TY  - JOUR
AU  - Patrignani, Francesca
AU  - Prasad, Sahdeo
AU  - Novaković, Miroslav
AU  - Marin, Petar D.
AU  - Bukvicki, Danka
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4522
AB  - Lamiaceae (Labiatae) are an important group of medicinal plants, which have been used for treating heart disease in traditional medicine for centuries. These mainly aromatic plants are used as essential oils, extracts or isolated components (polyphenols, phenolic compounds, terpenes, iridoids etc.). Some Labiatae species (more than 30, such as cornmint, lavender, patchouli, rosemary etc.) are famous for their use in essential oil production worldwide. In this review, cardioprotective effects of Lamiaceae and their active secondary metabolites, as well as mechanism of action against cardiovascular diseases (hypertension, angina pectoris, hyperlipidemia, thromboembolism, coronary heart disease, heart failure, venous insufficiency, arrhythmia) will be discussed. Use of Labiatae as food or food additives (such as spices) may prevent risk of cardiovascular diseases, diabetes and cancer. This approach is also described as a part of the article. Studies on developing new, effective and safe natural products from Lamiaceae (rich source of flavonoids and other active compounds) are promising and may offer prevention and treatment for patients with coronary disease and other related diseases.
PB  - Frontiers in Bioscience - Landmark
T2  - Frontiers in Bioscience-Landmark
T1  - Lamiaceae in the treatment of cardiovascular diseases
VL  - 26
IS  - 4
SP  - 612
EP  - 643
DO  - 10.2741/4909
ER  - 

@article{
author = "Patrignani, Francesca and Prasad, Sahdeo and Novaković, Miroslav and Marin, Petar D. and Bukvicki, Danka",
year = "2021",
abstract = "Lamiaceae (Labiatae) are an important group of medicinal plants, which have been used for treating heart disease in traditional medicine for centuries. These mainly aromatic plants are used as essential oils, extracts or isolated components (polyphenols, phenolic compounds, terpenes, iridoids etc.). Some Labiatae species (more than 30, such as cornmint, lavender, patchouli, rosemary etc.) are famous for their use in essential oil production worldwide. In this review, cardioprotective effects of Lamiaceae and their active secondary metabolites, as well as mechanism of action against cardiovascular diseases (hypertension, angina pectoris, hyperlipidemia, thromboembolism, coronary heart disease, heart failure, venous insufficiency, arrhythmia) will be discussed. Use of Labiatae as food or food additives (such as spices) may prevent risk of cardiovascular diseases, diabetes and cancer. This approach is also described as a part of the article. Studies on developing new, effective and safe natural products from Lamiaceae (rich source of flavonoids and other active compounds) are promising and may offer prevention and treatment for patients with coronary disease and other related diseases.",
publisher = "Frontiers in Bioscience - Landmark",
journal = "Frontiers in Bioscience-Landmark",
title = "Lamiaceae in the treatment of cardiovascular diseases",
volume = "26",
number = "4",
pages = "612-643",
doi = "10.2741/4909"
}

Patrignani, F., Prasad, S., Novaković, M., Marin, P. D.,& Bukvicki, D.. (2021). Lamiaceae in the treatment of cardiovascular diseases. in Frontiers in Bioscience-Landmark
Frontiers in Bioscience - Landmark., 26(4), 612-643.
https://doi.org/10.2741/4909

Patrignani F, Prasad S, Novaković M, Marin PD, Bukvicki D. Lamiaceae in the treatment of cardiovascular diseases. in Frontiers in Bioscience-Landmark. 2021;26(4):612-643.
doi:10.2741/4909 .

Patrignani, Francesca, Prasad, Sahdeo, Novaković, Miroslav, Marin, Petar D., Bukvicki, Danka, "Lamiaceae in the treatment of cardiovascular diseases" in Frontiers in Bioscience-Landmark, 26, no. 4 (2021):612-643,
https://doi.org/10.2741/4909 . .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Todosijević, Marina
AU  - Đorđević, Iris
AU  - Stanković, Jovana
AU  - Mitić, Zorica S.
AU  - Tešević, Vele
AU  - Marin, Petar D.
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3620
AB  - In needle cuticular wax of Pinus halepensis, nonacosan-10-ol
is high (77.08% on average). n-Alkanes
ranged from C18 to C35 with the
most dominant C27 and C29 (32.4% and 25.8%, respectively). The carbon preference index ranged from 3.2 to 5.4 (3.4 on average),
while the average chain length ranged from 14.0 to 18.0 (17.2 on average). Long-chain
n-alkanes
strongly dominated (95.1%).
PB  - SAGE Publications Inc.
T2  - Natural Product Communications
T1  - Nonacosan-10-ol and n-Alkanes in Needles of Pinus halepensis
VL  - 15
IS  - 5
SP  - 1
EP  - 4
DO  - 10.1177/1934578X20920970
ER  - 

@article{
author = "Nikolić, Biljana and Todosijević, Marina and Đorđević, Iris and Stanković, Jovana and Mitić, Zorica S. and Tešević, Vele and Marin, Petar D.",
year = "2020",
abstract = "In needle cuticular wax of Pinus halepensis, nonacosan-10-ol
is high (77.08% on average). n-Alkanes
ranged from C18 to C35 with the
most dominant C27 and C29 (32.4% and 25.8%, respectively). The carbon preference index ranged from 3.2 to 5.4 (3.4 on average),
while the average chain length ranged from 14.0 to 18.0 (17.2 on average). Long-chain
n-alkanes
strongly dominated (95.1%).",
publisher = "SAGE Publications Inc.",
journal = "Natural Product Communications",
title = "Nonacosan-10-ol and n-Alkanes in Needles of Pinus halepensis",
volume = "15",
number = "5",
pages = "1-4",
doi = "10.1177/1934578X20920970"
}

Nikolić, B., Todosijević, M., Đorđević, I., Stanković, J., Mitić, Z. S., Tešević, V.,& Marin, P. D.. (2020). Nonacosan-10-ol and n-Alkanes in Needles of Pinus halepensis. in Natural Product Communications
SAGE Publications Inc.., 15(5), 1-4.
https://doi.org/10.1177/1934578X20920970

Nikolić B, Todosijević M, Đorđević I, Stanković J, Mitić ZS, Tešević V, Marin PD. Nonacosan-10-ol and n-Alkanes in Needles of Pinus halepensis. in Natural Product Communications. 2020;15(5):1-4.
doi:10.1177/1934578X20920970 .

Nikolić, Biljana, Todosijević, Marina, Đorđević, Iris, Stanković, Jovana, Mitić, Zorica S., Tešević, Vele, Marin, Petar D., "Nonacosan-10-ol and n-Alkanes in Needles of Pinus halepensis" in Natural Product Communications, 15, no. 5 (2020):1-4,
https://doi.org/10.1177/1934578X20920970 . .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Todosijević, Marina
AU  - Đorđević, Iris
AU  - Stanković, Jovana
AU  - Mitić, Zorica S.
AU  - Marin, Petar D.
AU  - Tešević, Vele
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3953
AB  - In leaf cuticular wax of Pinus pinaster, content of nonacosan-10-ol is high (77.1% on average). n-Alkanes ranged from C18 to C35
with the most dominant C29 (24.8%). The carbon preference index (CPItotal) ranged from 3.1 to 5.6 (4.0 on average), while the
average chain length (ACLtotal) ranged from 14.0 to 17.0 (14.8 on average). Long-chain n-alkanes (n-C25-35) strongly dominated
(80.1%) over middle-chain (n-C21-24 = 18.9%) and short-chain (n-C18-20 = 0.9%) n-alkanes.
PB  - SAGE Publications Inc.
T2  - Natural Product Communications
T1  - Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster
VL  - 15
IS  - 5
SP  - 1
EP  - 4
DO  - 10.1177/1934578X20926073
ER  - 

@article{
author = "Nikolić, Biljana and Todosijević, Marina and Đorđević, Iris and Stanković, Jovana and Mitić, Zorica S. and Marin, Petar D. and Tešević, Vele",
year = "2020",
abstract = "In leaf cuticular wax of Pinus pinaster, content of nonacosan-10-ol is high (77.1% on average). n-Alkanes ranged from C18 to C35
with the most dominant C29 (24.8%). The carbon preference index (CPItotal) ranged from 3.1 to 5.6 (4.0 on average), while the
average chain length (ACLtotal) ranged from 14.0 to 17.0 (14.8 on average). Long-chain n-alkanes (n-C25-35) strongly dominated
(80.1%) over middle-chain (n-C21-24 = 18.9%) and short-chain (n-C18-20 = 0.9%) n-alkanes.",
publisher = "SAGE Publications Inc.",
journal = "Natural Product Communications",
title = "Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster",
volume = "15",
number = "5",
pages = "1-4",
doi = "10.1177/1934578X20926073"
}

Nikolić, B., Todosijević, M., Đorđević, I., Stanković, J., Mitić, Z. S., Marin, P. D.,& Tešević, V.. (2020). Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster. in Natural Product Communications
SAGE Publications Inc.., 15(5), 1-4.
https://doi.org/10.1177/1934578X20926073

Nikolić B, Todosijević M, Đorđević I, Stanković J, Mitić ZS, Marin PD, Tešević V. Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster. in Natural Product Communications. 2020;15(5):1-4.
doi:10.1177/1934578X20926073 .

Nikolić, Biljana, Todosijević, Marina, Đorđević, Iris, Stanković, Jovana, Mitić, Zorica S., Marin, Petar D., Tešević, Vele, "Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster" in Natural Product Communications, 15, no. 5 (2020):1-4,
https://doi.org/10.1177/1934578X20926073 . .

TY  - JOUR
AU  - Zdunić, Gordana
AU  - Aradski, Ana Alimpić
AU  - Gođevac, Dejan
AU  - Živković, Jelena Č.
AU  - Laušević, Sonja Duletić
AU  - Milošević, Dijana Krstić
AU  - Šavikin, Katarina
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3446
AB  - Chokeberries (Aronia melanocarpa (Michx.) Elliot have recently become one of the most popular and widely used berry fruits, and there are numerous studies dealing with the investigation of their chemical composition and biological activities. Unlike berries, chokeberry leaves were far less investigated. Therefore, the aim of this study was to conduct a bioactivity-based analysis of chokeberry leaves collected after berries were harvested. Chemical analysis of hydroethanolic chokeberry extract and its ethyl acetate, n-butanol, and water fractions was performed. Antioxidant, hypoglycemic, and antineurodegenerative activities of the obtained samples were assessed by in vitro tests. The highest total phenolics content was found in n-butanol fraction (221.5 mg gallic acid equivalents/g dw). Fourteen compounds (six phenolic acids and eight flavonoids) were identified in the samples. Caffeoylquinic acid derivatives and quercetin glycosides were dominant phenolic compounds. The highest content of phenolic acids, as well as flavonoids, was recorded in n-butanol fraction (80.75 mg/g dw and 47.79 mg/g dw, respectively). This fraction was the most active in 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis (3-ethyl-benzothiazoline-6-sulfonic acid) (ABTS), and ferric reducing antioxidant power (FRAP) assays. Also, the n-butanol fraction was the most effective inhibitor of acetylcholinesterase (AChE) and tyrosinase (TYR) enzymes. All samples showed a better inhibitory effect on α-glucosidase enzyme with inhibition concentrations IC50 = 4.21 - 9.22 μg/mL, than α-amylase enzymes (IC50 = 14.36 - 88.61 μg/mL). Pearson’s correlation between the content of individual phenolics and the results of biological tests was performed. Thus, hyperoside and isoquercitrin showed a significant correlation with DPPH and ABTS tests, caffeoylquinic acids with FRAP test, quercetin 3-O-vicianoside with β-carotene assay, hyperoside and isoquercitrin with α-amylase inhibition activity, and isorhamnetin 3-O-rutinoside with α-glucosidase inhibition assay. Considering the obtained results, chokeberry leaves represent a valuable natural source of phenolic compounds with promising potential for the development of new products with beneficial effects on human health.
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - In vitro hypoglycemic, antioxidant and antineurodegenerative activity of chokeberry (Aronia melanocarpa) leaves
VL  - 148
SP  - 112328
DO  - 10.1016/j.indcrop.2020.112328
ER  - 

