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Microcystins: Potential risk factors in carcinogenesis of primary liver cancer in Serbia

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2011
872.pdf (844.1Kb)
Аутори
Drobac, Damjana
Svirčev, Zorica
Tokodi, Nada
Vidović, Milka
Baltić, Vladimir
Božić-Krstić, Verica
Lazić, Dragana
Pavlica, Tatjana
Чланак у часопису (Објављена верзија)
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Апстракт
The Primary Liver Carcinoma (PLC) is one of the most common malignant diseases in the world. In Central Serbia during the period from 2000 to 2006 the average incidence was 16.9/100 000 that complies to the European epidemiology. The main risk factors for PLC are considered to be cirrhosis of liver and viral chronic Hepatitis B and C. The goal of this research was to analyze epidemiological data of these diseases and to state the correlation between PLC, liver cirrhosis and Hepatitis B and C in Serbia. During the research period of 6 years the correlations between PLC and the corresponding risk factors were negative. For this reason it was necessary to examine other risk factors. The high incidence of PLC in Nišavski, Toplički and Šumadijski region correlate with emerging blooms of Cyanobacteria in water reservoirs supplying these areas with drinking water. Since we examined only 7 years span and have no completed cyanotoxin analysis, it is necessary to complete more research in this f...ield. The identification of cyanotoxins as risk factors that contribute to the development of liver cancer will help in the prevention of this disease.

Кључне речи:
PLC / Central Serbia / rick factors / cirrhosis / HBV / HCV / microcystin
Извор:
Geographica Pannonica, 2011, 15, 3, 70-80
Издавач:
  • University of Novi Sad, Department of Geography, Tourism and Hotel Management
Пројекти:
  • Трансформације геопростора Србије - прошлост, савремени проблеми и предлози решења (RS-176020)

DOI: 10.5937/GeoPan1103070D

ISSN: 0354-8724

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URI
http://cer.ihtm.bg.ac.rs/handle/123456789/874
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  • Radovi istraživača / Researchers' publications
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