Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii
Samo za registrovane korisnike
2003
Autori
Savikin-Fodulovic, KAljančić, Ivana
Vajs, Vlatka
Menkonic, N
Macura, S
Gojgić-Cvijović, Gordana
Milosavljević, Slobodan
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
As shown by quantitative 1H NMR measurements, a lipophilic extract of the aerial parts of Hypericum atomarium ssp. degenii contained a high percentage (3.1% per weight of dried plant material) of a prenylated phloroglucinol (1). Compound 1, named hyperatomarin, occurring in two tautomeric forms (1a ⇆ 1b), was isolated by bioactivity-guided preparative TLC and was identified on the basis of spectral data interpretation. This isolated phloroglucinol exhibited activity against Gram-positive (Staphyloccocus aureus and Microccocus luteus) and Gram-positive spore-forming bacteria (Bacillus subtilis and B. IP 5832).
Ključne reči:
NMR / Hypericum atomarium ssp. degenii / hyperatomarin / preparative TLC / spectral data interpretation / phloroglucinolIzvor:
Journal of Natural Products, 2003, 66, 9, 1236-1238Izdavač:
- American Chemical Society (ACS)
DOI: 10.1021/np030131o
ISSN: 0163-3864
PubMed: 14510605
WoS: 000185609400020
Scopus: 2-s2.0-0141566417
Institucija/grupa
IHTMTY - JOUR AU - Savikin-Fodulovic, K AU - Aljančić, Ivana AU - Vajs, Vlatka AU - Menkonic, N AU - Macura, S AU - Gojgić-Cvijović, Gordana AU - Milosavljević, Slobodan PY - 2003 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/4155 AB - As shown by quantitative 1H NMR measurements, a lipophilic extract of the aerial parts of Hypericum atomarium ssp. degenii contained a high percentage (3.1% per weight of dried plant material) of a prenylated phloroglucinol (1). Compound 1, named hyperatomarin, occurring in two tautomeric forms (1a ⇆ 1b), was isolated by bioactivity-guided preparative TLC and was identified on the basis of spectral data interpretation. This isolated phloroglucinol exhibited activity against Gram-positive (Staphyloccocus aureus and Microccocus luteus) and Gram-positive spore-forming bacteria (Bacillus subtilis and B. IP 5832). PB - American Chemical Society (ACS) T2 - Journal of Natural Products T1 - Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii VL - 66 IS - 9 SP - 1236 EP - 1238 DO - 10.1021/np030131o ER -
@article{ author = "Savikin-Fodulovic, K and Aljančić, Ivana and Vajs, Vlatka and Menkonic, N and Macura, S and Gojgić-Cvijović, Gordana and Milosavljević, Slobodan", year = "2003", abstract = "As shown by quantitative 1H NMR measurements, a lipophilic extract of the aerial parts of Hypericum atomarium ssp. degenii contained a high percentage (3.1% per weight of dried plant material) of a prenylated phloroglucinol (1). Compound 1, named hyperatomarin, occurring in two tautomeric forms (1a ⇆ 1b), was isolated by bioactivity-guided preparative TLC and was identified on the basis of spectral data interpretation. This isolated phloroglucinol exhibited activity against Gram-positive (Staphyloccocus aureus and Microccocus luteus) and Gram-positive spore-forming bacteria (Bacillus subtilis and B. IP 5832).", publisher = "American Chemical Society (ACS)", journal = "Journal of Natural Products", title = "Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii", volume = "66", number = "9", pages = "1236-1238", doi = "10.1021/np030131o" }
Savikin-Fodulovic, K., Aljančić, I., Vajs, V., Menkonic, N., Macura, S., Gojgić-Cvijović, G.,& Milosavljević, S.. (2003). Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii. in Journal of Natural Products American Chemical Society (ACS)., 66(9), 1236-1238. https://doi.org/10.1021/np030131o
Savikin-Fodulovic K, Aljančić I, Vajs V, Menkonic N, Macura S, Gojgić-Cvijović G, Milosavljević S. Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii. in Journal of Natural Products. 2003;66(9):1236-1238. doi:10.1021/np030131o .
Savikin-Fodulovic, K, Aljančić, Ivana, Vajs, Vlatka, Menkonic, N, Macura, S, Gojgić-Cvijović, Gordana, Milosavljević, Slobodan, "Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii" in Journal of Natural Products, 66, no. 9 (2003):1236-1238, https://doi.org/10.1021/np030131o . .