The paramagnetic pillared bentonites as digestive tract mri contrast agents
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2010
Authors
Mojović, Miloš
Dakovic, Marko
Omerasevic, Mia
Mojović, Zorica

Banković, Predrag

Milutinović Nikolić, Aleksandra

Jovanović, Dušan M.
Article (Published version)

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The increased use of imaging techniques in diagnostic studies, such as MRI, has contributed to the development of the wide range of new materials which could be successfully used as image improving agents. However, there is a lack of such substances in the area of gastrointestinal tract MRI. Many of the traditionally popular relaxation altering agents show poor results and disadvantages provoking black bowel, side effects of diarrhea and the presence of artifacts arising from clumping. Paramagnetic species seem to be potentially suitable agents for these studies, but contrast opacification has been reported and less than 60% of the gastrointestinal tract magnetic resonance scans showed improved delineation of abdominal pathologies. The new solution has been proposed as zeolites or smectite clays (hectorite and montmorillonite) enclosing of paramagnetic metal ions obtained by ion-exchange methods. However, such materials have problems of leakage of paramagnetic ions causing the appearan...ce of the various side-effects. In this study we show that Co(+2) and Dy(+3) paramagnetic-pillared bentonites could be successfully used as MRI digestive tract non-leaching contrast agents, altering the longitudinal and transverse relaxation times of fluids in contact with the clay minerals.
Keywords:
Bentonites / pillaring / MRI contrast / digestive tractSource:
International Journal of Modern Physics B, 2010, 24, 6-7, 780-787Publisher:
- World Scientific Publ Co Pte Ltd, Singapore
Funding / projects:
- Sinteza, karakterizacija i testiranje katalitičkih svojstava specijalno dizajniranih materijala (RS-142019)
- Biofizička istraživanja membranskih procesa: interakcija membranskih receptora i kanala sa spoljašnjim faktorima i intracelularna regulacija (RS-143016)
- Mezoporozni i nanomaterijali u katalitičkim i sorpcionim procesima (RS-166001)
DOI: 10.1142/S0217979210064411
ISSN: 0217-9792
WoS: 000275932300017
Scopus: 2-s2.0-77951697278
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Institution/Community
IHTMTY - JOUR AU - Mojović, Miloš AU - Dakovic, Marko AU - Omerasevic, Mia AU - Mojović, Zorica AU - Banković, Predrag AU - Milutinović Nikolić, Aleksandra AU - Jovanović, Dušan M. PY - 2010 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/648 AB - The increased use of imaging techniques in diagnostic studies, such as MRI, has contributed to the development of the wide range of new materials which could be successfully used as image improving agents. However, there is a lack of such substances in the area of gastrointestinal tract MRI. Many of the traditionally popular relaxation altering agents show poor results and disadvantages provoking black bowel, side effects of diarrhea and the presence of artifacts arising from clumping. Paramagnetic species seem to be potentially suitable agents for these studies, but contrast opacification has been reported and less than 60% of the gastrointestinal tract magnetic resonance scans showed improved delineation of abdominal pathologies. The new solution has been proposed as zeolites or smectite clays (hectorite and montmorillonite) enclosing of paramagnetic metal ions obtained by ion-exchange methods. However, such materials have problems of leakage of paramagnetic ions causing the appearance of the various side-effects. In this study we show that Co(+2) and Dy(+3) paramagnetic-pillared bentonites could be successfully used as MRI digestive tract non-leaching contrast agents, altering the longitudinal and transverse relaxation times of fluids in contact with the clay minerals. PB - World Scientific Publ Co Pte Ltd, Singapore T2 - International Journal of Modern Physics B T1 - The paramagnetic pillared bentonites as digestive tract mri contrast agents VL - 24 IS - 6-7 SP - 780 EP - 787 DO - 10.1142/S0217979210064411 ER -
@article{ author = "Mojović, Miloš and Dakovic, Marko and Omerasevic, Mia and Mojović, Zorica and Banković, Predrag and Milutinović Nikolić, Aleksandra and Jovanović, Dušan M.", year = "2010", abstract = "The increased use of imaging techniques in diagnostic studies, such as MRI, has contributed to the development of the wide range of new materials which could be successfully used as image improving agents. However, there is a lack of such substances in the area of gastrointestinal tract MRI. Many of the traditionally popular relaxation altering agents show poor results and disadvantages provoking black bowel, side effects of diarrhea and the presence of artifacts arising from clumping. Paramagnetic species seem to be potentially suitable agents for these studies, but contrast opacification has been reported and less than 60% of the gastrointestinal tract magnetic resonance scans showed improved delineation of abdominal pathologies. The new solution has been proposed as zeolites or smectite clays (hectorite and montmorillonite) enclosing of paramagnetic metal ions obtained by ion-exchange methods. However, such materials have problems of leakage of paramagnetic ions causing the appearance of the various side-effects. In this study we show that Co(+2) and Dy(+3) paramagnetic-pillared bentonites could be successfully used as MRI digestive tract non-leaching contrast agents, altering the longitudinal and transverse relaxation times of fluids in contact with the clay minerals.", publisher = "World Scientific Publ Co Pte Ltd, Singapore", journal = "International Journal of Modern Physics B", title = "The paramagnetic pillared bentonites as digestive tract mri contrast agents", volume = "24", number = "6-7", pages = "780-787", doi = "10.1142/S0217979210064411" }
Mojović, M., Dakovic, M., Omerasevic, M., Mojović, Z., Banković, P., Milutinović Nikolić, A.,& Jovanović, D. M.. (2010). The paramagnetic pillared bentonites as digestive tract mri contrast agents. in International Journal of Modern Physics B World Scientific Publ Co Pte Ltd, Singapore., 24(6-7), 780-787. https://doi.org/10.1142/S0217979210064411
Mojović M, Dakovic M, Omerasevic M, Mojović Z, Banković P, Milutinović Nikolić A, Jovanović DM. The paramagnetic pillared bentonites as digestive tract mri contrast agents. in International Journal of Modern Physics B. 2010;24(6-7):780-787. doi:10.1142/S0217979210064411 .
Mojović, Miloš, Dakovic, Marko, Omerasevic, Mia, Mojović, Zorica, Banković, Predrag, Milutinović Nikolić, Aleksandra, Jovanović, Dušan M., "The paramagnetic pillared bentonites as digestive tract mri contrast agents" in International Journal of Modern Physics B, 24, no. 6-7 (2010):780-787, https://doi.org/10.1142/S0217979210064411 . .