@article{
author = "Zdunić, Gordana and Aradski, Ana Alimpić and Gođevac, Dejan and Živković, Jelena Č. and Laušević, Sonja Duletić and Milošević, Dijana Krstić and Šavikin, Katarina",
year = "2020",
abstract = "Chokeberries (Aronia melanocarpa (Michx.) Elliot have recently become one of the most popular and widely used berry fruits, and there are numerous studies dealing with the investigation of their chemical composition and biological activities. Unlike berries, chokeberry leaves were far less investigated. Therefore, the aim of this study was to conduct a bioactivity-based analysis of chokeberry leaves collected after berries were harvested. Chemical analysis of hydroethanolic chokeberry extract and its ethyl acetate, n-butanol, and water fractions was performed. Antioxidant, hypoglycemic, and antineurodegenerative activities of the obtained samples were assessed by in vitro tests. The highest total phenolics content was found in n-butanol fraction (221.5 mg gallic acid equivalents/g dw). Fourteen compounds (six phenolic acids and eight flavonoids) were identified in the samples. Caffeoylquinic acid derivatives and quercetin glycosides were dominant phenolic compounds. The highest content of phenolic acids, as well as flavonoids, was recorded in n-butanol fraction (80.75 mg/g dw and 47.79 mg/g dw, respectively). This fraction was the most active in 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis (3-ethyl-benzothiazoline-6-sulfonic acid) (ABTS), and ferric reducing antioxidant power (FRAP) assays. Also, the n-butanol fraction was the most effective inhibitor of acetylcholinesterase (AChE) and tyrosinase (TYR) enzymes. All samples showed a better inhibitory effect on α-glucosidase enzyme with inhibition concentrations IC50 = 4.21 - 9.22 μg/mL, than α-amylase enzymes (IC50 = 14.36 - 88.61 μg/mL). Pearson’s correlation between the content of individual phenolics and the results of biological tests was performed. Thus, hyperoside and isoquercitrin showed a significant correlation with DPPH and ABTS tests, caffeoylquinic acids with FRAP test, quercetin 3-O-vicianoside with β-carotene assay, hyperoside and isoquercitrin with α-amylase inhibition activity, and isorhamnetin 3-O-rutinoside with α-glucosidase inhibition assay. Considering the obtained results, chokeberry leaves represent a valuable natural source of phenolic compounds with promising potential for the development of new products with beneficial effects on human health.",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "In vitro hypoglycemic, antioxidant and antineurodegenerative activity of chokeberry (Aronia melanocarpa) leaves",
volume = "148",
pages = "112328",
doi = "10.1016/j.indcrop.2020.112328"
}

Zdunić, G., Aradski, A. A., Gođevac, D., Živković, J. Č., Laušević, S. D., Milošević, D. K.,& Šavikin, K.. (2020). In vitro hypoglycemic, antioxidant and antineurodegenerative activity of chokeberry (Aronia melanocarpa) leaves. in Industrial Crops and Products
Elsevier., 148, 112328.
https://doi.org/10.1016/j.indcrop.2020.112328

Zdunić G, Aradski AA, Gođevac D, Živković JČ, Laušević SD, Milošević DK, Šavikin K. In vitro hypoglycemic, antioxidant and antineurodegenerative activity of chokeberry (Aronia melanocarpa) leaves. in Industrial Crops and Products. 2020;148:112328.
doi:10.1016/j.indcrop.2020.112328 .

Zdunić, Gordana, Aradski, Ana Alimpić, Gođevac, Dejan, Živković, Jelena Č., Laušević, Sonja Duletić, Milošević, Dijana Krstić, Šavikin, Katarina, "In vitro hypoglycemic, antioxidant and antineurodegenerative activity of chokeberry (Aronia melanocarpa) leaves" in Industrial Crops and Products, 148 (2020):112328,
https://doi.org/10.1016/j.indcrop.2020.112328 . .

TY  - JOUR
AU  - Novaković, Miroslav
AU  - Bukvicki, Danka
AU  - Anđelković, Boban D.
AU  - Ilić-Tomić, Tatjana
AU  - Veljić, Milan
AU  - Tešević, Vele
AU  - Asakawa, Yoshinori
PY  - 2019
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2838
AB  - Seven new bisbibenzyls (1−7) were isolated from the methanol extract of the liverwort Lunularia cruciata along with one previously known bibenzyl and five known bisbibenzyls. The structures of compounds 1−7 were elucidated on the basis of the spectroscopic data. These newly isolated bisbibenzyls may be divided into two groups, the acyclic bisbibenzyls, perrottetins (1− 3), and the cyclic analogues, riccardins (4−7). Besides standard perrottetin and riccardin structures (1 and 4, respectively), they contain phenanthrene (3 and 5), dihydrophenanthrene (2), and quinone moieties (6 and 7), rarely found in natural products. The new compounds 3 and 5, as well as the known riccardin G, exhibited cytotoxic activity against the A549 lung cancer cell line with IC50 values of 5.0, 5.0, and 2.5 μM, respectively.
PB  - American Chemical Society (ACS)
T2  - Journal of Natural Products
T1  - Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata
VL  - 82
IS  - 4
SP  - 694
EP  - 701
DO  - 10.1021/acs.jnatprod.8b00390
ER  - 

@article{
author = "Novaković, Miroslav and Bukvicki, Danka and Anđelković, Boban D. and Ilić-Tomić, Tatjana and Veljić, Milan and Tešević, Vele and Asakawa, Yoshinori",
year = "2019",
abstract = "Seven new bisbibenzyls (1−7) were isolated from the methanol extract of the liverwort Lunularia cruciata along with one previously known bibenzyl and five known bisbibenzyls. The structures of compounds 1−7 were elucidated on the basis of the spectroscopic data. These newly isolated bisbibenzyls may be divided into two groups, the acyclic bisbibenzyls, perrottetins (1− 3), and the cyclic analogues, riccardins (4−7). Besides standard perrottetin and riccardin structures (1 and 4, respectively), they contain phenanthrene (3 and 5), dihydrophenanthrene (2), and quinone moieties (6 and 7), rarely found in natural products. The new compounds 3 and 5, as well as the known riccardin G, exhibited cytotoxic activity against the A549 lung cancer cell line with IC50 values of 5.0, 5.0, and 2.5 μM, respectively.",
publisher = "American Chemical Society (ACS)",
journal = "Journal of Natural Products",
title = "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata",
volume = "82",
number = "4",
pages = "694-701",
doi = "10.1021/acs.jnatprod.8b00390"
}

Novaković, M., Bukvicki, D., Anđelković, B. D., Ilić-Tomić, T., Veljić, M., Tešević, V.,& Asakawa, Y.. (2019). Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata. in Journal of Natural Products
American Chemical Society (ACS)., 82(4), 694-701.
https://doi.org/10.1021/acs.jnatprod.8b00390

Novaković M, Bukvicki D, Anđelković BD, Ilić-Tomić T, Veljić M, Tešević V, Asakawa Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata. in Journal of Natural Products. 2019;82(4):694-701.
doi:10.1021/acs.jnatprod.8b00390 .

Novaković, Miroslav, Bukvicki, Danka, Anđelković, Boban D., Ilić-Tomić, Tatjana, Veljić, Milan, Tešević, Vele, Asakawa, Yoshinori, "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata" in Journal of Natural Products, 82, no. 4 (2019):694-701,
https://doi.org/10.1021/acs.jnatprod.8b00390 . .

TY  - DATA
AU  - Novaković, Miroslav
AU  - Bukvicki, Danka
AU  - Anđelković, Boban D.
AU  - Ilić-Tomić, Tatjana
AU  - Veljić, Milan
AU  - Tešević, Vele
AU  - Asakawa, Yoshinori
PY  - 2019
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4449
AB  - NMR spectra of the isolated compounds and additional figures and tables. Table S1. Elution Program for the Silica Gel Column Separation;  Figure S1. Aromatic part of the 1H NMR spectrum of compound 1;
PB  - American Chemical Society (ACS)
T2  - Journal of Natural Products
T1  - Supporting information for: "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata"
DO  - 10.1021/acs.jnatprod.8b00390.s001
ER  - 

@misc{
author = "Novaković, Miroslav and Bukvicki, Danka and Anđelković, Boban D. and Ilić-Tomić, Tatjana and Veljić, Milan and Tešević, Vele and Asakawa, Yoshinori",
year = "2019",
abstract = "NMR spectra of the isolated compounds and additional figures and tables. Table S1. Elution Program for the Silica Gel Column Separation;  Figure S1. Aromatic part of the 1H NMR spectrum of compound 1;",
publisher = "American Chemical Society (ACS)",
journal = "Journal of Natural Products",
title = "Supporting information for: "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata"",
doi = "10.1021/acs.jnatprod.8b00390.s001"
}

Novaković, M., Bukvicki, D., Anđelković, B. D., Ilić-Tomić, T., Veljić, M., Tešević, V.,& Asakawa, Y.. (2019). Supporting information for: "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata". in Journal of Natural Products
American Chemical Society (ACS)..
https://doi.org/10.1021/acs.jnatprod.8b00390.s001

Novaković M, Bukvicki D, Anđelković BD, Ilić-Tomić T, Veljić M, Tešević V, Asakawa Y. Supporting information for: "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata". in Journal of Natural Products. 2019;.
doi:10.1021/acs.jnatprod.8b00390.s001 .

Novaković, Miroslav, Bukvicki, Danka, Anđelković, Boban D., Ilić-Tomić, Tatjana, Veljić, Milan, Tešević, Vele, Asakawa, Yoshinori, "Supporting information for: "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata"" in Journal of Natural Products (2019),
https://doi.org/10.1021/acs.jnatprod.8b00390.s001 . .

TY  - DATA
AU  - Novaković, Miroslav
AU  - Bukvicki, Danka
AU  - Vajs, Vlatka
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan
AU  - Marin, Petar D.
AU  - Asakawa, Yoshinori
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4448
AB  - Text S1. General experimental procedures Table S1. Elution system for the silica gel column chromatography separation of biotransformed products Figure 1S. 1 H NMR spectrum of compound 5 Figure 2S. 13C NMR spectrum of compound 5 Figure 3S. 1 H NMR spectrum of compound 6 Figure 4S. 13C NMR spectrum of compound 6 Figure 5S. 1 H NMR spectrum of compound 7 Figure 6S. Aromatic part of the 1 H NMR spectrum of compound 7 Figure 7S. 13C NMR spectrum of compound 7
PB  - SAGE Publications
T2  - Natural Product Communications
T1  - Supplementary material for: "Microbial Transformation of Calamintha glandulosa Essential Oil by Aspergillus niger"
UR  - https://hdl.handle.net/21.15107/rcub_cer_4448
ER  - 

@misc{
author = "Novaković, Miroslav and Bukvicki, Danka and Vajs, Vlatka and Tešević, Vele and Milosavljević, Slobodan and Marin, Petar D. and Asakawa, Yoshinori",
year = "2018",
abstract = "Text S1. General experimental procedures Table S1. Elution system for the silica gel column chromatography separation of biotransformed products Figure 1S. 1 H NMR spectrum of compound 5 Figure 2S. 13C NMR spectrum of compound 5 Figure 3S. 1 H NMR spectrum of compound 6 Figure 4S. 13C NMR spectrum of compound 6 Figure 5S. 1 H NMR spectrum of compound 7 Figure 6S. Aromatic part of the 1 H NMR spectrum of compound 7 Figure 7S. 13C NMR spectrum of compound 7",
publisher = "SAGE Publications",
journal = "Natural Product Communications",
title = "Supplementary material for: "Microbial Transformation of Calamintha glandulosa Essential Oil by Aspergillus niger"",
url = "https://hdl.handle.net/21.15107/rcub_cer_4448"
}

Novaković, M., Bukvicki, D., Vajs, V., Tešević, V., Milosavljević, S., Marin, P. D.,& Asakawa, Y.. (2018). Supplementary material for: "Microbial Transformation of Calamintha glandulosa Essential Oil by Aspergillus niger". in Natural Product Communications
SAGE Publications..
https://hdl.handle.net/21.15107/rcub_cer_4448

Novaković M, Bukvicki D, Vajs V, Tešević V, Milosavljević S, Marin PD, Asakawa Y. Supplementary material for: "Microbial Transformation of Calamintha glandulosa Essential Oil by Aspergillus niger". in Natural Product Communications. 2018;.
https://hdl.handle.net/21.15107/rcub_cer_4448 .

