TY  - JOUR
AU  - Aćimović, Milica
AU  - Pezo, Lato
AU  - Čabarkapa, Ivana
AU  - Trudić, Anika
AU  - Stanković Jeremić, Jovana
AU  - Varga, Ana
AU  - Lončar, Biljana
AU  - Šovljanski, Olja
AU  - Tešević, Vele
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5587
AB  - This study aimed to investigate the chemical composition of steam distillate essential oil and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore, their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cis-thujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration (MBC/MFC) were 14.20 and 28.4 μL mL−1, respectively). MIC and MBC values of other tested bacteria ranged between 28.40 and 227.25 μL mL−1 while for Candida albicans MIC/MFC ranged from 28.40/56.81 to 56.81–113.63 μL mL−1. Antibiotic susceptibility patterns for the analyzed eight respiratory-associated microorganisms showed an intermediate level of resistance to commonly used antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an alternative to conventional antibiotic therapy.
PB  - MDPI AG
T2  - Processes
T1  - Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity
VL  - 10
IS  - 8
SP  - 1608
DO  - 10.3390/pr10081608
ER  - 

@article{
author = "Aćimović, Milica and Pezo, Lato and Čabarkapa, Ivana and Trudić, Anika and Stanković Jeremić, Jovana and Varga, Ana and Lončar, Biljana and Šovljanski, Olja and Tešević, Vele",
year = "2022",
abstract = "This study aimed to investigate the chemical composition of steam distillate essential oil and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore, their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cis-thujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration (MBC/MFC) were 14.20 and 28.4 μL mL−1, respectively). MIC and MBC values of other tested bacteria ranged between 28.40 and 227.25 μL mL−1 while for Candida albicans MIC/MFC ranged from 28.40/56.81 to 56.81–113.63 μL mL−1. Antibiotic susceptibility patterns for the analyzed eight respiratory-associated microorganisms showed an intermediate level of resistance to commonly used antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an alternative to conventional antibiotic therapy.",
publisher = "MDPI AG",
journal = "Processes",
title = "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity",
volume = "10",
number = "8",
pages = "1608",
doi = "10.3390/pr10081608"
}

Aćimović, M., Pezo, L., Čabarkapa, I., Trudić, A., Stanković Jeremić, J., Varga, A., Lončar, B., Šovljanski, O.,& Tešević, V.. (2022). Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes
MDPI AG., 10(8), 1608.
https://doi.org/10.3390/pr10081608

Aćimović M, Pezo L, Čabarkapa I, Trudić A, Stanković Jeremić J, Varga A, Lončar B, Šovljanski O, Tešević V. Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes. 2022;10(8):1608.
doi:10.3390/pr10081608 .

Aćimović, Milica, Pezo, Lato, Čabarkapa, Ivana, Trudić, Anika, Stanković Jeremić, Jovana, Varga, Ana, Lončar, Biljana, Šovljanski, Olja, Tešević, Vele, "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity" in Processes, 10, no. 8 (2022):1608,
https://doi.org/10.3390/pr10081608 . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Šeregelj, Vanja
AU  - Simić, Katarina
AU  - Varga, Ana
AU  - Pezo, Lato
AU  - Vulić, Jelena
AU  - Čabarkapa, Ivana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5353
AB  - Essential oil (EO) obtained by hydrodistillation in a Clevenger-type apparatus from aerial parts of Nepeta cataria L. var. citriodora (Becker), cultivated in Serbia was subjected to gas chromatography-mass spectroscopy (GC-MS) to determine the composition. Furthermore, N. cataria var. citriodora essential oil was
tested to determine its antimicrobial, antioxidant, antihyperglycemic and anti-inflammatory activities in vitro.
The antimicrobial activity was tested by broth microdilution method against 16 bacterial strains from American Type Culture Collection (ATCC). Four common tests for measuring in vitro antioxidant activity were used: 2, 2-diphenyl-1-picrylhydrazyl assay (DPPH), reducing power (RP), 2,2-azino-bis-3-ethylbenzothiazoline-
6-sulfonic acid (ABTS) and β-carotene bleaching assay (BCB). Antihyperglycemic activity was examined by using α-glucosidase inhibitory potential (AHgA), while anti-inflammatory activity (AIA) was determined by protein denaturation bioassay, using egg albumin. In total, 36 compounds were isolated and detected by GC-MS technique in N. cataria var. citriodora EO. The EO is mainly comprised of oxygenated monoterpenes (93.1%), and the main compounds were two monoterpenoid alcohols, nerol (38.5%) and geraniol (24.9%), followed by two aliphatic aldehyde, geranial (14.6%) and neral (11.0%). Antimicrobial activity of this EO shows growth inhibition of all tested bacteria strains, and exhibited good antioxidant, antihyperglycemic and anti-inflammatory activities. The EO obtained from N. cataria var. citriodora grown in Serbia shows valuable biological activity, indicating its potential for use as a supplement in everyday diet and as a natural preservative in food industry.
PB  - Lublin : Uniwersytetu  Przyrodniczego Lublin
T2  - Acta Scientiarum Polonorum Hortorum Cultus
T1  - Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities
VL  - 21
IS  - 4
SP  - 67
EP  - 74
DO  - 10.24326/asphc.2022.4.7
ER  - 

