3 mg/kg) and Ni (94.9 ± 12.6 mg/kg) were found at a sediment depth of 2 m and should be ascribed to geogenic sources. The results of HCA and PCA analysis supported a natural origin of Co, Cu, Mn, Cr, and Ni, while Cd, Zn, and Pb originated from anthropogenic inputs. Based on the pollution indices, Cd made the most dominant contribution, posing a high contamination risk in the studied area. Results of Nemerow pollution index (PIN) and potential ecological risk index (PER) demonstrated that pollution by heavy metals in sediments on several sites is moderately intense.",
publisher = "Taylor & Francis Group LLC",
journal = "Journal of Environmental Science and Health, Part A",
title = "Investigation of potentially toxic elements in urban sediments in Belgrade, Serbia",
volume = "55",
number = "6",
pages = "765-775",
doi = "10.1080/10934529.2020.1741999"
}

Dević, G., Ilić, M., Zildžović, S., Avdalović, J., Miletić, S., Bulatović, S.,& Vrvić, M.. (2020). Investigation of potentially toxic elements in urban sediments in Belgrade, Serbia. in Journal of Environmental Science and Health, Part A
Taylor & Francis Group LLC., 55(6), 765-775.
https://doi.org/10.1080/10934529.2020.1741999

Dević G, Ilić M, Zildžović S, Avdalović J, Miletić S, Bulatović S, Vrvić M. Investigation of potentially toxic elements in urban sediments in Belgrade, Serbia. in Journal of Environmental Science and Health, Part A. 2020;55(6):765-775.
doi:10.1080/10934529.2020.1741999 .

Dević, Gordana, Ilić, Mila, Zildžović, Snežana, Avdalović, Jelena, Miletić, Srđan, Bulatović, Sandra, Vrvić, Miroslav, "Investigation of potentially toxic elements in urban sediments in Belgrade, Serbia" in Journal of Environmental Science and Health, Part A, 55, no. 6 (2020):765-775,
https://doi.org/10.1080/10934529.2020.1741999 . .

TY  - DATA
AU  - Bulatović, Sandra
AU  - Marić, Nenad
AU  - Šolević Knudsen, Tatjana
AU  - Avdalović, Jelena
AU  - Ilić, Mila
AU  - Jovančićević, Branimir
AU  - Vrvić, Miroslav
PY  - 2020
UR  - https://www.shd-pub.org.rs/index.php/JSCS/article/view/8725
UR  - https://www.shd-pub.org.rs/index.php/JSCS/article/view/8725/1176
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4520
AB  - Geoelogical settings; Fig. 1-S. The geographical position of the thermo-energetic plant in Belgrade and spatial distribution of 10 piezometers; Fig. 2-S. A simplified geological cross-section along the investigated area;
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Supplementary material to: "Bioremediation of groundwater contaminated with petroleum hydrocarbons applied at a site in Belgrade (Serbia)"
UR  - https://hdl.handle.net/21.15107/rcub_cer_4520
ER  - 

@misc{
author = "Bulatović, Sandra and Marić, Nenad and Šolević Knudsen, Tatjana and Avdalović, Jelena and Ilić, Mila and Jovančićević, Branimir and Vrvić, Miroslav",
year = "2020",
abstract = "Geoelogical settings; Fig. 1-S. The geographical position of the thermo-energetic plant in Belgrade and spatial distribution of 10 piezometers; Fig. 2-S. A simplified geological cross-section along the investigated area;",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Supplementary material to: "Bioremediation of groundwater contaminated with petroleum hydrocarbons applied at a site in Belgrade (Serbia)"",
url = "https://hdl.handle.net/21.15107/rcub_cer_4520"
}

Bulatović, S., Marić, N., Šolević Knudsen, T., Avdalović, J., Ilić, M., Jovančićević, B.,& Vrvić, M.. (2020). Supplementary material to: "Bioremediation of groundwater contaminated with petroleum hydrocarbons applied at a site in Belgrade (Serbia)". in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society..
https://hdl.handle.net/21.15107/rcub_cer_4520

Bulatović S, Marić N, Šolević Knudsen T, Avdalović J, Ilić M, Jovančićević B, Vrvić M. Supplementary material to: "Bioremediation of groundwater contaminated with petroleum hydrocarbons applied at a site in Belgrade (Serbia)". in Journal of the Serbian Chemical Society. 2020;.
https://hdl.handle.net/21.15107/rcub_cer_4520 .

Bulatović, Sandra, Marić, Nenad, Šolević Knudsen, Tatjana, Avdalović, Jelena, Ilić, Mila, Jovančićević, Branimir, Vrvić, Miroslav, "Supplementary material to: "Bioremediation of groundwater contaminated with petroleum hydrocarbons applied at a site in Belgrade (Serbia)"" in Journal of the Serbian Chemical Society (2020),
https://hdl.handle.net/21.15107/rcub_cer_4520 .

TY  - JOUR
AU  - Lješević, Marija
AU  - Milić, Jelena
AU  - Gojgić-Cvijović, Gordana
AU  - Šolević Knudsen, Tatjana
AU  - Ilić, Mila
AU  - Avdalović, Jelena
AU  - Vrvić, Miroslav
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3517
AB  - Within a 30-day incubation laboratory study, the polycyclic aromatic hydrocarbon (PAH) degradation profile of two bacteria, Planomicrobium sp. RNP01 and Rhodococcus sp. RNP05 were studied by three microtiter plate assays to reveal the combination of certain biological and biochemical characteristics which are reliable indicators in evaluation of bacterial biodegradation abilities. The three assays, which are hydrocarbon growth assay, 2,6-DCPIP assay and dehydrogenase activity assay revealed that Rhodococcus sp. RNP05 exhibited better potential for PAH degradation than Planomicrobium sp. RNP01. Differences between initial and final optical density and specific growth rate constants were significantly higher (r = 0.995, P < 0.05) in case of Rhodococcus sp. RNP05 on all tested substrates, as compared to Planomicrobium sp. RNP01. This was confirmed by GC-FID analyses. Dehydrogenase activity of Rhodococcus sp. RNP05 was higher (r = 0.9995, P < 0.05) than Planomicrobium sp. RNP01 and correlated positively with the hydrocarbon growth assay (r = 0.999, P < 0.05, for Rhodococcus sp. RNP05, r = 0.986, P < 0.05 for Planomicrobium sp. RNP01). This study has shown that the combination of these assays could be used for determining the bioremediation potential of PAHs in petroleum contaminated soil with the ability of screening a large number of bacterial strains.
AB  - Degradacija policikličnih aromatičnih ugljovodonika (polycyclic aromatic hydrocarbons - PAH) ispitivana je testovima u mikrotitar pločama pomoću dva bakterijska soja Planomicrobium sp. RNP01 i Rhodococcus sp. RNP05, u periodu od 30 dana. Rezultati ispitivanja su ukazali da se kombinacijom određenih bioloških i biohemijskih karakteristika mogu kreirati dobri indikatori u proceni bakterijskog degradacionog potencijala. Tri testa, 2,6-DCPIP test, test dehidrogenazne aktivnosti i test rasta na ugljovodonicima pokazali su da Rhodococcus sp. RNP05 ima veći potencijal za degradaciju PAH jednjenja u odnosu na Planomicrobium sp. RNP01. Razlike u početnoj i krajnjoj optičkoj gustini i specifične konstante rasta bile su značajno više (r = 0,995, P < 0,05) u testu sa Rhodococcus sp. RNP05 na svim testiranim supstratima, u poređenju sa Planomicrobium sp. RNP01, a dobijeni rezultati su potvrđeni gasno-hromatogafskom-FID analizom. Dehidrogenazna aktivnost soja Rhodococcus sp. RNP05 bila je viša u odnosu na Planomicrobium sp. RNP01 (r = 0,9995, P < 0,05) i u pozitivnoj korelaciji sa testom rasta na ugljovodonicima (r = 0,999, P < 0,05, za Rhodococcus sp. RNP05, r = 0,986, P < 0,05 za Planomicrobium sp. RNP01). Rezultati prikazanog istraživanja ukazuju na to da se kombinacija ovih testova može koristiti za određivanje bioremedijacionog potencijala za razgradnju PAH jedinjenja u zemljištu zagađenim naftom, pri čemu se dobija i mogućnost testiranja velikog broja bakterijskih sojeva.
PB  - Savez hemijskih inženjera Srbije, Beograd
T2  - Chemical Industry and Chemical Engineering Quarterly
T1  - Evaluation of assays for screening polycyclic aromatic hydrocarbon-degrading potential of bacteria
VL  - 26
IS  - 1
SP  - 41
EP  - 48
DO  - 10.2298/CICEQ190220023L
ER  - 

