Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties
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2017
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A comparative analysis of the phenolic compounds in the 70% EtOH extracts of Hypericum acutum, H. androsaemum, H. barbatum, H hirsutum, H maculatum, and H richeri has been carried out using high-performance liquid chromatography coupled with photodiode array UV detection and high resolution TOF mass spectrometry. Quercetin, astilbin, I3,II8-biapigenin, orientin, 2"-O-acetylorientin, three phenolcarboxylic acids, and eight flavonols 3-O-glycosides were identified in the extracts on the basis of their on-line UV spectra, accurate mass spectral data, and in comparison of retention times with those from the standards. Fingerprint analysis of the extracts revealed significant differences in the qualitative and quantitative chemical composition of the studied species. Antioxidant assays with various reaction mechanisms were used including ferric reducing antioxidant power (FRAP) assay, DPPH, ABTS, superoxide anion radical scavenging capacity and inhibition of liposome peroxidation induced by... Fe2+. The most potent were extracts of H acutum and H maculatum indicating this Hypericum species interesting for further research aimed as a potentially new source of biologically active compounds.
Ključne reči:
Hypericum species / Chemical analysis / LC/MS / HPLC/DAD / Antioxidant activityIzvor:
Natural Product Communications, 2017, 12, 11, 1805-1811Izdavač:
- Natural Product Incorporation
DOI: 10.1177/1934578X1701201140
ISSN: 1934-578X
WoS: 000417552000039
Scopus: 2-s2.0-85035243200
Institucija/grupa
IHTMTY - JOUR AU - Zdunić, Gordana AU - Gođevac, Dejan AU - Savikin, Katarina AU - Petrovic, Silvana PY - 2017 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2118 AB - A comparative analysis of the phenolic compounds in the 70% EtOH extracts of Hypericum acutum, H. androsaemum, H. barbatum, H hirsutum, H maculatum, and H richeri has been carried out using high-performance liquid chromatography coupled with photodiode array UV detection and high resolution TOF mass spectrometry. Quercetin, astilbin, I3,II8-biapigenin, orientin, 2"-O-acetylorientin, three phenolcarboxylic acids, and eight flavonols 3-O-glycosides were identified in the extracts on the basis of their on-line UV spectra, accurate mass spectral data, and in comparison of retention times with those from the standards. Fingerprint analysis of the extracts revealed significant differences in the qualitative and quantitative chemical composition of the studied species. Antioxidant assays with various reaction mechanisms were used including ferric reducing antioxidant power (FRAP) assay, DPPH, ABTS, superoxide anion radical scavenging capacity and inhibition of liposome peroxidation induced by Fe2+. The most potent were extracts of H acutum and H maculatum indicating this Hypericum species interesting for further research aimed as a potentially new source of biologically active compounds. PB - Natural Product Incorporation T2 - Natural Product Communications T1 - Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties VL - 12 IS - 11 SP - 1805 EP - 1811 DO - 10.1177/1934578X1701201140 ER -
@article{ author = "Zdunić, Gordana and Gođevac, Dejan and Savikin, Katarina and Petrovic, Silvana", year = "2017", abstract = "A comparative analysis of the phenolic compounds in the 70% EtOH extracts of Hypericum acutum, H. androsaemum, H. barbatum, H hirsutum, H maculatum, and H richeri has been carried out using high-performance liquid chromatography coupled with photodiode array UV detection and high resolution TOF mass spectrometry. Quercetin, astilbin, I3,II8-biapigenin, orientin, 2"-O-acetylorientin, three phenolcarboxylic acids, and eight flavonols 3-O-glycosides were identified in the extracts on the basis of their on-line UV spectra, accurate mass spectral data, and in comparison of retention times with those from the standards. Fingerprint analysis of the extracts revealed significant differences in the qualitative and quantitative chemical composition of the studied species. Antioxidant assays with various reaction mechanisms were used including ferric reducing antioxidant power (FRAP) assay, DPPH, ABTS, superoxide anion radical scavenging capacity and inhibition of liposome peroxidation induced by Fe2+. The most potent were extracts of H acutum and H maculatum indicating this Hypericum species interesting for further research aimed as a potentially new source of biologically active compounds.", publisher = "Natural Product Incorporation", journal = "Natural Product Communications", title = "Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties", volume = "12", number = "11", pages = "1805-1811", doi = "10.1177/1934578X1701201140" }
Zdunić, G., Gođevac, D., Savikin, K.,& Petrovic, S.. (2017). Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties. in Natural Product Communications Natural Product Incorporation., 12(11), 1805-1811. https://doi.org/10.1177/1934578X1701201140
Zdunić G, Gođevac D, Savikin K, Petrovic S. Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties. in Natural Product Communications. 2017;12(11):1805-1811. doi:10.1177/1934578X1701201140 .
Zdunić, Gordana, Gođevac, Dejan, Savikin, Katarina, Petrovic, Silvana, "Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties" in Natural Product Communications, 12, no. 11 (2017):1805-1811, https://doi.org/10.1177/1934578X1701201140 . .