@article{
author = "Aćimović, Milica and Šeregelj, Vanja and Simić, Katarina and Varga, Ana and Pezo, Lato and Vulić, Jelena and Čabarkapa, Ivana",
year = "2022",
abstract = "Essential oil (EO) obtained by hydrodistillation in a Clevenger-type apparatus from aerial parts of Nepeta cataria L. var. citriodora (Becker), cultivated in Serbia was subjected to gas chromatography-mass spectroscopy (GC-MS) to determine the composition. Furthermore, N. cataria var. citriodora essential oil was
tested to determine its antimicrobial, antioxidant, antihyperglycemic and anti-inflammatory activities in vitro.
The antimicrobial activity was tested by broth microdilution method against 16 bacterial strains from American Type Culture Collection (ATCC). Four common tests for measuring in vitro antioxidant activity were used: 2, 2-diphenyl-1-picrylhydrazyl assay (DPPH), reducing power (RP), 2,2-azino-bis-3-ethylbenzothiazoline-
6-sulfonic acid (ABTS) and β-carotene bleaching assay (BCB). Antihyperglycemic activity was examined by using α-glucosidase inhibitory potential (AHgA), while anti-inflammatory activity (AIA) was determined by protein denaturation bioassay, using egg albumin. In total, 36 compounds were isolated and detected by GC-MS technique in N. cataria var. citriodora EO. The EO is mainly comprised of oxygenated monoterpenes (93.1%), and the main compounds were two monoterpenoid alcohols, nerol (38.5%) and geraniol (24.9%), followed by two aliphatic aldehyde, geranial (14.6%) and neral (11.0%). Antimicrobial activity of this EO shows growth inhibition of all tested bacteria strains, and exhibited good antioxidant, antihyperglycemic and anti-inflammatory activities. The EO obtained from N. cataria var. citriodora grown in Serbia shows valuable biological activity, indicating its potential for use as a supplement in everyday diet and as a natural preservative in food industry.",
publisher = "Lublin : Uniwersytetu  Przyrodniczego Lublin",
journal = "Acta Scientiarum Polonorum Hortorum Cultus",
title = "Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities",
volume = "21",
number = "4",
pages = "67-74",
doi = "10.24326/asphc.2022.4.7"
}

Aćimović, M., Šeregelj, V., Simić, K., Varga, A., Pezo, L., Vulić, J.,& Čabarkapa, I.. (2022). Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities. in Acta Scientiarum Polonorum Hortorum Cultus
Lublin : Uniwersytetu  Przyrodniczego Lublin., 21(4), 67-74.
https://doi.org/10.24326/asphc.2022.4.7

Aćimović M, Šeregelj V, Simić K, Varga A, Pezo L, Vulić J, Čabarkapa I. Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities. in Acta Scientiarum Polonorum Hortorum Cultus. 2022;21(4):67-74.
doi:10.24326/asphc.2022.4.7 .

