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Preparation of floating polymer-valsartan delivery systems using supercritical CO2
(Springer, 2021)
This study investigates pharmaceutical polymers (Soluplus®, HPMCAS, and Eudragit® E100) and supercritical CO2-assisted process for preparation of floating valsartan delivery systems. Tested process (at pressure of 30 MPa ...
Antiproliferative activity and antioxidative potential of Swiss chard from Montenegro, grown under different irrigation and fertilization regimes
(Emerald Publishing Limited, 2021)
Purpose: The purpose of this paper is to determine the polyphenol content, antioxidative potential and antiproliferative activity of Swiss chard from Montenegro, grown under different irrigation and fertilization regimes. ...
In vitro and in vivo evaluation of fluorinated indanone derivatives as potential positron emission tomography agents for the imaging of monoamine oxidase B in the brain
(Elsevier, 2021)
Monoamine oxidases (MAOs) play a key role in the metabolism of major monoamine neurotransmitters. In particular, the upregulation of MAO-B in Parkinson's disease, Alzheimer's disease and cancer augmented the development ...
Synthesis, characterization, antimicrobial activity and DFT study of some novel Schiff bases
(Elsevier, 2021)
Two new Schiff bases derived from L-cysteine and substituted benzaldehyde were synthesized: the compound 1 [2-((2-chlorobenzylidene) amino)-3-mercaptopropanoic acid] and the compound 2 [3-mercapto-2-((2-methoxybenzylidene) ...
1,2,3,4-Tetrahydroisoquinoline Derivatives as a Novel Deoxyribonuclease I Inhibitors
(Wiley, 2021)
Herein we report an assessment of 24 1,2,3,4-tetrahydroisoquinoline derivatives for potential DNase I (deoxyribonuclease I) inhibitory properties in vitro. Four of them inhibited DNase I with IC50 values below 200 μM. The ...
The effect of natural modifiers for starch hydrophobization on performance of composite based on ethylene acrylic acid copolymer
(Wiley, 2021)
As a renewable resource, starch is considered to be fully biodegradable and nonpolluting to the environment but the hygroscopicity of starch is the main disadvantage for wider applicability in the production of a polymer-based ...
Structural and thermal properties of Sn–Ag alloys
(Elsevier, 2021)
Microstructure and thermal properties of slowly cooled Sn–10% Ag and Sn–20% Ag alloys were experimentally investigated in this study. It was found that microstructure of the studied alloys is composed of large, plate-like ...
Turbulence recognition in free convective flow by thermal - video post -processing in the case of a thermal power plant mill
(Serbia : Serbian Society of Heat Transfer Engineers, 2021)
This paper presents a study of a free convection flow around the walls of a ventilation mill of the Thermal Power Plant “Kostolac B”, Kostolac, Serbia. A combined method consists of thermography and software post-processing, ...
Recombinant Bet v 1-BanLec chimera modulates functional characteristics of peritoneal murine macrophages by promoting IL-10 secretion
(Elsevier, 2021)
Allergen-specific immunotherapy (AIT) is a desensitizing treatment for allergic diseases that corrects the underlined pathological immune response to innocuous protein antigens, called allergens. Recombinant allergens ...
3D-QSAR, molecular docking and in silico ADMET studies of propiophenone derivatives with anti-HIV-1 protease activity
(Springer Nature, 2021)
HIV protease inhibitors are one of the most important agents for the treatment of HIV infection. In this work, molecular modeling studies combining 3D-QSAR, molecular docking, MESP, HOMO, and LUMO energy calculations were ...