Čabarkapa, Ivana

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orcid::0000-0003-2215-4281
  • Čabarkapa, Ivana (9)

Author's Bibliography

Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools

Aćimović, Milica; Cvetković, Mirjana; Stanković Jeremić, Jovana; Pezo, Lato; Varga, Ana; Čabarkapa, Ivana; Kiprovski, Biljana

(Wiley, 2022)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Cvetković, Mirjana
AU  - Stanković Jeremić, Jovana
AU  - Pezo, Lato
AU  - Varga, Ana
AU  - Čabarkapa, Ivana
AU  - Kiprovski, Biljana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5406
AB  - Salvia sclarea L. or clary sage is cultivated worldwide in temperate and sub-tropical climates, as an ornamental and essential oil (EO) bearing plant. EO is obtained from fresh spikes in full flowering stage and is recognized as an important commercial product for food, beverage and cosmetic industries. This study investigated the EO composition of S. sclarea grown in Serbia (Southeast Europe) obtained by two different methods, steam (SD) and hydrodistillation (HD). GC-MS analysis identified oxygenated monoterpenes as the main class of compounds for all EOs (between 81.8% and 88.2% depending on the distillation process). The most abundant oxygenated monoterpenes were linalyl acetate and linalool. In addition, in vitro antimicrobial (modified resazurin microtitre-plate assay) and antioxidant activities (DPPH• assay) and total polyphenol content of obtained EOs were also evaluated. According to the assay used for the evaluation of the antibacterial activity, Gram-negative bacteria were more sensitive to S. sclarea EO in comparison to Gram-positive bacteria. EOs exhibited low antioxidant capacity, below 3% neutralized DPPH• radicals, reaching up to approximately 400 µg AAE mL-1. This study also investigated a possibility for predicting retention indices (RIs) of compounds isolated from EOs. In total, 78 experimentally obtained RIs were applied to construct the prediction model. The quantitative structure-chromatographic retention relationship (QSRR) model was used to anticipate the experimentally obtained RIs. Five molecular descriptors were selected by factor analysis and genetic algorithm to predict RIs. The obtained accuracy of the QSRR model reached r2 =.912, which showed that these models might be applied for predicting retention indices.
PB  - Wiley
T2  - Flavour and Fragrance Journal
T1  - Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools
VL  - 37
IS  - 1
SP  - 20
EP  - 32
DO  - 10.1002/ffj.3684
ER  - 
@article{
author = "Aćimović, Milica and Cvetković, Mirjana and Stanković Jeremić, Jovana and Pezo, Lato and Varga, Ana and Čabarkapa, Ivana and Kiprovski, Biljana",
year = "2022",
abstract = "Salvia sclarea L. or clary sage is cultivated worldwide in temperate and sub-tropical climates, as an ornamental and essential oil (EO) bearing plant. EO is obtained from fresh spikes in full flowering stage and is recognized as an important commercial product for food, beverage and cosmetic industries. This study investigated the EO composition of S. sclarea grown in Serbia (Southeast Europe) obtained by two different methods, steam (SD) and hydrodistillation (HD). GC-MS analysis identified oxygenated monoterpenes as the main class of compounds for all EOs (between 81.8% and 88.2% depending on the distillation process). The most abundant oxygenated monoterpenes were linalyl acetate and linalool. In addition, in vitro antimicrobial (modified resazurin microtitre-plate assay) and antioxidant activities (DPPH• assay) and total polyphenol content of obtained EOs were also evaluated. According to the assay used for the evaluation of the antibacterial activity, Gram-negative bacteria were more sensitive to S. sclarea EO in comparison to Gram-positive bacteria. EOs exhibited low antioxidant capacity, below 3% neutralized DPPH• radicals, reaching up to approximately 400 µg AAE mL-1. This study also investigated a possibility for predicting retention indices (RIs) of compounds isolated from EOs. In total, 78 experimentally obtained RIs were applied to construct the prediction model. The quantitative structure-chromatographic retention relationship (QSRR) model was used to anticipate the experimentally obtained RIs. Five molecular descriptors were selected by factor analysis and genetic algorithm to predict RIs. The obtained accuracy of the QSRR model reached r2 =.912, which showed that these models might be applied for predicting retention indices.",
publisher = "Wiley",
journal = "Flavour and Fragrance Journal",
title = "Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools",
volume = "37",
number = "1",
pages = "20-32",
doi = "10.1002/ffj.3684"
}
Aćimović, M., Cvetković, M., Stanković Jeremić, J., Pezo, L., Varga, A., Čabarkapa, I.,& Kiprovski, B.. (2022). Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools. in Flavour and Fragrance Journal
Wiley., 37(1), 20-32.
https://doi.org/10.1002/ffj.3684
Aćimović M, Cvetković M, Stanković Jeremić J, Pezo L, Varga A, Čabarkapa I, Kiprovski B. Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools. in Flavour and Fragrance Journal. 2022;37(1):20-32.
doi:10.1002/ffj.3684 .
Aćimović, Milica, Cvetković, Mirjana, Stanković Jeremić, Jovana, Pezo, Lato, Varga, Ana, Čabarkapa, Ivana, Kiprovski, Biljana, "Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools" in Flavour and Fragrance Journal, 37, no. 1 (2022):20-32,
https://doi.org/10.1002/ffj.3684 . .
3
24
2
22

Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity

Aćimović, Milica; Pezo, Lato; Čabarkapa, Ivana; Trudić, Anika; Stanković Jeremić, Jovana; Varga, Ana; Lončar, Biljana; Šovljanski, Olja; Tešević, Vele