Aćimović, Milica, Šeregelj, Vanja, Simić, Katarina, Varga, Ana, Pezo, Lato, Vulić, Jelena, Čabarkapa, Ivana, "Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities" in Acta Scientiarum Polonorum Hortorum Cultus, 21, no. 4 (2022):67-74,
https://doi.org/10.24326/asphc.2022.4.7 . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Varga, Ana
AU  - Cvetković, Mirjana
AU  - Lato, Pezo
AU  - Lončar, Biljana
AU  - Ignjatov, Maja
AU  - Zeremski, Tijana
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4692
AB  - Hyssop (Hyssopus officinalis L., Lamiaceae) is a perennial shrub or subshrub violet-blue flowers in verticillasters and spicy taste with a pungent flavour. Besides being used as a culinary herb for flavouring and food preservation, this plant is also an ornamental, bee attracting plant and a traditional remedy for respiratory diseases and digestive disturbances. Hyssop is an essential oil-bearing plant, and its essential oil (Hyssopi aetheroleum) is used in the pharmaceutical, perfume and cosmetics industries as well as in aromatherapy. The objective of this study was to determine the chemical composition of essential oil of hyssop CV. "Domaći ljubičasti", grown in Serbia, and investigate its antimicrobial activity against 16 bacteria, mainly pathogens in the food industry. A total of 61 compounds were detected in the hyssop essential oil. The bicyclic monoterpene ketones CIS-pinocamphone (43.8%) and trans-pinocamphone (18.3%) were the most abundant, comprising 62.1%, followed by b-pinene (6.3%) and pinocarvone (6.1%). Hyssop essential oil expressed antibacterial activity against: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Proteus hauseri, Listeria monocytogenes, Rhodococcus equi, Listeria ivanovii, Salmonella Enteritidis, Enterococcus faecalis, Listeria innocua and Bacillus spizizenii. Hyssop essential oil did not express antibacterial activity against Pseudomonas aeruginosa, Salmonella Typhimurium, Klebsiella aerogenes and Staphylococcus epidermidis. Results of this study show that hyssop essential oil has potential for using as natural supplement for control of foodborne diseases of microbiological origin, as well as flavor compositions (herbaceous, camphor-like odour with warm and spicy undernotes), especially for meat products, sauces, soups and seasonings.
AB  - Miloduh (Hyssopus officinalis L., Lamiaceae) je višegodišnji žbun ili polužbun aromatičnog i oštrog mirisa zbog čega se koristi kao začinska biljka. Takođe je i ukrasna i medonosna biljka, ali i tradicionalni lek za bolesti organa za disanje i kod poremećaja varenja. Miloduh je cenjena eterično-aromatična biljka, a etarsko ulje se koristi u farmaceutskoj, parfimerijskoj i kozmetičkoj industriji kao i aromaterapiji. Cilj ovog istraživanja je bio da se determiniše hemijski sastav etarskog ulja miloduha kultivara „Domaći ljubičasti“ gajenog u Srbiji, i da se ispita antimikrobna aktivnost na 16 bakterija, uglavnom patogena u prehrambenoj industriji. Ukupno 61 komponenta je detektovana u etarskom ulju, pri čemu su monoterpenski ketoni cis-pinokamfon (43.8%) i trans-pinokamfon (18.3%) bili najzastupljeniji, čineći 62.1%, a potom slede β-pinen i pinokarvon. Etarsko ulje miloduha je ispoljilo antibakterijsku aktivnost na: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Proteus hauseri, Listeria monocytogenes, Rhodococcus equi, Listeria ivanovii, Salmonella Enteritidis, Enterococcus faecalis, Listeria innocua i Bacillus spizizenii, dok nije delovalo na Pseudomonas aeruginosa, Salmonella Typhimurium, Klebsiella aerogenes i Staphylococcus epidermidis.
PB  - Belgrade : Centre for Evaluation in Education and Science
T2  - Ratarstvo i Povrtarstvo
T1  - Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity
T1  - Hemijski sastav etarskog ulja miloduha kultivara  'Domaći ljubičasti' i ocena antimikrobne aktivnosti
VL  - 58
IS  - 1
SP  - 23
EP  - 30
DO  - 10.5937/ratpov58-31751
ER  - 

