TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor
Authorized Users Only
2020
Authors
Ognjanović, MilošStanković, Vesna
Knežević, Sara
Antić, Bratislav
Vranješ-Đurić, Sanja
Stanković, Dalibor
Article (Published version)
,
Elsevier
Metadata
Show full item recordAbstract
Herein, we proposed a novel approach and state-of-the-art technology for the improvement of the materials and
enzyme immobilization at the electrode surface and construction of impedimetric glucose biosensor. We silanized
titanium dioxide nanoparticles using (3-aminopropyl)triethoxysilane (APTES), for the preparation of crosslinked
material nanoparticles, with carboxylic graphene. The silanization of titanium dioxide nanoparticles and
an increase in electron shuttle was proven feasible when this composite was able to achieve about 30% higher
current than non-silanized material. The proposed approach was used for the modification of the printed threeelectrode
system and the development of the impedimetric glucose biosensor. The material morphology and
electrochemical characteristics were confirmed by spectroscopic and electrochemical methods. The present
combination effectively modified the electrode surface and serve as a promising basis for the construction of
Point-of-Care d...evices. Developed biosensor possesses wide operating linear range toward glucose detection from
50 μmol to 1000 μmol, with the limit of detection of 24 μmol. Finally, negligible interference effect and application
in the real sample indicate that the proposed mechanism can be successfully applied to the assessment
of glucose level in only one drop of real sample.
Keywords:
Titanium dioxide / Carboxylic graphene / APTES / Cross-linking / Impedimetric biosensorSource:
Microchemical Journal, 2020, 158, 105150-Publisher:
- Elsevier
Funding / projects:
- EUREKA project E! 13303 MED-BIO-TEST
DOI: 10.1016/j.microc.2020.105150
ISSN: 0026-265X
WoS: 000573647400007
Scopus: 2-s2.0-85086377141
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Institution/Community
IHTMTY - JOUR AU - Ognjanović, Miloš AU - Stanković, Vesna AU - Knežević, Sara AU - Antić, Bratislav AU - Vranješ-Đurić, Sanja AU - Stanković, Dalibor PY - 2020 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/3594 AB - Herein, we proposed a novel approach and state-of-the-art technology for the improvement of the materials and enzyme immobilization at the electrode surface and construction of impedimetric glucose biosensor. We silanized titanium dioxide nanoparticles using (3-aminopropyl)triethoxysilane (APTES), for the preparation of crosslinked material nanoparticles, with carboxylic graphene. The silanization of titanium dioxide nanoparticles and an increase in electron shuttle was proven feasible when this composite was able to achieve about 30% higher current than non-silanized material. The proposed approach was used for the modification of the printed threeelectrode system and the development of the impedimetric glucose biosensor. The material morphology and electrochemical characteristics were confirmed by spectroscopic and electrochemical methods. The present combination effectively modified the electrode surface and serve as a promising basis for the construction of Point-of-Care devices. Developed biosensor possesses wide operating linear range toward glucose detection from 50 μmol to 1000 μmol, with the limit of detection of 24 μmol. Finally, negligible interference effect and application in the real sample indicate that the proposed mechanism can be successfully applied to the assessment of glucose level in only one drop of real sample. PB - Elsevier T2 - Microchemical Journal T1 - TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor VL - 158 SP - 105150 DO - 10.1016/j.microc.2020.105150 ER -
@article{ author = "Ognjanović, Miloš and Stanković, Vesna and Knežević, Sara and Antić, Bratislav and Vranješ-Đurić, Sanja and Stanković, Dalibor", year = "2020", abstract = "Herein, we proposed a novel approach and state-of-the-art technology for the improvement of the materials and enzyme immobilization at the electrode surface and construction of impedimetric glucose biosensor. We silanized titanium dioxide nanoparticles using (3-aminopropyl)triethoxysilane (APTES), for the preparation of crosslinked material nanoparticles, with carboxylic graphene. The silanization of titanium dioxide nanoparticles and an increase in electron shuttle was proven feasible when this composite was able to achieve about 30% higher current than non-silanized material. The proposed approach was used for the modification of the printed threeelectrode system and the development of the impedimetric glucose biosensor. The material morphology and electrochemical characteristics were confirmed by spectroscopic and electrochemical methods. The present combination effectively modified the electrode surface and serve as a promising basis for the construction of Point-of-Care devices. Developed biosensor possesses wide operating linear range toward glucose detection from 50 μmol to 1000 μmol, with the limit of detection of 24 μmol. Finally, negligible interference effect and application in the real sample indicate that the proposed mechanism can be successfully applied to the assessment of glucose level in only one drop of real sample.", publisher = "Elsevier", journal = "Microchemical Journal", title = "TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor", volume = "158", pages = "105150", doi = "10.1016/j.microc.2020.105150" }
Ognjanović, M., Stanković, V., Knežević, S., Antić, B., Vranješ-Đurić, S.,& Stanković, D.. (2020). TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor. in Microchemical Journal Elsevier., 158, 105150. https://doi.org/10.1016/j.microc.2020.105150
Ognjanović M, Stanković V, Knežević S, Antić B, Vranješ-Đurić S, Stanković D. TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor. in Microchemical Journal. 2020;158:105150. doi:10.1016/j.microc.2020.105150 .
Ognjanović, Miloš, Stanković, Vesna, Knežević, Sara, Antić, Bratislav, Vranješ-Đurić, Sanja, Stanković, Dalibor, "TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor" in Microchemical Journal, 158 (2020):105150, https://doi.org/10.1016/j.microc.2020.105150 . .