Guaianolides from two subspecies of Amphoricarpos neumayeri from Montenegro
Samo za registrovane korisnike
2004
Autori
Đorđević, IrisVajs, Vlatka
Bulatović, V.
Menkovic, N
Tešević, Vele
Macura, S
Janaćković, Peđa T.
Milosavljević, Slobodan
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Quantitative H-1 NMR measurements revealed Delta(11(13)) sesquiterpene gamma-lactones as the main constituents (greater than or equal to 1% per weight of dried plant material) in the crude extracts of the aerial parts of Amphoricarpos neumayeri ssp. neumayeri and ssp. murbeckii from mountains Orjen and Visitor (Montenegro), respectively. Preparative silica gel chromatography afforded thirteen guai-11(13)-en-12,6alpha-olides, named amphoricarpolides (1-13), with the same relative (1alphaH,4PH,5alphaH,7betaH) configuration of the basic skeleton. The common structural feature of lactones 2-13 was 3beta,15-dioxygenation pattern. The only exception was 1 (3-deoxyamphoricarpolide), containing a single oxygen substituent (15-OH). Eight of them exhibited an additional oxygen substituent, 9beta-OH (5 and 6), 2alpha-OH (8-12), or 2alpha-OAc (13). Compound 7 was epoxydated at 10alpha(14)-position, whereas the remaining lactones contained a 10(14) double bond. (C) 2004 Elsevier Ltd. All rights res...erved.
Ključne reči:
Amphoricarpos neumayeri / Asteraceae / sesquiterpene lactones / guaianolides / amphoricarpolidesIzvor:
Phytochemistry, 2004, 65, 16, 2337-2345Izdavač:
- Oxford : Pergamon-Elsevier Science Ltd
Finansiranje / projekti:
- Ministry for Science, Technologies and Development (Project 1755)
DOI: 10.1016/j.phytochem.2004.07.014
ISSN: 0031-9422
PubMed: 15381005
WoS: 000224440400005
Scopus: 2-s2.0-4544342932
Institucija/grupa
IHTMTY - JOUR AU - Đorđević, Iris AU - Vajs, Vlatka AU - Bulatović, V. AU - Menkovic, N AU - Tešević, Vele AU - Macura, S AU - Janaćković, Peđa T. AU - Milosavljević, Slobodan PY - 2004 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/4148 AB - Quantitative H-1 NMR measurements revealed Delta(11(13)) sesquiterpene gamma-lactones as the main constituents (greater than or equal to 1% per weight of dried plant material) in the crude extracts of the aerial parts of Amphoricarpos neumayeri ssp. neumayeri and ssp. murbeckii from mountains Orjen and Visitor (Montenegro), respectively. Preparative silica gel chromatography afforded thirteen guai-11(13)-en-12,6alpha-olides, named amphoricarpolides (1-13), with the same relative (1alphaH,4PH,5alphaH,7betaH) configuration of the basic skeleton. The common structural feature of lactones 2-13 was 3beta,15-dioxygenation pattern. The only exception was 1 (3-deoxyamphoricarpolide), containing a single oxygen substituent (15-OH). Eight of them exhibited an additional oxygen substituent, 9beta-OH (5 and 6), 2alpha-OH (8-12), or 2alpha-OAc (13). Compound 7 was epoxydated at 10alpha(14)-position, whereas the remaining lactones contained a 10(14) double bond. (C) 2004 Elsevier Ltd. All rights reserved. PB - Oxford : Pergamon-Elsevier Science Ltd T2 - Phytochemistry T1 - Guaianolides from two subspecies of Amphoricarpos neumayeri from Montenegro VL - 65 IS - 16 SP - 2337 EP - 2345 DO - 10.1016/j.phytochem.2004.07.014 ER -
@article{ author = "Đorđević, Iris and Vajs, Vlatka and Bulatović, V. and Menkovic, N and Tešević, Vele and Macura, S and Janaćković, Peđa T. and Milosavljević, Slobodan", year = "2004", abstract = "Quantitative H-1 NMR measurements revealed Delta(11(13)) sesquiterpene gamma-lactones as the main constituents (greater than or equal to 1% per weight of dried plant material) in the crude extracts of the aerial parts of Amphoricarpos neumayeri ssp. neumayeri and ssp. murbeckii from mountains Orjen and Visitor (Montenegro), respectively. Preparative silica gel chromatography afforded thirteen guai-11(13)-en-12,6alpha-olides, named amphoricarpolides (1-13), with the same relative (1alphaH,4PH,5alphaH,7betaH) configuration of the basic skeleton. The common structural feature of lactones 2-13 was 3beta,15-dioxygenation pattern. The only exception was 1 (3-deoxyamphoricarpolide), containing a single oxygen substituent (15-OH). Eight of them exhibited an additional oxygen substituent, 9beta-OH (5 and 6), 2alpha-OH (8-12), or 2alpha-OAc (13). Compound 7 was epoxydated at 10alpha(14)-position, whereas the remaining lactones contained a 10(14) double bond. (C) 2004 Elsevier Ltd. All rights reserved.", publisher = "Oxford : Pergamon-Elsevier Science Ltd", journal = "Phytochemistry", title = "Guaianolides from two subspecies of Amphoricarpos neumayeri from Montenegro", volume = "65", number = "16", pages = "2337-2345", doi = "10.1016/j.phytochem.2004.07.014" }
Đorđević, I., Vajs, V., Bulatović, V., Menkovic, N., Tešević, V., Macura, S., Janaćković, P. T.,& Milosavljević, S.. (2004). Guaianolides from two subspecies of Amphoricarpos neumayeri from Montenegro. in Phytochemistry Oxford : Pergamon-Elsevier Science Ltd., 65(16), 2337-2345. https://doi.org/10.1016/j.phytochem.2004.07.014
Đorđević I, Vajs V, Bulatović V, Menkovic N, Tešević V, Macura S, Janaćković PT, Milosavljević S. Guaianolides from two subspecies of Amphoricarpos neumayeri from Montenegro. in Phytochemistry. 2004;65(16):2337-2345. doi:10.1016/j.phytochem.2004.07.014 .
Đorđević, Iris, Vajs, Vlatka, Bulatović, V., Menkovic, N, Tešević, Vele, Macura, S, Janaćković, Peđa T., Milosavljević, Slobodan, "Guaianolides from two subspecies of Amphoricarpos neumayeri from Montenegro" in Phytochemistry, 65, no. 16 (2004):2337-2345, https://doi.org/10.1016/j.phytochem.2004.07.014 . .