@article{
author = "Aćimović, Milica and Varga, Ana and Cvetković, Mirjana and Lato, Pezo and Lončar, Biljana and Ignjatov, Maja and Zeremski, Tijana",
year = "2021",
abstract = "Hyssop (Hyssopus officinalis L., Lamiaceae) is a perennial shrub or subshrub violet-blue flowers in verticillasters and spicy taste with a pungent flavour. Besides being used as a culinary herb for flavouring and food preservation, this plant is also an ornamental, bee attracting plant and a traditional remedy for respiratory diseases and digestive disturbances. Hyssop is an essential oil-bearing plant, and its essential oil (Hyssopi aetheroleum) is used in the pharmaceutical, perfume and cosmetics industries as well as in aromatherapy. The objective of this study was to determine the chemical composition of essential oil of hyssop CV. "Domaći ljubičasti", grown in Serbia, and investigate its antimicrobial activity against 16 bacteria, mainly pathogens in the food industry. A total of 61 compounds were detected in the hyssop essential oil. The bicyclic monoterpene ketones CIS-pinocamphone (43.8%) and trans-pinocamphone (18.3%) were the most abundant, comprising 62.1%, followed by b-pinene (6.3%) and pinocarvone (6.1%). Hyssop essential oil expressed antibacterial activity against: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Proteus hauseri, Listeria monocytogenes, Rhodococcus equi, Listeria ivanovii, Salmonella Enteritidis, Enterococcus faecalis, Listeria innocua and Bacillus spizizenii. Hyssop essential oil did not express antibacterial activity against Pseudomonas aeruginosa, Salmonella Typhimurium, Klebsiella aerogenes and Staphylococcus epidermidis. Results of this study show that hyssop essential oil has potential for using as natural supplement for control of foodborne diseases of microbiological origin, as well as flavor compositions (herbaceous, camphor-like odour with warm and spicy undernotes), especially for meat products, sauces, soups and seasonings., Miloduh (Hyssopus officinalis L., Lamiaceae) je višegodišnji žbun ili polužbun aromatičnog i oštrog mirisa zbog čega se koristi kao začinska biljka. Takođe je i ukrasna i medonosna biljka, ali i tradicionalni lek za bolesti organa za disanje i kod poremećaja varenja. Miloduh je cenjena eterično-aromatična biljka, a etarsko ulje se koristi u farmaceutskoj, parfimerijskoj i kozmetičkoj industriji kao i aromaterapiji. Cilj ovog istraživanja je bio da se determiniše hemijski sastav etarskog ulja miloduha kultivara „Domaći ljubičasti“ gajenog u Srbiji, i da se ispita antimikrobna aktivnost na 16 bakterija, uglavnom patogena u prehrambenoj industriji. Ukupno 61 komponenta je detektovana u etarskom ulju, pri čemu su monoterpenski ketoni cis-pinokamfon (43.8%) i trans-pinokamfon (18.3%) bili najzastupljeniji, čineći 62.1%, a potom slede β-pinen i pinokarvon. Etarsko ulje miloduha je ispoljilo antibakterijsku aktivnost na: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Proteus hauseri, Listeria monocytogenes, Rhodococcus equi, Listeria ivanovii, Salmonella Enteritidis, Enterococcus faecalis, Listeria innocua i Bacillus spizizenii, dok nije delovalo na Pseudomonas aeruginosa, Salmonella Typhimurium, Klebsiella aerogenes i Staphylococcus epidermidis.",
publisher = "Belgrade : Centre for Evaluation in Education and Science",
journal = "Ratarstvo i Povrtarstvo",
title = "Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity, Hemijski sastav etarskog ulja miloduha kultivara  'Domaći ljubičasti' i ocena antimikrobne aktivnosti",
volume = "58",
number = "1",
pages = "23-30",
doi = "10.5937/ratpov58-31751"
}

Aćimović, M., Varga, A., Cvetković, M., Lato, P., Lončar, B., Ignjatov, M.,& Zeremski, T.. (2021). Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity. in Ratarstvo i Povrtarstvo
Belgrade : Centre for Evaluation in Education and Science., 58(1), 23-30.
https://doi.org/10.5937/ratpov58-31751

Aćimović M, Varga A, Cvetković M, Lato P, Lončar B, Ignjatov M, Zeremski T. Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity. in Ratarstvo i Povrtarstvo. 2021;58(1):23-30.
doi:10.5937/ratpov58-31751 .

