Carbohydrate binding polypeptide of Savalia Savaglia
Само за регистроване кориснике
2023
Патент (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The present invention relates to a novel polypeptide which displays specific carbohydrate binding activity, particularly against glycans that contain mannose, and in vivo and ex vivo methods of use thereof. Methods of use comprise administering a polypeptide of the invention, for example to a sample or a subject in which carbohydrate is present, under conditions suitable for the polypeptide to bind the carbohydrate. The carbohydrate may be expressed by a pathogen. The invention relates to polypeptides and compositions thereof with anti-pathogen activity, such as anti-viral, anti-bacterial, anti-fungal or anti-tumour activity. Also provided are methods for the prevention or treatment of diseases and conditions mediated by pathogens which express carbohydrate, for example as glycoproteins.
Кључне речи:
Carbohydrate binding protein / HIV / HSV / Influenza / SARS-CoV-2 / mannose / anti-viral / anti-bacterial / anti-fungal / anti-tumourИзвор:
The World Intellectual Property Organization, 2023, WO20230552505A1Издавач:
- The World Intellectual Property Organization
Институција/група
IHTMTY - PAT AU - Andjelković, Uroš AU - Sladić, Dušan AU - Vukasinović, Ivana AU - Lah, Jurij AU - Fonovic, Marko PY - 2023 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/6941 AB - The present invention relates to a novel polypeptide which displays specific carbohydrate binding activity, particularly against glycans that contain mannose, and in vivo and ex vivo methods of use thereof. Methods of use comprise administering a polypeptide of the invention, for example to a sample or a subject in which carbohydrate is present, under conditions suitable for the polypeptide to bind the carbohydrate. The carbohydrate may be expressed by a pathogen. The invention relates to polypeptides and compositions thereof with anti-pathogen activity, such as anti-viral, anti-bacterial, anti-fungal or anti-tumour activity. Also provided are methods for the prevention or treatment of diseases and conditions mediated by pathogens which express carbohydrate, for example as glycoproteins. PB - The World Intellectual Property Organization T2 - The World Intellectual Property Organization T1 - Carbohydrate binding polypeptide of Savalia Savaglia IS - WO20230552505A1 UR - https://hdl.handle.net/21.15107/rcub_cer_6941 ER -
@misc{ author = "Andjelković, Uroš and Sladić, Dušan and Vukasinović, Ivana and Lah, Jurij and Fonovic, Marko", year = "2023", abstract = "The present invention relates to a novel polypeptide which displays specific carbohydrate binding activity, particularly against glycans that contain mannose, and in vivo and ex vivo methods of use thereof. Methods of use comprise administering a polypeptide of the invention, for example to a sample or a subject in which carbohydrate is present, under conditions suitable for the polypeptide to bind the carbohydrate. The carbohydrate may be expressed by a pathogen. The invention relates to polypeptides and compositions thereof with anti-pathogen activity, such as anti-viral, anti-bacterial, anti-fungal or anti-tumour activity. Also provided are methods for the prevention or treatment of diseases and conditions mediated by pathogens which express carbohydrate, for example as glycoproteins.", publisher = "The World Intellectual Property Organization", journal = "The World Intellectual Property Organization", title = "Carbohydrate binding polypeptide of Savalia Savaglia", number = "WO20230552505A1", url = "https://hdl.handle.net/21.15107/rcub_cer_6941" }
Andjelković, U., Sladić, D., Vukasinović, I., Lah, J.,& Fonovic, M.. (2023). Carbohydrate binding polypeptide of Savalia Savaglia. in The World Intellectual Property Organization The World Intellectual Property Organization.(WO20230552505A1). https://hdl.handle.net/21.15107/rcub_cer_6941
Andjelković U, Sladić D, Vukasinović I, Lah J, Fonovic M. Carbohydrate binding polypeptide of Savalia Savaglia. in The World Intellectual Property Organization. 2023;(WO20230552505A1). https://hdl.handle.net/21.15107/rcub_cer_6941 .
Andjelković, Uroš, Sladić, Dušan, Vukasinović, Ivana, Lah, Jurij, Fonovic, Marko, "Carbohydrate binding polypeptide of Savalia Savaglia" in The World Intellectual Property Organization, no. WO20230552505A1 (2023), https://hdl.handle.net/21.15107/rcub_cer_6941 .