TY  - JOUR
AU  - Biocanin, Vladimir
AU  - Antonijevic, Djordje
AU  - Postic, Srdan
AU  - Ilic, Dragan
AU  - Vuković, Zorica
AU  - Milic, Marija
AU  - Fan, Yifang
AU  - Li, Zhiyu
AU  - Brkovic, Bozidar
AU  - Đurić, Marija
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2317
AB  - Introduction: The outcome of periapical surgery has been directly improved with the introduction of novel material formulations. The aim of the study was to compare the retrograde obturation quality of the following materials: calcium silicate (Biodentine; Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (MTA+; Cerkamed Company, Stalowa Wola, Poland), and glass ionomer cement (Fuji IX; GC Corporation, Tokyo, Japan). Methods: Materials' wettability was calculated concerning the contact angles of the cements measured using a glycerol drop. Cements' porosity was determined using mercury intrusion porosimetry and micro computed tomographic (mu CT) imaging. Extracted upper human incisors were retrofilled, and mu CT analysis was applied to calculate the volume of the gap between the retrograde filling material and root canal dentin. Experiments were performed before and after soaking the materials in simulated body fluid (SBF). Results: No statistically significant differences were found among the contact angles of the studied materials after being soaked in SBF. The material with the lowest nanoporosity (Fuji IX: 2.99% and 4.17% before and after SBF, respectively) showed the highest values of microporosity (4.2% and 3.1% before and after SBF, respectively). Biodentine had the lowest value of microporosity (1.2% and 0.8% before and after SBF, respectively) and the lowest value of microgap to the root canal wall ([10 +/- 30] x 10(-3) mm(3)). Conclusions: Biodentine and MTA possess certain advantages over Fuji IX for hermetic obturation of retrograde root canals. Biodentine shows a tendency toward the lowest marginal gap at the cement-to-dentin interface.
PB  - Elsevier Science Inc, New York
T2  - Journal of Endodontics
T1  - Marginal Gaps between 2 Calcium Silicate and Glass lonomer Cements and Apical Root Dentin
VL  - 44
IS  - 5
SP  - 816
EP  - 821
DO  - 10.1016/j.joen.2017.09.022
ER  - 

@article{
author = "Biocanin, Vladimir and Antonijevic, Djordje and Postic, Srdan and Ilic, Dragan and Vuković, Zorica and Milic, Marija and Fan, Yifang and Li, Zhiyu and Brkovic, Bozidar and Đurić, Marija",
year = "2018",
abstract = "Introduction: The outcome of periapical surgery has been directly improved with the introduction of novel material formulations. The aim of the study was to compare the retrograde obturation quality of the following materials: calcium silicate (Biodentine; Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (MTA+; Cerkamed Company, Stalowa Wola, Poland), and glass ionomer cement (Fuji IX; GC Corporation, Tokyo, Japan). Methods: Materials' wettability was calculated concerning the contact angles of the cements measured using a glycerol drop. Cements' porosity was determined using mercury intrusion porosimetry and micro computed tomographic (mu CT) imaging. Extracted upper human incisors were retrofilled, and mu CT analysis was applied to calculate the volume of the gap between the retrograde filling material and root canal dentin. Experiments were performed before and after soaking the materials in simulated body fluid (SBF). Results: No statistically significant differences were found among the contact angles of the studied materials after being soaked in SBF. The material with the lowest nanoporosity (Fuji IX: 2.99% and 4.17% before and after SBF, respectively) showed the highest values of microporosity (4.2% and 3.1% before and after SBF, respectively). Biodentine had the lowest value of microporosity (1.2% and 0.8% before and after SBF, respectively) and the lowest value of microgap to the root canal wall ([10 +/- 30] x 10(-3) mm(3)). Conclusions: Biodentine and MTA possess certain advantages over Fuji IX for hermetic obturation of retrograde root canals. Biodentine shows a tendency toward the lowest marginal gap at the cement-to-dentin interface.",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Endodontics",
title = "Marginal Gaps between 2 Calcium Silicate and Glass lonomer Cements and Apical Root Dentin",
volume = "44",
number = "5",
pages = "816-821",
doi = "10.1016/j.joen.2017.09.022"
}

