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Isolation and Biological Evaluation of Jatrophane Diterpenoids from Euphorbia dendroides
| dc.creator | Aljančić, Ivana | |
| dc.creator | Pešić, Milica | |
| dc.creator | Milosavljević, Slobodan | |
| dc.creator | Todorović, Nina | |
| dc.creator | Jadranin, Milka | |
| dc.creator | Miosavljevic, Goran | |
| dc.creator | Povrenovic, Dragan | |
| dc.creator | Bankovic, Jasna | |
| dc.creator | Tanic, Nikola | |
| dc.creator | Markovic, Ivanka D. | |
| dc.creator | Ruzdijic, Sabera | |
| dc.creator | Vajs, Vlatka | |
| dc.creator | Tešević, Vele | |
| dc.date.accessioned | 2019-01-30T17:27:54Z | |
| dc.date.available | 2019-01-30T17:27:54Z | |
| dc.date.issued | 2011 | |
| dc.identifier.issn | 0163-3864 | |
| dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/883 | |
| dc.description.abstract | From the Montenegrin spurge Euphorbia dendroides, seven new diterpenoids [jatrophanes (1-6) and a tigliane (7)] were isolated and their structures elucidated by spectroscopic techniques. The biological activity of the new compounds was studied against four human cancer cell lines. The most effective jatrophane-type compound (2) and its structurally closely related derivative (1) were evaluated for their interactions with paclitaxel and doxorubicin using a multidrug-resistant cancer cell line. Both compounds exerted a strong reversal potential resulting from inhibition of P-glycoprotein transport. | en |
| dc.publisher | American Chemical Society (ACS) | |
| dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS// | |
| dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41031/RS// | |
| dc.rights | restrictedAccess | |
| dc.source | Journal of Natural Products | |
| dc.title | Isolation and Biological Evaluation of Jatrophane Diterpenoids from Euphorbia dendroides | en |
| dc.type | article | |
| dc.rights.license | ARR | |
| dcterms.abstract | Песиц, Милица; Тодоровић, Нина; Банковиц, Јасна; Таниц, Никола; Руздијиц, Сабера; Вајс, Влатка Е.; Марковиц, Иванка Д.; Тесевиц, Веле В.; Aљанчић, Ивана С.; Милосављевиц, Слободан М.; Миосављевиц, Горан; Повреновиц, Драган; Јадранин, Милка; | |
| dc.citation.volume | 74 | |
| dc.citation.issue | 7 | |
| dc.citation.spage | 1613 | |
| dc.citation.epage | 1620 | |
| dc.citation.other | 74(7): 1613-1620 | |
| dc.citation.rank | M21 | |
| dc.identifier.pmid | 21707046 | |
| dc.identifier.doi | 10.1021/np200241c | |
| dc.identifier.scopus | 2-s2.0-79960728011 | |
| dc.identifier.wos | 000293036100009 | |
| dc.type.version | publishedVersion |