@article{
author = "Lješević, Marija and Milić, Jelena and Gojgić-Cvijović, Gordana and Šolević Knudsen, Tatjana and Ilić, Mila and Avdalović, Jelena and Vrvić, Miroslav",
year = "2020",
abstract = "Within a 30-day incubation laboratory study, the polycyclic aromatic hydrocarbon (PAH) degradation profile of two bacteria, Planomicrobium sp. RNP01 and Rhodococcus sp. RNP05 were studied by three microtiter plate assays to reveal the combination of certain biological and biochemical characteristics which are reliable indicators in evaluation of bacterial biodegradation abilities. The three assays, which are hydrocarbon growth assay, 2,6-DCPIP assay and dehydrogenase activity assay revealed that Rhodococcus sp. RNP05 exhibited better potential for PAH degradation than Planomicrobium sp. RNP01. Differences between initial and final optical density and specific growth rate constants were significantly higher (r = 0.995, P < 0.05) in case of Rhodococcus sp. RNP05 on all tested substrates, as compared to Planomicrobium sp. RNP01. This was confirmed by GC-FID analyses. Dehydrogenase activity of Rhodococcus sp. RNP05 was higher (r = 0.9995, P < 0.05) than Planomicrobium sp. RNP01 and correlated positively with the hydrocarbon growth assay (r = 0.999, P < 0.05, for Rhodococcus sp. RNP05, r = 0.986, P < 0.05 for Planomicrobium sp. RNP01). This study has shown that the combination of these assays could be used for determining the bioremediation potential of PAHs in petroleum contaminated soil with the ability of screening a large number of bacterial strains., Degradacija policikličnih aromatičnih ugljovodonika (polycyclic aromatic hydrocarbons - PAH) ispitivana je testovima u mikrotitar pločama pomoću dva bakterijska soja Planomicrobium sp. RNP01 i Rhodococcus sp. RNP05, u periodu od 30 dana. Rezultati ispitivanja su ukazali da se kombinacijom određenih bioloških i biohemijskih karakteristika mogu kreirati dobri indikatori u proceni bakterijskog degradacionog potencijala. Tri testa, 2,6-DCPIP test, test dehidrogenazne aktivnosti i test rasta na ugljovodonicima pokazali su da Rhodococcus sp. RNP05 ima veći potencijal za degradaciju PAH jednjenja u odnosu na Planomicrobium sp. RNP01. Razlike u početnoj i krajnjoj optičkoj gustini i specifične konstante rasta bile su značajno više (r = 0,995, P < 0,05) u testu sa Rhodococcus sp. RNP05 na svim testiranim supstratima, u poređenju sa Planomicrobium sp. RNP01, a dobijeni rezultati su potvrđeni gasno-hromatogafskom-FID analizom. Dehidrogenazna aktivnost soja Rhodococcus sp. RNP05 bila je viša u odnosu na Planomicrobium sp. RNP01 (r = 0,9995, P < 0,05) i u pozitivnoj korelaciji sa testom rasta na ugljovodonicima (r = 0,999, P < 0,05, za Rhodococcus sp. RNP05, r = 0,986, P < 0,05 za Planomicrobium sp. RNP01). Rezultati prikazanog istraživanja ukazuju na to da se kombinacija ovih testova može koristiti za određivanje bioremedijacionog potencijala za razgradnju PAH jedinjenja u zemljištu zagađenim naftom, pri čemu se dobija i mogućnost testiranja velikog broja bakterijskih sojeva.",
publisher = "Savez hemijskih inženjera Srbije, Beograd",
journal = "Chemical Industry and Chemical Engineering Quarterly",
title = "Evaluation of assays for screening polycyclic aromatic hydrocarbon-degrading potential of bacteria",
volume = "26",
number = "1",
pages = "41-48",
doi = "10.2298/CICEQ190220023L"
}

Lješević, M., Milić, J., Gojgić-Cvijović, G., Šolević Knudsen, T., Ilić, M., Avdalović, J.,& Vrvić, M.. (2020). Evaluation of assays for screening polycyclic aromatic hydrocarbon-degrading potential of bacteria. in Chemical Industry and Chemical Engineering Quarterly
Savez hemijskih inženjera Srbije, Beograd., 26(1), 41-48.
https://doi.org/10.2298/CICEQ190220023L

Lješević M, Milić J, Gojgić-Cvijović G, Šolević Knudsen T, Ilić M, Avdalović J, Vrvić M. Evaluation of assays for screening polycyclic aromatic hydrocarbon-degrading potential of bacteria. in Chemical Industry and Chemical Engineering Quarterly. 2020;26(1):41-48.
doi:10.2298/CICEQ190220023L .

Lješević, Marija, Milić, Jelena, Gojgić-Cvijović, Gordana, Šolević Knudsen, Tatjana, Ilić, Mila, Avdalović, Jelena, Vrvić, Miroslav, "Evaluation of assays for screening polycyclic aromatic hydrocarbon-degrading potential of bacteria" in Chemical Industry and Chemical Engineering Quarterly, 26, no. 1 (2020):41-48,
https://doi.org/10.2298/CICEQ190220023L . .

TY  - JOUR
AU  - Miletić, Srđan
AU  - Avdalović, Jelena
AU  - Milić, Jelena
AU  - Ilić, Mila
AU  - Žerađanin, Aleksandra
AU  - Joksimović, Kristina
AU  - Spasić, Snežana
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3934
AB  - Humic acids isolated from the soil of a heat power plant (HA-E) contaminated with oil were analyzed by Fourier transform infrared spectroscopy (FTIR). In comparison with a humic acids standard (HA-S), a lack of an intense broad band of the stretching vibrations of hydrogen-bonded hydroxyl groups (3600–3200 cm-1) is evident. The HA-E spectra have a peak at 1649 cm-1, which could belong to carbonyl groups. HA-E are heavily oxidized and among the isolated microorganisms, Achromobacter denitrificans may be responsible for such intensive oxidation of HA-E. To the phylogenetically diverse nitrate-reducing microorganisms that have the capacity to utilize reduced HA as electron donors in soils, A. denitrificans can be added.
AB  - Хуминске киселине, изоловане из земљишта контаминираног нафтом из топлане (HA-E) је анализирано уз помоћ инфрацрвеног спектрометра (FTIR). У поређењу са стандардом хуминских киселина (HA-S) уочљив је недостатак интензивног пика вибрација водоничне везе из хидоксилне групе (3600–3200 cm-1). HA-E има пик на 1649 cm-1 који вероватно припада карбонилној групи. HA-E су веома оксидоване, а претпоставља се да су микроорганизми Achromobacter denitrificans за ову интензивну оксидацију HA-E. Они су филогенетски различити нитрат-редукујући микроорганизми који имају капацитет да редукују хуминске киселине где се понашају као електрон донори у земљишту.
PB  - Serbia : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Oxidized humic acids from the soil of heat power plant
T1  - Oksidovane huminske kiseline iz toplane
VL  - 85
IS  - 3
SP  - 421
EP  - 426
DO  - 10.2298/JSC190726099M
ER  - 

@article{
author = "Miletić, Srđan and Avdalović, Jelena and Milić, Jelena and Ilić, Mila and Žerađanin, Aleksandra and Joksimović, Kristina and Spasić, Snežana",
year = "2020",
abstract = "Humic acids isolated from the soil of a heat power plant (HA-E) contaminated with oil were analyzed by Fourier transform infrared spectroscopy (FTIR). In comparison with a humic acids standard (HA-S), a lack of an intense broad band of the stretching vibrations of hydrogen-bonded hydroxyl groups (3600–3200 cm-1) is evident. The HA-E spectra have a peak at 1649 cm-1, which could belong to carbonyl groups. HA-E are heavily oxidized and among the isolated microorganisms, Achromobacter denitrificans may be responsible for such intensive oxidation of HA-E. To the phylogenetically diverse nitrate-reducing microorganisms that have the capacity to utilize reduced HA as electron donors in soils, A. denitrificans can be added., Хуминске киселине, изоловане из земљишта контаминираног нафтом из топлане (HA-E) је анализирано уз помоћ инфрацрвеног спектрометра (FTIR). У поређењу са стандардом хуминских киселина (HA-S) уочљив је недостатак интензивног пика вибрација водоничне везе из хидоксилне групе (3600–3200 cm-1). HA-E има пик на 1649 cm-1 који вероватно припада карбонилној групи. HA-E су веома оксидоване, а претпоставља се да су микроорганизми Achromobacter denitrificans за ову интензивну оксидацију HA-E. Они су филогенетски различити нитрат-редукујући микроорганизми који имају капацитет да редукују хуминске киселине где се понашају као електрон донори у земљишту.",
publisher = "Serbia : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Oxidized humic acids from the soil of heat power plant, Oksidovane huminske kiseline iz toplane",
volume = "85",
number = "3",
pages = "421-426",
doi = "10.2298/JSC190726099M"
}

Miletić, S., Avdalović, J., Milić, J., Ilić, M., Žerađanin, A., Joksimović, K.,& Spasić, S.. (2020). Oxidized humic acids from the soil of heat power plant. in Journal of the Serbian Chemical Society
Serbia : Serbian Chemical Society., 85(3), 421-426.
https://doi.org/10.2298/JSC190726099M

Miletić S, Avdalović J, Milić J, Ilić M, Žerađanin A, Joksimović K, Spasić S. Oxidized humic acids from the soil of heat power plant. in Journal of the Serbian Chemical Society. 2020;85(3):421-426.
doi:10.2298/JSC190726099M .

Miletić, Srđan, Avdalović, Jelena, Milić, Jelena, Ilić, Mila, Žerađanin, Aleksandra, Joksimović, Kristina, Spasić, Snežana, "Oxidized humic acids from the soil of heat power plant" in Journal of the Serbian Chemical Society, 85, no. 3 (2020):421-426,
https://doi.org/10.2298/JSC190726099M . .

TY  - JOUR
AU  - Pantelić, Ivana
AU  - Lukić, Milica
AU  - Gojgić-Cvijović, Gordana
AU  - Jakovljević, Dragica
AU  - Nikolić, Ines
AU  - Jasmin Lunterc, Dominique
AU  - Daniels, Rolf
AU  - Savić, Snežana D.
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3349
AB  - Ongoing demand in sustainable and biocompatible drug dosage forms is reflected in the search for novel pharmaceutical excipients with equal properties. A group of microbial exopolysaccharides offers a variety of biopolymers with many alleged uses and effects. This study aims to assess applicative properties of levan obtained from Bacillus licheniformis NS032, focusing on its potential co-stabilizing and drug release-controlling functions in pertaining emulsion systems. Despite its high molecular weight and partial existence in globular nanometric structures (180-190 nm), levan was successfully incorporated into both tested colloidal systems: those stabilized with synthetic/anionic or natural-origin/non-ionic emulsifiers. In the tested levan concentrations range (0.2-3.0% w/w) the monitored flow and thermal parameters failed to show linear concentration dependence, which prompted us to revisit certain colloidal fundamentals of this biopolymer. Being a part of the external phase of the investigated emulsion systems, levan contributed to formation of a matrix-like environment, offering additional stabilization of the microstructure and rheology modifying properties (hysteresis loop elevation as high as 4167±98 to 20792±3166 Pa•s−1), especially in case of the samples where lamellar liquid crystalline formation occurred. Apart from its good water solubility and considerable conformational flexibility, the investigated homofructan easily saturated the external phase of the samples stabilized with a conventional anionic emulsifier, leading to similar properties of 0.2% and 3.0% levan-containing samples. After closer consideration of thermal and release behavior, this was considered as a favorable property for a novel excipient, offering tailored formulation characteristics even with lower levan concentrations, consequently not compromising the potential cost of the final drug dosage form.
PB  - Elsevier
T2  - European Journal of Pharmaceutical Sciences
T1  - Bacillus licheniformis levan as a functional biopolymer in topical drug dosage forms: From basic colloidal considerations to actual pharmaceutical application
VL  - 142
SP  - 105109
DO  - 10.1016/j.ejps.2019.105109
ER  - 

