Impact of carboxymethylcellulose on morphology and antibiotic production by Streptomyces hygroscopicus
Само за регистроване кориснике
2008
Аутори
Ilić, Slavica B.Konstantinović, Sandra S.
Veljković, Vlada B.
Savić, D.S.
Lazić, M. L.
Gojgić-Cvijović, Gordana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
A chemically defined media consisting of carboxymethylcellulose (CMC) was developed to maximize the production of antibiotics, hexaene H-85 and azalomycine, by Streptomyces hygroscopicus CH-7. The production of antibiotics by filamentous organisms is often dependent on the morphology and size distribution of the pellet population within the culture. By adding the polymer to the fermentation medium, the growth was changed from a single large glob to small reproducible pellets, and wall growth was diminished to a minimum. Maximum concentrations of hexaene H-85 (146.7 mg/dm3) and azalomycine (188.6 mg/dm3) were reached at 3.0% and 1.0% (w/v) CMC, respectively.
Извор:
Current Microbiology, 2008, 57, 1, 8-11
DOI: 10.1007/s00284-008-9143-7
ISSN: 0343-8651
PubMed: 18379844
WoS: 000256080100002
Scopus: 2-s2.0-44049087688
Институција/група
IHTMTY - JOUR AU - Ilić, Slavica B. AU - Konstantinović, Sandra S. AU - Veljković, Vlada B. AU - Savić, D.S. AU - Lazić, M. L. AU - Gojgić-Cvijović, Gordana PY - 2008 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/479 AB - A chemically defined media consisting of carboxymethylcellulose (CMC) was developed to maximize the production of antibiotics, hexaene H-85 and azalomycine, by Streptomyces hygroscopicus CH-7. The production of antibiotics by filamentous organisms is often dependent on the morphology and size distribution of the pellet population within the culture. By adding the polymer to the fermentation medium, the growth was changed from a single large glob to small reproducible pellets, and wall growth was diminished to a minimum. Maximum concentrations of hexaene H-85 (146.7 mg/dm3) and azalomycine (188.6 mg/dm3) were reached at 3.0% and 1.0% (w/v) CMC, respectively. T2 - Current Microbiology T1 - Impact of carboxymethylcellulose on morphology and antibiotic production by Streptomyces hygroscopicus VL - 57 IS - 1 SP - 8 EP - 11 DO - 10.1007/s00284-008-9143-7 ER -
@article{ author = "Ilić, Slavica B. and Konstantinović, Sandra S. and Veljković, Vlada B. and Savić, D.S. and Lazić, M. L. and Gojgić-Cvijović, Gordana", year = "2008", abstract = "A chemically defined media consisting of carboxymethylcellulose (CMC) was developed to maximize the production of antibiotics, hexaene H-85 and azalomycine, by Streptomyces hygroscopicus CH-7. The production of antibiotics by filamentous organisms is often dependent on the morphology and size distribution of the pellet population within the culture. By adding the polymer to the fermentation medium, the growth was changed from a single large glob to small reproducible pellets, and wall growth was diminished to a minimum. Maximum concentrations of hexaene H-85 (146.7 mg/dm3) and azalomycine (188.6 mg/dm3) were reached at 3.0% and 1.0% (w/v) CMC, respectively.", journal = "Current Microbiology", title = "Impact of carboxymethylcellulose on morphology and antibiotic production by Streptomyces hygroscopicus", volume = "57", number = "1", pages = "8-11", doi = "10.1007/s00284-008-9143-7" }
Ilić, S. B., Konstantinović, S. S., Veljković, V. B., Savić, D.S., Lazić, M. L.,& Gojgić-Cvijović, G.. (2008). Impact of carboxymethylcellulose on morphology and antibiotic production by Streptomyces hygroscopicus. in Current Microbiology, 57(1), 8-11. https://doi.org/10.1007/s00284-008-9143-7
Ilić SB, Konstantinović SS, Veljković VB, Savić D, Lazić ML, Gojgić-Cvijović G. Impact of carboxymethylcellulose on morphology and antibiotic production by Streptomyces hygroscopicus. in Current Microbiology. 2008;57(1):8-11. doi:10.1007/s00284-008-9143-7 .
Ilić, Slavica B., Konstantinović, Sandra S., Veljković, Vlada B., Savić, D.S., Lazić, M. L., Gojgić-Cvijović, Gordana, "Impact of carboxymethylcellulose on morphology and antibiotic production by Streptomyces hygroscopicus" in Current Microbiology, 57, no. 1 (2008):8-11, https://doi.org/10.1007/s00284-008-9143-7 . .