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Diagnostic spectroscopic and computer-aided evaluation of malignancy from UV/VIS spectra of clear pleural effusions
dc.creator | Jevtic, Dubravka R. | |
dc.creator | Avramov Ivić, Milka | |
dc.creator | Reljin, Irini S. | |
dc.creator | Reljin, Branimir D. | |
dc.creator | Plavec, Goran I. | |
dc.creator | Petrović, Slobodan D. | |
dc.creator | Mijin, Dušan | |
dc.date.accessioned | 2019-01-30T17:41:14Z | |
dc.date.available | 2019-01-30T17:41:14Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 0378-4371 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/1516 | |
dc.description.abstract | The automated, computer-aided method for differentiation and classification of malignant (M) from benign (B) cases, by analyzing the UV/VIS spectra of pleural effusions is described. It was shown that by two independent objective features, the maximum of Katz fractal dimension (KFDmax) and the area under normalized UV/VIS absorbance curve (Area), highly reliable M-B classification is possible. In the Area-KFDmax space M and B samples are linearly separable permitting thus the use of linear support vector machine as a classification tool. By analyzing 104 samples of UV/VIS spectra of pleural effusions (88 M and 16 B) collected from patients at the Clinic for Lung Diseases and Tuberculosis, Military Medical Academy in Belgrade, the accuracy of 95.45% for M cases and 100% for B cases are obtained by using the proposed method. It was shown that by applying some modifications, which are suggested in the paper, the accuracy of 100% for M cases can be reached. | en |
dc.publisher | Elsevier | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172013/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/44009/RS// | |
dc.rights | restrictedAccess | |
dc.source | Physica A: Statistical Mechanics and its Applications | |
dc.subject | Pleural effusions | en |
dc.subject | Malignancy | en |
dc.subject | Katz fractal dimension | en |
dc.subject | UV/VIS diagnostic method | en |
dc.subject | Clinical praxis | en |
dc.title | Diagnostic spectroscopic and computer-aided evaluation of malignancy from UV/VIS spectra of clear pleural effusions | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Рељин, Бранимир Д.; Јевтиц, Дубравка Р.; Aврамов Ивић, Милка; Петровић, Слободан Д.; Плавец, Горан И.; Мијин, Дусан З.; Рељин, Ирини С.; | |
dc.citation.volume | 403 | |
dc.citation.spage | 206 | |
dc.citation.epage | 216 | |
dc.citation.other | 403: 206-216 | |
dc.citation.rank | M22 | |
dc.identifier.doi | 10.1016/j.physa.2014.02.026 | |
dc.identifier.scopus | 2-s2.0-84897696030 | |
dc.identifier.wos | 000334085700022 | |
dc.type.version | publishedVersion |