@article{
author = "Pantelić, Ivana and Lukić, Milica and Gojgić-Cvijović, Gordana and Jakovljević, Dragica and Nikolić, Ines and Jasmin Lunterc, Dominique and Daniels, Rolf and Savić, Snežana D.",
year = "2020",
abstract = "Ongoing demand in sustainable and biocompatible drug dosage forms is reflected in the search for novel pharmaceutical excipients with equal properties. A group of microbial exopolysaccharides offers a variety of biopolymers with many alleged uses and effects. This study aims to assess applicative properties of levan obtained from Bacillus licheniformis NS032, focusing on its potential co-stabilizing and drug release-controlling functions in pertaining emulsion systems. Despite its high molecular weight and partial existence in globular nanometric structures (180-190 nm), levan was successfully incorporated into both tested colloidal systems: those stabilized with synthetic/anionic or natural-origin/non-ionic emulsifiers. In the tested levan concentrations range (0.2-3.0% w/w) the monitored flow and thermal parameters failed to show linear concentration dependence, which prompted us to revisit certain colloidal fundamentals of this biopolymer. Being a part of the external phase of the investigated emulsion systems, levan contributed to formation of a matrix-like environment, offering additional stabilization of the microstructure and rheology modifying properties (hysteresis loop elevation as high as 4167±98 to 20792±3166 Pa•s−1), especially in case of the samples where lamellar liquid crystalline formation occurred. Apart from its good water solubility and considerable conformational flexibility, the investigated homofructan easily saturated the external phase of the samples stabilized with a conventional anionic emulsifier, leading to similar properties of 0.2% and 3.0% levan-containing samples. After closer consideration of thermal and release behavior, this was considered as a favorable property for a novel excipient, offering tailored formulation characteristics even with lower levan concentrations, consequently not compromising the potential cost of the final drug dosage form.",
publisher = "Elsevier",
journal = "European Journal of Pharmaceutical Sciences",
title = "Bacillus licheniformis levan as a functional biopolymer in topical drug dosage forms: From basic colloidal considerations to actual pharmaceutical application",
volume = "142",
pages = "105109",
doi = "10.1016/j.ejps.2019.105109"
}

Pantelić, I., Lukić, M., Gojgić-Cvijović, G., Jakovljević, D., Nikolić, I., Jasmin Lunterc, D., Daniels, R.,& Savić, S. D.. (2020). Bacillus licheniformis levan as a functional biopolymer in topical drug dosage forms: From basic colloidal considerations to actual pharmaceutical application. in European Journal of Pharmaceutical Sciences
Elsevier., 142, 105109.
https://doi.org/10.1016/j.ejps.2019.105109

Pantelić I, Lukić M, Gojgić-Cvijović G, Jakovljević D, Nikolić I, Jasmin Lunterc D, Daniels R, Savić SD. Bacillus licheniformis levan as a functional biopolymer in topical drug dosage forms: From basic colloidal considerations to actual pharmaceutical application. in European Journal of Pharmaceutical Sciences. 2020;142:105109.
doi:10.1016/j.ejps.2019.105109 .

Pantelić, Ivana, Lukić, Milica, Gojgić-Cvijović, Gordana, Jakovljević, Dragica, Nikolić, Ines, Jasmin Lunterc, Dominique, Daniels, Rolf, Savić, Snežana D., "Bacillus licheniformis levan as a functional biopolymer in topical drug dosage forms: From basic colloidal considerations to actual pharmaceutical application" in European Journal of Pharmaceutical Sciences, 142 (2020):105109,
https://doi.org/10.1016/j.ejps.2019.105109 . .

TY  - JOUR
AU  - Kop, Tatjana
AU  - Jakovljević, Dragica
AU  - Živković, Ljiljana S.
AU  - Žekić, Andrijana
AU  - Beškoski, Vladimir
AU  - Milić, Dragana
AU  - Gojgić-Cvijović, Gordana
AU  - Bjelaković, Mira
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3332
AB  - An efficient encapsulation of the fullerene into two hydrophobized and one native polysaccharide provided water soluble supramolecular hybrids. After covalent modification of polysaccharides by cholesterol, noncovalent hybrids were prepared by a three-step procedure, including mixing of individual aqueous solutions of hydrophobized, as well as native sugar with solution of the fullerene in pyridine, dialysis and lyophilization. Although the degree of the fullerene incorporation into hydrophobized substrates, cholesterol-levan and cholesterol-pullulan, was lower in comparison to the native polysaccharide levan, hydrophobization provided nanoparticles with improved properties. The particle size distribution, studied by dynamic light scattering and scanning electron microscopy revealed formation of moderately polydisperse aggregates, with the diameter contraction in comparison to the corresponding free polysaccharide, especially in the case of hydrophobized substrates. The morphological examination, done by scanning electron microscopy indicated the self-organization of the fullerene-native polysaccharide to round individual structures, while fullerene-hydrophobized polysaccharide hybrids tend to form networks. The antioxidant activity of the synthesized polysaccharide-C60 noncovalent hybrids versus starting polysaccharides was investigated by the DPPH radical scavenging and the β-carotene-linoleic acid bleaching methods. In all three complexes, the radical scavenging ability of the fullerene remained preserved, and a positive effect of levan hydrophobization was observed.
PB  - Elsevier
T2  - European Polymer Journal
T1  - Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity
VL  - 123
SP  - 109461
DO  - 10.1016/j.eurpolymj.2019.109461
ER  - 

@article{
author = "Kop, Tatjana and Jakovljević, Dragica and Živković, Ljiljana S. and Žekić, Andrijana and Beškoski, Vladimir and Milić, Dragana and Gojgić-Cvijović, Gordana and Bjelaković, Mira",
year = "2020",
abstract = "An efficient encapsulation of the fullerene into two hydrophobized and one native polysaccharide provided water soluble supramolecular hybrids. After covalent modification of polysaccharides by cholesterol, noncovalent hybrids were prepared by a three-step procedure, including mixing of individual aqueous solutions of hydrophobized, as well as native sugar with solution of the fullerene in pyridine, dialysis and lyophilization. Although the degree of the fullerene incorporation into hydrophobized substrates, cholesterol-levan and cholesterol-pullulan, was lower in comparison to the native polysaccharide levan, hydrophobization provided nanoparticles with improved properties. The particle size distribution, studied by dynamic light scattering and scanning electron microscopy revealed formation of moderately polydisperse aggregates, with the diameter contraction in comparison to the corresponding free polysaccharide, especially in the case of hydrophobized substrates. The morphological examination, done by scanning electron microscopy indicated the self-organization of the fullerene-native polysaccharide to round individual structures, while fullerene-hydrophobized polysaccharide hybrids tend to form networks. The antioxidant activity of the synthesized polysaccharide-C60 noncovalent hybrids versus starting polysaccharides was investigated by the DPPH radical scavenging and the β-carotene-linoleic acid bleaching methods. In all three complexes, the radical scavenging ability of the fullerene remained preserved, and a positive effect of levan hydrophobization was observed.",
publisher = "Elsevier",
journal = "European Polymer Journal",
title = "Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity",
volume = "123",
pages = "109461",
doi = "10.1016/j.eurpolymj.2019.109461"
}

Kop, T., Jakovljević, D., Živković, L. S., Žekić, A., Beškoski, V., Milić, D., Gojgić-Cvijović, G.,& Bjelaković, M.. (2020). Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity. in European Polymer Journal
Elsevier., 123, 109461.
https://doi.org/10.1016/j.eurpolymj.2019.109461

Kop T, Jakovljević D, Živković LS, Žekić A, Beškoski V, Milić D, Gojgić-Cvijović G, Bjelaković M. Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity. in European Polymer Journal. 2020;123:109461.
doi:10.1016/j.eurpolymj.2019.109461 .

Kop, Tatjana, Jakovljević, Dragica, Živković, Ljiljana S., Žekić, Andrijana, Beškoski, Vladimir, Milić, Dragana, Gojgić-Cvijović, Gordana, Bjelaković, Mira, "Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity" in European Polymer Journal, 123 (2020):109461,
https://doi.org/10.1016/j.eurpolymj.2019.109461 . .

TY  - JOUR
AU  - Kop, Tatjana
AU  - Jakovljević, Dragica
AU  - Živković, Ljiljana S.
AU  - Žekić, Andrijana
AU  - Beškoski, Vladimir
AU  - Milić, Dragana
AU  - Gojgić-Cvijović, Gordana
AU  - Bjelaković, Mira
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3336
AB  - An efficient encapsulation of the fullerene into two hydrophobized and one native polysaccharide provided water soluble supramolecular hybrids. After covalent modification of polysaccharides by cholesterol, noncovalent hybrids were prepared by a three-step procedure, including mixing of individual aqueous solutions of hydrophobized, as well as native sugar with solution of the fullerene in pyridine, dialysis and lyophilization. Although the degree of the fullerene incorporation into hydrophobized substrates, cholesterol-levan and cholesterol-pullulan, was lower in comparison to the native polysaccharide levan, hydrophobization provided nanoparticles with improved properties. The particle size distribution, studied by dynamic light scattering and scanning electron microscopy revealed formation of moderately polydisperse aggregates, with the diameter contraction in comparison to the corresponding free polysaccharide, especially in the case of hydrophobized substrates. The morphological examination, done by scanning electron microscopy indicated the self-organization of the fullerene-native polysaccharide to round individual structures, while fullerene-hydrophobized polysaccharide hybrids tend to form networks. The antioxidant activity of the synthesized polysaccharide-C60 noncovalent hybrids versus starting polysaccharides was investigated by the DPPH radical scavenging and the β-carotene-linoleic acid bleaching methods. In all three complexes, the radical scavenging ability of the fullerene remained preserved, and a positive effect of levan hydrophobization was observed.
PB  - Elsevier
T2  - European Polymer Journal
T1  - Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity
VL  - 123
SP  - 109461
DO  - 10.1016/j.eurpolymj.2019.109461
ER  - 

