Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil
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AuthorsAćimović, Milica G.
Pavlovic, Snezana D.
Varga, Ana O.
Filipovic, Vladimir M.
Cabarkapa, Ivana S.
Article (Published version)
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Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.
Keywords:Angelica / Staphylococcus aureus / Escherichia coli / MIC / MBC
Source:Natural Product Communications, 2017, 12, 2, 205-206
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