An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides
Samo za registrovane korisnike
2012
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Two sets of new peptides incorporating fulleropyrrolidine units Fp-GABAn-Glym-OtBu have been designed, synthesized and completely characterized. In the first series the chain contained only GABA (?-aminobutyric) residues, whereas in the second one glycine moieties were also inserted as well as GABA. Most of the target compounds were prepared by DCC/DMAP-assisted coupling of previously synthesized GABA-containing fulleropyrrolidinic acid and corresponding C-protected small peptides, although for two fulleropeptides [3+2] cycloadditions of azomethine ylides to C60 were employed. All new compounds were characterized by standard spectroscopic methods. Complete assignments of peptide spin systems were achieved by extensive NMR analysis (1H, 13C, H,H-COSY, HSQC, HMBC and TOCSY).
Ključne reči:
Synthetic methods / Peptidomimetics / Fullerenes / Fulleropeptides / Nano particlesIzvor:
European Journal of Organic Chemistry, 2012, 27, 5291-5300Izdavač:
- Wiley-V C H Verlag Gmbh, Weinheim
Finansiranje / projekti:
- Dizajn, sinteza i ispitivanje nanomolekulskih mašina na bazi fulerena (RS-MESTD-Basic Research (BR or ON)-172002)
DOI: 10.1002/ejoc.201200274
ISSN: 1434-193X
WoS: 000308580800020
Scopus: 2-s2.0-84866260060
Institucija/grupa
IHTMTY - JOUR AU - Bjelaković, Mira AU - Todorović, Nina AU - Milić, Dragana PY - 2012 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/1106 AB - Two sets of new peptides incorporating fulleropyrrolidine units Fp-GABAn-Glym-OtBu have been designed, synthesized and completely characterized. In the first series the chain contained only GABA (?-aminobutyric) residues, whereas in the second one glycine moieties were also inserted as well as GABA. Most of the target compounds were prepared by DCC/DMAP-assisted coupling of previously synthesized GABA-containing fulleropyrrolidinic acid and corresponding C-protected small peptides, although for two fulleropeptides [3+2] cycloadditions of azomethine ylides to C60 were employed. All new compounds were characterized by standard spectroscopic methods. Complete assignments of peptide spin systems were achieved by extensive NMR analysis (1H, 13C, H,H-COSY, HSQC, HMBC and TOCSY). PB - Wiley-V C H Verlag Gmbh, Weinheim T2 - European Journal of Organic Chemistry T1 - An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides IS - 27 SP - 5291 EP - 5300 DO - 10.1002/ejoc.201200274 ER -
@article{ author = "Bjelaković, Mira and Todorović, Nina and Milić, Dragana", year = "2012", abstract = "Two sets of new peptides incorporating fulleropyrrolidine units Fp-GABAn-Glym-OtBu have been designed, synthesized and completely characterized. In the first series the chain contained only GABA (?-aminobutyric) residues, whereas in the second one glycine moieties were also inserted as well as GABA. Most of the target compounds were prepared by DCC/DMAP-assisted coupling of previously synthesized GABA-containing fulleropyrrolidinic acid and corresponding C-protected small peptides, although for two fulleropeptides [3+2] cycloadditions of azomethine ylides to C60 were employed. All new compounds were characterized by standard spectroscopic methods. Complete assignments of peptide spin systems were achieved by extensive NMR analysis (1H, 13C, H,H-COSY, HSQC, HMBC and TOCSY).", publisher = "Wiley-V C H Verlag Gmbh, Weinheim", journal = "European Journal of Organic Chemistry", title = "An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides", number = "27", pages = "5291-5300", doi = "10.1002/ejoc.201200274" }
Bjelaković, M., Todorović, N.,& Milić, D.. (2012). An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides. in European Journal of Organic Chemistry Wiley-V C H Verlag Gmbh, Weinheim.(27), 5291-5300. https://doi.org/10.1002/ejoc.201200274
Bjelaković M, Todorović N, Milić D. An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides. in European Journal of Organic Chemistry. 2012;(27):5291-5300. doi:10.1002/ejoc.201200274 .
Bjelaković, Mira, Todorović, Nina, Milić, Dragana, "An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides" in European Journal of Organic Chemistry, no. 27 (2012):5291-5300, https://doi.org/10.1002/ejoc.201200274 . .