@article{
author = "Kop, Tatjana and Jakovljević, Dragica and Živković, Ljiljana S. and Žekić, Andrijana and Beškoski, Vladimir and Milić, Dragana and Gojgić-Cvijović, Gordana and Bjelaković, Mira",
year = "2020",
abstract = "An efficient encapsulation of the fullerene into two hydrophobized and one native polysaccharide provided water soluble supramolecular hybrids. After covalent modification of polysaccharides by cholesterol, noncovalent hybrids were prepared by a three-step procedure, including mixing of individual aqueous solutions of hydrophobized, as well as native sugar with solution of the fullerene in pyridine, dialysis and lyophilization. Although the degree of the fullerene incorporation into hydrophobized substrates, cholesterol-levan and cholesterol-pullulan, was lower in comparison to the native polysaccharide levan, hydrophobization provided nanoparticles with improved properties. The particle size distribution, studied by dynamic light scattering and scanning electron microscopy revealed formation of moderately polydisperse aggregates, with the diameter contraction in comparison to the corresponding free polysaccharide, especially in the case of hydrophobized substrates. The morphological examination, done by scanning electron microscopy indicated the self-organization of the fullerene-native polysaccharide to round individual structures, while fullerene-hydrophobized polysaccharide hybrids tend to form networks. The antioxidant activity of the synthesized polysaccharide-C60 noncovalent hybrids versus starting polysaccharides was investigated by the DPPH radical scavenging and the β-carotene-linoleic acid bleaching methods. In all three complexes, the radical scavenging ability of the fullerene remained preserved, and a positive effect of levan hydrophobization was observed.",
publisher = "Elsevier",
journal = "European Polymer Journal",
title = "Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity",
volume = "123",
pages = "109461",
doi = "10.1016/j.eurpolymj.2019.109461"
}

Kop, T., Jakovljević, D., Živković, L. S., Žekić, A., Beškoski, V., Milić, D., Gojgić-Cvijović, G.,& Bjelaković, M.. (2020). Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity. in European Polymer Journal
Elsevier., 123, 109461.
https://doi.org/10.1016/j.eurpolymj.2019.109461

Kop T, Jakovljević D, Živković LS, Žekić A, Beškoski V, Milić D, Gojgić-Cvijović G, Bjelaković M. Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity. in European Polymer Journal. 2020;123:109461.
doi:10.1016/j.eurpolymj.2019.109461 .

Kop, Tatjana, Jakovljević, Dragica, Živković, Ljiljana S., Žekić, Andrijana, Beškoski, Vladimir, Milić, Dragana, Gojgić-Cvijović, Gordana, Bjelaković, Mira, "Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity" in European Polymer Journal, 123 (2020):109461,
https://doi.org/10.1016/j.eurpolymj.2019.109461 . .

TY  - JOUR
AU  - Marković, Marijana
AU  - Anđelković, Ivan
AU  - Shuster, Jeremiah
AU  - Janik, Leslie
AU  - Kumar, Anupama
AU  - Lošić, Dušan
AU  - McLaughlin, Michael J.
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3346
AB  - The graphene oxide (GO) due to its exceptional structure, physicochemical and mechanical properties is a very attractive material for industry application. Even though, the unique properties of GO (e.g. structure, size, shape, etc.) make the risk assessment of this nanomaterial very challenging in comparison with conventional ecotoxicology studies required by regulators. Thus, there is a need for standardized characterization techniques and methodology to secure a high quality/reliable data on the ecotoxicology of GO, and to establish environmentally acceptable levels. Herein, authors address the crucial quality criteria when evaluating the ecotoxicology of GO using an algae (Raphidocelis subcapitata) and a shrimp (Paratya australiensis). This study provides a detail characterization and modification of the used GO, robust quantification and a suspension stability in different media for ecotoxicology studies. It was observed that under the same exposure conditions the behavior of GO and the estimated outcomes (IC50 values) in modified algae media differed in comparison to the referent media. Further to that, the adverse effects of GO on the algae cell structure and the potential uptake of GO by the algae cells were examined using the TEM with different staining techniques to avoid artefacts. Shrimps which were exposed to GO-algae aggregates via the food intake did not indicate stress or accumulation of GO. Our work presents an important insight to necessity of establishing a benchmark ecotoxicology assays for GO (e.g. characterization techniques, choice of media, etc.) and providing a reliable data to be used by regulators in risk assessment of two-dimensional (2D) nanomaterials.
PB  - Elsevier
T2  - Chemosphere
T1  - Addressing challenges in providing a reliable ecotoxicology data for graphene-oxide (GO) using an algae (Raphidocelis subcapitata), and the trophic transfer consequence of GO-algae aggregates
VL  - 245
SP  - 125640
DO  - 10.1016/j.chemosphere.2019.125640
ER  - 

@article{
author = "Marković, Marijana and Anđelković, Ivan and Shuster, Jeremiah and Janik, Leslie and Kumar, Anupama and Lošić, Dušan and McLaughlin, Michael J.",
year = "2020",
abstract = "The graphene oxide (GO) due to its exceptional structure, physicochemical and mechanical properties is a very attractive material for industry application. Even though, the unique properties of GO (e.g. structure, size, shape, etc.) make the risk assessment of this nanomaterial very challenging in comparison with conventional ecotoxicology studies required by regulators. Thus, there is a need for standardized characterization techniques and methodology to secure a high quality/reliable data on the ecotoxicology of GO, and to establish environmentally acceptable levels. Herein, authors address the crucial quality criteria when evaluating the ecotoxicology of GO using an algae (Raphidocelis subcapitata) and a shrimp (Paratya australiensis). This study provides a detail characterization and modification of the used GO, robust quantification and a suspension stability in different media for ecotoxicology studies. It was observed that under the same exposure conditions the behavior of GO and the estimated outcomes (IC50 values) in modified algae media differed in comparison to the referent media. Further to that, the adverse effects of GO on the algae cell structure and the potential uptake of GO by the algae cells were examined using the TEM with different staining techniques to avoid artefacts. Shrimps which were exposed to GO-algae aggregates via the food intake did not indicate stress or accumulation of GO. Our work presents an important insight to necessity of establishing a benchmark ecotoxicology assays for GO (e.g. characterization techniques, choice of media, etc.) and providing a reliable data to be used by regulators in risk assessment of two-dimensional (2D) nanomaterials.",
publisher = "Elsevier",
journal = "Chemosphere",
title = "Addressing challenges in providing a reliable ecotoxicology data for graphene-oxide (GO) using an algae (Raphidocelis subcapitata), and the trophic transfer consequence of GO-algae aggregates",
volume = "245",
pages = "125640",
doi = "10.1016/j.chemosphere.2019.125640"
}

Marković, M., Anđelković, I., Shuster, J., Janik, L., Kumar, A., Lošić, D.,& McLaughlin, M. J.. (2020). Addressing challenges in providing a reliable ecotoxicology data for graphene-oxide (GO) using an algae (Raphidocelis subcapitata), and the trophic transfer consequence of GO-algae aggregates. in Chemosphere
Elsevier., 245, 125640.
https://doi.org/10.1016/j.chemosphere.2019.125640

Marković M, Anđelković I, Shuster J, Janik L, Kumar A, Lošić D, McLaughlin MJ. Addressing challenges in providing a reliable ecotoxicology data for graphene-oxide (GO) using an algae (Raphidocelis subcapitata), and the trophic transfer consequence of GO-algae aggregates. in Chemosphere. 2020;245:125640.
doi:10.1016/j.chemosphere.2019.125640 .

Marković, Marijana, Anđelković, Ivan, Shuster, Jeremiah, Janik, Leslie, Kumar, Anupama, Lošić, Dušan, McLaughlin, Michael J., "Addressing challenges in providing a reliable ecotoxicology data for graphene-oxide (GO) using an algae (Raphidocelis subcapitata), and the trophic transfer consequence of GO-algae aggregates" in Chemosphere, 245 (2020):125640,
https://doi.org/10.1016/j.chemosphere.2019.125640 . .

TY  - CONF
AU  - Jednak, Tanja
AU  - Vrvić, Miroslav
AU  - Miletić, Srđan
AU  - Avdalović, Jelena
AU  - Ilić, Mila
AU  - Milić, Jelena
AU  - Beškoski, Vladimir
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4962
AB  - Contamination of soil, groundwater, sediment, surface water and air, hazardous waste such as oil and by-products
arising during processing of oil, pose a major problem the world faces today.
Catalysts used in the desulphurisation process oil can be a source of pollution with heavy metals and are therefore
tested their chemical properties, as well as their impact on the growth of microbial consortium in the process of bioremediation, which is isolated from the waste of fuel oil from the PUC “Belgrade power plants” and waste motor oil. We
examined five different catalysts that are derived from the Oil Refinery Pancevo, a metal that is focused attention as
Mo (molybdenum) and Co (cobalt).
The efficiency of bacterial cells in concentrating metal has enabled their high ratio of surface area to volume and high
charge density on the cell surface. Entire bacterial cell is negatively charged due to the presence of different anions.
Therefore, the bacterial cell walls have a strong affinity for metal cations. Intact bacterial cells, regardless of whether
they are alive or dead, as their products are also very effective in accumulating metals.
PB  - Federation of European Microbiological Societies (FEMS)
C3  - Electronic abstract book - FEMS online Conference on Microbiology
T1  - Investigation of Inhibitory Effect of Molybdenum and Cobalt in the Isolated Microorganism Consortia Which is Used in Bioremediation
SP  - 456
UR  - https://hdl.handle.net/21.15107/rcub_cer_4962
ER  - 

@conference{
author = "Jednak, Tanja and Vrvić, Miroslav and Miletić, Srđan and Avdalović, Jelena and Ilić, Mila and Milić, Jelena and Beškoski, Vladimir",
year = "2020",
abstract = "Contamination of soil, groundwater, sediment, surface water and air, hazardous waste such as oil and by-products
arising during processing of oil, pose a major problem the world faces today.
Catalysts used in the desulphurisation process oil can be a source of pollution with heavy metals and are therefore
tested their chemical properties, as well as their impact on the growth of microbial consortium in the process of bioremediation, which is isolated from the waste of fuel oil from the PUC “Belgrade power plants” and waste motor oil. We
examined five different catalysts that are derived from the Oil Refinery Pancevo, a metal that is focused attention as
Mo (molybdenum) and Co (cobalt).
The efficiency of bacterial cells in concentrating metal has enabled their high ratio of surface area to volume and high
charge density on the cell surface. Entire bacterial cell is negatively charged due to the presence of different anions.
Therefore, the bacterial cell walls have a strong affinity for metal cations. Intact bacterial cells, regardless of whether
they are alive or dead, as their products are also very effective in accumulating metals.",
publisher = "Federation of European Microbiological Societies (FEMS)",
journal = "Electronic abstract book - FEMS online Conference on Microbiology",
title = "Investigation of Inhibitory Effect of Molybdenum and Cobalt in the Isolated Microorganism Consortia Which is Used in Bioremediation",
pages = "456",
url = "https://hdl.handle.net/21.15107/rcub_cer_4962"
}

Jednak, T., Vrvić, M., Miletić, S., Avdalović, J., Ilić, M., Milić, J.,& Beškoski, V.. (2020). Investigation of Inhibitory Effect of Molybdenum and Cobalt in the Isolated Microorganism Consortia Which is Used in Bioremediation. in Electronic abstract book - FEMS online Conference on Microbiology
Federation of European Microbiological Societies (FEMS)., 456.
https://hdl.handle.net/21.15107/rcub_cer_4962

Jednak T, Vrvić M, Miletić S, Avdalović J, Ilić M, Milić J, Beškoski V. Investigation of Inhibitory Effect of Molybdenum and Cobalt in the Isolated Microorganism Consortia Which is Used in Bioremediation. in Electronic abstract book - FEMS online Conference on Microbiology. 2020;:456.
https://hdl.handle.net/21.15107/rcub_cer_4962 .