Biocanin, V., Antonijevic, D., Postic, S., Ilic, D., Vuković, Z., Milic, M., Fan, Y., Li, Z., Brkovic, B.,& Đurić, M.. (2018). Marginal Gaps between 2 Calcium Silicate and Glass lonomer Cements and Apical Root Dentin. in Journal of Endodontics
Elsevier Science Inc, New York., 44(5), 816-821.
https://doi.org/10.1016/j.joen.2017.09.022

Biocanin V, Antonijevic D, Postic S, Ilic D, Vuković Z, Milic M, Fan Y, Li Z, Brkovic B, Đurić M. Marginal Gaps between 2 Calcium Silicate and Glass lonomer Cements and Apical Root Dentin. in Journal of Endodontics. 2018;44(5):816-821.
doi:10.1016/j.joen.2017.09.022 .

Biocanin, Vladimir, Antonijevic, Djordje, Postic, Srdan, Ilic, Dragan, Vuković, Zorica, Milic, Marija, Fan, Yifang, Li, Zhiyu, Brkovic, Bozidar, Đurić, Marija, "Marginal Gaps between 2 Calcium Silicate and Glass lonomer Cements and Apical Root Dentin" in Journal of Endodontics, 44, no. 5 (2018):816-821,
https://doi.org/10.1016/j.joen.2017.09.022 . .

TY  - JOUR
AU  - Milovanovic, Petar
AU  - Vuković, Zorica
AU  - Antonijevic, Djordje
AU  - Djonic, Danijela
AU  - Zivkovic, Vladimir
AU  - Nikolic, Slobodan
AU  - Djuric, Marija
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2263
AB  - Bone is a remarkable biological nanocomposite material showing peculiar hierarchical organization from smaller (nano, micro) to larger (macro) length scales. Increased material porosity is considered as the main feature of fragile bone at larger length-scales. However, there is a shortage of quantitative information on bone porosity at smaller length-scales, as well as on the distribution of pore sizes in healthy vs. fragile bone. Therefore, here we investigated how healthy and fragile bones differ in pore volume and pore size distribution patterns, considering a wide range of mostly neglected pore sizes from nano to micron-length scales (7.5 to 15000 nm). Cortical bone specimens from four young healthy women (age: 35 +/- 6 years) and five women with bone fracture (age: 82 +/- 5 years) were analyzed by mercury porosimetry. Our findings showed that, surprisingly, fragile bone demonstrated lower pore volume at the measured scales. Furtnermore, pore size distribution showed differential patterns between healthy and fragile bones, where healthy bone showed especially high proportion of pores between 200 and 15000 nm. Therefore, although fragile bones are known for increased porosity at macroscopic level and level of tens or hundreds of microns as firmly established in the literature, our study with a unique assessment range of nano-to micron-sized pores reveal that osteoporosis does not imply increased porosity at all length scales. Our thorough assessment of bone porosity reveals a specific distribution of porosities at smaller length-scales and contributes to proper understanding of bone structure which is important for designing new biomimetic bone substitute materials. [GRAPHICS]
PB  - Springer, Dordrecht
T2  - Journal of Materials Science-Materials in Medicine
T1  - Porotic paradox: distribution of cortical bone pore sizes at nano- and micro-levels in healthy vs. fragile human bone
VL  - 28
IS  - 5
DO  - 10.1007/s10856-017-5878-7
ER  - 