Aćimović, Milica, Varga, Ana, Cvetković, Mirjana, Lato, Pezo, Lončar, Biljana, Ignjatov, Maja, Zeremski, Tijana, "Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity" in Ratarstvo i Povrtarstvo, 58, no. 1 (2021):23-30,
https://doi.org/10.5937/ratpov58-31751 . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Varga, Ana
AU  - Cvetković, Mirjana
AU  - Stanković, Jovana
AU  - Čabarkapa, Ivana
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2381
AB  - The aim of the present study was to clarify the chemical composition of essential oil from seeds of Angelica (Angelica sylvestris) plants growing wild in Serbia. In the essential oil, a total of 27 compounds were detected, among which 22 compounds were identified (comprising 97.9% of all compounds), while five were unidentified (comprising 2.1%). The main components were limonene (66.6%) and alpha-pinene (19.0%), followed by camphene (1.9%), alpha-phellandrene (1.6%), bornyl acetate (1.6%), and trans-caryophyllene (1.0%), while all other compounds were present in amounts of less than 1.0%. The antibacterial effect of the essential oil of wild Angelica seeds was tested against two pathogenic bacteria that cause food poisoning, viz., Staphylococcus aureus and Escherichia coli. According to the obtained results, S. aureus was more sensitive to A. sylvestris seed oil than E. coli. The minimal inhibitory concentrations were 28.40 mu L/mL and 56.81 mu L/mL, respectively, confirming a good antibacterial activity potential of the essential oil against E. coli and S. aureus, and indicating possibilities for its application in the food and pharmaceutical industries.
AB  - Cilj ovog istraživanja je bio da se utvrdi hemijski sastav etarskog ulja divlje anđelike (Angelica sylvestris)
dobijenog hidrodestilacijom semena samoniklih biljaka iz Srbije. U etarskom ulju utvrđeno je 27 komponenti (koje čine 97.9%), među kojima je pet nedeterminisanih komponenti (koje čine 2.1%). Dominantne komponente su limonen (66.6%) i α-pinen (19.0%), a potom slede kamfen (1.9%), α-felandren (1.6%), bornil
acetat (1.6%) i trans-kariofilen (1.0%), dok su ostale komponente bile prisutne sa manje od 1.0%. Takođe, cilj ispitivanja je bio i antibakterijski efekat ovog ulja na dve patogene bakterije koje su uzročnici trovanja hranom: Staphylococcus aureus i Escherichia coli. Na osnovu rezultata, utvrđeno je da je S. aureus značajno osetljiviji na uticaj etarskog ulja semena A. sylvestris u poređenju sa E. coli. Minimalna inhibitorna koncentracija je bili 28.40 µL/mL i 56.81 µL/mL, što potvrđuje dobru antibakterijsku aktivnost na obe bakterije, kao i na mogućnost njegove primene u prehrambenoj i farmaceutskoj industriji.
PB  - University of Belgrade
T2  - Botanica Serbica
T1  - Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds
T1  - Hemijska karakterizacija i antibakterijska aktivnost
etarskog ulja semena divlje anđelike
VL  - 42
IS  - 2
SP  - 217
EP  - 221
DO  - 10.5281/zenodo.1468310
ER  - 