Novaković, Miroslav, Bukvicki, Danka, Vajs, Vlatka, Tešević, Vele, Milosavljević, Slobodan, Marin, Petar D., Asakawa, Yoshinori, "Supplementary material for: "Microbial Transformation of Calamintha glandulosa Essential Oil by Aspergillus niger"" in Natural Product Communications (2018),
https://hdl.handle.net/21.15107/rcub_cer_4448 .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Matovic, Milie
AU  - Todosijević, Marina
AU  - Stanković, Jovana
AU  - Cvetković, Mirjana
AU  - Marin, Petar D.
AU  - Tešević, Vele
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2439
AB  - Terpene compounds of Tanacetum macrophyllum as 1) essential oils, obtained by hydrodistillation (HD), 2) essential oil extracts, obtained by simultaneous' hydrodistillation and extraction (SDE) and 3) volatiles, obtained by Static Headspace GC-MS analysis (HS) were processed. Monoterpenes were the most dominant (49.2%, 49.5% and 90.4%, respectively). Profiles of essential oils obtained by HD and SD were quite similar, with oxygenated monoterpenes (39.3% and 39.4%) being the most abundant. In HS volatiles oxygenated monoterpenes also dominated (57.4%). Total sesquiterpenes were abundant in HD and SDE volatiles (38.2% and 39.2%, resp.), where sesquiterpene hydrocarbons were prevalent (27.3% and 28.7%, resp.). Germacrene D was dominant in HD and SDE oils (22.0% and 23.3%, resp.) and 1,8-cineole in HS volatiles (34.3%). To our knowledge, this is the first use of Headspace technique on T macrophyllum. Furthermore, this is the first comparison of different techniques of volatile extraction in T. macrophyllum.
PB  - Natural Products Inc, Westerville
T2  - Natural Product Communications
T1  - Volatiles of Tanacetum macrophyllum Obtained by Different Extraction Methods
VL  - 13
IS  - 7
SP  - 891
EP  - 893
UR  - https://hdl.handle.net/21.15107/rcub_cer_2439
ER  - 

@article{
author = "Nikolić, Biljana and Matovic, Milie and Todosijević, Marina and Stanković, Jovana and Cvetković, Mirjana and Marin, Petar D. and Tešević, Vele",
year = "2018",
abstract = "Terpene compounds of Tanacetum macrophyllum as 1) essential oils, obtained by hydrodistillation (HD), 2) essential oil extracts, obtained by simultaneous' hydrodistillation and extraction (SDE) and 3) volatiles, obtained by Static Headspace GC-MS analysis (HS) were processed. Monoterpenes were the most dominant (49.2%, 49.5% and 90.4%, respectively). Profiles of essential oils obtained by HD and SD were quite similar, with oxygenated monoterpenes (39.3% and 39.4%) being the most abundant. In HS volatiles oxygenated monoterpenes also dominated (57.4%). Total sesquiterpenes were abundant in HD and SDE volatiles (38.2% and 39.2%, resp.), where sesquiterpene hydrocarbons were prevalent (27.3% and 28.7%, resp.). Germacrene D was dominant in HD and SDE oils (22.0% and 23.3%, resp.) and 1,8-cineole in HS volatiles (34.3%). To our knowledge, this is the first use of Headspace technique on T macrophyllum. Furthermore, this is the first comparison of different techniques of volatile extraction in T. macrophyllum.",
publisher = "Natural Products Inc, Westerville",
journal = "Natural Product Communications",
title = "Volatiles of Tanacetum macrophyllum Obtained by Different Extraction Methods",
volume = "13",
number = "7",
pages = "891-893",
url = "https://hdl.handle.net/21.15107/rcub_cer_2439"
}

Nikolić, B., Matovic, M., Todosijević, M., Stanković, J., Cvetković, M., Marin, P. D.,& Tešević, V.. (2018). Volatiles of Tanacetum macrophyllum Obtained by Different Extraction Methods. in Natural Product Communications
Natural Products Inc, Westerville., 13(7), 891-893.
https://hdl.handle.net/21.15107/rcub_cer_2439

Nikolić B, Matovic M, Todosijević M, Stanković J, Cvetković M, Marin PD, Tešević V. Volatiles of Tanacetum macrophyllum Obtained by Different Extraction Methods. in Natural Product Communications. 2018;13(7):891-893.
https://hdl.handle.net/21.15107/rcub_cer_2439 .

Nikolić, Biljana, Matovic, Milie, Todosijević, Marina, Stanković, Jovana, Cvetković, Mirjana, Marin, Petar D., Tešević, Vele, "Volatiles of Tanacetum macrophyllum Obtained by Different Extraction Methods" in Natural Product Communications, 13, no. 7 (2018):891-893,
https://hdl.handle.net/21.15107/rcub_cer_2439 .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Todosijević, Marina
AU  - Ratknic, Mihajlo
AU  - Đorđević, Iris
AU  - Stanković, Jovana
AU  - Cvetković, Mirjana
AU  - Marin, Petar D.
AU  - Tešević, Vele
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2483
AB  - Simultaneous hydrodistillation and extraction of Pinus cembra needles from Slovakia was done (via Likens Nickerson apparatus) for the first time. In essential oil extracts 55 compounds were identified, comprising 99.6% of the extract. The most abundant were monoterpene hydrocarbons (71.0%). In the terpene profile alpha-pinene, limonene/beta-phellandrene, germacrene D, beta-pinene, and delta-cadinene dominated (53.2%, 11.4%, 9.4%, 4.6%, and 4.3%, respectively). Seven new compounds for P. cembra, such as methyl daniellate (0.5%), 1,8 cineole (0.2%) and trans-cadina-1(6),4-diene (0.2%), etc. were found. In needle cuticular wax of P. cembra the amount of nonacosan-10-ol was 75.8%. n-Alkanes ranged from C-20 to C-35 with the most dominant C-31, C-29 and C-33 (33.4%, 16.9%, and 9.6%, resp.). Differences in terpene profiles between Slovakian and Greece from one side and Romanian and Polish cembran pines on the other side could be the consequence of its disjuncted areal in Carpathian Mountains caused by glaciation and survival of species in different ecological niches. Obtained differences in n-alkane profiles among our and literature results could be the consequence of different age of trees.
PB  - Natural Products Inc, Westerville
T2  - Natural Product Communications
T1  - Terpenes and n-Alkanes in Needles of Pinus cembra
VL  - 13
IS  - 8
SP  - 1035
EP  - 1037
UR  - https://hdl.handle.net/21.15107/rcub_cer_2483
ER  - 

@article{
author = "Nikolić, Biljana and Todosijević, Marina and Ratknic, Mihajlo and Đorđević, Iris and Stanković, Jovana and Cvetković, Mirjana and Marin, Petar D. and Tešević, Vele",
year = "2018",
abstract = "Simultaneous hydrodistillation and extraction of Pinus cembra needles from Slovakia was done (via Likens Nickerson apparatus) for the first time. In essential oil extracts 55 compounds were identified, comprising 99.6% of the extract. The most abundant were monoterpene hydrocarbons (71.0%). In the terpene profile alpha-pinene, limonene/beta-phellandrene, germacrene D, beta-pinene, and delta-cadinene dominated (53.2%, 11.4%, 9.4%, 4.6%, and 4.3%, respectively). Seven new compounds for P. cembra, such as methyl daniellate (0.5%), 1,8 cineole (0.2%) and trans-cadina-1(6),4-diene (0.2%), etc. were found. In needle cuticular wax of P. cembra the amount of nonacosan-10-ol was 75.8%. n-Alkanes ranged from C-20 to C-35 with the most dominant C-31, C-29 and C-33 (33.4%, 16.9%, and 9.6%, resp.). Differences in terpene profiles between Slovakian and Greece from one side and Romanian and Polish cembran pines on the other side could be the consequence of its disjuncted areal in Carpathian Mountains caused by glaciation and survival of species in different ecological niches. Obtained differences in n-alkane profiles among our and literature results could be the consequence of different age of trees.",
publisher = "Natural Products Inc, Westerville",
journal = "Natural Product Communications",
title = "Terpenes and n-Alkanes in Needles of Pinus cembra",
volume = "13",
number = "8",
pages = "1035-1037",
url = "https://hdl.handle.net/21.15107/rcub_cer_2483"
}

Nikolić, B., Todosijević, M., Ratknic, M., Đorđević, I., Stanković, J., Cvetković, M., Marin, P. D.,& Tešević, V.. (2018). Terpenes and n-Alkanes in Needles of Pinus cembra. in Natural Product Communications
Natural Products Inc, Westerville., 13(8), 1035-1037.
https://hdl.handle.net/21.15107/rcub_cer_2483

Nikolić B, Todosijević M, Ratknic M, Đorđević I, Stanković J, Cvetković M, Marin PD, Tešević V. Terpenes and n-Alkanes in Needles of Pinus cembra. in Natural Product Communications. 2018;13(8):1035-1037.
https://hdl.handle.net/21.15107/rcub_cer_2483 .

Nikolić, Biljana, Todosijević, Marina, Ratknic, Mihajlo, Đorđević, Iris, Stanković, Jovana, Cvetković, Mirjana, Marin, Petar D., Tešević, Vele, "Terpenes and n-Alkanes in Needles of Pinus cembra" in Natural Product Communications, 13, no. 8 (2018):1035-1037,
https://hdl.handle.net/21.15107/rcub_cer_2483 .

TY  - JOUR
AU  - Bukvicki, Danka
AU  - Novaković, Miroslav
AU  - Ab, Ghani Nurunajah
AU  - Marin, Petar D.
AU  - Asakawa, Yoshinori
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2438
AB  - This manuscript describes the first detailed chemical investigation of endemic species Iris adriatica, including isolation and structure elucidation. Chemical analyses of the rhizome CH2Cl2/MeOH (2:1) extract revealed fourteen secondary metabolites, mainly isoflavonoids. Among isoflavonoids, two groups have been found: nigricin-type and tectorigenin-type. Dominant group of the isolated compounds has been nigricin-type isoflavones: nigricin, nigricin-4'-(1-O-beta-D- glucopyranoside) and nigricin-4'-(1-O-beta-D-glucopyranosyl (1-6)-beta-D-glucopyranoside) with 2.5, 10 and 1% of the total extract, respectively. Irisxanthone - xanthone C-glucoside, beta-sitosterol, benzophenone and one of its derivatives have also been found. Nigricin-type isoflavonoids and irisxanthone can be considered as possible chemotaxonomic markers for I. adriatica. 5,3',5'-Trimethoxy-6,7-methylenedioxyisoflavone-4'-(1-O-beta-D-glucopyranoside) and benzophenone have been isolated from Iris species for the first time. Left-hand image of Iris adriatica (Adriatic potato) with redditsh purple flowers
PB  - Taylor and Francis Ltd.
T2  - Natural Product Research
T1  - Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)
VL  - 32
IS  - 15
SP  - 1849
EP  - 1852
DO  - 10.1080/14786419.2017.1402309
ER  - 

@article{
author = "Bukvicki, Danka and Novaković, Miroslav and Ab, Ghani Nurunajah and Marin, Petar D. and Asakawa, Yoshinori",
year = "2018",
abstract = "This manuscript describes the first detailed chemical investigation of endemic species Iris adriatica, including isolation and structure elucidation. Chemical analyses of the rhizome CH2Cl2/MeOH (2:1) extract revealed fourteen secondary metabolites, mainly isoflavonoids. Among isoflavonoids, two groups have been found: nigricin-type and tectorigenin-type. Dominant group of the isolated compounds has been nigricin-type isoflavones: nigricin, nigricin-4'-(1-O-beta-D- glucopyranoside) and nigricin-4'-(1-O-beta-D-glucopyranosyl (1-6)-beta-D-glucopyranoside) with 2.5, 10 and 1% of the total extract, respectively. Irisxanthone - xanthone C-glucoside, beta-sitosterol, benzophenone and one of its derivatives have also been found. Nigricin-type isoflavonoids and irisxanthone can be considered as possible chemotaxonomic markers for I. adriatica. 5,3',5'-Trimethoxy-6,7-methylenedioxyisoflavone-4'-(1-O-beta-D-glucopyranoside) and benzophenone have been isolated from Iris species for the first time. Left-hand image of Iris adriatica (Adriatic potato) with redditsh purple flowers",
publisher = "Taylor and Francis Ltd.",
journal = "Natural Product Research",
title = "Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)",
volume = "32",
number = "15",
pages = "1849-1852",
doi = "10.1080/14786419.2017.1402309"
}

Bukvicki, D., Novaković, M., Ab, G. N., Marin, P. D.,& Asakawa, Y.. (2018). Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae). in Natural Product Research
Taylor and Francis Ltd.., 32(15), 1849-1852.
https://doi.org/10.1080/14786419.2017.1402309

Bukvicki D, Novaković M, Ab GN, Marin PD, Asakawa Y. Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae). in Natural Product Research. 2018;32(15):1849-1852.
doi:10.1080/14786419.2017.1402309 .

Bukvicki, Danka, Novaković, Miroslav, Ab, Ghani Nurunajah, Marin, Petar D., Asakawa, Yoshinori, "Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)" in Natural Product Research, 32, no. 15 (2018):1849-1852,
https://doi.org/10.1080/14786419.2017.1402309 . .