(MDPI AG, 2022)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Pezo, Lato
AU  - Čabarkapa, Ivana
AU  - Trudić, Anika
AU  - Stanković Jeremić, Jovana
AU  - Varga, Ana
AU  - Lončar, Biljana
AU  - Šovljanski, Olja
AU  - Tešević, Vele
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5587
AB  - This study aimed to investigate the chemical composition of steam distillate essential oil and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore, their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cis-thujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration (MBC/MFC) were 14.20 and 28.4 μL mL−1, respectively). MIC and MBC values of other tested bacteria ranged between 28.40 and 227.25 μL mL−1 while for Candida albicans MIC/MFC ranged from 28.40/56.81 to 56.81–113.63 μL mL−1. Antibiotic susceptibility patterns for the analyzed eight respiratory-associated microorganisms showed an intermediate level of resistance to commonly used antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an alternative to conventional antibiotic therapy.
PB  - MDPI AG
T2  - Processes
T1  - Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity
VL  - 10
IS  - 8
SP  - 1608
DO  - 10.3390/pr10081608
ER  - 
@article{
author = "Aćimović, Milica and Pezo, Lato and Čabarkapa, Ivana and Trudić, Anika and Stanković Jeremić, Jovana and Varga, Ana and Lončar, Biljana and Šovljanski, Olja and Tešević, Vele",
year = "2022",
abstract = "This study aimed to investigate the chemical composition of steam distillate essential oil and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore, their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cis-thujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration (MBC/MFC) were 14.20 and 28.4 μL mL−1, respectively). MIC and MBC values of other tested bacteria ranged between 28.40 and 227.25 μL mL−1 while for Candida albicans MIC/MFC ranged from 28.40/56.81 to 56.81–113.63 μL mL−1. Antibiotic susceptibility patterns for the analyzed eight respiratory-associated microorganisms showed an intermediate level of resistance to commonly used antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an alternative to conventional antibiotic therapy.",
publisher = "MDPI AG",
journal = "Processes",
title = "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity",
volume = "10",
number = "8",
pages = "1608",
doi = "10.3390/pr10081608"
}
Aćimović, M., Pezo, L., Čabarkapa, I., Trudić, A., Stanković Jeremić, J., Varga, A., Lončar, B., Šovljanski, O.,& Tešević, V.. (2022). Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes
MDPI AG., 10(8), 1608.
https://doi.org/10.3390/pr10081608
Aćimović M, Pezo L, Čabarkapa I, Trudić A, Stanković Jeremić J, Varga A, Lončar B, Šovljanski O, Tešević V. Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes. 2022;10(8):1608.
doi:10.3390/pr10081608 .
Aćimović, Milica, Pezo, Lato, Čabarkapa, Ivana, Trudić, Anika, Stanković Jeremić, Jovana, Varga, Ana, Lončar, Biljana, Šovljanski, Olja, Tešević, Vele, "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity" in Processes, 10, no. 8 (2022):1608,
https://doi.org/10.3390/pr10081608 . .
5
5

Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities

Aćimović, Milica; Šeregelj, Vanja; Simić, Katarina; Varga, Ana; Pezo, Lato; Vulić, Jelena; Čabarkapa, Ivana

(Lublin : Uniwersytetu Przyrodniczego Lublin, 2022)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Šeregelj, Vanja
AU  - Simić, Katarina
AU  - Varga, Ana
AU  - Pezo, Lato
AU  - Vulić, Jelena
AU  - Čabarkapa, Ivana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5353
AB  - Essential oil (EO) obtained by hydrodistillation in a Clevenger-type apparatus from aerial parts of Nepeta cataria L. var. citriodora (Becker), cultivated in Serbia was subjected to gas chromatography-mass spectroscopy (GC-MS) to determine the composition. Furthermore, N. cataria var. citriodora essential oil was
tested to determine its antimicrobial, antioxidant, antihyperglycemic and anti-inflammatory activities in vitro.
The antimicrobial activity was tested by broth microdilution method against 16 bacterial strains from American Type Culture Collection (ATCC). Four common tests for measuring in vitro antioxidant activity were used: 2, 2-diphenyl-1-picrylhydrazyl assay (DPPH), reducing power (RP), 2,2-azino-bis-3-ethylbenzothiazoline-
6-sulfonic acid (ABTS) and β-carotene bleaching assay (BCB). Antihyperglycemic activity was examined by using α-glucosidase inhibitory potential (AHgA), while anti-inflammatory activity (AIA) was determined by protein denaturation bioassay, using egg albumin. In total, 36 compounds were isolated and detected by GC-MS technique in N. cataria var. citriodora EO. The EO is mainly comprised of oxygenated monoterpenes (93.1%), and the main compounds were two monoterpenoid alcohols, nerol (38.5%) and geraniol (24.9%), followed by two aliphatic aldehyde, geranial (14.6%) and neral (11.0%). Antimicrobial activity of this EO shows growth inhibition of all tested bacteria strains, and exhibited good antioxidant, antihyperglycemic and anti-inflammatory activities. The EO obtained from N. cataria var. citriodora grown in Serbia shows valuable biological activity, indicating its potential for use as a supplement in everyday diet and as a natural preservative in food industry.
PB  - Lublin : Uniwersytetu  Przyrodniczego Lublin
T2  - Acta Scientiarum Polonorum Hortorum Cultus
T1  - Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities
VL  - 21
IS  - 4
SP  - 67
EP  - 74
DO  - 10.24326/asphc.2022.4.7
ER  - 
@article{
author = "Aćimović, Milica and Šeregelj, Vanja and Simić, Katarina and Varga, Ana and Pezo, Lato and Vulić, Jelena and Čabarkapa, Ivana",
year = "2022",
abstract = "Essential oil (EO) obtained by hydrodistillation in a Clevenger-type apparatus from aerial parts of Nepeta cataria L. var. citriodora (Becker), cultivated in Serbia was subjected to gas chromatography-mass spectroscopy (GC-MS) to determine the composition. Furthermore, N. cataria var. citriodora essential oil was
tested to determine its antimicrobial, antioxidant, antihyperglycemic and anti-inflammatory activities in vitro.
The antimicrobial activity was tested by broth microdilution method against 16 bacterial strains from American Type Culture Collection (ATCC). Four common tests for measuring in vitro antioxidant activity were used: 2, 2-diphenyl-1-picrylhydrazyl assay (DPPH), reducing power (RP), 2,2-azino-bis-3-ethylbenzothiazoline-
6-sulfonic acid (ABTS) and β-carotene bleaching assay (BCB). Antihyperglycemic activity was examined by using α-glucosidase inhibitory potential (AHgA), while anti-inflammatory activity (AIA) was determined by protein denaturation bioassay, using egg albumin. In total, 36 compounds were isolated and detected by GC-MS technique in N. cataria var. citriodora EO. The EO is mainly comprised of oxygenated monoterpenes (93.1%), and the main compounds were two monoterpenoid alcohols, nerol (38.5%) and geraniol (24.9%), followed by two aliphatic aldehyde, geranial (14.6%) and neral (11.0%). Antimicrobial activity of this EO shows growth inhibition of all tested bacteria strains, and exhibited good antioxidant, antihyperglycemic and anti-inflammatory activities. The EO obtained from N. cataria var. citriodora grown in Serbia shows valuable biological activity, indicating its potential for use as a supplement in everyday diet and as a natural preservative in food industry.",
publisher = "Lublin : Uniwersytetu  Przyrodniczego Lublin",
journal = "Acta Scientiarum Polonorum Hortorum Cultus",
title = "Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities",
volume = "21",
number = "4",
pages = "67-74",
doi = "10.24326/asphc.2022.4.7"
}
Aćimović, M., Šeregelj, V., Simić, K., Varga, A., Pezo, L., Vulić, J.,& Čabarkapa, I.. (2022). Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities. in Acta Scientiarum Polonorum Hortorum Cultus
Lublin : Uniwersytetu  Przyrodniczego Lublin., 21(4), 67-74.
https://doi.org/10.24326/asphc.2022.4.7
Aćimović M, Šeregelj V, Simić K, Varga A, Pezo L, Vulić J, Čabarkapa I. Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities. in Acta Scientiarum Polonorum Hortorum Cultus. 2022;21(4):67-74.
doi:10.24326/asphc.2022.4.7 .
Aćimović, Milica, Šeregelj, Vanja, Simić, Katarina, Varga, Ana, Pezo, Lato, Vulić, Jelena, Čabarkapa, Ivana, "Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities" in Acta Scientiarum Polonorum Hortorum Cultus, 21, no. 4 (2022):67-74,
https://doi.org/10.24326/asphc.2022.4.7 . .
3
1

