Supplementary information for: "Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation"
Аутори
Kozarski, MajaKlaus, Anita
Špirović Trifunović, Bojana
Miletić, Srđan
Lazić, Vesna
Žižak, Željko
Vunduk, Jovana
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Метаподаци
Приказ свих података о документуАпстракт
Growing mushrooms is meeting challenges while aiming for sustainability and circularity. Wherever the producer is located, commercial strains are the same originating from several producers. Following the harvest, enormous quantities of spent mushroom substrate containing spores are disposed presenting a type of foreign material pressure on the ecosystem in the form of the loss of genetic diversity in wild mushroom populations. This challenge can be mitigated by bioprospecting local strains and using them to generate commercial inoculum. Accordingly, the mycoceutical potential of five polypore mushroom species from Serbia was evaluated: secondary metabolite composition, oxidative damage prevention, anti-tyrosinase, and antiangiotensin converting enzyme (ACE) properties. The phenolic pattern was comparable in all samples, but the amounts of specific chemicals varied. Hydroxybenzoic acids were the primary components. All samples had varying quantities of ascorbic acid, carotene, and lyco...pene, and showed a pronounced inhibition of lipid peroxidation (LPx) and ability to scavenge HO•. Extracts were more potent tyrosinase inhibitors but unsuccessful when faced with ACE. Fomitopsis pinicola had the strongest anti-tumor efficacy while Ganoderma lucidum demonstrated strong selectivity in anti-tumor effect in comparison to healthy cells. The evaluated species provided a solid foundation for commercial development while keeping the local ecology in mind.
Кључне речи:
biological activity / bioprospecting / Coriolus / Fomitopsis / Ganoderma / mushroom cultivation / oxidative damage prevention / PolyporeИзвор:
Preprints, 2023Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200026 (Универзитет у Београду, Институт за хемију, технологију и металургију - ИХТМ) (RS-MESTD-inst-2020-200026)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200051 (Институт за општу и физичку хемију, Београд) (RS-MESTD-inst-2020-200051)
Напомена:
- This is supplementary information for: Kozarski M, Klaus A, Špirović Trifunović B, Miletić S, Lazić V, Žižak Ž, Vunduk J. Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation. in Preprints. 2023;:2023111765. doi: https://dx.doi.org/10.20944/preprints202311.1765.v1
- Pre-print version of the mansucript: https://cer.ihtm.bg.ac.rs/handle/123456789/7057
Повезане информације:
- Повезани садржај
https://cer.ihtm.bg.ac.rs/handle/123456789/7057
URI
https://www.preprints.org/manuscript/202311.1765/v1https://cer.ihtm.bg.ac.rs/handle/123456789/7057
https://cer.ihtm.bg.ac.rs/handle/123456789/7058
Колекције
Институција/група
IHTMTY - DATA AU - Kozarski, Maja AU - Klaus, Anita AU - Špirović Trifunović, Bojana AU - Miletić, Srđan AU - Lazić, Vesna AU - Žižak, Željko AU - Vunduk, Jovana PY - 2023 UR - https://www.preprints.org/manuscript/202311.1765/v1 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/7057 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/7058 AB - Growing mushrooms is meeting challenges while aiming for sustainability and circularity. Wherever the producer is located, commercial strains are the same originating from several producers. Following the harvest, enormous quantities of spent mushroom substrate containing spores are disposed presenting a type of foreign material pressure on the ecosystem in the form of the loss of genetic diversity in wild mushroom populations. This challenge can be mitigated by bioprospecting local strains and using them to generate commercial inoculum. Accordingly, the mycoceutical potential of five polypore mushroom species from Serbia was evaluated: secondary metabolite composition, oxidative damage prevention, anti-tyrosinase, and antiangiotensin converting enzyme (ACE) properties. The phenolic pattern was comparable in all samples, but the amounts of specific chemicals varied. Hydroxybenzoic acids were the primary components. All samples had varying quantities of ascorbic acid, carotene, and lycopene, and showed a pronounced inhibition of lipid peroxidation (LPx) and ability to scavenge HO•. Extracts were more potent tyrosinase inhibitors but unsuccessful when faced with ACE. Fomitopsis pinicola had the strongest anti-tumor efficacy while Ganoderma lucidum demonstrated strong selectivity in anti-tumor effect in comparison to healthy cells. The evaluated species provided a solid foundation for commercial development while keeping the local ecology in mind. T2 - Preprints T1 - Supplementary information for: "Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation" DO - 10.20944/preprints202311.1765.v1 ER -
@misc{ author = "Kozarski, Maja and Klaus, Anita and Špirović Trifunović, Bojana and Miletić, Srđan and Lazić, Vesna and Žižak, Željko and Vunduk, Jovana", year = "2023", abstract = "Growing mushrooms is meeting challenges while aiming for sustainability and circularity. Wherever the producer is located, commercial strains are the same originating from several producers. Following the harvest, enormous quantities of spent mushroom substrate containing spores are disposed presenting a type of foreign material pressure on the ecosystem in the form of the loss of genetic diversity in wild mushroom populations. This challenge can be mitigated by bioprospecting local strains and using them to generate commercial inoculum. Accordingly, the mycoceutical potential of five polypore mushroom species from Serbia was evaluated: secondary metabolite composition, oxidative damage prevention, anti-tyrosinase, and antiangiotensin converting enzyme (ACE) properties. The phenolic pattern was comparable in all samples, but the amounts of specific chemicals varied. Hydroxybenzoic acids were the primary components. All samples had varying quantities of ascorbic acid, carotene, and lycopene, and showed a pronounced inhibition of lipid peroxidation (LPx) and ability to scavenge HO•. Extracts were more potent tyrosinase inhibitors but unsuccessful when faced with ACE. Fomitopsis pinicola had the strongest anti-tumor efficacy while Ganoderma lucidum demonstrated strong selectivity in anti-tumor effect in comparison to healthy cells. The evaluated species provided a solid foundation for commercial development while keeping the local ecology in mind.", journal = "Preprints", title = "Supplementary information for: "Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation"", doi = "10.20944/preprints202311.1765.v1" }
Kozarski, M., Klaus, A., Špirović Trifunović, B., Miletić, S., Lazić, V., Žižak, Ž.,& Vunduk, J.. (2023). Supplementary information for: "Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation". in Preprints. https://doi.org/10.20944/preprints202311.1765.v1
Kozarski M, Klaus A, Špirović Trifunović B, Miletić S, Lazić V, Žižak Ž, Vunduk J. Supplementary information for: "Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation". in Preprints. 2023;. doi:10.20944/preprints202311.1765.v1 .
Kozarski, Maja, Klaus, Anita, Špirović Trifunović, Bojana, Miletić, Srđan, Lazić, Vesna, Žižak, Željko, Vunduk, Jovana, "Supplementary information for: "Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation"" in Preprints (2023), https://doi.org/10.20944/preprints202311.1765.v1 . .