The impact of Schiff bases on antibiotic production by Streptomyces hygroscopicus
2010
Authors
Ilić, Slavica B.Konstantinović, Sandra S.
Savić, D.S.
Veljković, Vlada B.
Gojgić-Cvijović, Gordana
Article (Published version)
Metadata
Show full item recordAbstract
A media consisting of isatin-Schiff bases (isatin-3-thiosemicarbazone, isatin-3-semicarbazone, and isatin-3-phenylhydrazone) was developed to maximize the production of antibiotics Hexaene H-85 and Azalomycine B by Streptomyces hygroscopicus. The media isatin-3-thiosemicarbazone resulted in the maximum antibiotics concentration of 372 μg cm-3 for Hexaene H-85 and 118 μg cm-3 for Azalomycine B. The impact of modified media on soil morphology also was investigated.
Keywords:
Antibiotic production / Morphology / Schiff base / Streptomyces hygroscopicusSource:
Medicinal Chemistry Research, 2010, 19, 7, 690-697
DOI: 10.1007/s00044-009-9223-7
ISSN: 1054-2523
WoS: 000280557700007
Scopus: 2-s2.0-77956484743
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