TY  - DATA
AU  - Bukvicki, Danka
AU  - Novaković, Miroslav
AU  - Ab, Ghani Nurunajah
AU  - Marin, Petar D.
AU  - Asakawa, Yoshinori
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4469
AB  - Experimental data: Plant material; Extract preparation; Extract separation; General. Table S1. Silica gel column separation program. Isolation. Figure S1. The main HMBC correlations in both types of Iris adriatica isofavonoids; A - nigricin-type, B - tectorigenin-type. 1H and 13C NMR spectra of all isolated compounds.
PB  - Taylor and Francis
T2  - Natural Product Research
T1  - Supplementary material for: "Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)"
DO  - 10.6084/m9.figshare.5592772.v1
ER  - 

@misc{
author = "Bukvicki, Danka and Novaković, Miroslav and Ab, Ghani Nurunajah and Marin, Petar D. and Asakawa, Yoshinori",
year = "2018",
abstract = "Experimental data: Plant material; Extract preparation; Extract separation; General. Table S1. Silica gel column separation program. Isolation. Figure S1. The main HMBC correlations in both types of Iris adriatica isofavonoids; A - nigricin-type, B - tectorigenin-type. 1H and 13C NMR spectra of all isolated compounds.",
publisher = "Taylor and Francis",
journal = "Natural Product Research",
title = "Supplementary material for: "Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)"",
doi = "10.6084/m9.figshare.5592772.v1"
}

Bukvicki, D., Novaković, M., Ab, G. N., Marin, P. D.,& Asakawa, Y.. (2018). Supplementary material for: "Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)". in Natural Product Research
Taylor and Francis..
https://doi.org/10.6084/m9.figshare.5592772.v1

Bukvicki D, Novaković M, Ab GN, Marin PD, Asakawa Y. Supplementary material for: "Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)". in Natural Product Research. 2018;.
doi:10.6084/m9.figshare.5592772.v1 .

Bukvicki, Danka, Novaković, Miroslav, Ab, Ghani Nurunajah, Marin, Petar D., Asakawa, Yoshinori, "Supplementary material for: "Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)"" in Natural Product Research (2018),
https://doi.org/10.6084/m9.figshare.5592772.v1 . .

TY  - JOUR
AU  - Novaković, Miroslav
AU  - Bukvicki, Danka
AU  - Vajs, Vlatka
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan
AU  - Marin, Petar D.
AU  - Asakawa, Yoshinori
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2294
AB  - A number of potentially useful compounds with various biological activities can be obtained from plant metabolites by microorganisms. In present research, essential oil of Calamintha glandulosa was subjected to the biotransformation process by mycromicete Aspergillus niger. GC/MS analyses of the original and biotransformed essential oil have revealed six(1-6) biotransformed compounds from one of the main component-limonene and one biotransformed product (7) originating from the less abundant component-thymol. Piperitone epoxide and piperitenone epoxide, the most abundant components of the original oil, were not biotransformed but gave three artefacts (A1, A2, B1) due to the acidic conditions formed in A. niger medium. Compounds 5, 6 as well as 7 have not been previously found as a biotransformation products of limonene (5 and 6) and thymol (7), respectively. New products (5, 6, and 7) together with the artefacts, were isolated by silica gel column chromatography followed by preparative silica gel thin layer chromatography, and their structures were established by a combination of 1D and 2D NMR spectra and GC/MS data. Biotransformation has one more confirmed as useful method, complementary to synthesis, for obtaining different type of molecules.
PB  - SAGE Publications
T2  - Natural Product Communications
T1  - Microbial Transformation of Calamintha glandulosa Essential Oil by Aspergillus niger
VL  - 13
IS  - 4
SP  - 479
EP  - 482
DO  - 10.1177/1934578x1801300425
ER  - 

@article{
author = "Novaković, Miroslav and Bukvicki, Danka and Vajs, Vlatka and Tešević, Vele and Milosavljević, Slobodan and Marin, Petar D. and Asakawa, Yoshinori",
year = "2018",
abstract = "A number of potentially useful compounds with various biological activities can be obtained from plant metabolites by microorganisms. In present research, essential oil of Calamintha glandulosa was subjected to the biotransformation process by mycromicete Aspergillus niger. GC/MS analyses of the original and biotransformed essential oil have revealed six(1-6) biotransformed compounds from one of the main component-limonene and one biotransformed product (7) originating from the less abundant component-thymol. Piperitone epoxide and piperitenone epoxide, the most abundant components of the original oil, were not biotransformed but gave three artefacts (A1, A2, B1) due to the acidic conditions formed in A. niger medium. Compounds 5, 6 as well as 7 have not been previously found as a biotransformation products of limonene (5 and 6) and thymol (7), respectively. New products (5, 6, and 7) together with the artefacts, were isolated by silica gel column chromatography followed by preparative silica gel thin layer chromatography, and their structures were established by a combination of 1D and 2D NMR spectra and GC/MS data. Biotransformation has one more confirmed as useful method, complementary to synthesis, for obtaining different type of molecules.",
publisher = "SAGE Publications",
journal = "Natural Product Communications",
title = "Microbial Transformation of Calamintha glandulosa Essential Oil by Aspergillus niger",
volume = "13",
number = "4",
pages = "479-482",
doi = "10.1177/1934578x1801300425"
}

Novaković, M., Bukvicki, D., Vajs, V., Tešević, V., Milosavljević, S., Marin, P. D.,& Asakawa, Y.. (2018). Microbial Transformation of Calamintha glandulosa Essential Oil by Aspergillus niger. in Natural Product Communications
SAGE Publications., 13(4), 479-482.
https://doi.org/10.1177/1934578x1801300425

Novaković M, Bukvicki D, Vajs V, Tešević V, Milosavljević S, Marin PD, Asakawa Y. Microbial Transformation of Calamintha glandulosa Essential Oil by Aspergillus niger. in Natural Product Communications. 2018;13(4):479-482.
doi:10.1177/1934578x1801300425 .

Novaković, Miroslav, Bukvicki, Danka, Vajs, Vlatka, Tešević, Vele, Milosavljević, Slobodan, Marin, Petar D., Asakawa, Yoshinori, "Microbial Transformation of Calamintha glandulosa Essential Oil by Aspergillus niger" in Natural Product Communications, 13, no. 4 (2018):479-482,
https://doi.org/10.1177/1934578x1801300425 . .

TY  - JOUR
AU  - Mileski, Ksenija S.
AU  - Trifunović, Snežana
AU  - Ciric, Ana D.
AU  - Sakic, Zeljana M.
AU  - Ristic, Mihailo S.
AU  - Todorović, Nina
AU  - Matevski, Vlado S.
AU  - Marin, Petar D.
AU  - Tešević, Vele
AU  - Dzamic, Ana M.
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2936
AB  - The essential oil, different extracts, and isolated compounds of Angelica pancicii Vandas (Apiaceae) were investigated for the first time. The GC-FID and GC-MS analyses revealed sesquiterpenoids as the main constituents of A. pancicii essential oil of aerial parts with bornyl acetate (8.08%), n-octanol (5.82%), kessane (4.26%), and beta-selinene (4.26%) as the main constituents. Analysis of methanol extracts, using an HPLC-DAD/ESI-ToF-MS system, showed a total of 52 compounds in the aerial parts and 53 in the roots, indicating coumarins as the main constituents. In addition, new chromone (1) and six known furanocoumarins (2-7) were isolated from the roots and structurally elucidated by combined spectroscopic methods. The aerial part extracts exhibited higher polyphenolic contents and antioxidant activity evaluated by three radical scavenging assays. Using a microwell dilution method, the strongest antibacterial activity profiles were determined for ethanol and methanol root extracts (minimum bactericidal concentrations (MBCs) = 0.25-3.00 mg/mL), which were comparable to the activity of streptomycin (MBCs = 0.34-1.24 mg/mL), while the strongest antibacterial compound of A. pancicii was oxypeucedanin hydrate (MBCs = 0.50-8.00 mg/mL). Antifungal potential was in moderate extent, and the highest activity was obtained for root methanol extract (minimum fungicidal concentrations (MFCs) = 4.00-14.00 mg/mL). Tested sub-minimum inhibitory concentrations (subMICs) of the extracts and isolated compounds inhibited selected Pseudomonasaeruginosa PAO1 virulence determinants. The most reduced growth of P. aeruginosa colony was in the presence of isolated oxypeucedanin. Ethanol (17.36-46.98%) and methanol (34.54-52.43%) root extracts showed higher anti-biofilm activity compared to streptomycin (49.40-88.36%) and ampicillin (56.46-92.16%).
PB  - American Chemical Society (ACS)
T2  - Journal of Agricultural and Food Chemistry
T1  - Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots
VL  - 65
IS  - 50
SP  - 10933
EP  - 10949
DO  - 10.1021/acs.jafc.7b04202
ER  - 

@article{
author = "Mileski, Ksenija S. and Trifunović, Snežana and Ciric, Ana D. and Sakic, Zeljana M. and Ristic, Mihailo S. and Todorović, Nina and Matevski, Vlado S. and Marin, Petar D. and Tešević, Vele and Dzamic, Ana M.",
year = "2017",
abstract = "The essential oil, different extracts, and isolated compounds of Angelica pancicii Vandas (Apiaceae) were investigated for the first time. The GC-FID and GC-MS analyses revealed sesquiterpenoids as the main constituents of A. pancicii essential oil of aerial parts with bornyl acetate (8.08%), n-octanol (5.82%), kessane (4.26%), and beta-selinene (4.26%) as the main constituents. Analysis of methanol extracts, using an HPLC-DAD/ESI-ToF-MS system, showed a total of 52 compounds in the aerial parts and 53 in the roots, indicating coumarins as the main constituents. In addition, new chromone (1) and six known furanocoumarins (2-7) were isolated from the roots and structurally elucidated by combined spectroscopic methods. The aerial part extracts exhibited higher polyphenolic contents and antioxidant activity evaluated by three radical scavenging assays. Using a microwell dilution method, the strongest antibacterial activity profiles were determined for ethanol and methanol root extracts (minimum bactericidal concentrations (MBCs) = 0.25-3.00 mg/mL), which were comparable to the activity of streptomycin (MBCs = 0.34-1.24 mg/mL), while the strongest antibacterial compound of A. pancicii was oxypeucedanin hydrate (MBCs = 0.50-8.00 mg/mL). Antifungal potential was in moderate extent, and the highest activity was obtained for root methanol extract (minimum fungicidal concentrations (MFCs) = 4.00-14.00 mg/mL). Tested sub-minimum inhibitory concentrations (subMICs) of the extracts and isolated compounds inhibited selected Pseudomonasaeruginosa PAO1 virulence determinants. The most reduced growth of P. aeruginosa colony was in the presence of isolated oxypeucedanin. Ethanol (17.36-46.98%) and methanol (34.54-52.43%) root extracts showed higher anti-biofilm activity compared to streptomycin (49.40-88.36%) and ampicillin (56.46-92.16%).",
publisher = "American Chemical Society (ACS)",
journal = "Journal of Agricultural and Food Chemistry",
title = "Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots",
volume = "65",
number = "50",
pages = "10933-10949",
doi = "10.1021/acs.jafc.7b04202"
}

Mileski, K. S., Trifunović, S., Ciric, A. D., Sakic, Z. M., Ristic, M. S., Todorović, N., Matevski, V. S., Marin, P. D., Tešević, V.,& Dzamic, A. M.. (2017). Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots. in Journal of Agricultural and Food Chemistry
American Chemical Society (ACS)., 65(50), 10933-10949.
https://doi.org/10.1021/acs.jafc.7b04202

Mileski KS, Trifunović S, Ciric AD, Sakic ZM, Ristic MS, Todorović N, Matevski VS, Marin PD, Tešević V, Dzamic AM. Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots. in Journal of Agricultural and Food Chemistry. 2017;65(50):10933-10949.
doi:10.1021/acs.jafc.7b04202 .

Mileski, Ksenija S., Trifunović, Snežana, Ciric, Ana D., Sakic, Zeljana M., Ristic, Mihailo S., Todorović, Nina, Matevski, Vlado S., Marin, Petar D., Tešević, Vele, Dzamic, Ana M., "Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots" in Journal of Agricultural and Food Chemistry, 65, no. 50 (2017):10933-10949,
https://doi.org/10.1021/acs.jafc.7b04202 . .

