Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts
Autori
Vujić, BojanVidaković, Vera
Jadranin, Milka
Novaković, Irena
Trifunović, Snežana
Tešević, Vele
Mandić, Boris
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal spec...ies. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.
Ključne reči:
Antimicrobial activity / Antioxidant potential / Helichrysum plicatum / Liquid chromatography-mass spectrometry (LC-MS) / Phenols / Solvent polarityIzvor:
Plants, 2020, 9, 3, 337-Izdavač:
- MDPI
Finansiranje / projekti:
- Bioaktivni prirodni proizvodi samoniklih, gajenih i jestivih biljaka: određivanje struktura i aktivnosti (RS-172053)
- Procena ekofiziološkog i genetičkog diverziteta biljaka u šumskim ekosistemima (RS-173011)
DOI: 10.3390/plants9030337
ISSN: 2223-7747
WoS: 000525315000029
Scopus: 2-s2.0-85082197649
URI
http://cherry.chem.bg.ac.rs/handle/123456789/3962http://ibiss-r.rcub.bg.ac.rs/handle/123456789/3620
https://cer.ihtm.bg.ac.rs/handle/123456789/3581
Institucija/grupa
IHTMTY - JOUR AU - Vujić, Bojan AU - Vidaković, Vera AU - Jadranin, Milka AU - Novaković, Irena AU - Trifunović, Snežana AU - Tešević, Vele AU - Mandić, Boris PY - 2020 UR - http://cherry.chem.bg.ac.rs/handle/123456789/3962 UR - http://ibiss-r.rcub.bg.ac.rs/handle/123456789/3620 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/3581 AB - Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol. PB - MDPI T2 - Plants T1 - Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts VL - 9 IS - 3 SP - 337 DO - 10.3390/plants9030337 ER -
@article{ author = "Vujić, Bojan and Vidaković, Vera and Jadranin, Milka and Novaković, Irena and Trifunović, Snežana and Tešević, Vele and Mandić, Boris", year = "2020", abstract = "Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.", publisher = "MDPI", journal = "Plants", title = "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts", volume = "9", number = "3", pages = "337", doi = "10.3390/plants9030337" }
Vujić, B., Vidaković, V., Jadranin, M., Novaković, I., Trifunović, S., Tešević, V.,& Mandić, B.. (2020). Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants MDPI., 9(3), 337. https://doi.org/10.3390/plants9030337
Vujić B, Vidaković V, Jadranin M, Novaković I, Trifunović S, Tešević V, Mandić B. Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants. 2020;9(3):337. doi:10.3390/plants9030337 .
Vujić, Bojan, Vidaković, Vera, Jadranin, Milka, Novaković, Irena, Trifunović, Snežana, Tešević, Vele, Mandić, Boris, "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts" in Plants, 9, no. 3 (2020):337, https://doi.org/10.3390/plants9030337 . .