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Newly Synthesized Fluorinated Cinnamylpiperazines Possessing Low In Vitro MAO-B Binding
(MDPI, 2020)
Herein, we report on the synthesis and pharmacological evaluation of ten novel fluorinated cinnamylpiperazines as potential monoamine oxidase B (MAO-B) ligands. The designed derivatives consist of either cinnamyl or ...
Effectiveness of Nature-Based Solutions in Mitigating Flood Hazard in a Mediterranean Peri-Urban Catchment
(MDPI, 2020)
Urbanization alters natural hydrological processes and enhances runoff, which affects flood hazard. Interest in nature-based solutions (NBS) for sustainable mitigation and adaptation to urban floods is growing, but the ...
Geochemical Fractionation and Risk Assessment of Potentially Toxic Elements in Sediments from Kupa River, Croatia
(MDPI, 2020)
This study investigated the quality of Kupa River sediment using sequential extraction,
ecological risk, and contamination indexes (Risk assessment code, Index of geoaccumulation,
Enrichment factor, Ecological risk factor, ...
Aminoquinolines afford resistance to cerebral malaria in susceptible mice
(Elsevier, 2020)
Objectives: Malaria treatment is impeded by increasing resistance to conventional antimalarial drugs. Here we explored the activity of ten novel benzothiophene, thiophene and benzene aminoquinolines. Methods: In vitro ...
Low-energy nanoemulsions as carriers for red raspberry seed oil: Formulation approach based on Raman spectroscopy and textural analysis, physicochemical properties, stability and in vitro antioxidant/ biological activity
(Public Library of Science (PLoS), 2020)
Considering a growing demand for medicinal/cosmetic products with natural actives, this study focuses on the low-energy nanoemulsions (LE-NEs) prepared via the Phase inversion composition (PIC) method at room temperature ...
Geochemical distribution of selected elements in flotation tailings and soils/sediments from the dam spill at the abandoned antimony mine Stolice, Serbia
(Springer Science and Business Media LLC, 2020)
Materials held within mine tailings pose a serious risk to the environment in cases of tailings dam failure. Collapse of the tailing dam at the Stolice antimony mine in West Serbia caused a spilling of tailing slurry into ...
Influence of secondary phases in A356 MMCs on their mechanical properties at macro- and nanoscale
(Springer, 2020)
Metal matrix composites are very inhomogeneous materials, and their properties depend on various parameters (production process, constituents, their interfaces, etc.). The influence of SiC microparticles (40 mu m) reinforcement ...
Synthesis and pharmacological evaluation of novel cis and trans 3‑substituted anilidopiperidines
(Springer Nature, 2020)
Background 4-Anilidopiperidine class of synthetic opioid analgesics, with it’s representative fentanyl, are by far the most potent and clinically significant for the treatment of the severe chronic and surgical pain. ...
Lead isotope ratios as tool for elucidation of chemical environment in a system of Macrolepiota procera (Scop.) Singer - soil
(Springer, 2020)
The analysis of isotope ratios of lead in the mushrooms and soil, where they were grown, assisted with a principal component analysis, offered a new perspective for understanding possible chemical environment in a real ...
Electromagnetic simulation of MXene-based plasmonic metamaterials with enhanced optical absorption
(Springer, 2020)
In this contribution we propose, design and numerically analyze a plasmonic metamaterial for enhanced optical absorption, based on 100 nm thick titanium carbide (Ti3C2Tx) MXene sheets. The analyzed metamaterial is built ...