Jednak, Tanja, Vrvić, Miroslav, Miletić, Srđan, Avdalović, Jelena, Ilić, Mila, Milić, Jelena, Beškoski, Vladimir, "Investigation of Inhibitory Effect of Molybdenum and Cobalt in the Isolated Microorganism Consortia Which is Used in Bioremediation" in Electronic abstract book - FEMS online Conference on Microbiology (2020):456,
https://hdl.handle.net/21.15107/rcub_cer_4962 .

TY  - CONF
AU  - Jednak, Tanja
AU  - Vrvić, Miroslav
AU  - Miletić, Srđan
AU  - Avdalović, Jelena
AU  - Ilić, Mila
AU  - Milić, Jelena
AU  - Beškoski, Vladimir
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4963
AB  - Poster presented at: FEMS online Conference on Microbiology, 28 – 31 October 2020
T1  - Investigation of Inhibitory Effect of Molybdenum and Cobalt in the Isolated Microorganism Consortia Which is Used in Bioremediation
UR  - https://hdl.handle.net/21.15107/rcub_cer_4963
ER  - 

@conference{
author = "Jednak, Tanja and Vrvić, Miroslav and Miletić, Srđan and Avdalović, Jelena and Ilić, Mila and Milić, Jelena and Beškoski, Vladimir",
year = "2020",
abstract = "Poster presented at: FEMS online Conference on Microbiology, 28 – 31 October 2020",
title = "Investigation of Inhibitory Effect of Molybdenum and Cobalt in the Isolated Microorganism Consortia Which is Used in Bioremediation",
url = "https://hdl.handle.net/21.15107/rcub_cer_4963"
}

Jednak, T., Vrvić, M., Miletić, S., Avdalović, J., Ilić, M., Milić, J.,& Beškoski, V.. (2020). Investigation of Inhibitory Effect of Molybdenum and Cobalt in the Isolated Microorganism Consortia Which is Used in Bioremediation. .
https://hdl.handle.net/21.15107/rcub_cer_4963

Jednak T, Vrvić M, Miletić S, Avdalović J, Ilić M, Milić J, Beškoski V. Investigation of Inhibitory Effect of Molybdenum and Cobalt in the Isolated Microorganism Consortia Which is Used in Bioremediation. 2020;.
https://hdl.handle.net/21.15107/rcub_cer_4963 .

Jednak, Tanja, Vrvić, Miroslav, Miletić, Srđan, Avdalović, Jelena, Ilić, Mila, Milić, Jelena, Beškoski, Vladimir, "Investigation of Inhibitory Effect of Molybdenum and Cobalt in the Isolated Microorganism Consortia Which is Used in Bioremediation" (2020),
https://hdl.handle.net/21.15107/rcub_cer_4963 .

TY  - JOUR
AU  - Medić, Ana
AU  - Lješević, Marija
AU  - Inui, Hideyuku
AU  - Beškoski, Vladimir
AU  - Kojić, Ivan
AU  - Stojanović, Ksenija
AU  - Karadžić, Ivanka
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3576
AB  - Pseudomonas aeruginosa san ai, an alkaliphilic, metallotolerant bacterium, degraded individual selected
petroleum compounds, i.e., n-alkanes (n-hexadecane, n-nonadecane) and polycyclic aromatic
hydrocarbons (fluorene, phenanthrene, pyrene) with efficiency of 80%, 98%, 96%, 50% and 41%,
respectively, at initial concentrations of 20 mg L 1 and in seven days. P. aeruginosa san ai showed a high
biodegradative capacity on complex hydrocarbon mixtures, the aliphatic and aromatic fractions from
crude oil. The efficiency of P. aeruginosa san ai degradation of crude oil fractions in seven days reached
stage 3–4 of the oil biodegradation scale, which ranges from 0 (no biodegradation) to 10 (maximum
biodegradation). Identified metabolites concomitant with genomic and enzymatic data indicated the
terminal oxidation pathway for the n-alkane degradation, and the salicylate and phthalate pathways for
fluorene biodegradation. Polyextremophilic P. aeruginosa san ai, as a biosurfactant producer with
multidegradative capacity for hydrocarbons, can be used in an improved strategy for environmental
bioremediation of hydrocarbon-contaminated sites, including extreme habitats characterized by low or
elevated temperatures, acidic or alkaline pH or high concentrations of heavy metals.
PB  - Royal Society  of Chemistry
T2  - RSC Advances
T1  - Efficient biodegradation of petroleum n-alkanes and polycyclic aromatic hydrocarbons by polyextremophilic Pseudomonas aeruginosa san ai with multidegradative capacity
VL  - 10
IS  - 24
SP  - 14060
EP  - 14070
DO  - 10.1039/c9ra10371f
ER  - 

@article{
author = "Medić, Ana and Lješević, Marija and Inui, Hideyuku and Beškoski, Vladimir and Kojić, Ivan and Stojanović, Ksenija and Karadžić, Ivanka",
year = "2020",
abstract = "Pseudomonas aeruginosa san ai, an alkaliphilic, metallotolerant bacterium, degraded individual selected
petroleum compounds, i.e., n-alkanes (n-hexadecane, n-nonadecane) and polycyclic aromatic
hydrocarbons (fluorene, phenanthrene, pyrene) with efficiency of 80%, 98%, 96%, 50% and 41%,
respectively, at initial concentrations of 20 mg L 1 and in seven days. P. aeruginosa san ai showed a high
biodegradative capacity on complex hydrocarbon mixtures, the aliphatic and aromatic fractions from
crude oil. The efficiency of P. aeruginosa san ai degradation of crude oil fractions in seven days reached
stage 3–4 of the oil biodegradation scale, which ranges from 0 (no biodegradation) to 10 (maximum
biodegradation). Identified metabolites concomitant with genomic and enzymatic data indicated the
terminal oxidation pathway for the n-alkane degradation, and the salicylate and phthalate pathways for
fluorene biodegradation. Polyextremophilic P. aeruginosa san ai, as a biosurfactant producer with
multidegradative capacity for hydrocarbons, can be used in an improved strategy for environmental
bioremediation of hydrocarbon-contaminated sites, including extreme habitats characterized by low or
elevated temperatures, acidic or alkaline pH or high concentrations of heavy metals.",
publisher = "Royal Society  of Chemistry",
journal = "RSC Advances",
title = "Efficient biodegradation of petroleum n-alkanes and polycyclic aromatic hydrocarbons by polyextremophilic Pseudomonas aeruginosa san ai with multidegradative capacity",
volume = "10",
number = "24",
pages = "14060-14070",
doi = "10.1039/c9ra10371f"
}

Medić, A., Lješević, M., Inui, H., Beškoski, V., Kojić, I., Stojanović, K.,& Karadžić, I.. (2020). Efficient biodegradation of petroleum n-alkanes and polycyclic aromatic hydrocarbons by polyextremophilic Pseudomonas aeruginosa san ai with multidegradative capacity. in RSC Advances
Royal Society  of Chemistry., 10(24), 14060-14070.
https://doi.org/10.1039/c9ra10371f

Medić A, Lješević M, Inui H, Beškoski V, Kojić I, Stojanović K, Karadžić I. Efficient biodegradation of petroleum n-alkanes and polycyclic aromatic hydrocarbons by polyextremophilic Pseudomonas aeruginosa san ai with multidegradative capacity. in RSC Advances. 2020;10(24):14060-14070.
doi:10.1039/c9ra10371f .

Medić, Ana, Lješević, Marija, Inui, Hideyuku, Beškoski, Vladimir, Kojić, Ivan, Stojanović, Ksenija, Karadžić, Ivanka, "Efficient biodegradation of petroleum n-alkanes and polycyclic aromatic hydrocarbons by polyextremophilic Pseudomonas aeruginosa san ai with multidegradative capacity" in RSC Advances, 10, no. 24 (2020):14060-14070,
https://doi.org/10.1039/c9ra10371f . .

TY  - JOUR
AU  - Žerađanin, Aleksandra
AU  - Avdalović, Jelena
AU  - Lješević, Marija
AU  - Tešić, Olivera
AU  - Miletić, Srđan
AU  - Vrvić, Miroslav
AU  - Beškoski, Vladimir
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3729
AB  - Environmental pollution is a global problem, while bioremediation technology removes pollutants from the environment using microorganisms. This study was aimed at investigating how a bioremediation process affected soil humification. In soil polluted with petroleum and its derivatives that was submitted to bioremediation, besides the total petroleum hydrocarbons and the number of microorganisms, quantitative and qualitative changes of isolated
humic acids were determined during the process. The bioremediation of 150 m3 of polluted soil lasted 150 days. The level of total petroleum hydrocarbons
decreased by 86.6 %, while the level of humic acids increased by 26.5 %. The elemental analysis showed the reduction of C and the H/C ratio and the
increase of O and the O/C ratio of isolated humic acids during the process. The ratio of absorbencies at 465 and 665 nm also increased. Based on this and the
Fourier-transform infrared spectra, it was shown that the humic acids isolated at the end of bioremediation were enriched with oxygen functional groups and
aromatic structures. This study provides one of the first insights into the relationship between bioremediation and humification, as well as evidence of how
hydrocarbon-degrading microorganisms have a significant influence on changes to humic acid structure during bioremediation.
AB  - Загађење животне средине представља светски проблем, а биоремедијација је  технологија којом се контаминанти уклањају из животне средине употребом  микроорганизама. Циљ овог рада био је да се испита како процес биоремедијације утиче на
 хумификацију. У земљишту загађеном нафтом и њеним дериватима које је подвргнуто процесу
биоремедијације, осим укупних нафтних угљоводоника и броја микроорганизама,
одређене су квантитативне и квалитативне промене изолованих хуминских киселина. Биоремедијација 150 m3 загађеног земљишта је трајала 150 дана. Количина укупних нафтних угљоводоника током биоремедијације смањена је за 86,6 %, док се ниво
 хуминских киселина повећао за 26,5 %. Елементарна анализа je показала смањење количине угљеника и H/C односа, али и повећање кисеоника и О/C односа у изолованим 
хуминским киселинама током процеса. Такође је повећан однос апсорбанци на 465 и 665 nm.
На основу ових резултата и инфрацрвених спектара показано је да су хуминске киселине са краја биоремедијације обогаћене функционалним групама кисеоника и  ароматичним структурама. Студија показује један од првих увида у однос између
 биоремедијације и хумификације, као и доказ да микроорганизми који разграђују  угљоводонике имају значајан утицај на структуру хуминских киселина.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Evolution of humic acids during ex situ bioremediation on a pilot level – The added value of the microbial activity
T1  - Nastanak huminskih kiselina tokom ex situ bioremedijacije na pilot nivou - dodata vrednost mikrobne aktivnosti
VL  - 85
IS  - 6
SP  - 821
EP  - 830
DO  - 10.2298/JSC190916131Z
ER  - 

