@article{
author = "Đurović, Dijana and Milisavljevic, Branka and Nedovic-Vukovic, Mirjana and Potkonjak, Branislav and Spasić, Snežana and Vrvić, Miroslav",
year = "2017",
abstract = "The concentrations of zinc (Zn), iron (Fe) and copper (Cu) in both human milk and infant formula were determined using a new sample preparation method, by inductively coupled plasma -optical emission spectometry (ICP-OES) and flame atomic absorption spectrometry (FAAS). Human milk samples were diluted in ultrapure water. The infant formula of powder samples (suitable for an infant 1-6 months of age) and standard reference material (SRM-1849) were analyzed in parallel. The results have shown that FAAS method was more sensitive for Fe determination in human milk while ICP-OES was more sensitive for both Zn and Cu detection. The limit of quantification for both Zn and Cu was 5 mu g L-1 and 10 mu g L-1 for Fe and the recovery for Zn, Fe and Cu was ranged from 90% to 94%, 97% to 103% and 90% to 102%, respectively. Mean concentrations of Zn, Fe, and Cu in human milk samples were 5.35, 0.47 and 0.83 mg L-1, respectively while these values in infant formula were ranged from 3.52-4.75 mg L-1, 3.37-4.56 mg L-1 and 0.28-0.41 mg L-1, respectively. Despite the sample complexity, the proposed method using dilution of milk samples with water was simple, rapid, effective and accurate. ICP-OES was a better method for Zn determination while FAAS was a better method for Fe determination. In the case of Cu both methods were comparable.",
publisher = "Slovenian Chemical Society",
journal = "Acta Chimica Slovenica",
title = "Determination of Microelements in Human Milk and Infant Formula Without Digestion by ICP-OES",
volume = "64",
number = "2",
pages = "276-282",
doi = "10.17344/acsi.2016.2582"
}