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Synthesis and determination of in vitro biological activity of novel fulleropyrrolidines containing phenol subunit
dc.creator | Trifković, Željko | |
dc.creator | Kotlaja, Katarina | |
dc.creator | Kop, Tatjana | |
dc.creator | Milić, Dragana | |
dc.date.accessioned | 2023-11-22T06:09:11Z | |
dc.date.available | 2023-11-22T06:09:11Z | |
dc.date.issued | 2023 | |
dc.identifier.isbn | 978-86-7132-084-9 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/6895 | |
dc.description.abstract | Willing to obtain novel fulleropyrrolidines with improved biological activity, we explored the synthesis of hybrid structures containing fullerene and phenol. The Prato reaction of the glycine derivative, aromatic aldehydes with phenol subunit and the fullerene C60 provided desired products in satisfactory yields (Figure 1). DPPH radical scavenging activity and β–carotene-linoleic acid bleaching assay were used to determinate antioxidant activity, while for evaluation of anti-inflammatory activity, ovalbumin (OVA) and bovine serum albumin (BSA) thermal denaturation inhibition assays were used. Obtained results indicated that performed synthesis gave rise to compounds with dual activity. | sr |
dc.language.iso | en | sr |
dc.publisher | Belgrade : Serbian Chemical Society | sr |
dc.publisher | Belgrade : Serbian Young Chemists’ Club | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200026/RS// | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200168/RS// | sr |
dc.rights | openAccess | sr |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.source | 9th Conference of Young Chemists of Serbia, Book of abstracts, 4th November 2023, Novi Sad, Serbia | sr |
dc.subject | fulleropyrrolidines | sr |
dc.subject | Prato reaction | sr |
dc.title | Synthesis and determination of in vitro biological activity of novel fulleropyrrolidines containing phenol subunit | sr |
dc.type | conferenceObject | sr |
dc.rights.license | BY | sr |
dc.citation.spage | 76 | |
dc.citation.epage | 76 | |
dc.citation.rank | M64 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_cer_6895 | |
dc.identifier.fulltext | http://cer.ihtm.bg.ac.rs/bitstream/id/28003/bitstream_28003.pdf | |
dc.type.version | publishedVersion | sr |