TY  - JOUR
AU  - Mileski, Ksenija S.
AU  - Trifunović, Snežana
AU  - Ciric, Ana D.
AU  - Sakic, Zeljana M.
AU  - Ristic, Mihailo S.
AU  - Todorović, Nina
AU  - Matevski, Vlado S.
AU  - Marin, Petar D.
AU  - Tešević, Vele
AU  - Dzamic, Ana M.
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2110
AB  - The essential oil, different extracts, and isolated compounds of Angelica pancicii Vandas (Apiaceae) were investigated for the first time. The GC-FID and GC-MS analyses revealed sesquiterpenoids as the main constituents of A. pancicii essential oil of aerial parts with bornyl acetate (8.08%), n-octanol (5.82%), kessane (4.26%), and beta-selinene (4.26%) as the main constituents. Analysis of methanol extracts, using an HPLC-DAD/ESI-ToF-MS system, showed a total of 52 compounds in the aerial parts and 53 in the roots, indicating coumarins as the main constituents. In addition, new chromone (1) and six known furanocoumarins (2-7) were isolated from the roots and structurally elucidated by combined spectroscopic methods. The aerial part extracts exhibited higher polyphenolic contents and antioxidant activity evaluated by three radical scavenging assays. Using a microwell dilution method, the strongest antibacterial activity profiles were determined for ethanol and methanol root extracts (minimum bactericidal concentrations (MBCs) = 0.25-3.00 mg/mL), which were comparable to the activity of streptomycin (MBCs = 0.34-1.24 mg/mL), while the strongest antibacterial compound of A. pancicii was oxypeucedanin hydrate (MBCs = 0.50-8.00 mg/mL). Antifungal potential was in moderate extent, and the highest activity was obtained for root methanol extract (minimum fungicidal concentrations (MFCs) = 4.00-14.00 mg/mL). Tested sub-minimum inhibitory concentrations (subMICs) of the extracts and isolated compounds inhibited selected Pseudomonasaeruginosa PAO1 virulence determinants. The most reduced growth of P. aeruginosa colony was in the presence of isolated oxypeucedanin. Ethanol (17.36-46.98%) and methanol (34.54-52.43%) root extracts showed higher anti-biofilm activity compared to streptomycin (49.40-88.36%) and ampicillin (56.46-92.16%).
PB  - American Chemical Society (ACS)
T2  - Journal of Agricultural and Food Chemistry
T1  - Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots
VL  - 65
IS  - 50
SP  - 10933
EP  - 10949
DO  - 10.1021/acs.jafc.7b04202
ER  - 

@article{
author = "Mileski, Ksenija S. and Trifunović, Snežana and Ciric, Ana D. and Sakic, Zeljana M. and Ristic, Mihailo S. and Todorović, Nina and Matevski, Vlado S. and Marin, Petar D. and Tešević, Vele and Dzamic, Ana M.",
year = "2017",
abstract = "The essential oil, different extracts, and isolated compounds of Angelica pancicii Vandas (Apiaceae) were investigated for the first time. The GC-FID and GC-MS analyses revealed sesquiterpenoids as the main constituents of A. pancicii essential oil of aerial parts with bornyl acetate (8.08%), n-octanol (5.82%), kessane (4.26%), and beta-selinene (4.26%) as the main constituents. Analysis of methanol extracts, using an HPLC-DAD/ESI-ToF-MS system, showed a total of 52 compounds in the aerial parts and 53 in the roots, indicating coumarins as the main constituents. In addition, new chromone (1) and six known furanocoumarins (2-7) were isolated from the roots and structurally elucidated by combined spectroscopic methods. The aerial part extracts exhibited higher polyphenolic contents and antioxidant activity evaluated by three radical scavenging assays. Using a microwell dilution method, the strongest antibacterial activity profiles were determined for ethanol and methanol root extracts (minimum bactericidal concentrations (MBCs) = 0.25-3.00 mg/mL), which were comparable to the activity of streptomycin (MBCs = 0.34-1.24 mg/mL), while the strongest antibacterial compound of A. pancicii was oxypeucedanin hydrate (MBCs = 0.50-8.00 mg/mL). Antifungal potential was in moderate extent, and the highest activity was obtained for root methanol extract (minimum fungicidal concentrations (MFCs) = 4.00-14.00 mg/mL). Tested sub-minimum inhibitory concentrations (subMICs) of the extracts and isolated compounds inhibited selected Pseudomonasaeruginosa PAO1 virulence determinants. The most reduced growth of P. aeruginosa colony was in the presence of isolated oxypeucedanin. Ethanol (17.36-46.98%) and methanol (34.54-52.43%) root extracts showed higher anti-biofilm activity compared to streptomycin (49.40-88.36%) and ampicillin (56.46-92.16%).",
publisher = "American Chemical Society (ACS)",
journal = "Journal of Agricultural and Food Chemistry",
title = "Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots",
volume = "65",
number = "50",
pages = "10933-10949",
doi = "10.1021/acs.jafc.7b04202"
}

Mileski, K. S., Trifunović, S., Ciric, A. D., Sakic, Z. M., Ristic, M. S., Todorović, N., Matevski, V. S., Marin, P. D., Tešević, V.,& Dzamic, A. M.. (2017). Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots. in Journal of Agricultural and Food Chemistry
American Chemical Society (ACS)., 65(50), 10933-10949.
https://doi.org/10.1021/acs.jafc.7b04202

Mileski KS, Trifunović S, Ciric AD, Sakic ZM, Ristic MS, Todorović N, Matevski VS, Marin PD, Tešević V, Dzamic AM. Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots. in Journal of Agricultural and Food Chemistry. 2017;65(50):10933-10949.
doi:10.1021/acs.jafc.7b04202 .

Mileski, Ksenija S., Trifunović, Snežana, Ciric, Ana D., Sakic, Zeljana M., Ristic, Mihailo S., Todorović, Nina, Matevski, Vlado S., Marin, Petar D., Tešević, Vele, Dzamic, Ana M., "Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots" in Journal of Agricultural and Food Chemistry, 65, no. 50 (2017):10933-10949,
https://doi.org/10.1021/acs.jafc.7b04202 . .

TY  - JOUR
AU  - Bukvicki, Danka
AU  - Ciric, Ana
AU  - Soković, Marina
AU  - Vannini, Lucia
AU  - Nissen, Lorenzo
AU  - Novaković, Miroslav
AU  - Vujisić, Ljubodrag V.
AU  - Asakawa, Yoshinori
AU  - Marin, Petar D.
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1906
AB  - The chemical composition, antimicrobial and antiquorum sensing activity of the essential oil of Micromeria thymifolia (Scop.) Fritsch were investigated. Limonene, piperitone epoxide and piperitenone epoxide were found as the main constituents using a gas chromatography-mass spectrometry technique. In vitro antimicrobial activity of the oil was tested against six bacterial and seven fungal strains and high antimicrobial potential was noticed. Minimum inhibitory concentration varied from 0.031 mg/mL to 0.5 mg/mL for bacterial and 0.062 mg/mL to 0.5 mg/mL for fungal strains. The antiquorum properties of the essential oil were evaluated on Pseudomonas aeruginosa PAO1. The oil was tested at subMiC concentrations for anti-quorum sensing activity. The analyses on quorum-sensing functions have been carried out by evaluating twitching and swarming of bacterial cultures and the total amount of pyocyanin production produced by P. aeruginosa. This study showed that M thymifolia essential oil exhibited antiquorum sensing activity and may be used as an antipathogenic drug.
PB  - Natural Products Inc, Westerville
T2  - Natural Product Communications
T1  - Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa
VL  - 11
IS  - 12
SP  - 1903
EP  - 1906
UR  - https://hdl.handle.net/21.15107/rcub_cherry_2374
ER  - 

@article{
author = "Bukvicki, Danka and Ciric, Ana and Soković, Marina and Vannini, Lucia and Nissen, Lorenzo and Novaković, Miroslav and Vujisić, Ljubodrag V. and Asakawa, Yoshinori and Marin, Petar D.",
year = "2016",
abstract = "The chemical composition, antimicrobial and antiquorum sensing activity of the essential oil of Micromeria thymifolia (Scop.) Fritsch were investigated. Limonene, piperitone epoxide and piperitenone epoxide were found as the main constituents using a gas chromatography-mass spectrometry technique. In vitro antimicrobial activity of the oil was tested against six bacterial and seven fungal strains and high antimicrobial potential was noticed. Minimum inhibitory concentration varied from 0.031 mg/mL to 0.5 mg/mL for bacterial and 0.062 mg/mL to 0.5 mg/mL for fungal strains. The antiquorum properties of the essential oil were evaluated on Pseudomonas aeruginosa PAO1. The oil was tested at subMiC concentrations for anti-quorum sensing activity. The analyses on quorum-sensing functions have been carried out by evaluating twitching and swarming of bacterial cultures and the total amount of pyocyanin production produced by P. aeruginosa. This study showed that M thymifolia essential oil exhibited antiquorum sensing activity and may be used as an antipathogenic drug.",
publisher = "Natural Products Inc, Westerville",
journal = "Natural Product Communications",
title = "Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa",
volume = "11",
number = "12",
pages = "1903-1906",
url = "https://hdl.handle.net/21.15107/rcub_cherry_2374"
}

Bukvicki, D., Ciric, A., Soković, M., Vannini, L., Nissen, L., Novaković, M., Vujisić, L. V., Asakawa, Y.,& Marin, P. D.. (2016). Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa. in Natural Product Communications
Natural Products Inc, Westerville., 11(12), 1903-1906.
https://hdl.handle.net/21.15107/rcub_cherry_2374

Bukvicki D, Ciric A, Soković M, Vannini L, Nissen L, Novaković M, Vujisić LV, Asakawa Y, Marin PD. Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa. in Natural Product Communications. 2016;11(12):1903-1906.
https://hdl.handle.net/21.15107/rcub_cherry_2374 .

Bukvicki, Danka, Ciric, Ana, Soković, Marina, Vannini, Lucia, Nissen, Lorenzo, Novaković, Miroslav, Vujisić, Ljubodrag V., Asakawa, Yoshinori, Marin, Petar D., "Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa" in Natural Product Communications, 11, no. 12 (2016):1903-1906,
https://hdl.handle.net/21.15107/rcub_cherry_2374 .

TY  - JOUR
AU  - Mileski, Ksenija S
AU  - Ciric, Ana D
AU  - Trifunović, Snežana
AU  - Ristic, Mihailo S
AU  - Soković, Marina
AU  - Matevski, Vlado S
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Marin, Petar D.
AU  - Dzamic, Ana M
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3130
AB  - GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.
PB  - Royal Soc Chemistry, Cambridge
T2  - Food & Function
T1  - Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
VL  - 7
IS  - 9
SP  - 4061
EP  - 4074
DO  - 10.1039/c6fo01018k
ER  - 

@article{
author = "Mileski, Ksenija S and Ciric, Ana D and Trifunović, Snežana and Ristic, Mihailo S and Soković, Marina and Matevski, Vlado S and Tešević, Vele and Jadranin, Milka and Marin, Petar D. and Dzamic, Ana M",
year = "2016",
abstract = "GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Food & Function",
title = "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1",
volume = "7",
number = "9",
pages = "4061-4074",
doi = "10.1039/c6fo01018k"
}

Mileski, K. S., Ciric, A. D., Trifunović, S., Ristic, M. S., Soković, M., Matevski, V. S., Tešević, V., Jadranin, M., Marin, P. D.,& Dzamic, A. M.. (2016). Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food & Function
Royal Soc Chemistry, Cambridge., 7(9), 4061-4074.
https://doi.org/10.1039/c6fo01018k

Mileski KS, Ciric AD, Trifunović S, Ristic MS, Soković M, Matevski VS, Tešević V, Jadranin M, Marin PD, Dzamic AM. Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food & Function. 2016;7(9):4061-4074.
doi:10.1039/c6fo01018k .

Mileski, Ksenija S, Ciric, Ana D, Trifunović, Snežana, Ristic, Mihailo S, Soković, Marina, Matevski, Vlado S, Tešević, Vele, Jadranin, Milka, Marin, Petar D., Dzamic, Ana M, "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1" in Food & Function, 7, no. 9 (2016):4061-4074,
https://doi.org/10.1039/c6fo01018k . .

TY  - JOUR
AU  - Mileski, Ksenija S
AU  - Ciric, Ana D
AU  - Trifunović, Snežana
AU  - Ristic, Mihailo S
AU  - Soković, Marina
AU  - Matevski, Vlado S
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Marin, Petar D.
AU  - Dzamic, Ana M
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1923
AB  - GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.
PB  - Royal Soc Chemistry, Cambridge
T2  - Food & Function
T1  - Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
VL  - 7
IS  - 9
SP  - 4061
EP  - 4074
DO  - 10.1039/c6fo01018k
ER  - 

@article{
author = "Mileski, Ksenija S and Ciric, Ana D and Trifunović, Snežana and Ristic, Mihailo S and Soković, Marina and Matevski, Vlado S and Tešević, Vele and Jadranin, Milka and Marin, Petar D. and Dzamic, Ana M",
year = "2016",
abstract = "GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Food & Function",
title = "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1",
volume = "7",
number = "9",
pages = "4061-4074",
doi = "10.1039/c6fo01018k"
}

Mileski, K. S., Ciric, A. D., Trifunović, S., Ristic, M. S., Soković, M., Matevski, V. S., Tešević, V., Jadranin, M., Marin, P. D.,& Dzamic, A. M.. (2016). Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food & Function
Royal Soc Chemistry, Cambridge., 7(9), 4061-4074.
https://doi.org/10.1039/c6fo01018k

Mileski KS, Ciric AD, Trifunović S, Ristic MS, Soković M, Matevski VS, Tešević V, Jadranin M, Marin PD, Dzamic AM. Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food & Function. 2016;7(9):4061-4074.
doi:10.1039/c6fo01018k .