Essential oil quality of chamomile grown in Province of Vojvodina

Aćimović, Milica; Stanković Jeremić, Jovana; Simić, Katarina; Ivanović, Stefan; Ljujić, Jovana; Čabarkapa, Ivana; Radojčin, Milivoj; Todosijević, Marina; Cvetković, Mirjana

(Novi Sad: Poljoprivredni fakultet, 2021)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Stanković Jeremić, Jovana
AU  - Simić, Katarina
AU  - Ivanović, Stefan
AU  - Ljujić, Jovana
AU  - Čabarkapa, Ivana
AU  - Radojčin, Milivoj
AU  - Todosijević, Marina
AU  - Cvetković, Mirjana
PY  - 2021
UR  - http://letopisnaucnihradova.rs/wp-content/uploads/2021/09/Essential_oil_quality_of_chamomile_grown_in_Province_of_Vojvodina-Acimovic_et_al..pdf
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5167
AB  - Chamomile (Matricaria chamomilla L., Asteraceae) is one of the most popular medicinal plants used as a herb
infusion for treating numerous ailments, including sleep disorders, anxiety, digestion and intestinal conditions
etc. Chamomile essential oil is used in a wide variety of consumer goods such as detergents, soaps, toiletries,
cosmetics, pharmaceuticals, perfumes, confectionery food products, soft drinks, distilled alcoholic beverages
(hard liquor) and as insecticide. According to the European Pharmacopoeia, there are two types of essential
oils, one rich in bisabolol oxides and the other in α-bisabolol, which are preferred for tea brewing because of
its sweet, grassy, and slightly fruity aroma. From the other side, varieties rich in chamazulene and β-farnesene
have bitter taste, and because of that they are low valuable raw material. According to the results of the
essential oil composition obtained from three different chamomile samples grown in Province of Vojvodina, it
could be concluded that domestic cultivars “Banatska” and “Tetraploidna” contains β-farnesene as dominant
compound, while the content of bisabolol oxides and α-bisabolol was lower than required standards in
European Pharmacopoeia. Because of that they could not be classified as quality raw material. The German
cultivar “Mabamille” grown in agroecological conditions of Vojvodina region, with 37.5% of α-bisabolol can be
classified as a bisabolol rich type, and as high quality row material.
AB  - Kamilica (Matricaria chamomilla L., Asteraceae) je jedna od najpopularnijih lekovitih biljaka koja se 
upotrebljava u obliku infuza (čaja) za lečenje mnogih stanja i bolesti, uključujući poremećaje sna, napetost, probleme organa za varenje itd. Etarsko ulje kamilice se koristi u mnogim granama industrije: hemijskoj (kao dodatak deterdžentima), kozmetičkoj (u sapunima, sredstvima za ličnu higijenu), farmaceutskoj, parfimerijskoj i prehrambenoj industriji (u slatkišima, alkoholnim i bezalkoholnim pićima) i kao insekticid. Prema Evropskoj Farmakopeji, postoje dva tipa etarskog ulja kamilice, prvi koji je bogat bisabolol oksidima i drugi bogat α-bisabololom. Oba tipa su poželjna u industriji čajnih napitaka zbog njihovog slatkog, osvežavajućeg ukusa blago voćne arome. Sa druge strane, varijeteti bogati hamazulenom i β-farnezenom imaju gorak ukus i zbog toga predstavljaju manje vrednu biljnu sirovinu. Na osnovu rezultata hemijskog sastava etarskog ulja tri 
različita uzorka kamilice gajene u Pokrajini Vojvodini od strane individualnih poljoprivrednih proizvođača, može se zaključiti da domaće sorte “Banatska” i “Tetraploidna” sadrže β-farnezen kao dominantnu komponentu, dok je sadržaj bisabolol oksida i α-bisabolola niži nego što zahtevaju standardi u Evropskoj Farmakopeji, zbog čega se ne mogu kategorisati kao kvalitetni biljni materijal. Nemačka sorta “Mabamille” gajena u agroekološkim uslovima pokrajine Vojvodine, sa 37,5% α-bisabolola pripada bisabolol tipu kamilice i predstavlja visoko kvalitetnu sirovinu.
PB  - Novi Sad: Poljoprivredni fakultet
T2  - Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad
T1  - Essential oil quality of chamomile grown in Province of Vojvodina
VL  - 45
IS  - 1
SP  - 1
EP  - 8
UR  - https://hdl.handle.net/21.15107/rcub_cer_5167
ER  - 
@article{
author = "Aćimović, Milica and Stanković Jeremić, Jovana and Simić, Katarina and Ivanović, Stefan and Ljujić, Jovana and Čabarkapa, Ivana and Radojčin, Milivoj and Todosijević, Marina and Cvetković, Mirjana",
year = "2021",
