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Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities
(Elsevier, 2007)
The antiproliferative activity of previously synthesized (Z)-cholest-4-en-6-one oxime (1), (E)-cholest-4-en-6-one oxime (2), 7-aza-B-homocholest-4-en-6-one (3) and 6-aza-B-homocholest-4-en-7-one (4) and newly synthesized ...
Estrone derived steroidal diepoxide: Biologically active compound and precursor of a stable steroidal A,B-spiro system
(Elsevier Science Inc, New York, 2009)
A simple approach to a stable steroidal estrone derived A,B-spiro system is reported. Treatment of estrone derived A-ring diepoxyalcohol with the Ac2O-TMSOTf system at the ambient temperature led to acetylation, while at ...
Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives
(Elsevier, 2007)
Starting from dehydroepiandrosterone (1) 17-picolyl (2), 17-picolinylidene (7), 17-picolinylidene-16-one (10 and 11), and 17-picolyl-16-one (15) derivatives of androst-5-ene were synthesized in one, two, four and five steps ...