Antibacterial Activity of the Essential Oil of Heracleum sibiricum
Samo za registrovane korisnike
2013
Autori
Miladinovic, Dragoljub L.Ilic, Budimir S.
Mihajilov-Krstev, Tatjana M.
Nikolic, Dejan M.
Cvetković, Olga
Marković, Marija S.
Miladinovic, Ljiljana C.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The composition and antimicrobial activity of the essential oil of Heracleum sibiricum L. (Apiaceae) was studied. The aerial part of plant was hydro-distilled and chemical composition of the essential oil was analyzed by GC and GC-MS. Forty-six compounds, corresponding to 95.12% of the total oil, were identified. Esters represented the major chemical class (69.55%) while the main constituents were octyl butanoate (36.82%), hexyl butanoate (16.08%), 1-octanol (13.62%) and octyl hexanoate (8.10%). Antibacterial activity of the essential oil and reference antibiotics against nine bacterial strains was tested by the broth microdilution method. The results of the bioassays showed that essential oil had slight antimicrobial activities against all tested microorganisms (MIC and MBC values were in the range of 2431.2 to 9724.8 mu g/mL). Reference antibiotics were active in concentrations between 0.5 and 16.0 mu g/mL. The results confirm that Gram-positive bacteria were more susceptible to the ...essential oil of H. sibiricum, in comparison with Gram-negative bacteria.
Ključne reči:
Heracleum sibiricum / Essential oil / Antibacterial activityIzvor:
Natural Product Communications, 2013, 8, 9, 1309-1311Izdavač:
- Natural Product Incorporation
Finansiranje / projekti:
- Električni proboj gasova, površinski procesi i primene (RS-171025)
- Geohemijska ispitivanja sedimentnih stena - fosilna goriva i zagađivači životne sredine (RS-176006)
Institucija/grupa
IHTMTY - JOUR AU - Miladinovic, Dragoljub L. AU - Ilic, Budimir S. AU - Mihajilov-Krstev, Tatjana M. AU - Nikolic, Dejan M. AU - Cvetković, Olga AU - Marković, Marija S. AU - Miladinovic, Ljiljana C. PY - 2013 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/1265 AB - The composition and antimicrobial activity of the essential oil of Heracleum sibiricum L. (Apiaceae) was studied. The aerial part of plant was hydro-distilled and chemical composition of the essential oil was analyzed by GC and GC-MS. Forty-six compounds, corresponding to 95.12% of the total oil, were identified. Esters represented the major chemical class (69.55%) while the main constituents were octyl butanoate (36.82%), hexyl butanoate (16.08%), 1-octanol (13.62%) and octyl hexanoate (8.10%). Antibacterial activity of the essential oil and reference antibiotics against nine bacterial strains was tested by the broth microdilution method. The results of the bioassays showed that essential oil had slight antimicrobial activities against all tested microorganisms (MIC and MBC values were in the range of 2431.2 to 9724.8 mu g/mL). Reference antibiotics were active in concentrations between 0.5 and 16.0 mu g/mL. The results confirm that Gram-positive bacteria were more susceptible to the essential oil of H. sibiricum, in comparison with Gram-negative bacteria. PB - Natural Product Incorporation T2 - Natural Product Communications T1 - Antibacterial Activity of the Essential Oil of Heracleum sibiricum VL - 8 IS - 9 SP - 1309 EP - 1311 UR - https://hdl.handle.net/21.15107/rcub_cer_1265 ER -
@article{ author = "Miladinovic, Dragoljub L. and Ilic, Budimir S. and Mihajilov-Krstev, Tatjana M. and Nikolic, Dejan M. and Cvetković, Olga and Marković, Marija S. and Miladinovic, Ljiljana C.", year = "2013", abstract = "The composition and antimicrobial activity of the essential oil of Heracleum sibiricum L. (Apiaceae) was studied. The aerial part of plant was hydro-distilled and chemical composition of the essential oil was analyzed by GC and GC-MS. Forty-six compounds, corresponding to 95.12% of the total oil, were identified. Esters represented the major chemical class (69.55%) while the main constituents were octyl butanoate (36.82%), hexyl butanoate (16.08%), 1-octanol (13.62%) and octyl hexanoate (8.10%). Antibacterial activity of the essential oil and reference antibiotics against nine bacterial strains was tested by the broth microdilution method. The results of the bioassays showed that essential oil had slight antimicrobial activities against all tested microorganisms (MIC and MBC values were in the range of 2431.2 to 9724.8 mu g/mL). Reference antibiotics were active in concentrations between 0.5 and 16.0 mu g/mL. The results confirm that Gram-positive bacteria were more susceptible to the essential oil of H. sibiricum, in comparison with Gram-negative bacteria.", publisher = "Natural Product Incorporation", journal = "Natural Product Communications", title = "Antibacterial Activity of the Essential Oil of Heracleum sibiricum", volume = "8", number = "9", pages = "1309-1311", url = "https://hdl.handle.net/21.15107/rcub_cer_1265" }
Miladinovic, D. L., Ilic, B. S., Mihajilov-Krstev, T. M., Nikolic, D. M., Cvetković, O., Marković, M. S.,& Miladinovic, L. C.. (2013). Antibacterial Activity of the Essential Oil of Heracleum sibiricum. in Natural Product Communications Natural Product Incorporation., 8(9), 1309-1311. https://hdl.handle.net/21.15107/rcub_cer_1265
Miladinovic DL, Ilic BS, Mihajilov-Krstev TM, Nikolic DM, Cvetković O, Marković MS, Miladinovic LC. Antibacterial Activity of the Essential Oil of Heracleum sibiricum. in Natural Product Communications. 2013;8(9):1309-1311. https://hdl.handle.net/21.15107/rcub_cer_1265 .
Miladinovic, Dragoljub L., Ilic, Budimir S., Mihajilov-Krstev, Tatjana M., Nikolic, Dejan M., Cvetković, Olga, Marković, Marija S., Miladinovic, Ljiljana C., "Antibacterial Activity of the Essential Oil of Heracleum sibiricum" in Natural Product Communications, 8, no. 9 (2013):1309-1311, https://hdl.handle.net/21.15107/rcub_cer_1265 .