abstract = "Chamomile (Matricaria chamomilla L., Asteraceae) is one of the most popular medicinal plants used as a herb
infusion for treating numerous ailments, including sleep disorders, anxiety, digestion and intestinal conditions
etc. Chamomile essential oil is used in a wide variety of consumer goods such as detergents, soaps, toiletries,
cosmetics, pharmaceuticals, perfumes, confectionery food products, soft drinks, distilled alcoholic beverages
(hard liquor) and as insecticide. According to the European Pharmacopoeia, there are two types of essential
oils, one rich in bisabolol oxides and the other in α-bisabolol, which are preferred for tea brewing because of
its sweet, grassy, and slightly fruity aroma. From the other side, varieties rich in chamazulene and β-farnesene
have bitter taste, and because of that they are low valuable raw material. According to the results of the
essential oil composition obtained from three different chamomile samples grown in Province of Vojvodina, it
could be concluded that domestic cultivars “Banatska” and “Tetraploidna” contains β-farnesene as dominant
compound, while the content of bisabolol oxides and α-bisabolol was lower than required standards in
European Pharmacopoeia. Because of that they could not be classified as quality raw material. The German
cultivar “Mabamille” grown in agroecological conditions of Vojvodina region, with 37.5% of α-bisabolol can be
classified as a bisabolol rich type, and as high quality row material., Kamilica (Matricaria chamomilla L., Asteraceae) je jedna od najpopularnijih lekovitih biljaka koja se 
upotrebljava u obliku infuza (čaja) za lečenje mnogih stanja i bolesti, uključujući poremećaje sna, napetost, probleme organa za varenje itd. Etarsko ulje kamilice se koristi u mnogim granama industrije: hemijskoj (kao dodatak deterdžentima), kozmetičkoj (u sapunima, sredstvima za ličnu higijenu), farmaceutskoj, parfimerijskoj i prehrambenoj industriji (u slatkišima, alkoholnim i bezalkoholnim pićima) i kao insekticid. Prema Evropskoj Farmakopeji, postoje dva tipa etarskog ulja kamilice, prvi koji je bogat bisabolol oksidima i drugi bogat α-bisabololom. Oba tipa su poželjna u industriji čajnih napitaka zbog njihovog slatkog, osvežavajućeg ukusa blago voćne arome. Sa druge strane, varijeteti bogati hamazulenom i β-farnezenom imaju gorak ukus i zbog toga predstavljaju manje vrednu biljnu sirovinu. Na osnovu rezultata hemijskog sastava etarskog ulja tri 
različita uzorka kamilice gajene u Pokrajini Vojvodini od strane individualnih poljoprivrednih proizvođača, može se zaključiti da domaće sorte “Banatska” i “Tetraploidna” sadrže β-farnezen kao dominantnu komponentu, dok je sadržaj bisabolol oksida i α-bisabolola niži nego što zahtevaju standardi u Evropskoj Farmakopeji, zbog čega se ne mogu kategorisati kao kvalitetni biljni materijal. Nemačka sorta “Mabamille” gajena u agroekološkim uslovima pokrajine Vojvodine, sa 37,5% α-bisabolola pripada bisabolol tipu kamilice i predstavlja visoko kvalitetnu sirovinu.",
publisher = "Novi Sad: Poljoprivredni fakultet",
journal = "Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad",
title = "Essential oil quality of chamomile grown in Province of Vojvodina",
volume = "45",
number = "1",
pages = "1-8",
url = "https://hdl.handle.net/21.15107/rcub_cer_5167"
}
Aćimović, M., Stanković Jeremić, J., Simić, K., Ivanović, S., Ljujić, J., Čabarkapa, I., Radojčin, M., Todosijević, M.,& Cvetković, M.. (2021). Essential oil quality of chamomile grown in Province of Vojvodina. in Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad
Novi Sad: Poljoprivredni fakultet., 45(1), 1-8.
https://hdl.handle.net/21.15107/rcub_cer_5167
Aćimović M, Stanković Jeremić J, Simić K, Ivanović S, Ljujić J, Čabarkapa I, Radojčin M, Todosijević M, Cvetković M. Essential oil quality of chamomile grown in Province of Vojvodina. in Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad. 2021;45(1):1-8.
https://hdl.handle.net/21.15107/rcub_cer_5167 .
Aćimović, Milica, Stanković Jeremić, Jovana, Simić, Katarina, Ivanović, Stefan, Ljujić, Jovana, Čabarkapa, Ivana, Radojčin, Milivoj, Todosijević, Marina, Cvetković, Mirjana, "Essential oil quality of chamomile grown in Province of Vojvodina" in Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad, 45, no. 1 (2021):1-8,
https://hdl.handle.net/21.15107/rcub_cer_5167 .

Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices

Aćimović, Milica G.; Pezo, Lato L.; Cvetković, Mirjana; Stanković, Jovana; Čabarkapa, Ivana

(Belgrade : Serbian Chemical Society, 2021)

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Pezo, Lato L.
AU  - Cvetković, Mirjana
AU  - Stanković, Jovana
AU  - Čabarkapa, Ivana
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4710
AB  - The aim of this study was the prediction model of retention indices of compounds from the aboveground parts of Achillea clypeolata Sibth. & Sm. essential oil, obtained by hydrodistillation and analysed by GC-MS. The quantitative structure-retention relationship analysis was applied in order to anticipate the retention time of the obtained compounds. The selection of the seven molecular descriptors was done by a genetic algorithm. The chosen descriptors were uncorrelated and were used to construct an artificial neural network. A total of 40 experimentally obtained retention indices was used to build this prediction model. The coefficient of determination for the training, testing and validation cycles were: 0.950, 0.825 and 1.000, respectively, indicating that this model could be used for prediction of retention indices for A.
AB  - Циљ ове студије био је израда модела за предвиђања ретенционог времена хемијских једињења из есенцијалног уља надземних делова биљке Achillea clypeolata Sibth. & Sm., добијеног хидродистилацијом и анализираног GC–MS техником. Квантитативна анализа хемијске структуре и предвиђања ретенционог времена (quantitative structure– retention relationship – QSRR) је примењена да би се предвидело време задржавања хемијских једињења добијених коришћењем GC–MS анализе. Избор седам молекулских дескриптора извршен је коришћењем факторске анализе и генетског алгоритма. Примећено је да изабрани дескриптори нису били у међусобној корелацији, па су коришћени као улазни подаци при изградњи вештачке неуронске мреже. У изградњи модела предвиђања ретенционих времена коришћено је укупно 40 експериментално добијених ретенционих времена. Коефицијент детерминације током циклуса припреме, тестирања и i валидације достигао је вредности 0,950; 0,825 и 1,000, редом, што указује на то да се овај модел може користити за предвиђање ретенционих времена хемијских једињења добијених из есенцијалног уља A. clypeolata
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices
T1  - Hemijski sastav etarskog ulja Achillea clypeolata Sibth. & Sm. И QSRR model za predviđanje retencionog vremena
VL  - 86
IS  - 4
SP  - 355
EP  - 366
DO  - 10.2298/JSC200524008A
ER  - 
@article{
author = "Aćimović, Milica G. and Pezo, Lato L. and Cvetković, Mirjana and Stanković, Jovana and Čabarkapa, Ivana",
year = "2021",
abstract = "The aim of this study was the prediction model of retention indices of compounds from the aboveground parts of Achillea clypeolata Sibth. & Sm. essential oil, obtained by hydrodistillation and analysed by GC-MS. The quantitative structure-retention relationship analysis was applied in order to anticipate the retention time of the obtained compounds. The selection of the seven molecular descriptors was done by a genetic algorithm. The chosen descriptors were uncorrelated and were used to construct an artificial neural network. A total of 40 experimentally obtained retention indices was used to build this prediction model. The coefficient of determination for the training, testing and validation cycles were: 0.950, 0.825 and 1.000, respectively, indicating that this model could be used for prediction of retention indices for A., Циљ ове студије био је израда модела за предвиђања ретенционог времена хемијских једињења из есенцијалног уља надземних делова биљке Achillea clypeolata Sibth. & Sm., добијеног хидродистилацијом и анализираног GC–MS техником. Квантитативна анализа хемијске структуре и предвиђања ретенционог времена (quantitative structure– retention relationship – QSRR) је примењена да би се предвидело време задржавања хемијских једињења добијених коришћењем GC–MS анализе. Избор седам молекулских дескриптора извршен је коришћењем факторске анализе и генетског алгоритма. Примећено је да изабрани дескриптори нису били у међусобној корелацији, па су коришћени као улазни подаци при изградњи вештачке неуронске мреже. У изградњи модела предвиђања ретенционих времена коришћено је укупно 40 експериментално добијених ретенционих времена. Коефицијент детерминације током циклуса припреме, тестирања и i валидације достигао је вредности 0,950; 0,825 и 1,000, редом, што указује на то да се овај модел може користити за предвиђање ретенционих времена хемијских једињења добијених из есенцијалног уља A. clypeolata",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices, Hemijski sastav etarskog ulja Achillea clypeolata Sibth. & Sm. И QSRR model za predviđanje retencionog vremena",
volume = "86",
number = "4",
pages = "355-366",
doi = "10.2298/JSC200524008A"
}
Aćimović, M. G., Pezo, L. L., Cvetković, M., Stanković, J.,& Čabarkapa, I.. (2021). Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 86(4), 355-366.
https://doi.org/10.2298/JSC200524008A
Aćimović MG, Pezo LL, Cvetković M, Stanković J, Čabarkapa I. Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices. in Journal of the Serbian Chemical Society. 2021;86(4):355-366.
doi:10.2298/JSC200524008A .
Aćimović, Milica G., Pezo, Lato L., Cvetković, Mirjana, Stanković, Jovana, Čabarkapa, Ivana, "Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices" in Journal of the Serbian Chemical Society, 86, no. 4 (2021):355-366,
https://doi.org/10.2298/JSC200524008A . .
2
1

Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia

Aćimović, Milica; Zorić, Miroslav; Zheljazkov, Valtcho; Pezo, Lato; Čabarkapa, Ivana; Stanković Jeremić, Jovana; Cvetković, Mirjana

(MDPI, 2020)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Zorić, Miroslav
AU  - Zheljazkov, Valtcho
AU  - Pezo, Lato
AU  - Čabarkapa, Ivana
AU  - Stanković Jeremić, Jovana
AU  - Cvetković, Mirjana
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3952
AB  - The objective of this study was to evaluate wild growing Satureja kitaibelii, Thymus serpyllum,
Origanum vulgare, Achillea millefolium and Achillea clypeolata with respect to their essential oil (EO)
content, composition and antimicrobial activity. The five species were collected at Mt. Rtanj and the
village of Sesalac, Eastern Serbia. The main EO constituents of Lamiaceae plants were p-cymene
(24.4%), geraniol (63.4%) and germacrene D (21.5%) in Satureja kitaibelii, Thymus serpyllum and
Origanum vulgare ssp. vulgare, respectively. A. millefolium EO had multiple constituents with major
ones being camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-cineole (5.6%),
while the main EO constituents of A. clypeolata were 1,8-cineole (45.1%) and camphor (18.2%).
Antimicrobial testing of the EO showed that Staphylococcus aureus (Gram-positive) was more sensitive
to all of the tested EOs than Escherichia coli (Gram-negative). S. kitaibelii EO showed the highest
antimicrobial activity against both tested bacterial strains. This is the first study to characterize
the EO composition and antimicrobial activity of these five medicinal species from Eastern Serbia
in comparison with comprehensive literature data. The results can be utilized by the perfumery,
cosmetics, food and pharmaceutical industries, but also for healing purposes in self-medication.
PB  - MDPI
T2  - Molecules
T1  - Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia
VL  - 25
IS  - 22
SP  - 5482
DO  - 10.3390/molecules25225482
ER  - 
@article{
author = "Aćimović, Milica and Zorić, Miroslav and Zheljazkov, Valtcho and Pezo, Lato and Čabarkapa, Ivana and Stanković Jeremić, Jovana and Cvetković, Mirjana",
year = "2020",
abstract = "The objective of this study was to evaluate wild growing Satureja kitaibelii, Thymus serpyllum,
Origanum vulgare, Achillea millefolium and Achillea clypeolata with respect to their essential oil (EO)
content, composition and antimicrobial activity. The five species were collected at Mt. Rtanj and the
village of Sesalac, Eastern Serbia. The main EO constituents of Lamiaceae plants were p-cymene
(24.4%), geraniol (63.4%) and germacrene D (21.5%) in Satureja kitaibelii, Thymus serpyllum and
Origanum vulgare ssp. vulgare, respectively. A. millefolium EO had multiple constituents with major
ones being camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-cineole (5.6%),
while the main EO constituents of A. clypeolata were 1,8-cineole (45.1%) and camphor (18.2%).
Antimicrobial testing of the EO showed that Staphylococcus aureus (Gram-positive) was more sensitive
to all of the tested EOs than Escherichia coli (Gram-negative). S. kitaibelii EO showed the highest
antimicrobial activity against both tested bacterial strains. This is the first study to characterize
the EO composition and antimicrobial activity of these five medicinal species from Eastern Serbia
in comparison with comprehensive literature data. The results can be utilized by the perfumery,
cosmetics, food and pharmaceutical industries, but also for healing purposes in self-medication.",
publisher = "MDPI",
journal = "Molecules",
title = "Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia",
volume = "25",
number = "22",
pages = "5482",
doi = "10.3390/molecules25225482"
}
Aćimović, M., Zorić, M., Zheljazkov, V., Pezo, L., Čabarkapa, I., Stanković Jeremić, J.,& Cvetković, M.. (2020). Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia. in Molecules
MDPI., 25(22), 5482.
https://doi.org/10.3390/molecules25225482
Aćimović M, Zorić M, Zheljazkov V, Pezo L, Čabarkapa I, Stanković Jeremić J, Cvetković M. Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia. in Molecules. 2020;25(22):5482.
doi:10.3390/molecules25225482 .
Aćimović, Milica, Zorić, Miroslav, Zheljazkov, Valtcho, Pezo, Lato, Čabarkapa, Ivana, Stanković Jeremić, Jovana, Cvetković, Mirjana, "Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia" in Molecules, 25, no. 22 (2020):5482,
https://doi.org/10.3390/molecules25225482 . .
17
6

QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil

Aćimović, Milica; Pezo, Lato; Stanković, Jovana; Cvetković, Mirjana; Rat, Milica; Čabarkapa, Ivana; Tešević, Vele