@article{
author = "Žerađanin, Aleksandra and Avdalović, Jelena and Lješević, Marija and Tešić, Olivera and Miletić, Srđan and Vrvić, Miroslav and Beškoski, Vladimir",
year = "2020",
abstract = "Environmental pollution is a global problem, while bioremediation technology removes pollutants from the environment using microorganisms. This study was aimed at investigating how a bioremediation process affected soil humification. In soil polluted with petroleum and its derivatives that was submitted to bioremediation, besides the total petroleum hydrocarbons and the number of microorganisms, quantitative and qualitative changes of isolated
humic acids were determined during the process. The bioremediation of 150 m3 of polluted soil lasted 150 days. The level of total petroleum hydrocarbons
decreased by 86.6 %, while the level of humic acids increased by 26.5 %. The elemental analysis showed the reduction of C and the H/C ratio and the
increase of O and the O/C ratio of isolated humic acids during the process. The ratio of absorbencies at 465 and 665 nm also increased. Based on this and the
Fourier-transform infrared spectra, it was shown that the humic acids isolated at the end of bioremediation were enriched with oxygen functional groups and
aromatic structures. This study provides one of the first insights into the relationship between bioremediation and humification, as well as evidence of how
hydrocarbon-degrading microorganisms have a significant influence on changes to humic acid structure during bioremediation., Загађење животне средине представља светски проблем, а биоремедијација је  технологија којом се контаминанти уклањају из животне средине употребом  микроорганизама. Циљ овог рада био је да се испита како процес биоремедијације утиче на
 хумификацију. У земљишту загађеном нафтом и њеним дериватима које је подвргнуто процесу
биоремедијације, осим укупних нафтних угљоводоника и броја микроорганизама,
одређене су квантитативне и квалитативне промене изолованих хуминских киселина. Биоремедијација 150 m3 загађеног земљишта је трајала 150 дана. Количина укупних нафтних угљоводоника током биоремедијације смањена је за 86,6 %, док се ниво
 хуминских киселина повећао за 26,5 %. Елементарна анализа je показала смањење количине угљеника и H/C односа, али и повећање кисеоника и О/C односа у изолованим 
хуминским киселинама током процеса. Такође је повећан однос апсорбанци на 465 и 665 nm.
На основу ових резултата и инфрацрвених спектара показано је да су хуминске киселине са краја биоремедијације обогаћене функционалним групама кисеоника и  ароматичним структурама. Студија показује један од првих увида у однос између
 биоремедијације и хумификације, као и доказ да микроорганизми који разграђују  угљоводонике имају значајан утицај на структуру хуминских киселина.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Evolution of humic acids during ex situ bioremediation on a pilot level – The added value of the microbial activity, Nastanak huminskih kiselina tokom ex situ bioremedijacije na pilot nivou - dodata vrednost mikrobne aktivnosti",
volume = "85",
number = "6",
pages = "821-830",
doi = "10.2298/JSC190916131Z"
}

Žerađanin, A., Avdalović, J., Lješević, M., Tešić, O., Miletić, S., Vrvić, M.,& Beškoski, V.. (2020). Evolution of humic acids during ex situ bioremediation on a pilot level – The added value of the microbial activity. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 85(6), 821-830.
https://doi.org/10.2298/JSC190916131Z

Žerađanin A, Avdalović J, Lješević M, Tešić O, Miletić S, Vrvić M, Beškoski V. Evolution of humic acids during ex situ bioremediation on a pilot level – The added value of the microbial activity. in Journal of the Serbian Chemical Society. 2020;85(6):821-830.
doi:10.2298/JSC190916131Z .

Žerađanin, Aleksandra, Avdalović, Jelena, Lješević, Marija, Tešić, Olivera, Miletić, Srđan, Vrvić, Miroslav, Beškoski, Vladimir, "Evolution of humic acids during ex situ bioremediation on a pilot level – The added value of the microbial activity" in Journal of the Serbian Chemical Society, 85, no. 6 (2020):821-830,
https://doi.org/10.2298/JSC190916131Z . .

TY  - JOUR
AU  - Kozarski, Maja S.
AU  - Klaus, Anita
AU  - Vunduk, Jovana
AU  - Jakovljević, Dragica
AU  - Jadranin, Milka
AU  - Nikšić, Miomir
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3727
AB  - The health promoting effects of hot water extracts obtained from
fruiting bodies of the commercially cultivated mushroom Agaricus bisporus
(AbHW) and the wild-growing mushroom Ganoderma resinaceum (GrHW)
originating from northern Serbia are presented in this research. These abilities
were compared in vitro by the prevention of lipid peroxidation (LPx) in a linoleic
acid model system, inhibition of the angiotension converting I enzyme
(ACE) that could help in the maintenance of a normal blood pressure level and
strengthening the ability of the central cholinergic neuron by inhibiting the activity
of acetylcholinesterase (AChE). Cytotoxic activities were observed
towards selected human malignant (HeLa and K562) cell lines and normal-
-human peripheral blood mononuclear cells (PBMC). GrHW contains higher
phenolics (5.9 g (100 g)-1), inhibition of LPx (EC50 = 1.07 mg mL-1), ACE
(IC50 = 0.54 mg mL-1) and AChE (IC50 = 0.37 mg mL-1), and exhibited a significant
selectivity in the antitumour action against HeLa (IC50 = 0.14 mg mL-1)
and K562 (IC50 = 0.11 mg mL-1) cells. AbHW contained higher total protein
(6.4 g (100 g)-1), carbohydrate (75.4 g (100 g)-1) and β-glucan (55.1 g (100 g)-1)
contents and induced significant proliferation of healthy PBMC from 152–116
% in the concentration range of 0.047–0.187 mg mL-1. The difference in the
biological activity of the extracts provides guidance on their use as functional
food.
AB  - У овоме раду поређен је здраствени ефекaт врелих водених екстраката добијених из плодоносних тела комерцијално узгајане јестиве гљиве Agaricus bisporus (AbHW) и самоникле врсте гљиве Ganoderma resinaceum (GrHW) из региона северне Србије. Здраствени ефекат је поређен in vitro превенцијом липидне пероксидације (LPx) у модел систему линолеинске киселине, инхибицијом ангиотензин конвертујућег ензима (ACE) који има улогу у одржавању нормалног нивоа крвног притиска и јачањем способности централних холинергичких неурона инхибицијом активности ацетилхолинестеразе (AChE).
Цитотоксична активност је праћена на хуманим ћелијама тумора грлића материц (HeLa) и ћелијама хроничне мијелоидне леукемије (K562), као и на здравим мононуклеарним ћелијама периферног крвотока (PBMC). GrHW је показао већи садржај фенолних компоненти (5,9 g (100 g)-1), већу способност инхибиције LPx (EC50 = 1,07 mg mL-1),
ACE (IC50 = 0,54 mg mL-1) и AChE (IC50 = 0,37 mg mL-1); показао је већу селективност у антитуморском дејству према HeLa (IC50 = 0,14 mg mL-1) и K562 (IC50 = 0,11 mg mL-1) ћелијама. AbHW је показао већи укупни садржај протеина (6,4 g (100 g)-1), угљених хидрата (75,4 g (100 g)-1) и β-глукана (55,1 g (100 g)-1) и значајно je стимулисао пролиферацију PBMC ћелија од 152–116 % у распону концентрација од 0,046–0,187 mg mL-1. Разлика у биолошкој активности екстраката даје смернице у њиховој примени као функционалнe хранe.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Health impact of the commercially cultivated mushroom Agaricus bisporus and the wild-growing mushroom Ganoderma resinaceum – A comparative overview
T1  - Компаративни прглед здравствених ефеката комерцијално узгајане гљиве Agaricus bisporus и самоникле врсте гливе Ganoderma resinaceum
VL  - 85
IS  - 6
SP  - 721
EP  - 735
DO  - 10.2298/JSC190930129K
ER  - 