Mileski, Ksenija S, Ciric, Ana D, Trifunović, Snežana, Ristic, Mihailo S, Soković, Marina, Matevski, Vlado S, Tešević, Vele, Jadranin, Milka, Marin, Petar D., Dzamic, Ana M, "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1" in Food & Function, 7, no. 9 (2016):4061-4074,
https://doi.org/10.1039/c6fo01018k . .

TY  - JOUR
AU  - Rajčević, Nemanja
AU  - Marin, Petar D.
AU  - Vujisić, Ljubodrag V.
AU  - Krivosej, Zoran
AU  - Vajs, Vlatka
AU  - Janaćković, Peđa T.
PY  - 2015
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2724
AB  - The composition of essential oil isolated from the areal parts of Aster albanicus Deg, an endemic species of the central Balkans, was analyzed. In total, 111 compounds were identified, representing 98% of the essential oil. The essential oil was dominated by sesquiterpene (69.3%) and monoterpene hydrocarbons (15.9%), with germacrene D as the most abundant compound (34.7%). Several multivariant statistical methods (HCA, NJ, PCoA) were deployed to infer the relation between A. albanicus and other species belonging to this genus. Taxonomical implications are discussed.
PB  - Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd
T2  - Archives of biological sciences
T1  - Chemical Composition of Aster Albanicus Deg. (Asteraceae) Essential Oil: Taxonomical Implications
VL  - 67
IS  - 3
SP  - 1055
EP  - 1061
DO  - 10.2298/ABS150223068R
ER  - 

@article{
author = "Rajčević, Nemanja and Marin, Petar D. and Vujisić, Ljubodrag V. and Krivosej, Zoran and Vajs, Vlatka and Janaćković, Peđa T.",
year = "2015",
abstract = "The composition of essential oil isolated from the areal parts of Aster albanicus Deg, an endemic species of the central Balkans, was analyzed. In total, 111 compounds were identified, representing 98% of the essential oil. The essential oil was dominated by sesquiterpene (69.3%) and monoterpene hydrocarbons (15.9%), with germacrene D as the most abundant compound (34.7%). Several multivariant statistical methods (HCA, NJ, PCoA) were deployed to infer the relation between A. albanicus and other species belonging to this genus. Taxonomical implications are discussed.",
publisher = "Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd",
journal = "Archives of biological sciences",
title = "Chemical Composition of Aster Albanicus Deg. (Asteraceae) Essential Oil: Taxonomical Implications",
volume = "67",
number = "3",
pages = "1055-1061",
doi = "10.2298/ABS150223068R"
}

Rajčević, N., Marin, P. D., Vujisić, L. V., Krivosej, Z., Vajs, V.,& Janaćković, P. T.. (2015). Chemical Composition of Aster Albanicus Deg. (Asteraceae) Essential Oil: Taxonomical Implications. in Archives of biological sciences
Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd., 67(3), 1055-1061.
https://doi.org/10.2298/ABS150223068R

Rajčević N, Marin PD, Vujisić LV, Krivosej Z, Vajs V, Janaćković PT. Chemical Composition of Aster Albanicus Deg. (Asteraceae) Essential Oil: Taxonomical Implications. in Archives of biological sciences. 2015;67(3):1055-1061.
doi:10.2298/ABS150223068R .

Rajčević, Nemanja, Marin, Petar D., Vujisić, Ljubodrag V., Krivosej, Zoran, Vajs, Vlatka, Janaćković, Peđa T., "Chemical Composition of Aster Albanicus Deg. (Asteraceae) Essential Oil: Taxonomical Implications" in Archives of biological sciences, 67, no. 3 (2015):1055-1061,
https://doi.org/10.2298/ABS150223068R . .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Tešević, Vele
AU  - Đorđević, Iris
AU  - Todosijević, Marina
AU  - Jadranin, Milka
AU  - Bojovic, Srdjan
AU  - Marin, Petar D.
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1295
AB  - This is the first report of population variability of the contents of n-alkanes and nonacosan-10-ol in the needle epicuticular waxes of Serbian spruce (Picea omorika). The hexane extracts of needle samples originated from three natural populations in Serbia (Vranjak, Zmajevaki potok, and Mileevka Canyon) were investigated by GC and GC/MS analyses. The amount of nonacosan-10-ol varied individually from 50.05 to 74.42% (65.74% in average), but the differences between the three investigated populations were not statistically confirmed. The results exhibited variability of the composition of n-alkanes in the epicuticular waxes with their size ranging from C18 to C35. The most abundant n-alkanes were C29, C31, and C27 (35.22, 13.77, and 12.28% in average, resp.). The carbon preference index of all the n-alkanes (CPItotal) of the P. omorika populations (average of populations IIII) ranged from 3.3 to 11.5 (mean of 5.9), while the average chain length (ACL) ranged from 26.6 to 29.2. The principal component and cluster analyses of the contents of nine n-alkanes showed the greatest difference for the population growing in the Mileevka Canyon. The obtained results were compared with previous literature data given for other Picea species, and this comparison was briefly discussed.
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - Chemistry & Biodiversity
T1  - Variability of n-Alkanes and Nonacosan-10-ol in Natural Populations of Picea omorika
VL  - 10
IS  - 3
SP  - 473
EP  - 483
DO  - 10.1002/cbdv.201200271
ER  - 

@article{
author = "Nikolić, Biljana and Tešević, Vele and Đorđević, Iris and Todosijević, Marina and Jadranin, Milka and Bojovic, Srdjan and Marin, Petar D.",
year = "2013",
abstract = "This is the first report of population variability of the contents of n-alkanes and nonacosan-10-ol in the needle epicuticular waxes of Serbian spruce (Picea omorika). The hexane extracts of needle samples originated from three natural populations in Serbia (Vranjak, Zmajevaki potok, and Mileevka Canyon) were investigated by GC and GC/MS analyses. The amount of nonacosan-10-ol varied individually from 50.05 to 74.42% (65.74% in average), but the differences between the three investigated populations were not statistically confirmed. The results exhibited variability of the composition of n-alkanes in the epicuticular waxes with their size ranging from C18 to C35. The most abundant n-alkanes were C29, C31, and C27 (35.22, 13.77, and 12.28% in average, resp.). The carbon preference index of all the n-alkanes (CPItotal) of the P. omorika populations (average of populations IIII) ranged from 3.3 to 11.5 (mean of 5.9), while the average chain length (ACL) ranged from 26.6 to 29.2. The principal component and cluster analyses of the contents of nine n-alkanes showed the greatest difference for the population growing in the Mileevka Canyon. The obtained results were compared with previous literature data given for other Picea species, and this comparison was briefly discussed.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Chemistry & Biodiversity",
title = "Variability of n-Alkanes and Nonacosan-10-ol in Natural Populations of Picea omorika",
volume = "10",
number = "3",
pages = "473-483",
doi = "10.1002/cbdv.201200271"
}

Nikolić, B., Tešević, V., Đorđević, I., Todosijević, M., Jadranin, M., Bojovic, S.,& Marin, P. D.. (2013). Variability of n-Alkanes and Nonacosan-10-ol in Natural Populations of Picea omorika. in Chemistry & Biodiversity
Wiley-V C H Verlag Gmbh, Weinheim., 10(3), 473-483.
https://doi.org/10.1002/cbdv.201200271

Nikolić B, Tešević V, Đorđević I, Todosijević M, Jadranin M, Bojovic S, Marin PD. Variability of n-Alkanes and Nonacosan-10-ol in Natural Populations of Picea omorika. in Chemistry & Biodiversity. 2013;10(3):473-483.
doi:10.1002/cbdv.201200271 .

Nikolić, Biljana, Tešević, Vele, Đorđević, Iris, Todosijević, Marina, Jadranin, Milka, Bojovic, Srdjan, Marin, Petar D., "Variability of n-Alkanes and Nonacosan-10-ol in Natural Populations of Picea omorika" in Chemistry & Biodiversity, 10, no. 3 (2013):473-483,
https://doi.org/10.1002/cbdv.201200271 . .

TY  - JOUR
AU  - Dzamic, Ana M.
AU  - Soković, Marina
AU  - Novaković, Miroslav
AU  - Jadranin, Milka
AU  - Ristic, Mihailo S.
AU  - Tešević, Vele
AU  - Marin, Petar D.
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1242
AB  - The aim of the study was to investigate the chemical composition of Hyssopus officinalis L subsp. pilifer (Pant.) Murb. essential oil (EO) and deodorized extracts (DE) and to evaluate their potential antifungal and antioxidant activities. EO was analyzed by GC-FID and GC-MS. Among the 30 compounds identified in the oil, the main were 1.8-cineole (36.43%), beta-pinene (19.55%), isopinocamphone (15.32%) and trans-pinocamphone (6.39%). Deodorized aqueous extract (DAE) was analyzed by LC-DAD/ESI-TOF MS. The most significant phenolic acids detected in DAE were syringic, caffeoylqunic acids, feruloylquinic and rosmarinic acid. Aspergillus niger, A. ochraceus, A. versicolor, A. fumigatus, Cladosporium cladosporioides, C. fulvum, Penicillium funiculosum, P. ochrochloron, Trichoderma viride and Candida albicans yeast were used for antifungal assay. Minimum inhibitory concentrations (MICs) and minimum fungicidal concentrations (MFCs) of the tested EO and DEs were recorded by the microdilution method. The antioxidant potential of the extracts was evaluated by means of the 2,2-diphenyl-1-picrylhydrazil (DPPH) radical scavenging method. The deodorized aqueous extract (DAE) possessed the highest scavenging activity (EC50=0.54 mg/ml) followed by the deodorized methanol extract (DME) (EC50=0.82 mg/ml) and deodorized ethyl acetate extract (DEE) (EC50 = 2.97 mg/ml). EC/possessed the lowest activities compared to other extracts and control substances. Total phenolic content of DEs was determined by Folin-Ciocalteau (FC) assay and gallic acid was used as the standard. DAE of H. officinalis subsp. pilifer exhibited the highest phenolic content 96.47 GAE.
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - Composition, antifungal and antioxidant properties of Hyssopus officinalis L. subsp pilifer (Pant.) Murb. essential oil and deodorized extracts
VL  - 51
SP  - 401
EP  - 407
DO  - 10.1016/j.indcrop.2013.09.038
ER  - 

@article{
author = "Dzamic, Ana M. and Soković, Marina and Novaković, Miroslav and Jadranin, Milka and Ristic, Mihailo S. and Tešević, Vele and Marin, Petar D.",
year = "2013",
abstract = "The aim of the study was to investigate the chemical composition of Hyssopus officinalis L subsp. pilifer (Pant.) Murb. essential oil (EO) and deodorized extracts (DE) and to evaluate their potential antifungal and antioxidant activities. EO was analyzed by GC-FID and GC-MS. Among the 30 compounds identified in the oil, the main were 1.8-cineole (36.43%), beta-pinene (19.55%), isopinocamphone (15.32%) and trans-pinocamphone (6.39%). Deodorized aqueous extract (DAE) was analyzed by LC-DAD/ESI-TOF MS. The most significant phenolic acids detected in DAE were syringic, caffeoylqunic acids, feruloylquinic and rosmarinic acid. Aspergillus niger, A. ochraceus, A. versicolor, A. fumigatus, Cladosporium cladosporioides, C. fulvum, Penicillium funiculosum, P. ochrochloron, Trichoderma viride and Candida albicans yeast were used for antifungal assay. Minimum inhibitory concentrations (MICs) and minimum fungicidal concentrations (MFCs) of the tested EO and DEs were recorded by the microdilution method. The antioxidant potential of the extracts was evaluated by means of the 2,2-diphenyl-1-picrylhydrazil (DPPH) radical scavenging method. The deodorized aqueous extract (DAE) possessed the highest scavenging activity (EC50=0.54 mg/ml) followed by the deodorized methanol extract (DME) (EC50=0.82 mg/ml) and deodorized ethyl acetate extract (DEE) (EC50 = 2.97 mg/ml). EC/possessed the lowest activities compared to other extracts and control substances. Total phenolic content of DEs was determined by Folin-Ciocalteau (FC) assay and gallic acid was used as the standard. DAE of H. officinalis subsp. pilifer exhibited the highest phenolic content 96.47 GAE.",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "Composition, antifungal and antioxidant properties of Hyssopus officinalis L. subsp pilifer (Pant.) Murb. essential oil and deodorized extracts",
volume = "51",
pages = "401-407",
doi = "10.1016/j.indcrop.2013.09.038"
}

Dzamic, A. M., Soković, M., Novaković, M., Jadranin, M., Ristic, M. S., Tešević, V.,& Marin, P. D.. (2013). Composition, antifungal and antioxidant properties of Hyssopus officinalis L. subsp pilifer (Pant.) Murb. essential oil and deodorized extracts. in Industrial Crops and Products
Elsevier., 51, 401-407.
https://doi.org/10.1016/j.indcrop.2013.09.038

Dzamic AM, Soković M, Novaković M, Jadranin M, Ristic MS, Tešević V, Marin PD. Composition, antifungal and antioxidant properties of Hyssopus officinalis L. subsp pilifer (Pant.) Murb. essential oil and deodorized extracts. in Industrial Crops and Products. 2013;51:401-407.
doi:10.1016/j.indcrop.2013.09.038 .

