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Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity
(Elsevier, 2018)
An increase in the copper pool in body fluids has been related to a number of pathological conditions, including infections. Copper ions may affect antibiotics via the formation of coordination bonds and/or redox reactions. ...
Novel Aminoquinoline Derivatives Significantly Reduce Parasite Load in Leishmania infantum Infected Mice
(American Chemical Society (ACS), 2018)
In this Letter, a detailed analysis of 30 4-aminoquinoline-based compounds with regard to their potential as antileishmanial drugs has been carried out. Ten compounds demonstrated IC50 LT 1 mu M against promastigote ...
A study of the structural and morphological properties of Ni-ferrite, Zn-ferrite and Ni-Zn-ferrites functionalized with starch
(Elsevier Sci Ltd, Oxford, 2018)
Zinc-ferrite, nickel-ferrite and mixed nickel-zinc ferrites were successfully synthesized via the thermal decomposition method from acetylacetonate complexes. To control the particle size and enhance dispersibility in an ...
Electrodeposited AgPd alloy coatings as efficient catalysts for the ethanol oxidation reaction
(Oxford : Pergamon-Elsevier Science Ltd, 2018)
The Pd and three AgPd alloy layers (AgPd1, AgPd2 and AgPd3) were electrodeposited onto Au disc electrodes from the solution containing high concentration of chloride ions (>12 M). All coatings were investigated by scanning ...
Identification of NQO1 and ferrochelatase as interaction partners for neuroprotective N-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-phenyl}-arylamides
(Wiley, Hoboken, 2018)
Affinity chromatography was used to identify potential cellular targets that are responsible for neuroprotective activity of N-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-phenyl}-arylamides. Active and inactive representatives ...
Modeling the hydrogen sulfide binding to heme
(Elsevier Science Inc, New York, 2018)
The binding of hydrogen sulfide to a model heme compound is investigated by coupled-cluster singles-doubles augmented by a perturbative triple excitations, CCSD(T), and density functional theory, DFT. The minimum energy ...
Differences in coating mechanism of structurally different aluminosilicates observed through the thermal analysis
(Springer, 2018)
Systematic modification of three structurally different minerals (zeolite, mica, and vermiculite) was carried out with the aim of determining the modification mechanism and exposing the hydrophobic surface that can be used ...
Biocompatible and degradable scaffolds based on 2-hydroxyethyl methacrylate, gelatin and poly(beta amino ester) crosslinkers
(Elsevier Sci Ltd, Oxford, 2018)
Gelatin hydrogels have great potential in regenerative medicine but their weak mechanical properties are a major drawback for the load-bearing applications, such as scaffolds for tissue engineering. To overcome this ...
Stacking of cyclopentadienyl organometallic sandwich and half-sandwich compounds. Strong interactions of sandwiches at large offsets
(Royal Soc Chemistry, Cambridge, 2018)
Stacking interactions of organometallic sandwich and half-sandwich compounds with cyclopentadienyl (Cp) were studied by searching and observing the crystal structures in the Cambridge Structural Database and performing ...
Novel Aminoquinoline Derivatives Significantly Reduce Parasite Load in Leishmania infantum Infected Mice
(American Chemical Society (ACS), 2018)
In this Letter, a detailed analysis of 30 4-aminoquinoline-based compounds with regard to their potential as antileishmanial drugs has been carried out. Ten compounds demonstrated IC50 LT 1 mu M against promastigote ...