@article{
author = "Milovanovic, Petar and Vuković, Zorica and Antonijevic, Djordje and Djonic, Danijela and Zivkovic, Vladimir and Nikolic, Slobodan and Djuric, Marija",
year = "2017",
abstract = "Bone is a remarkable biological nanocomposite material showing peculiar hierarchical organization from smaller (nano, micro) to larger (macro) length scales. Increased material porosity is considered as the main feature of fragile bone at larger length-scales. However, there is a shortage of quantitative information on bone porosity at smaller length-scales, as well as on the distribution of pore sizes in healthy vs. fragile bone. Therefore, here we investigated how healthy and fragile bones differ in pore volume and pore size distribution patterns, considering a wide range of mostly neglected pore sizes from nano to micron-length scales (7.5 to 15000 nm). Cortical bone specimens from four young healthy women (age: 35 +/- 6 years) and five women with bone fracture (age: 82 +/- 5 years) were analyzed by mercury porosimetry. Our findings showed that, surprisingly, fragile bone demonstrated lower pore volume at the measured scales. Furtnermore, pore size distribution showed differential patterns between healthy and fragile bones, where healthy bone showed especially high proportion of pores between 200 and 15000 nm. Therefore, although fragile bones are known for increased porosity at macroscopic level and level of tens or hundreds of microns as firmly established in the literature, our study with a unique assessment range of nano-to micron-sized pores reveal that osteoporosis does not imply increased porosity at all length scales. Our thorough assessment of bone porosity reveals a specific distribution of porosities at smaller length-scales and contributes to proper understanding of bone structure which is important for designing new biomimetic bone substitute materials. [GRAPHICS]",
publisher = "Springer, Dordrecht",
journal = "Journal of Materials Science-Materials in Medicine",
title = "Porotic paradox: distribution of cortical bone pore sizes at nano- and micro-levels in healthy vs. fragile human bone",
volume = "28",
number = "5",
doi = "10.1007/s10856-017-5878-7"
}

Milovanovic, P., Vuković, Z., Antonijevic, D., Djonic, D., Zivkovic, V., Nikolic, S.,& Djuric, M.. (2017). Porotic paradox: distribution of cortical bone pore sizes at nano- and micro-levels in healthy vs. fragile human bone. in Journal of Materials Science-Materials in Medicine
Springer, Dordrecht., 28(5).
https://doi.org/10.1007/s10856-017-5878-7

Milovanovic P, Vuković Z, Antonijevic D, Djonic D, Zivkovic V, Nikolic S, Djuric M. Porotic paradox: distribution of cortical bone pore sizes at nano- and micro-levels in healthy vs. fragile human bone. in Journal of Materials Science-Materials in Medicine. 2017;28(5).
doi:10.1007/s10856-017-5878-7 .

Milovanovic, Petar, Vuković, Zorica, Antonijevic, Djordje, Djonic, Danijela, Zivkovic, Vladimir, Nikolic, Slobodan, Djuric, Marija, "Porotic paradox: distribution of cortical bone pore sizes at nano- and micro-levels in healthy vs. fragile human bone" in Journal of Materials Science-Materials in Medicine, 28, no. 5 (2017),
https://doi.org/10.1007/s10856-017-5878-7 . .

TY  - JOUR
AU  - Antonijevic, Djordje
AU  - Medigovic, Ivana
AU  - Zrilić, Milorad
AU  - Jokić, Bojan
AU  - Vuković, Zorica
AU  - Todorovic, Ljubomir
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1555
AB  - The aims of this study were to evaluate the radiopacity, compressive strength, setting time, and porosity of white Portland cement (PC) with the addition of bismuth oxide (Bi2O3), zirconium dioxide (ZrO2), and ytterbium trifluoride (YbF3) after immersion at 37 A degrees C for 7 days in distilled water or phosphate buffer saline. Specimens measuring 8 mm in diameter and 1 mm in thickness were fabricated from PC with the addition of 10, 20, and 30 wt% Bi2O3, ZrO2 or YbF3. ProRoot MTA (Dentsply, Tulsa, OK, USA) and pure PC were used as controls. For radiopacity assessments, specimens were radiographed alongside a tooth slices and an aluminum stepwedge on Extraspeed occlusal dental films (Insight Kodak, Rochester, New York). Mean optical density of each specimen was calculated and used to express radiopacity of the material as an equivalent thickness of aluminum. Compressive strength was measured by using 4-mm diameter and 6-mm high specimens and Universal testing machine. High-pressure mercury intrusion porosimeter (Carlo Erba Porosimeter 2000) was employed to measure the porosity of the specimens. The setting time was measured by using a needle of 100 g in weight. The morphology of specimens was evaluated using a scanning electron microscope (TESCAN Mira3 XMU, USA Inc.). Data were analyzed by one-way ANOVA and post hoc Tukey test (P  LT  0.05). The PC with the addition of at least 10 wt% Bi2O3 and 20 wt% ZrO2 or YbF3 demonstrated greater radiopacity value than the recommended 3 mmAl cut-off. ZrO2 and YbF3 increased the compressive strength of PC, but it was not statistically significant (P > 0.05), while Bi2O3 decreased it (P  LT  0.05). All radiopacifiers significantly increased the porosity of the experimental cements (P  LT  0.05). Bi2O3 extended the setting time of PC (P  LT  0.05), whilst ZrO2 and YbF3 did not significantly affect it (P > 0.05). ZrO2 and YbF3 may be used as a suitable alternative to replace Bi2O3 in MTA without influencing its physical properties.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - The influence of different radiopacifying agents on the radiopacity, compressive strength, setting time, and porosity of Portland cement
VL  - 18
IS  - 6
SP  - 1597
EP  - 1604
DO  - 10.1007/s00784-013-1130-0
ER  - 

