Prikaz osnovnih podataka o dokumentu
Synthesis of 2,3-Dihydro-4-pyridones and 4-Pyridones by the Cyclization Reaction of Ester-Tethered Enaminones
dc.creator | Stojanović, Milovan | |
dc.creator | Bugarski, Slobodan | |
dc.creator | Baranac-Stojanović, Marija | |
dc.date.accessioned | 2020-12-16T00:00:49Z | |
dc.date.available | 2020-12-16T00:00:49Z | |
dc.date.issued | 2020 | |
dc.identifier.issn | 0022-3263 | |
dc.identifier.issn | 1520-6904 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/4020 | |
dc.description.abstract | 2,3-Dihydro-4-pyridone skeleton is an important building block in organic synthesis because it features several reaction sites with nucleophilic or electrophilic properties. Herein, we disclose a method for its formation by intramolecular cyclization of ester-tethered enaminones, which can easily be synthesized from readily available materials, such as amines, activated alkynes, and activated alkenes. 2,3-Dihydro-4-pyridones have been isolated in 41–90% yields. We also demonstrate the transformation of these heterocycles into another important class of compounds, 4-pyridones, by utilizing 2,3,5,6-tetrachloro-p-benzoquinone (chloranil) as an oxidizing agent. The latter products were isolated in 65–94% yields. | en |
dc.publisher | American Chemical Society (ACS) | en |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200168/RS// | |
dc.rights | restrictedAccess | |
dc.source | The Journal of Organic Chemistry | en |
dc.subject | Hydrocarbons | |
dc.subject | Aromatic compounds | |
dc.subject | Organic compounds | |
dc.subject | Amines | |
dc.subject | Cyclization | |
dc.title | Synthesis of 2,3-Dihydro-4-pyridones and 4-Pyridones by the Cyclization Reaction of Ester-Tethered Enaminones | en |
dc.type | article | en |
dc.rights.license | ARR | |
dcterms.abstract | Бугарски, Слободан; Стојановић, Милован; Баранац-Стојановић, Марија; | |
dc.citation.volume | 85 | |
dc.citation.issue | 21 | |
dc.citation.spage | 13495 | |
dc.citation.epage | 13507 | |
dc.citation.rank | M21~ | |
dc.identifier.pmid | 33092340 | |
dc.identifier.doi | 10.1021/acs.joc.0c01537 | |
dc.identifier.scopus | 2-s2.0-85095834928 | |
dc.identifier.wos | 000589941700010 | |
dc.type.version | publishedVersion |