@article{
author = "Kozarski, Maja S. and Klaus, Anita and Vunduk, Jovana and Jakovljević, Dragica and Jadranin, Milka and Nikšić, Miomir",
year = "2020",
abstract = "The health promoting effects of hot water extracts obtained from
fruiting bodies of the commercially cultivated mushroom Agaricus bisporus
(AbHW) and the wild-growing mushroom Ganoderma resinaceum (GrHW)
originating from northern Serbia are presented in this research. These abilities
were compared in vitro by the prevention of lipid peroxidation (LPx) in a linoleic
acid model system, inhibition of the angiotension converting I enzyme
(ACE) that could help in the maintenance of a normal blood pressure level and
strengthening the ability of the central cholinergic neuron by inhibiting the activity
of acetylcholinesterase (AChE). Cytotoxic activities were observed
towards selected human malignant (HeLa and K562) cell lines and normal-
-human peripheral blood mononuclear cells (PBMC). GrHW contains higher
phenolics (5.9 g (100 g)-1), inhibition of LPx (EC50 = 1.07 mg mL-1), ACE
(IC50 = 0.54 mg mL-1) and AChE (IC50 = 0.37 mg mL-1), and exhibited a significant
selectivity in the antitumour action against HeLa (IC50 = 0.14 mg mL-1)
and K562 (IC50 = 0.11 mg mL-1) cells. AbHW contained higher total protein
(6.4 g (100 g)-1), carbohydrate (75.4 g (100 g)-1) and β-glucan (55.1 g (100 g)-1)
contents and induced significant proliferation of healthy PBMC from 152–116
% in the concentration range of 0.047–0.187 mg mL-1. The difference in the
biological activity of the extracts provides guidance on their use as functional
food., У овоме раду поређен је здраствени ефекaт врелих водених екстраката добијених из плодоносних тела комерцијално узгајане јестиве гљиве Agaricus bisporus (AbHW) и самоникле врсте гљиве Ganoderma resinaceum (GrHW) из региона северне Србије. Здраствени ефекат је поређен in vitro превенцијом липидне пероксидације (LPx) у модел систему линолеинске киселине, инхибицијом ангиотензин конвертујућег ензима (ACE) који има улогу у одржавању нормалног нивоа крвног притиска и јачањем способности централних холинергичких неурона инхибицијом активности ацетилхолинестеразе (AChE).
Цитотоксична активност је праћена на хуманим ћелијама тумора грлића материц (HeLa) и ћелијама хроничне мијелоидне леукемије (K562), као и на здравим мононуклеарним ћелијама периферног крвотока (PBMC). GrHW је показао већи садржај фенолних компоненти (5,9 g (100 g)-1), већу способност инхибиције LPx (EC50 = 1,07 mg mL-1),
ACE (IC50 = 0,54 mg mL-1) и AChE (IC50 = 0,37 mg mL-1); показао је већу селективност у антитуморском дејству према HeLa (IC50 = 0,14 mg mL-1) и K562 (IC50 = 0,11 mg mL-1) ћелијама. AbHW је показао већи укупни садржај протеина (6,4 g (100 g)-1), угљених хидрата (75,4 g (100 g)-1) и β-глукана (55,1 g (100 g)-1) и значајно je стимулисао пролиферацију PBMC ћелија од 152–116 % у распону концентрација од 0,046–0,187 mg mL-1. Разлика у биолошкој активности екстраката даје смернице у њиховој примени као функционалнe хранe.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Health impact of the commercially cultivated mushroom Agaricus bisporus and the wild-growing mushroom Ganoderma resinaceum – A comparative overview, Компаративни прглед здравствених ефеката комерцијално узгајане гљиве Agaricus bisporus и самоникле врсте гливе Ganoderma resinaceum",
volume = "85",
number = "6",
pages = "721-735",
doi = "10.2298/JSC190930129K"
}

Kozarski, M. S., Klaus, A., Vunduk, J., Jakovljević, D., Jadranin, M.,& Nikšić, M.. (2020). Health impact of the commercially cultivated mushroom Agaricus bisporus and the wild-growing mushroom Ganoderma resinaceum – A comparative overview. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 85(6), 721-735.
https://doi.org/10.2298/JSC190930129K

Kozarski MS, Klaus A, Vunduk J, Jakovljević D, Jadranin M, Nikšić M. Health impact of the commercially cultivated mushroom Agaricus bisporus and the wild-growing mushroom Ganoderma resinaceum – A comparative overview. in Journal of the Serbian Chemical Society. 2020;85(6):721-735.
doi:10.2298/JSC190930129K .

Kozarski, Maja S., Klaus, Anita, Vunduk, Jovana, Jakovljević, Dragica, Jadranin, Milka, Nikšić, Miomir, "Health impact of the commercially cultivated mushroom Agaricus bisporus and the wild-growing mushroom Ganoderma resinaceum – A comparative overview" in Journal of the Serbian Chemical Society, 85, no. 6 (2020):721-735,
https://doi.org/10.2298/JSC190930129K . .

TY  - CONF
AU  - Avdalović, Jelena
AU  - Ilić, Mila
AU  - Miletić, Srđan
AU  - Beškoski, Vladimir
AU  - Lugonja, Nikoleta
AU  - Milić, Jelena
AU  - Vrvić, Miroslav
PY  - 2019
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5484
AB  - Petroleum and its derivatives are among the major pollutants of soil. Bioremediation, a
method that uses the ability of microorganisms to decompose toxic waste, is a prevailing
trend in the decontamination of polluted soil contaminated by petroleum and its derivates.
Bioremediation procedures are in harmony with the principles of sustainable development, are
categorized as “environmentally friendly” technologies, do not form waste and the treated soil
can recover its natural biological activity.
The aim of this paper is to study the use of an active consortium of zymogenous
microorganisms for ex situ bioremediation of a petroleum contaminant in the soil, along with
simultaneous monitoring of the humification process.
PB  - Novi Sad : University of Novi sad, Faculty of Technology
C3  - Book of abstracts - 1st International Conference on Advance Production and Processing, 10th-11th October 2019 Novi Sad, Serbia
T1  - Investigation Of Humic Acids Evolution During Ex Situ Bioremediation Of Petroleum Contaminated Soil
SP  - 297
UR  - https://hdl.handle.net/21.15107/rcub_cer_5484
ER  - 

@conference{
author = "Avdalović, Jelena and Ilić, Mila and Miletić, Srđan and Beškoski, Vladimir and Lugonja, Nikoleta and Milić, Jelena and Vrvić, Miroslav",
year = "2019",
abstract = "Petroleum and its derivatives are among the major pollutants of soil. Bioremediation, a
method that uses the ability of microorganisms to decompose toxic waste, is a prevailing
trend in the decontamination of polluted soil contaminated by petroleum and its derivates.
Bioremediation procedures are in harmony with the principles of sustainable development, are
categorized as “environmentally friendly” technologies, do not form waste and the treated soil
can recover its natural biological activity.
The aim of this paper is to study the use of an active consortium of zymogenous
microorganisms for ex situ bioremediation of a petroleum contaminant in the soil, along with
simultaneous monitoring of the humification process.",
publisher = "Novi Sad : University of Novi sad, Faculty of Technology",
journal = "Book of abstracts - 1st International Conference on Advance Production and Processing, 10th-11th October 2019 Novi Sad, Serbia",
title = "Investigation Of Humic Acids Evolution During Ex Situ Bioremediation Of Petroleum Contaminated Soil",
pages = "297",
url = "https://hdl.handle.net/21.15107/rcub_cer_5484"
}

Avdalović, J., Ilić, M., Miletić, S., Beškoski, V., Lugonja, N., Milić, J.,& Vrvić, M.. (2019). Investigation Of Humic Acids Evolution During Ex Situ Bioremediation Of Petroleum Contaminated Soil. in Book of abstracts - 1st International Conference on Advance Production and Processing, 10th-11th October 2019 Novi Sad, Serbia
Novi Sad : University of Novi sad, Faculty of Technology., 297.
https://hdl.handle.net/21.15107/rcub_cer_5484

Avdalović J, Ilić M, Miletić S, Beškoski V, Lugonja N, Milić J, Vrvić M. Investigation Of Humic Acids Evolution During Ex Situ Bioremediation Of Petroleum Contaminated Soil. in Book of abstracts - 1st International Conference on Advance Production and Processing, 10th-11th October 2019 Novi Sad, Serbia. 2019;:297.
https://hdl.handle.net/21.15107/rcub_cer_5484 .

Avdalović, Jelena, Ilić, Mila, Miletić, Srđan, Beškoski, Vladimir, Lugonja, Nikoleta, Milić, Jelena, Vrvić, Miroslav, "Investigation Of Humic Acids Evolution During Ex Situ Bioremediation Of Petroleum Contaminated Soil" in Book of abstracts - 1st International Conference on Advance Production and Processing, 10th-11th October 2019 Novi Sad, Serbia (2019):297,
https://hdl.handle.net/21.15107/rcub_cer_5484 .

TY  - CONF
AU  - Avdalović, Jelena
AU  - Ilić, Mila
AU  - Miletić, Srđan
AU  - Žerađanin, Aleksandra
AU  - Lugonja, Nikoleta
AU  - Milić, Jelena
AU  - Vrvić, Miroslav
PY  - 2019
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5485
AB  - Groundwater is an very important natural resource. Clean groundwater is essential for the pres- 
ervation of the entire ecosystem. Bioremediation is a process which is based on the natural capacity of microorganisms to remove or transform hazardous substances from the environment into less toxic or harmless products. This paper presents the bioremediation of groundwater contaminated by petroleum hydrocarbons. The contaminated area was located at the thermal energy facility, near the city of Belgrade, on the terrace sediments of the Sava River. In the process, which lasted for 18 months, groundwater was treated by in situ bioremediation. Bioremediation treatment was conducted by a combination of biostimulation and bioaugmentation. Biostimulation was conducted by injection of nutrients. Bioaugmentation was achieved by injection of a zymogenous consortium of microorganisms, previously isolated from the contaminated groundwater, which were capable of using the contaminating substances as nutrients. The treatment was carried out in a closed bipolar system„with groundwater recirculation, by combination of extraction and injection wells. During the bioremediation, the content of petroleum hydrocarbon in groundwater decreased by 93% of the initial level. This indicates that the process of bioremediation was performed successfully.
PB  - Educons University
C3  - Proceedings - 8th International Scientific Conference on Climate Change, Economic Development, Environment and People (CCEDEP 2019), 24/10/2019, ovi Sad
T1  - Bioremediation of groundwater contaminated by petroleum hydrocarbons
SP  - 231
EP  - 238
UR  - https://hdl.handle.net/21.15107/rcub_cer_5485
ER  - 

@conference{
author = "Avdalović, Jelena and Ilić, Mila and Miletić, Srđan and Žerađanin, Aleksandra and Lugonja, Nikoleta and Milić, Jelena and Vrvić, Miroslav",
year = "2019",
abstract = "Groundwater is an very important natural resource. Clean groundwater is essential for the pres- 
ervation of the entire ecosystem. Bioremediation is a process which is based on the natural capacity of microorganisms to remove or transform hazardous substances from the environment into less toxic or harmless products. This paper presents the bioremediation of groundwater contaminated by petroleum hydrocarbons. The contaminated area was located at the thermal energy facility, near the city of Belgrade, on the terrace sediments of the Sava River. In the process, which lasted for 18 months, groundwater was treated by in situ bioremediation. Bioremediation treatment was conducted by a combination of biostimulation and bioaugmentation. Biostimulation was conducted by injection of nutrients. Bioaugmentation was achieved by injection of a zymogenous consortium of microorganisms, previously isolated from the contaminated groundwater, which were capable of using the contaminating substances as nutrients. The treatment was carried out in a closed bipolar system„with groundwater recirculation, by combination of extraction and injection wells. During the bioremediation, the content of petroleum hydrocarbon in groundwater decreased by 93% of the initial level. This indicates that the process of bioremediation was performed successfully.",
publisher = "Educons University",
journal = "Proceedings - 8th International Scientific Conference on Climate Change, Economic Development, Environment and People (CCEDEP 2019), 24/10/2019, ovi Sad",
title = "Bioremediation of groundwater contaminated by petroleum hydrocarbons",
pages = "231-238",
url = "https://hdl.handle.net/21.15107/rcub_cer_5485"
}

Avdalović, J., Ilić, M., Miletić, S., Žerađanin, A., Lugonja, N., Milić, J.,& Vrvić, M.. (2019). Bioremediation of groundwater contaminated by petroleum hydrocarbons. in Proceedings - 8th International Scientific Conference on Climate Change, Economic Development, Environment and People (CCEDEP 2019), 24/10/2019, ovi Sad
Educons University., 231-238.
https://hdl.handle.net/21.15107/rcub_cer_5485

Avdalović J, Ilić M, Miletić S, Žerađanin A, Lugonja N, Milić J, Vrvić M. Bioremediation of groundwater contaminated by petroleum hydrocarbons. in Proceedings - 8th International Scientific Conference on Climate Change, Economic Development, Environment and People (CCEDEP 2019), 24/10/2019, ovi Sad. 2019;:231-238.
https://hdl.handle.net/21.15107/rcub_cer_5485 .

