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Novel strategy for encapsulation and targeted delivery of poorly water-soluble active substances
(Wiley, 2020)
Carriers for targeted delivery and controlled release of poorly water-soluble active
substances (PWSAS) are facing three challenges: (a) the encapsulation issues, (b)
limitations of PWSAS water solubility, and (c) burst ...
Modification of hydrophilic polymer network to design a carrier for a poorly water-soluble substance
(John Wiley and Sons Inc, 2020)
pH sensitive, nontoxic, and biocompatible poly(methacrylic) acid (PMAA) based soft networks have been extensively used in the design of systems for targeted drug delivery. Still, their highly hydrophilic nature limits their ...
Formulation and characterization of novel liposomes containing histidine for encapsulation of a poorly soluble vitamin
(Elsevier, 2020)
In this study, development of folic acid-loaded liposomes using a basic amino acid, histidine as a solubilizing agent for folic acid was presented, which tackled the poor solubility of this vitamin. The effect of the ...