(Taylor & Francis, 2020)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Pezo, Lato
AU  - Stanković, Jovana
AU  - Cvetković, Mirjana
AU  - Rat, Milica
AU  - Čabarkapa, Ivana
AU  - Tešević, Vele
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3951
AB  - A total of 26 experimentally obtained retention indices on a logarithmic scale (log RI) from
Thymus serpyllum essential oil were used to build a robust predictive model. The selected descriptors were
used as inputs of an artificial neural network model to build a predictive quantitative structure-retention time
relationship model. The coefficient of determination for the training cycle was 0.977, indicating that this model
could be used for the prediction of retention indices for T. serpyllum essential oil compounds. These 26
compounds comprise about 99.8 % of the total oil, but among them only 6 compounds had the average relative
concentration over 1 percent: geraniol (63.4 %), nerol (or cis-geraniol) (18.9 %), geranyl acetate (4.7 %), transcaryophyllene (4.6 %), β-bisabolene (2.0 %) and geranial (1.2 %). According to these results, it can be concluded
that T. serpyllum from village Sesalac (Serbia) belongs to geraniol chemotype, in total 82.3 % in both, trans and
cis forms (63.4 % and 18.9 %, respectively).
PB  - Taylor & Francis
T2  - Essential Oil Bearing Plants
T1  - QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil
VL  - 23
IS  - 3
SP  - 464
EP  - 473
DO  - 10.1080/0972060X.2020.1790428
ER  - 
@article{
author = "Aćimović, Milica and Pezo, Lato and Stanković, Jovana and Cvetković, Mirjana and Rat, Milica and Čabarkapa, Ivana and Tešević, Vele",
year = "2020",
abstract = "A total of 26 experimentally obtained retention indices on a logarithmic scale (log RI) from
Thymus serpyllum essential oil were used to build a robust predictive model. The selected descriptors were
used as inputs of an artificial neural network model to build a predictive quantitative structure-retention time
relationship model. The coefficient of determination for the training cycle was 0.977, indicating that this model
could be used for the prediction of retention indices for T. serpyllum essential oil compounds. These 26
compounds comprise about 99.8 % of the total oil, but among them only 6 compounds had the average relative
concentration over 1 percent: geraniol (63.4 %), nerol (or cis-geraniol) (18.9 %), geranyl acetate (4.7 %), transcaryophyllene (4.6 %), β-bisabolene (2.0 %) and geranial (1.2 %). According to these results, it can be concluded
that T. serpyllum from village Sesalac (Serbia) belongs to geraniol chemotype, in total 82.3 % in both, trans and
cis forms (63.4 % and 18.9 %, respectively).",
publisher = "Taylor & Francis",
journal = "Essential Oil Bearing Plants",
title = "QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil",
volume = "23",
number = "3",
pages = "464-473",
doi = "10.1080/0972060X.2020.1790428"
}
Aćimović, M., Pezo, L., Stanković, J., Cvetković, M., Rat, M., Čabarkapa, I.,& Tešević, V.. (2020). QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil. in Essential Oil Bearing Plants
Taylor & Francis., 23(3), 464-473.
https://doi.org/10.1080/0972060X.2020.1790428
Aćimović M, Pezo L, Stanković J, Cvetković M, Rat M, Čabarkapa I, Tešević V. QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil. in Essential Oil Bearing Plants. 2020;23(3):464-473.
doi:10.1080/0972060X.2020.1790428 .
Aćimović, Milica, Pezo, Lato, Stanković, Jovana, Cvetković, Mirjana, Rat, Milica, Čabarkapa, Ivana, Tešević, Vele, "QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil" in Essential Oil Bearing Plants, 23, no. 3 (2020):464-473,
https://doi.org/10.1080/0972060X.2020.1790428 . .
7
3
8

Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds

Aćimović, Milica; Varga, Ana; Cvetković, Mirjana; Stanković, Jovana; Čabarkapa, Ivana