Dzamic, Ana M., Soković, Marina, Novaković, Miroslav, Jadranin, Milka, Ristic, Mihailo S., Tešević, Vele, Marin, Petar D., "Composition, antifungal and antioxidant properties of Hyssopus officinalis L. subsp pilifer (Pant.) Murb. essential oil and deodorized extracts" in Industrial Crops and Products, 51 (2013):401-407,
https://doi.org/10.1016/j.indcrop.2013.09.038 . .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Tešević, Vele
AU  - Đorđević, Iris
AU  - Todosijević, Marina
AU  - Jadranin, Milka
AU  - Bojovic, Srdjan
AU  - Marin, Petar D.
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/985
AB  - This is the first report on population variability of nonacosan-10-ol and n-alkanes in needle epicuticular waxes of Macedonian pine (Pinus peuce Griseb.) Hexane extracts of needle samples, originating from two natural populations in Montenegro (Zeletin and Sjekirica) and from one population in Serbia (Mokra Gora) were analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). The amount of nonacosan-10-ol varied individually from 41.3 to 72.31% (average 55.9%), with the Sjekirica population being statistically divergent (64.4% on average). The results showed n-alkanes in epicuticular waxes ranging from C18 to C33. The most abundant alkanes were C29, C25, C27, and C23 (15.5, 11.1, 10.6, and 10.5% on average, resp.). The carbon preference index of Pinus peuce ranged from 1.0 to 4.3 (1.9 on average). Average chain length ranged from 18.4 to 27.7 (average 25.7). A high level of inidividual quantitative variation in all of these hydrocarbon parameters was also detected. These results were compared with published data on other species from the Pinus genus.
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - Chemistry & Biodiversity
T1  - Population Variability of Nonacosan-10-ol and n-Alkanes in Needle Cuticular Waxes of Macedonian Pine (Pinus peuce Griseb.)
VL  - 9
IS  - 6
SP  - 1155
EP  - 1165
DO  - 10.1002/cbdv.201100316
ER  - 

@article{
author = "Nikolić, Biljana and Tešević, Vele and Đorđević, Iris and Todosijević, Marina and Jadranin, Milka and Bojovic, Srdjan and Marin, Petar D.",
year = "2012",
abstract = "This is the first report on population variability of nonacosan-10-ol and n-alkanes in needle epicuticular waxes of Macedonian pine (Pinus peuce Griseb.) Hexane extracts of needle samples, originating from two natural populations in Montenegro (Zeletin and Sjekirica) and from one population in Serbia (Mokra Gora) were analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). The amount of nonacosan-10-ol varied individually from 41.3 to 72.31% (average 55.9%), with the Sjekirica population being statistically divergent (64.4% on average). The results showed n-alkanes in epicuticular waxes ranging from C18 to C33. The most abundant alkanes were C29, C25, C27, and C23 (15.5, 11.1, 10.6, and 10.5% on average, resp.). The carbon preference index of Pinus peuce ranged from 1.0 to 4.3 (1.9 on average). Average chain length ranged from 18.4 to 27.7 (average 25.7). A high level of inidividual quantitative variation in all of these hydrocarbon parameters was also detected. These results were compared with published data on other species from the Pinus genus.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Chemistry & Biodiversity",
title = "Population Variability of Nonacosan-10-ol and n-Alkanes in Needle Cuticular Waxes of Macedonian Pine (Pinus peuce Griseb.)",
volume = "9",
number = "6",
pages = "1155-1165",
doi = "10.1002/cbdv.201100316"
}

Nikolić, B., Tešević, V., Đorđević, I., Todosijević, M., Jadranin, M., Bojovic, S.,& Marin, P. D.. (2012). Population Variability of Nonacosan-10-ol and n-Alkanes in Needle Cuticular Waxes of Macedonian Pine (Pinus peuce Griseb.). in Chemistry & Biodiversity
Wiley-V C H Verlag Gmbh, Weinheim., 9(6), 1155-1165.
https://doi.org/10.1002/cbdv.201100316

Nikolić B, Tešević V, Đorđević I, Todosijević M, Jadranin M, Bojovic S, Marin PD. Population Variability of Nonacosan-10-ol and n-Alkanes in Needle Cuticular Waxes of Macedonian Pine (Pinus peuce Griseb.). in Chemistry & Biodiversity. 2012;9(6):1155-1165.
doi:10.1002/cbdv.201100316 .

Nikolić, Biljana, Tešević, Vele, Đorđević, Iris, Todosijević, Marina, Jadranin, Milka, Bojovic, Srdjan, Marin, Petar D., "Population Variability of Nonacosan-10-ol and n-Alkanes in Needle Cuticular Waxes of Macedonian Pine (Pinus peuce Griseb.)" in Chemistry & Biodiversity, 9, no. 6 (2012):1155-1165,
https://doi.org/10.1002/cbdv.201100316 . .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Tešević, Vele
AU  - Đorđević, Iris
AU  - Todosijević, Marina
AU  - Jadranin, Milka
AU  - Bojovic, Srdjan
AU  - Marin, Petar D.
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1006
AB  - This is the first report of individual variability and population diversity of the contents of nonacosan-10-ol and n-alkanes in the needle cuticular waxes of Bosnian pines originated from Montenegro, regarded as Pinus heldreichii var. leucodermis, and from Serbia, regarded as P. heldreichii var. pancici. The amount of nonacosan-10-ol varied individually from 27.4 to 73.2% (55.5% in average), but differences between the four investigated populations were not statistically confirmed. The size of the n-alkanes ranged from C18 to C33. The most abundant n-alkanes were C23, C27, and C25 (12.2, 11.2, and 10.8% in average, resp.). The carbon preference index (CPI) of the n-alkanes ranged from 0.8 to 3.1 (1.6 in average), while the average chain length (ACL) ranged from 20.9 to 26.5 (24.4 in average). Long-chain and mid-chain n-alkanes prevailed (49.6 and 37.9% in average, resp.). It was also found that the populations of P. heldreichii var. leucodermis had predominantly a narrower range of n-alkanes (C18?C31) than the trees of the variety pancici (C18?C33). Differences between the varieties were also significant for most of the other characteristics of the n-alkane pattern (e.g., most abundant n-alkanes, CPI, ACL, and relative proportion of short-, mid-, and long-chain n-alkanes). The principle component and cluster analyses of eleven n-alkanes confirmed the significant diversity of these two varieties.
PB  - Wiley-Blackwell, Malden
T2  - Chemistry & Biodiversity
T1  - Chemodiversity of Nonacosan-10-ol and n-Alkanes in the Needle Wax of Pinus heldreichii
VL  - 9
IS  - 1
SP  - 80
EP  - 90
DO  - 10.1002/cbdv.201100179
ER  - 

@article{
author = "Nikolić, Biljana and Tešević, Vele and Đorđević, Iris and Todosijević, Marina and Jadranin, Milka and Bojovic, Srdjan and Marin, Petar D.",
year = "2012",
abstract = "This is the first report of individual variability and population diversity of the contents of nonacosan-10-ol and n-alkanes in the needle cuticular waxes of Bosnian pines originated from Montenegro, regarded as Pinus heldreichii var. leucodermis, and from Serbia, regarded as P. heldreichii var. pancici. The amount of nonacosan-10-ol varied individually from 27.4 to 73.2% (55.5% in average), but differences between the four investigated populations were not statistically confirmed. The size of the n-alkanes ranged from C18 to C33. The most abundant n-alkanes were C23, C27, and C25 (12.2, 11.2, and 10.8% in average, resp.). The carbon preference index (CPI) of the n-alkanes ranged from 0.8 to 3.1 (1.6 in average), while the average chain length (ACL) ranged from 20.9 to 26.5 (24.4 in average). Long-chain and mid-chain n-alkanes prevailed (49.6 and 37.9% in average, resp.). It was also found that the populations of P. heldreichii var. leucodermis had predominantly a narrower range of n-alkanes (C18?C31) than the trees of the variety pancici (C18?C33). Differences between the varieties were also significant for most of the other characteristics of the n-alkane pattern (e.g., most abundant n-alkanes, CPI, ACL, and relative proportion of short-, mid-, and long-chain n-alkanes). The principle component and cluster analyses of eleven n-alkanes confirmed the significant diversity of these two varieties.",
publisher = "Wiley-Blackwell, Malden",
journal = "Chemistry & Biodiversity",
title = "Chemodiversity of Nonacosan-10-ol and n-Alkanes in the Needle Wax of Pinus heldreichii",
volume = "9",
number = "1",
pages = "80-90",
doi = "10.1002/cbdv.201100179"
}

Nikolić, B., Tešević, V., Đorđević, I., Todosijević, M., Jadranin, M., Bojovic, S.,& Marin, P. D.. (2012). Chemodiversity of Nonacosan-10-ol and n-Alkanes in the Needle Wax of Pinus heldreichii. in Chemistry & Biodiversity
Wiley-Blackwell, Malden., 9(1), 80-90.
https://doi.org/10.1002/cbdv.201100179

Nikolić B, Tešević V, Đorđević I, Todosijević M, Jadranin M, Bojovic S, Marin PD. Chemodiversity of Nonacosan-10-ol and n-Alkanes in the Needle Wax of Pinus heldreichii. in Chemistry & Biodiversity. 2012;9(1):80-90.
doi:10.1002/cbdv.201100179 .

Nikolić, Biljana, Tešević, Vele, Đorđević, Iris, Todosijević, Marina, Jadranin, Milka, Bojovic, Srdjan, Marin, Petar D., "Chemodiversity of Nonacosan-10-ol and n-Alkanes in the Needle Wax of Pinus heldreichii" in Chemistry & Biodiversity, 9, no. 1 (2012):80-90,
https://doi.org/10.1002/cbdv.201100179 . .