Avdalović, Jelena, Ilić, Mila, Miletić, Srđan, Žerađanin, Aleksandra, Lugonja, Nikoleta, Milić, Jelena, Vrvić, Miroslav, "Bioremediation of groundwater contaminated by petroleum hydrocarbons" in Proceedings - 8th International Scientific Conference on Climate Change, Economic Development, Environment and People (CCEDEP 2019), 24/10/2019, ovi Sad (2019):231-238,
https://hdl.handle.net/21.15107/rcub_cer_5485 .

TY  - CONF
AU  - Žerađanin, Aleksandra
AU  - Joksimović, Kristina
AU  - Avdalović, Jelena
AU  - Lugonja, Nikoleta
AU  - Nakano, T.
AU  - Inui, H.
AU  - Beškoski, Vladimir
PY  - 2019
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4994
AB  - The development of chemical industry in the last century has contributed to an increase in food production, more effective disease control and improved living standards. Nevertheless, it left huge quantities of toxic substances in the environment. Persistent organic pollutants are chemicals that persist, accumulate throughout the food chain and have harmful effects on human health and the environment. Perfluoroalkyl substances such as perfluorooctane sulfonic acid, its salts and perfluorooctane sulfonyl fluoride, are on the list of persistent organic pollutants. Several recent publications have shown that microorganisms isolated from environments polluted by perfluoroalkyl substances can reduce the level of these compounds. In this paper, bacterial strain isolated from such an environment, which demonstrated capability to reduce perfluoroalkyl substances in a preliminary study, was physiologically, biochemically and molecularly characterized. The microorganism is Gram-negative, nonmotile, oxidase negative and catalase positive. The microorganism can produce a variety of hydrolase enzymes. Fatty acid methyl ester profile was also determined. Molecular characterization confirmed that the bacterium belongs to Klebsiella sp. Microorganism was successfully characterized using different methods and in the future this strain will be used in a laboratory study to analyze the mechanisms of reduction of perfluoroalkyl substance concentration.
AB  - Razvoj hemijske industrije u prošlom veku doprineo je povećanoj proizvodnji hrane, efikasnijoj kontroli bolesti i poboljšanju životnog standarda. Ipak, usled industrijskog razvoja došlo je do nagomilavanja velikih količina toksičnih supstanci u životnoj sredini. Dugotrajni organski zagađivači su hemikalije koje se zadržavaju, akumuliraju u čitavom lancu ishrane i imaju štetan uticaj na 
ljudsko zdravlje i životnu sredinu. Perfluorovana jedinjenja, kao što su perfluoroktan sulfonska kiselina, njene soli i perfluoroktan sulfonil fluorid, nalaze se na listi dugotrajnih organskih zagađivača. Nekoliko skorašnjih publikacija je pokazalo da mikroorganizmi izolovani iz životne sredine zagađene perfluorovanim jedinjenjima mogu smanjiti nivo istih. U ovom radu je bakterijski soj izolovan iz takve životne sredine fiziološki, biohemijski i molekularno okarakterisan. U preliminarnim laboratorijskim testovima soj je pokazao sposobnost smanjenja količine perfluorovanih jedinjenja. Mikroorganizam je Gram-negativan, nepokretan, oksidaza negativan i pozitivan na katalazu, proizvodi različite hidrolazne enzime. Mikroorganizmu je određen i masno-kiselinski profil. Molekularna karakterizacija je potvrdila da izolovani soj pripada rodu Klebsiella. Mikroorganizam je uspešno okarakterisan različitim metodama i ubuduće će biti korišćen u detaljnoj laboratorijskoj studiji analize mehanizama smanjenja koncentracije perfluorovanih jedinjenja.
PB  - Leskovac : Faculty of Technology
C3  - Proceedings - 13th Symposium “Nоvel Technologies and economic development”, October 18-19, 2019, Leskovac, Serbia
T1  - Biochemical and molecular characterization of Klebsiella sp. isolated from environment polluted with perfluoroalkyl substances
T1  - Biohemijska i molekularna karakterizacija Klebsiella sp. Izolovane iz životne sredine zagađene perfluorovanim jedinjenjima
SP  - 75
EP  - 82
UR  - https://hdl.handle.net/21.15107/rcub_cer_4994
ER  - 

@conference{
author = "Žerađanin, Aleksandra and Joksimović, Kristina and Avdalović, Jelena and Lugonja, Nikoleta and Nakano, T. and Inui, H. and Beškoski, Vladimir",
year = "2019",
abstract = "The development of chemical industry in the last century has contributed to an increase in food production, more effective disease control and improved living standards. Nevertheless, it left huge quantities of toxic substances in the environment. Persistent organic pollutants are chemicals that persist, accumulate throughout the food chain and have harmful effects on human health and the environment. Perfluoroalkyl substances such as perfluorooctane sulfonic acid, its salts and perfluorooctane sulfonyl fluoride, are on the list of persistent organic pollutants. Several recent publications have shown that microorganisms isolated from environments polluted by perfluoroalkyl substances can reduce the level of these compounds. In this paper, bacterial strain isolated from such an environment, which demonstrated capability to reduce perfluoroalkyl substances in a preliminary study, was physiologically, biochemically and molecularly characterized. The microorganism is Gram-negative, nonmotile, oxidase negative and catalase positive. The microorganism can produce a variety of hydrolase enzymes. Fatty acid methyl ester profile was also determined. Molecular characterization confirmed that the bacterium belongs to Klebsiella sp. Microorganism was successfully characterized using different methods and in the future this strain will be used in a laboratory study to analyze the mechanisms of reduction of perfluoroalkyl substance concentration., Razvoj hemijske industrije u prošlom veku doprineo je povećanoj proizvodnji hrane, efikasnijoj kontroli bolesti i poboljšanju životnog standarda. Ipak, usled industrijskog razvoja došlo je do nagomilavanja velikih količina toksičnih supstanci u životnoj sredini. Dugotrajni organski zagađivači su hemikalije koje se zadržavaju, akumuliraju u čitavom lancu ishrane i imaju štetan uticaj na 
ljudsko zdravlje i životnu sredinu. Perfluorovana jedinjenja, kao što su perfluoroktan sulfonska kiselina, njene soli i perfluoroktan sulfonil fluorid, nalaze se na listi dugotrajnih organskih zagađivača. Nekoliko skorašnjih publikacija je pokazalo da mikroorganizmi izolovani iz životne sredine zagađene perfluorovanim jedinjenjima mogu smanjiti nivo istih. U ovom radu je bakterijski soj izolovan iz takve životne sredine fiziološki, biohemijski i molekularno okarakterisan. U preliminarnim laboratorijskim testovima soj je pokazao sposobnost smanjenja količine perfluorovanih jedinjenja. Mikroorganizam je Gram-negativan, nepokretan, oksidaza negativan i pozitivan na katalazu, proizvodi različite hidrolazne enzime. Mikroorganizmu je određen i masno-kiselinski profil. Molekularna karakterizacija je potvrdila da izolovani soj pripada rodu Klebsiella. Mikroorganizam je uspešno okarakterisan različitim metodama i ubuduće će biti korišćen u detaljnoj laboratorijskoj studiji analize mehanizama smanjenja koncentracije perfluorovanih jedinjenja.",
publisher = "Leskovac : Faculty of Technology",
journal = "Proceedings - 13th Symposium “Nоvel Technologies and economic development”, October 18-19, 2019, Leskovac, Serbia",
title = "Biochemical and molecular characterization of Klebsiella sp. isolated from environment polluted with perfluoroalkyl substances, Biohemijska i molekularna karakterizacija Klebsiella sp. Izolovane iz životne sredine zagađene perfluorovanim jedinjenjima",
pages = "75-82",
url = "https://hdl.handle.net/21.15107/rcub_cer_4994"
}

Žerađanin, A., Joksimović, K., Avdalović, J., Lugonja, N., Nakano, T., Inui, H.,& Beškoski, V.. (2019). Biochemical and molecular characterization of Klebsiella sp. isolated from environment polluted with perfluoroalkyl substances. in Proceedings - 13th Symposium “Nоvel Technologies and economic development”, October 18-19, 2019, Leskovac, Serbia
Leskovac : Faculty of Technology., 75-82.
https://hdl.handle.net/21.15107/rcub_cer_4994

Žerađanin A, Joksimović K, Avdalović J, Lugonja N, Nakano T, Inui H, Beškoski V. Biochemical and molecular characterization of Klebsiella sp. isolated from environment polluted with perfluoroalkyl substances. in Proceedings - 13th Symposium “Nоvel Technologies and economic development”, October 18-19, 2019, Leskovac, Serbia. 2019;:75-82.
https://hdl.handle.net/21.15107/rcub_cer_4994 .

Žerađanin, Aleksandra, Joksimović, Kristina, Avdalović, Jelena, Lugonja, Nikoleta, Nakano, T., Inui, H., Beškoski, Vladimir, "Biochemical and molecular characterization of Klebsiella sp. isolated from environment polluted with perfluoroalkyl substances" in Proceedings - 13th Symposium “Nоvel Technologies and economic development”, October 18-19, 2019, Leskovac, Serbia (2019):75-82,
https://hdl.handle.net/21.15107/rcub_cer_4994 .