TY  - JOUR
AU  - Konstantinović, Sandra S.
AU  - Zlatkovic, Milica Z.
AU  - Ciric, Jovan T.
AU  - Ilić, Slavica B.
AU  - Gojgić-Cvijović, Gordana
AU  - Veljković, Vlada B.
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2102
AB  - In the present work, four derivatives of salicylaldehyde (salicylaldehyde-hydrazone, phenylhydrazone, semicarbazone and thiosemicarbazone) were synthesized using both conventional (95% ethanol) and green (crude glycerol from biodiesel production) solvents. The obtained compounds were identified by elemental microanalysis, as well as FTIR, UV/Vis and H-1-NMR spectroscopic methods. Yields of 93-98% of the compounds in crude glycerol were achieved within 10-25 min. The derivatives of salicylaldehyde and crude glycerol were used as a nitrogen and carbon source, respectively, in the medium for antibiotic (hexaene H-85 and azalomycine B) production by Streptomyces hygroscopicus CH-7. The highest concentrations of hexaene H-85 and azalomycine B were achieved in the medium containing salicylaldehyde-thiosemicarbazone (198 and 69 mu g/cm(3), respectively). Derivatives of salicylaldehyde also impacted the strain morphology. In the media with salicylaldehyde- phenylhydrazone and salicylaldehyde-thiosemicarbazone, S. hygroscopicus CH-7 grew like large dispersive pellets with long twisted filaments that produced the highest yield of the antibiotics.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7
VL  - 71
IS  - 6
SP  - 487
EP  - 494
DO  - 10.2298/HEMIND170124011K
ER  - 

@article{
author = "Konstantinović, Sandra S. and Zlatkovic, Milica Z. and Ciric, Jovan T. and Ilić, Slavica B. and Gojgić-Cvijović, Gordana and Veljković, Vlada B.",
year = "2017",
abstract = "In the present work, four derivatives of salicylaldehyde (salicylaldehyde-hydrazone, phenylhydrazone, semicarbazone and thiosemicarbazone) were synthesized using both conventional (95% ethanol) and green (crude glycerol from biodiesel production) solvents. The obtained compounds were identified by elemental microanalysis, as well as FTIR, UV/Vis and H-1-NMR spectroscopic methods. Yields of 93-98% of the compounds in crude glycerol were achieved within 10-25 min. The derivatives of salicylaldehyde and crude glycerol were used as a nitrogen and carbon source, respectively, in the medium for antibiotic (hexaene H-85 and azalomycine B) production by Streptomyces hygroscopicus CH-7. The highest concentrations of hexaene H-85 and azalomycine B were achieved in the medium containing salicylaldehyde-thiosemicarbazone (198 and 69 mu g/cm(3), respectively). Derivatives of salicylaldehyde also impacted the strain morphology. In the media with salicylaldehyde- phenylhydrazone and salicylaldehyde-thiosemicarbazone, S. hygroscopicus CH-7 grew like large dispersive pellets with long twisted filaments that produced the highest yield of the antibiotics.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7",
volume = "71",
number = "6",
pages = "487-494",
doi = "10.2298/HEMIND170124011K"
}

Konstantinović, S. S., Zlatkovic, M. Z., Ciric, J. T., Ilić, S. B., Gojgić-Cvijović, G.,& Veljković, V. B.. (2017). The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7. in Hemijska industrija
Association of Chemical Engineers of Serbia., 71(6), 487-494.
https://doi.org/10.2298/HEMIND170124011K

Konstantinović SS, Zlatkovic MZ, Ciric JT, Ilić SB, Gojgić-Cvijović G, Veljković VB. The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7. in Hemijska industrija. 2017;71(6):487-494.
doi:10.2298/HEMIND170124011K .

Konstantinović, Sandra S., Zlatkovic, Milica Z., Ciric, Jovan T., Ilić, Slavica B., Gojgić-Cvijović, Gordana, Veljković, Vlada B., "The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7" in Hemijska industrija, 71, no. 6 (2017):487-494,
https://doi.org/10.2298/HEMIND170124011K . .