(University of Belgrade, 2018)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Varga, Ana
AU  - Cvetković, Mirjana
AU  - Stanković, Jovana
AU  - Čabarkapa, Ivana
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2381
AB  - The aim of the present study was to clarify the chemical composition of essential oil from seeds of Angelica (Angelica sylvestris) plants growing wild in Serbia. In the essential oil, a total of 27 compounds were detected, among which 22 compounds were identified (comprising 97.9% of all compounds), while five were unidentified (comprising 2.1%). The main components were limonene (66.6%) and alpha-pinene (19.0%), followed by camphene (1.9%), alpha-phellandrene (1.6%), bornyl acetate (1.6%), and trans-caryophyllene (1.0%), while all other compounds were present in amounts of less than 1.0%. The antibacterial effect of the essential oil of wild Angelica seeds was tested against two pathogenic bacteria that cause food poisoning, viz., Staphylococcus aureus and Escherichia coli. According to the obtained results, S. aureus was more sensitive to A. sylvestris seed oil than E. coli. The minimal inhibitory concentrations were 28.40 mu L/mL and 56.81 mu L/mL, respectively, confirming a good antibacterial activity potential of the essential oil against E. coli and S. aureus, and indicating possibilities for its application in the food and pharmaceutical industries.
AB  - Cilj ovog istraživanja je bio da se utvrdi hemijski sastav etarskog ulja divlje anđelike (Angelica sylvestris)
dobijenog hidrodestilacijom semena samoniklih biljaka iz Srbije. U etarskom ulju utvrđeno je 27 komponenti (koje čine 97.9%), među kojima je pet nedeterminisanih komponenti (koje čine 2.1%). Dominantne komponente su limonen (66.6%) i α-pinen (19.0%), a potom slede kamfen (1.9%), α-felandren (1.6%), bornil
acetat (1.6%) i trans-kariofilen (1.0%), dok su ostale komponente bile prisutne sa manje od 1.0%. Takođe, cilj ispitivanja je bio i antibakterijski efekat ovog ulja na dve patogene bakterije koje su uzročnici trovanja hranom: Staphylococcus aureus i Escherichia coli. Na osnovu rezultata, utvrđeno je da je S. aureus značajno osetljiviji na uticaj etarskog ulja semena A. sylvestris u poređenju sa E. coli. Minimalna inhibitorna koncentracija je bili 28.40 µL/mL i 56.81 µL/mL, što potvrđuje dobru antibakterijsku aktivnost na obe bakterije, kao i na mogućnost njegove primene u prehrambenoj i farmaceutskoj industriji.
PB  - University of Belgrade
T2  - Botanica Serbica
T1  - Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds
T1  - Hemijska karakterizacija i antibakterijska aktivnost
etarskog ulja semena divlje anđelike
VL  - 42
IS  - 2
SP  - 217
EP  - 221
DO  - 10.5281/zenodo.1468310
ER  - 
@article{
author = "Aćimović, Milica and Varga, Ana and Cvetković, Mirjana and Stanković, Jovana and Čabarkapa, Ivana",
year = "2018",
abstract = "The aim of the present study was to clarify the chemical composition of essential oil from seeds of Angelica (Angelica sylvestris) plants growing wild in Serbia. In the essential oil, a total of 27 compounds were detected, among which 22 compounds were identified (comprising 97.9% of all compounds), while five were unidentified (comprising 2.1%). The main components were limonene (66.6%) and alpha-pinene (19.0%), followed by camphene (1.9%), alpha-phellandrene (1.6%), bornyl acetate (1.6%), and trans-caryophyllene (1.0%), while all other compounds were present in amounts of less than 1.0%. The antibacterial effect of the essential oil of wild Angelica seeds was tested against two pathogenic bacteria that cause food poisoning, viz., Staphylococcus aureus and Escherichia coli. According to the obtained results, S. aureus was more sensitive to A. sylvestris seed oil than E. coli. The minimal inhibitory concentrations were 28.40 mu L/mL and 56.81 mu L/mL, respectively, confirming a good antibacterial activity potential of the essential oil against E. coli and S. aureus, and indicating possibilities for its application in the food and pharmaceutical industries., Cilj ovog istraživanja je bio da se utvrdi hemijski sastav etarskog ulja divlje anđelike (Angelica sylvestris)
dobijenog hidrodestilacijom semena samoniklih biljaka iz Srbije. U etarskom ulju utvrđeno je 27 komponenti (koje čine 97.9%), među kojima je pet nedeterminisanih komponenti (koje čine 2.1%). Dominantne komponente su limonen (66.6%) i α-pinen (19.0%), a potom slede kamfen (1.9%), α-felandren (1.6%), bornil
acetat (1.6%) i trans-kariofilen (1.0%), dok su ostale komponente bile prisutne sa manje od 1.0%. Takođe, cilj ispitivanja je bio i antibakterijski efekat ovog ulja na dve patogene bakterije koje su uzročnici trovanja hranom: Staphylococcus aureus i Escherichia coli. Na osnovu rezultata, utvrđeno je da je S. aureus značajno osetljiviji na uticaj etarskog ulja semena A. sylvestris u poređenju sa E. coli. Minimalna inhibitorna koncentracija je bili 28.40 µL/mL i 56.81 µL/mL, što potvrđuje dobru antibakterijsku aktivnost na obe bakterije, kao i na mogućnost njegove primene u prehrambenoj i farmaceutskoj industriji.",
publisher = "University of Belgrade",
journal = "Botanica Serbica",
title = "Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds, Hemijska karakterizacija i antibakterijska aktivnost
etarskog ulja semena divlje anđelike",
volume = "42",
number = "2",
pages = "217-221",
doi = "10.5281/zenodo.1468310"
}
Aćimović, M., Varga, A., Cvetković, M., Stanković, J.,& Čabarkapa, I.. (2018). Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds. in Botanica Serbica
University of Belgrade., 42(2), 217-221.
https://doi.org/10.5281/zenodo.1468310
Aćimović M, Varga A, Cvetković M, Stanković J, Čabarkapa I. Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds. in Botanica Serbica. 2018;42(2):217-221.
doi:10.5281/zenodo.1468310 .
Aćimović, Milica, Varga, Ana, Cvetković, Mirjana, Stanković, Jovana, Čabarkapa, Ivana, "Chemical characterisation and antibacterial activity of the essential oil of wild Angelica seeds" in Botanica Serbica, 42, no. 2 (2018):217-221,
https://doi.org/10.5281/zenodo.1468310 . .
6
1
5

Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil

Aćimović, Milica; Pavlovic, Snezana D.; Varga, Ana; Filipović, Vladimir M.; Cvetković, Mirjana; Stanković, Jovana; Čabarkapa, Ivana

(Natural Product Incorporation, 2017)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Pavlovic, Snezana D.
AU  - Varga, Ana
AU  - Filipović, Vladimir M.
AU  - Cvetković, Mirjana
AU  - Stanković, Jovana
AU  - Čabarkapa, Ivana
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2192
AB  - Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.
PB  - Natural Product Incorporation
T2  - Natural Product Communications
T1  - Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil
VL  - 12
IS  - 2
SP  - 205
EP  - 206
UR  - https://hdl.handle.net/21.15107/rcub_cer_2192
ER  - 
@article{
author = "Aćimović, Milica and Pavlovic, Snezana D. and Varga, Ana and Filipović, Vladimir M. and Cvetković, Mirjana and Stanković, Jovana and Čabarkapa, Ivana",
year = "2017",
abstract = "Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.",
publisher = "Natural Product Incorporation",
journal = "Natural Product Communications",
title = "Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil",
volume = "12",
number = "2",
pages = "205-206",
url = "https://hdl.handle.net/21.15107/rcub_cer_2192"
}
Aćimović, M., Pavlovic, S. D., Varga, A., Filipović, V. M., Cvetković, M., Stanković, J.,& Čabarkapa, I.. (2017). Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil. in Natural Product Communications
Natural Product Incorporation., 12(2), 205-206.
https://hdl.handle.net/21.15107/rcub_cer_2192
Aćimović M, Pavlovic SD, Varga A, Filipović VM, Cvetković M, Stanković J, Čabarkapa I. Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil. in Natural Product Communications. 2017;12(2):205-206.
https://hdl.handle.net/21.15107/rcub_cer_2192 .
Aćimović, Milica, Pavlovic, Snezana D., Varga, Ana, Filipović, Vladimir M., Cvetković, Mirjana, Stanković, Jovana, Čabarkapa, Ivana, "Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil" in Natural Product Communications, 12, no. 2 (2017):205-206,
https://hdl.handle.net/21.15107/rcub_cer_2192 .
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