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Sinteza i in vitro antitumourska aktivnost novih mimetika goniofufurona sa tiofenskim prstenom na položaju C-7
Synthesis and in vitro antitumour activity of new goniofufurone mimics with thiophene ring at the C-7 position
dc.creator | Popsavin, Mirjana | |
dc.creator | Kovačević, Ivana | |
dc.creator | Kekezović, Slađana | |
dc.creator | Svirčev, Miloš | |
dc.creator | Srećo Zelenović, Bojana | |
dc.creator | Kojić, Vesna V. | |
dc.creator | Jadranin, Milka | |
dc.creator | Popsavin, Velimir | |
dc.date.accessioned | 2023-12-19T15:00:26Z | |
dc.date.available | 2023-12-19T15:00:26Z | |
dc.date.issued | 2018 | |
dc.identifier.isbn | 978-86-7132-069-6 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/7095 | |
dc.description.abstract | Ostvarena je višefazna sinteza novih mimetika (+)-goniofufurona (1) sa tiofenskim prstenom umesto fenil grupe u položaju C-7 polazeći iz D-glukoze (Shema 1). Ispitana je in vitro citotoksična aktivnost novosintetizovanih mimetika prema odabranim tumorskim ćelijskim linijama, kao i prema jednoj normalnoj ćelijskoj liniji (fetalni fibroblasti pluća, MRC-5). | sr |
dc.description.abstract | Multiphase synthesis of (+)-goniofufurone (1) mimetics with thiofene ring instead of phenyl group at the C-7 position is completed using D-glucose as a starting compound (Scheme 1). In vitro cytotoxicity of newly synthetized analogues against eleven human tumour cell lines and against a single normal cell line (MRC-5) was evaluated. | sr |
dc.language.iso | sr | sr |
dc.language.iso | en | sr |
dc.publisher | Belgrade : Serbian Chemical Society | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172006/RS// | sr |
dc.rights | openAccess | sr |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Kratki izvodi radova - 55. Savetovanje Srpskog hemijskog društva, 8. i 9. juni 2018, Novi Sad / Book of abstracts - 55 Meeting of the Serbian Chemical Society, June 8-9, 2018, Novi Sad | sr |
dc.subject | sinteza | sr |
dc.subject | synthesis | sr |
dc.title | Sinteza i in vitro antitumourska aktivnost novih mimetika goniofufurona sa tiofenskim prstenom na položaju C-7 | sr |
dc.title | Synthesis and in vitro antitumour activity of new goniofufurone mimics with thiophene ring at the C-7 position | sr |
dc.type | conferenceObject | sr |
dc.rights.license | BY-NC-ND | sr |
dc.citation.spage | 82 | |
dc.citation.epage | 82 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_cer_7095 | |
dc.identifier.fulltext | http://cer.ihtm.bg.ac.rs/bitstream/id/28673/SHD55_Book_of_abstractsjadranin.pdf | |
dc.type.version | publishedVersion | sr |