@article{
author = "Aćimović, Milica and Varga, Ana and Cvetković, Mirjana and Stanković, Jovana and Čabarkapa, Ivana",
year = "2018",
abstract = "The aim of the present study was to clarify the chemical composition of essential oil from seeds of Angelica (Angelica sylvestris) plants growing wild in Serbia. In the essential oil, a total of 27 compounds were detected, among which 22 compounds were identified (comprising 97.9% of all compounds), while five were unidentified (comprising 2.1%). The main components were limonene (66.6%) and alpha-pinene (19.0%), followed by camphene (1.9%), alpha-phellandrene (1.6%), bornyl acetate (1.6%), and trans-caryophyllene (1.0%), while all other compounds were present in amounts of less than 1.0%. The antibacterial effect of the essential oil of wild Angelica seeds was tested against two pathogenic bacteria that cause food poisoning, viz., Staphylococcus aureus and Escherichia coli. According to the obtained results, S. aureus was more sensitive to A. sylvestris seed oil than E. coli. The minimal inhibitory concentrations were 28.40 mu L/mL and 56.81 mu L/mL, respectively, confirming a good antibacterial activity potential of the essential oil against E. coli and S. aureus, and indicating possibilities for its application in the food and pharmaceutical industries., Cilj ovog istraživanja je bio da se utvrdi hemijski sastav etarskog ulja divlje anđelike (Angelica sylvestris)
dobijenog hidrodestilacijom semena samoniklih biljaka iz Srbije. U etarskom ulju utvrđeno je 27 komponenti (koje čine 97.9%), među kojima je pet nedeterminisanih komponenti (koje čine 2.1%). Dominantne komponente su limonen (66.6%) i α-pinen (19.0%), a potom slede kamfen (1.9%), α-felandren (1.6%), bornil
acetat (1.6%) i trans-kariofilen (1.0%), dok su ostale komponente bile prisutne sa manje od 1.0%. Takođe, cilj ispitivanja je bio i antibakterijski efekat ovog ulja na dve patogene bakterije koje su uzročnici trovanja hranom: Staphylococcus aureus i Escherichia coli. Na osnovu rezultata, utvrđeno je da je S. aureus značajno osetljiviji na uticaj etarskog ulja semena A. sylvestris u poređenju sa E. coli. Minimalna inhibitorna koncentracija je bili 28.40 µL/mL i 56.81 µL/mL, što potvrđuje dobru antibakterijsku aktivnost na obe bakterije, kao i na mogućnost njegove primene u prehrambenoj i farmaceutskoj industriji.",
publisher = "University of Belgrade",
journal = "Botanica Serbica",
title = "Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds, Hemijska karakterizacija i antibakterijska aktivnost
etarskog ulja semena divlje anđelike",
volume = "42",
number = "2",
pages = "217-221",
doi = "10.5281/zenodo.1468310"
}

Aćimović, M., Varga, A., Cvetković, M., Stanković, J.,& Čabarkapa, I.. (2018). Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds. in Botanica Serbica
University of Belgrade., 42(2), 217-221.
https://doi.org/10.5281/zenodo.1468310

Aćimović M, Varga A, Cvetković M, Stanković J, Čabarkapa I. Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds. in Botanica Serbica. 2018;42(2):217-221.
doi:10.5281/zenodo.1468310 .

Aćimović, Milica, Varga, Ana, Cvetković, Mirjana, Stanković, Jovana, Čabarkapa, Ivana, "Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds" in Botanica Serbica, 42, no. 2 (2018):217-221,
https://doi.org/10.5281/zenodo.1468310 . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Pavlovic, Snezana D.
AU  - Varga, Ana
AU  - Filipović, Vladimir M.
AU  - Cvetković, Mirjana
AU  - Stanković, Jovana
AU  - Čabarkapa, Ivana
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2192
AB  - Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.
PB  - Natural Product Incorporation
T2  - Natural Product Communications
T1  - Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil
VL  - 12
IS  - 2
SP  - 205
EP  - 206
UR  - https://hdl.handle.net/21.15107/rcub_cer_2192
ER  - 

@article{
author = "Aćimović, Milica and Pavlovic, Snezana D. and Varga, Ana and Filipović, Vladimir M. and Cvetković, Mirjana and Stanković, Jovana and Čabarkapa, Ivana",
year = "2017",
abstract = "Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.",
publisher = "Natural Product Incorporation",
journal = "Natural Product Communications",
title = "Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil",
volume = "12",
number = "2",
pages = "205-206",
url = "https://hdl.handle.net/21.15107/rcub_cer_2192"
}

Aćimović, M., Pavlovic, S. D., Varga, A., Filipović, V. M., Cvetković, M., Stanković, J.,& Čabarkapa, I.. (2017). Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil. in Natural Product Communications
Natural Product Incorporation., 12(2), 205-206.
https://hdl.handle.net/21.15107/rcub_cer_2192

Aćimović M, Pavlovic SD, Varga A, Filipović VM, Cvetković M, Stanković J, Čabarkapa I. Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil. in Natural Product Communications. 2017;12(2):205-206.
https://hdl.handle.net/21.15107/rcub_cer_2192 .

Aćimović, Milica, Pavlovic, Snezana D., Varga, Ana, Filipović, Vladimir M., Cvetković, Mirjana, Stanković, Jovana, Čabarkapa, Ivana, "Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil" in Natural Product Communications, 12, no. 2 (2017):205-206,
https://hdl.handle.net/21.15107/rcub_cer_2192 .