Micromolar Levofloxacin Sensor by Incorporating Highly Crystalline Co3O4 into a Carbon Paste Electrode Structure
Autori
Mutić, TijanaStanković, Dalibor
Manojlović, Dragan
Petrić, Djordje
Pastor, Ferenc
Avdin, Vyacheslav V.
Ognjanović, Miloš
Stanković, Vesna
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
In this work, we successfully prepared a modified cobalt oxide (Co3O4) carbon paste electrode to detect Levofloxacin (LEV). By synthesizing Co3O4 nanoparticles through the chemical coprecipitation method, the electrochemical properties of the electrode and LEV were thoroughly investigated using CV, SWV, and EIS, while material properties were scrutinized using ICP-OES, TEM, SEM, and XRD. The results showed that the prepared electrode displayed a better electrocatalytic response than the bare carbon paste electrode. After optimizing SWV, the electrode exhibited a wide linear working range from 1 to 85 μM at pH 5 of BRBS as the supporting electrolyte. The selectivity of the proposed method was satisfactory, with good repeatability and reproducibility, strongly suggesting a potential application for determining LEV in real samples, particularly in pharmaceutical formulations. The practicality of the approach was demonstrated through good recoveries, and the morphology of the materials was... found to be closely related to other parameters, indicating that the developed method can provide a cost-effective, rapid, selective, and sensitive means for LEV monitoring. Overall, this project has made significant progress towards developing a reliable method for detecting LEV and has opened up new opportunities for future research in this field.
Ključne reči:
electrochemical sensor / carbon paste electrode / antibioticsIzvor:
Electrochem, 2024, 5, 1, 45-56Izdavač:
- MDPI AG
Finansiranje / projekti:
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200026 (Univerzitet u Beogradu, Institut za hemiju, tehnologiju i metalurgiju - IHTM) (RS-MESTD-inst-2020-200026)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200168 (Univerzitet u Beogradu, Hemijski fakultet) (RS-MESTD-inst-2020-200168)
- Ministry of Science and Higher Education of the Russian Federation (agreement No. 075-15-2022-1135) and South Ural State University
Institucija/grupa
IHTMTY - JOUR AU - Mutić, Tijana AU - Stanković, Dalibor AU - Manojlović, Dragan AU - Petrić, Djordje AU - Pastor, Ferenc AU - Avdin, Vyacheslav V. AU - Ognjanović, Miloš AU - Stanković, Vesna PY - 2024 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/7422 AB - In this work, we successfully prepared a modified cobalt oxide (Co3O4) carbon paste electrode to detect Levofloxacin (LEV). By synthesizing Co3O4 nanoparticles through the chemical coprecipitation method, the electrochemical properties of the electrode and LEV were thoroughly investigated using CV, SWV, and EIS, while material properties were scrutinized using ICP-OES, TEM, SEM, and XRD. The results showed that the prepared electrode displayed a better electrocatalytic response than the bare carbon paste electrode. After optimizing SWV, the electrode exhibited a wide linear working range from 1 to 85 μM at pH 5 of BRBS as the supporting electrolyte. The selectivity of the proposed method was satisfactory, with good repeatability and reproducibility, strongly suggesting a potential application for determining LEV in real samples, particularly in pharmaceutical formulations. The practicality of the approach was demonstrated through good recoveries, and the morphology of the materials was found to be closely related to other parameters, indicating that the developed method can provide a cost-effective, rapid, selective, and sensitive means for LEV monitoring. Overall, this project has made significant progress towards developing a reliable method for detecting LEV and has opened up new opportunities for future research in this field. PB - MDPI AG T2 - Electrochem T1 - Micromolar Levofloxacin Sensor by Incorporating Highly Crystalline Co3O4 into a Carbon Paste Electrode Structure VL - 5 IS - 1 SP - 45 EP - 56 DO - 10.3390/electrochem5010003 ER -
@article{ author = "Mutić, Tijana and Stanković, Dalibor and Manojlović, Dragan and Petrić, Djordje and Pastor, Ferenc and Avdin, Vyacheslav V. and Ognjanović, Miloš and Stanković, Vesna", year = "2024", abstract = "In this work, we successfully prepared a modified cobalt oxide (Co3O4) carbon paste electrode to detect Levofloxacin (LEV). By synthesizing Co3O4 nanoparticles through the chemical coprecipitation method, the electrochemical properties of the electrode and LEV were thoroughly investigated using CV, SWV, and EIS, while material properties were scrutinized using ICP-OES, TEM, SEM, and XRD. The results showed that the prepared electrode displayed a better electrocatalytic response than the bare carbon paste electrode. After optimizing SWV, the electrode exhibited a wide linear working range from 1 to 85 μM at pH 5 of BRBS as the supporting electrolyte. The selectivity of the proposed method was satisfactory, with good repeatability and reproducibility, strongly suggesting a potential application for determining LEV in real samples, particularly in pharmaceutical formulations. The practicality of the approach was demonstrated through good recoveries, and the morphology of the materials was found to be closely related to other parameters, indicating that the developed method can provide a cost-effective, rapid, selective, and sensitive means for LEV monitoring. Overall, this project has made significant progress towards developing a reliable method for detecting LEV and has opened up new opportunities for future research in this field.", publisher = "MDPI AG", journal = "Electrochem", title = "Micromolar Levofloxacin Sensor by Incorporating Highly Crystalline Co3O4 into a Carbon Paste Electrode Structure", volume = "5", number = "1", pages = "45-56", doi = "10.3390/electrochem5010003" }
Mutić, T., Stanković, D., Manojlović, D., Petrić, D., Pastor, F., Avdin, V. V., Ognjanović, M.,& Stanković, V.. (2024). Micromolar Levofloxacin Sensor by Incorporating Highly Crystalline Co3O4 into a Carbon Paste Electrode Structure. in Electrochem MDPI AG., 5(1), 45-56. https://doi.org/10.3390/electrochem5010003
Mutić T, Stanković D, Manojlović D, Petrić D, Pastor F, Avdin VV, Ognjanović M, Stanković V. Micromolar Levofloxacin Sensor by Incorporating Highly Crystalline Co3O4 into a Carbon Paste Electrode Structure. in Electrochem. 2024;5(1):45-56. doi:10.3390/electrochem5010003 .
Mutić, Tijana, Stanković, Dalibor, Manojlović, Dragan, Petrić, Djordje, Pastor, Ferenc, Avdin, Vyacheslav V., Ognjanović, Miloš, Stanković, Vesna, "Micromolar Levofloxacin Sensor by Incorporating Highly Crystalline Co3O4 into a Carbon Paste Electrode Structure" in Electrochem, 5, no. 1 (2024):45-56, https://doi.org/10.3390/electrochem5010003 . .