Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil
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2017
Authors
Aćimović, MilicaPavlovic, Snezana D.
Varga, Ana
Filipović, Vladimir M.
Cvetković, Mirjana
Stanković, Jovana
Čabarkapa, Ivana
Article (Published version)
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Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.
Keywords:
Angelica / Staphylococcus aureus / Escherichia coli / MIC / MBCSource:
Natural Product Communications, 2017, 12, 2, 205-206Publisher:
- Natural Product Incorporation
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IHTMTY - JOUR AU - Aćimović, Milica AU - Pavlovic, Snezana D. AU - Varga, Ana AU - Filipović, Vladimir M. AU - Cvetković, Mirjana AU - Stanković, Jovana AU - Čabarkapa, Ivana PY - 2017 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2192 AB - Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria. PB - Natural Product Incorporation T2 - Natural Product Communications T1 - Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil VL - 12 IS - 2 SP - 205 EP - 206 UR - https://hdl.handle.net/21.15107/rcub_cer_2192 ER -
@article{ author = "Aćimović, Milica and Pavlovic, Snezana D. and Varga, Ana and Filipović, Vladimir M. and Cvetković, Mirjana and Stanković, Jovana and Čabarkapa, Ivana", year = "2017", abstract = "Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.", publisher = "Natural Product Incorporation", journal = "Natural Product Communications", title = "Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil", volume = "12", number = "2", pages = "205-206", url = "https://hdl.handle.net/21.15107/rcub_cer_2192" }
Aćimović, M., Pavlovic, S. D., Varga, A., Filipović, V. M., Cvetković, M., Stanković, J.,& Čabarkapa, I.. (2017). Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil. in Natural Product Communications Natural Product Incorporation., 12(2), 205-206. https://hdl.handle.net/21.15107/rcub_cer_2192
Aćimović M, Pavlovic SD, Varga A, Filipović VM, Cvetković M, Stanković J, Čabarkapa I. Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil. in Natural Product Communications. 2017;12(2):205-206. https://hdl.handle.net/21.15107/rcub_cer_2192 .
Aćimović, Milica, Pavlovic, Snezana D., Varga, Ana, Filipović, Vladimir M., Cvetković, Mirjana, Stanković, Jovana, Čabarkapa, Ivana, "Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil" in Natural Product Communications, 12, no. 2 (2017):205-206, https://hdl.handle.net/21.15107/rcub_cer_2192 .