TY  - JOUR
AU  - Marin, Marija
AU  - Novaković, Miroslav
AU  - Tešević, Vele
AU  - Vučković, Ivan
AU  - Milojevic, Natasa
AU  - Vukovic-Gacic, Branka
AU  - Marin, Petar D.
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/965
AB  - The composition of the essential oil of Satureja montana was examined by gas chromatographymass spectrometry and 1H nuclear magnetic resonance spectroscopy. Forty-three compounds were identified, representing approximately 99% of the oil. Major components were ?-terpinene (8.7%), p-cymene (16.9%) and carvacrol (44.5%). The oil was tested for its antioxidant activity by using the 1,1-diphenyl-2-picryl hydrazyl assay and showed dose-dependent free-radical-scavenging activity with an EC50 value of 4.21 mg/ml. The antimicrobial effect of the essential oil was tested against six strains of Gram-negative bacteria, seven strains of Gram-positive bacteria and two fungi. The human pathogens Burkholderia cepacia ATCC 25416 (Gram negative) and Listeria innocua (Gram positive) were used in the investigation of S. montana for the first time. The minimum inhibitory concentration of the essential oil ranged from 0.625 to 5.0 mu l/well for Gram-negative bacteria, and from 0.312 to 1.125 mu l/well for Gram-positive bacteria. For the two fungi tested, Candida and Saccharomyces, the value was 0.234 mu l/tube. The essential oil tested showed significant activity against fungi and Gram-positive bacteria, especially Bacillus subtilis, Staphylococcus epidermidis and Listeria innocua, and among Gram-negative bacteria extreme sensitivity was detected in Escherichia coli SY252, SY252 lpcA and ATTCC 25922 strains. Copyright
PB  - Wiley-Blackwell, Malden
T2  - Flavour and Fragrance Journal
T1  - Antioxidative, antibacterial and antifungal activity of the essential oil of wild-growing Satureja montana L. from Dalmatia, Croatia
VL  - 27
IS  - 3
SP  - 216
EP  - 223
DO  - 10.1002/ffj.3082
ER  - 

@article{
author = "Marin, Marija and Novaković, Miroslav and Tešević, Vele and Vučković, Ivan and Milojevic, Natasa and Vukovic-Gacic, Branka and Marin, Petar D.",
year = "2012",
abstract = "The composition of the essential oil of Satureja montana was examined by gas chromatographymass spectrometry and 1H nuclear magnetic resonance spectroscopy. Forty-three compounds were identified, representing approximately 99% of the oil. Major components were ?-terpinene (8.7%), p-cymene (16.9%) and carvacrol (44.5%). The oil was tested for its antioxidant activity by using the 1,1-diphenyl-2-picryl hydrazyl assay and showed dose-dependent free-radical-scavenging activity with an EC50 value of 4.21 mg/ml. The antimicrobial effect of the essential oil was tested against six strains of Gram-negative bacteria, seven strains of Gram-positive bacteria and two fungi. The human pathogens Burkholderia cepacia ATCC 25416 (Gram negative) and Listeria innocua (Gram positive) were used in the investigation of S. montana for the first time. The minimum inhibitory concentration of the essential oil ranged from 0.625 to 5.0 mu l/well for Gram-negative bacteria, and from 0.312 to 1.125 mu l/well for Gram-positive bacteria. For the two fungi tested, Candida and Saccharomyces, the value was 0.234 mu l/tube. The essential oil tested showed significant activity against fungi and Gram-positive bacteria, especially Bacillus subtilis, Staphylococcus epidermidis and Listeria innocua, and among Gram-negative bacteria extreme sensitivity was detected in Escherichia coli SY252, SY252 lpcA and ATTCC 25922 strains. Copyright",
publisher = "Wiley-Blackwell, Malden",
journal = "Flavour and Fragrance Journal",
title = "Antioxidative, antibacterial and antifungal activity of the essential oil of wild-growing Satureja montana L. from Dalmatia, Croatia",
volume = "27",
number = "3",
pages = "216-223",
doi = "10.1002/ffj.3082"
}

Marin, M., Novaković, M., Tešević, V., Vučković, I., Milojevic, N., Vukovic-Gacic, B.,& Marin, P. D.. (2012). Antioxidative, antibacterial and antifungal activity of the essential oil of wild-growing Satureja montana L. from Dalmatia, Croatia. in Flavour and Fragrance Journal
Wiley-Blackwell, Malden., 27(3), 216-223.
https://doi.org/10.1002/ffj.3082

Marin M, Novaković M, Tešević V, Vučković I, Milojevic N, Vukovic-Gacic B, Marin PD. Antioxidative, antibacterial and antifungal activity of the essential oil of wild-growing Satureja montana L. from Dalmatia, Croatia. in Flavour and Fragrance Journal. 2012;27(3):216-223.
doi:10.1002/ffj.3082 .

Marin, Marija, Novaković, Miroslav, Tešević, Vele, Vučković, Ivan, Milojevic, Natasa, Vukovic-Gacic, Branka, Marin, Petar D., "Antioxidative, antibacterial and antifungal activity of the essential oil of wild-growing Satureja montana L. from Dalmatia, Croatia" in Flavour and Fragrance Journal, 27, no. 3 (2012):216-223,
https://doi.org/10.1002/ffj.3082 . .

TY  - JOUR
AU  - Gođevac, Dejan
AU  - Vujisić, Ljubodrag V.
AU  - Vučković, Ivan
AU  - Vajs, Vlatka
AU  - Soković, Marina
AU  - Marin, Petar D.
AU  - Tešević, Vele
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/980
AB  - An investigation of the chemical composition and antimicrobial activity of the essential oil of Galatella linosyris is presented. The chemical analysis (GC/MS, NMR) showed that sabinene (40 %), β-pinene (35.5 %), α-pinene (4.5 %), limonene (4 %), γ-muurolene (4 %), and (E)-caryophyllene (3.3 %) were dominant components in this oil. Microdilution assays were used to evaluate the minimum inhibitory concentration (MIC) and the minimum bactericidal/ fungicidal concentrations (MBC/MFC). G. linosyris essential oil exhibited better antibacterial activity against some of the tested bacteria than antifungal activity.
AB  - U ovom radu je prikazano ispitivanje hemijskog sastava i antimikrobne aktivnosti etarskog ulja biljne vrste Galatella linosyris. Hemijskom analizom (GC-MS i NMR) je utvrđeno da su glavni sastojci ovog etarskog ulja sabinen (40 %), β-pinen (35,5 %) , α-pinen (4,5 %), limonen (4 %), γ-muurolen (4 %) i (E)-kariofilen (3,3 %). Za procenu minimalne inhibitorne koncentracije (MIC) i minimalne baktericidne/fungicidne koncentracije (MBC/ /MFC) korišćeni su testovi mikrorazblaženja. Etarsko ulje G. linosyris je pokazalo bolju antibakterijsku nego antifungalnu aktivnost.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Composition and antimicrobial activity of the essential oil from Galatella linosyris (L.) Rchb. f. (Asteraceae)
T1  - Sastav i antimikrobna aktivnost etarskog ulja iz Galatella linosyris (L.) Rchb. f. (Asteraceae)
VL  - 77
IS  - 5
SP  - 619
EP  - 626
DO  - 10.2298/JSC110915213G
ER  - 

@article{
author = "Gođevac, Dejan and Vujisić, Ljubodrag V. and Vučković, Ivan and Vajs, Vlatka and Soković, Marina and Marin, Petar D. and Tešević, Vele",
year = "2012",
abstract = "An investigation of the chemical composition and antimicrobial activity of the essential oil of Galatella linosyris is presented. The chemical analysis (GC/MS, NMR) showed that sabinene (40 %), β-pinene (35.5 %), α-pinene (4.5 %), limonene (4 %), γ-muurolene (4 %), and (E)-caryophyllene (3.3 %) were dominant components in this oil. Microdilution assays were used to evaluate the minimum inhibitory concentration (MIC) and the minimum bactericidal/ fungicidal concentrations (MBC/MFC). G. linosyris essential oil exhibited better antibacterial activity against some of the tested bacteria than antifungal activity., U ovom radu je prikazano ispitivanje hemijskog sastava i antimikrobne aktivnosti etarskog ulja biljne vrste Galatella linosyris. Hemijskom analizom (GC-MS i NMR) je utvrđeno da su glavni sastojci ovog etarskog ulja sabinen (40 %), β-pinen (35,5 %) , α-pinen (4,5 %), limonen (4 %), γ-muurolen (4 %) i (E)-kariofilen (3,3 %). Za procenu minimalne inhibitorne koncentracije (MIC) i minimalne baktericidne/fungicidne koncentracije (MBC/ /MFC) korišćeni su testovi mikrorazblaženja. Etarsko ulje G. linosyris je pokazalo bolju antibakterijsku nego antifungalnu aktivnost.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Composition and antimicrobial activity of the essential oil from Galatella linosyris (L.) Rchb. f. (Asteraceae), Sastav i antimikrobna aktivnost etarskog ulja iz Galatella linosyris (L.) Rchb. f. (Asteraceae)",
volume = "77",
number = "5",
pages = "619-626",
doi = "10.2298/JSC110915213G"
}

Gođevac, D., Vujisić, L. V., Vučković, I., Vajs, V., Soković, M., Marin, P. D.,& Tešević, V.. (2012). Composition and antimicrobial activity of the essential oil from Galatella linosyris (L.) Rchb. f. (Asteraceae). in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 77(5), 619-626.
https://doi.org/10.2298/JSC110915213G

Gođevac D, Vujisić LV, Vučković I, Vajs V, Soković M, Marin PD, Tešević V. Composition and antimicrobial activity of the essential oil from Galatella linosyris (L.) Rchb. f. (Asteraceae). in Journal of the Serbian Chemical Society. 2012;77(5):619-626.
doi:10.2298/JSC110915213G .

Gođevac, Dejan, Vujisić, Ljubodrag V., Vučković, Ivan, Vajs, Vlatka, Soković, Marina, Marin, Petar D., Tešević, Vele, "Composition and antimicrobial activity of the essential oil from Galatella linosyris (L.) Rchb. f. (Asteraceae)" in Journal of the Serbian Chemical Society, 77, no. 5 (2012):619-626,
https://doi.org/10.2298/JSC110915213G . .

TY  - JOUR
AU  - Janaćković, Peđa T.
AU  - Soković, Marina
AU  - Vujisić, Ljubodrag V.
AU  - Vajs, Vlatka
AU  - Vučković, Ivan
AU  - Krivosej, Zoran
AU  - Marin, Petar D.
PY  - 2011
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2739
AB  - The essential oil from aerial parts of Seseli globiferum Vis. obtained by hydrodistillation with Clevenger-type apparatus was analyzed by GC-MS. Twenty-eight compounds were identified, representing 99.4% of the total oil. The main components of the oil were sabinene (38.0%), alpha-pinene (21.2%) and beta-phellandrene (13.5%). The microbial growth inhibitory properties of the isolated essential oil were determined using the broth microdilution method against seven bacterial species: Salmonella typhimurium (ATCC 13311), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Enterobacter cloacae (clinical isolates), Bacillus cereus (clinical isolates), Staphylococcus aureus (ATCC 25923), Staphylococcus epidermidis (ATCC 12228), Micrococcus flaw's (ATCC 10240) and three fungal species: Aspergillus niger (ATCC 6275), Aspergillus versicolor (ATCC 11730), Trichoderma viride (IAM 5061) and Penicillium funiculosum (ATCC 36839). The essential oil showed activity against bacteria P. aeruginosa, followed by M flavus, L. monocytigenes and E. coli, and all investigated fungal species.
PB  - Natural Products Inc, Westerville
T2  - Natural Product Communications
T1  - Composition and Antimicrobial Activity of Seseli globiferum Essential Oil
VL  - 6
IS  - 8
SP  - 1163
EP  - 1166
DO  - 10.1177/1934578X1100600831
ER  - 

@article{
author = "Janaćković, Peđa T. and Soković, Marina and Vujisić, Ljubodrag V. and Vajs, Vlatka and Vučković, Ivan and Krivosej, Zoran and Marin, Petar D.",
year = "2011",
abstract = "The essential oil from aerial parts of Seseli globiferum Vis. obtained by hydrodistillation with Clevenger-type apparatus was analyzed by GC-MS. Twenty-eight compounds were identified, representing 99.4% of the total oil. The main components of the oil were sabinene (38.0%), alpha-pinene (21.2%) and beta-phellandrene (13.5%). The microbial growth inhibitory properties of the isolated essential oil were determined using the broth microdilution method against seven bacterial species: Salmonella typhimurium (ATCC 13311), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Enterobacter cloacae (clinical isolates), Bacillus cereus (clinical isolates), Staphylococcus aureus (ATCC 25923), Staphylococcus epidermidis (ATCC 12228), Micrococcus flaw's (ATCC 10240) and three fungal species: Aspergillus niger (ATCC 6275), Aspergillus versicolor (ATCC 11730), Trichoderma viride (IAM 5061) and Penicillium funiculosum (ATCC 36839). The essential oil showed activity against bacteria P. aeruginosa, followed by M flavus, L. monocytigenes and E. coli, and all investigated fungal species.",
publisher = "Natural Products Inc, Westerville",
journal = "Natural Product Communications",
title = "Composition and Antimicrobial Activity of Seseli globiferum Essential Oil",
volume = "6",
number = "8",
pages = "1163-1166",
doi = "10.1177/1934578X1100600831"
}

Janaćković, P. T., Soković, M., Vujisić, L. V., Vajs, V., Vučković, I., Krivosej, Z.,& Marin, P. D.. (2011). Composition and Antimicrobial Activity of Seseli globiferum Essential Oil. in Natural Product Communications
Natural Products Inc, Westerville., 6(8), 1163-1166.
https://doi.org/10.1177/1934578X1100600831

Janaćković PT, Soković M, Vujisić LV, Vajs V, Vučković I, Krivosej Z, Marin PD. Composition and Antimicrobial Activity of Seseli globiferum Essential Oil. in Natural Product Communications. 2011;6(8):1163-1166.
doi:10.1177/1934578X1100600831 .

Janaćković, Peđa T., Soković, Marina, Vujisić, Ljubodrag V., Vajs, Vlatka, Vučković, Ivan, Krivosej, Zoran, Marin, Petar D., "Composition and Antimicrobial Activity of Seseli globiferum Essential Oil" in Natural Product Communications, 6, no. 8 (2011):1163-1166,
https://doi.org/10.1177/1934578X1100600831 . .