@article{
author = "Antonijevic, Djordje and Medigovic, Ivana and Zrilić, Milorad and Jokić, Bojan and Vuković, Zorica and Todorovic, Ljubomir",
year = "2014",
abstract = "The aims of this study were to evaluate the radiopacity, compressive strength, setting time, and porosity of white Portland cement (PC) with the addition of bismuth oxide (Bi2O3), zirconium dioxide (ZrO2), and ytterbium trifluoride (YbF3) after immersion at 37 A degrees C for 7 days in distilled water or phosphate buffer saline. Specimens measuring 8 mm in diameter and 1 mm in thickness were fabricated from PC with the addition of 10, 20, and 30 wt% Bi2O3, ZrO2 or YbF3. ProRoot MTA (Dentsply, Tulsa, OK, USA) and pure PC were used as controls. For radiopacity assessments, specimens were radiographed alongside a tooth slices and an aluminum stepwedge on Extraspeed occlusal dental films (Insight Kodak, Rochester, New York). Mean optical density of each specimen was calculated and used to express radiopacity of the material as an equivalent thickness of aluminum. Compressive strength was measured by using 4-mm diameter and 6-mm high specimens and Universal testing machine. High-pressure mercury intrusion porosimeter (Carlo Erba Porosimeter 2000) was employed to measure the porosity of the specimens. The setting time was measured by using a needle of 100 g in weight. The morphology of specimens was evaluated using a scanning electron microscope (TESCAN Mira3 XMU, USA Inc.). Data were analyzed by one-way ANOVA and post hoc Tukey test (P  LT  0.05). The PC with the addition of at least 10 wt% Bi2O3 and 20 wt% ZrO2 or YbF3 demonstrated greater radiopacity value than the recommended 3 mmAl cut-off. ZrO2 and YbF3 increased the compressive strength of PC, but it was not statistically significant (P > 0.05), while Bi2O3 decreased it (P  LT  0.05). All radiopacifiers significantly increased the porosity of the experimental cements (P  LT  0.05). Bi2O3 extended the setting time of PC (P  LT  0.05), whilst ZrO2 and YbF3 did not significantly affect it (P > 0.05). ZrO2 and YbF3 may be used as a suitable alternative to replace Bi2O3 in MTA without influencing its physical properties.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "The influence of different radiopacifying agents on the radiopacity, compressive strength, setting time, and porosity of Portland cement",
volume = "18",
number = "6",
pages = "1597-1604",
doi = "10.1007/s00784-013-1130-0"
}

Antonijevic, D., Medigovic, I., Zrilić, M., Jokić, B., Vuković, Z.,& Todorovic, L.. (2014). The influence of different radiopacifying agents on the radiopacity, compressive strength, setting time, and porosity of Portland cement. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 18(6), 1597-1604.
https://doi.org/10.1007/s00784-013-1130-0

Antonijevic D, Medigovic I, Zrilić M, Jokić B, Vuković Z, Todorovic L. The influence of different radiopacifying agents on the radiopacity, compressive strength, setting time, and porosity of Portland cement. in Clinical Oral Investigations. 2014;18(6):1597-1604.
doi:10.1007/s00784-013-1130-0 .

Antonijevic, Djordje, Medigovic, Ivana, Zrilić, Milorad, Jokić, Bojan, Vuković, Zorica, Todorovic, Ljubomir, "The influence of different radiopacifying agents on the radiopacity, compressive strength, setting time, and porosity of Portland cement" in Clinical Oral Investigations, 18, no. 6 (2014):1597-1604,
https://doi.org/10.1007/s00784-013-1130-0 . .