CER - Central Repository
Institute of Chemistry, Technology and Metallurgy
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrilic)
    • Serbian (Latin)
  • Login
View Item 
  •   Central Repository
  • IHTM
  • Radovi istraživača / Researchers' publications
  • View Item
  •   Central Repository
  • IHTM
  • Radovi istraživača / Researchers' publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Synthesis, characterization and antitumor activity of novel N-substituted α-amino acids containing ferrocenyl pyrazole-moiety

Authorized Users Only
2009
Authors
Joksović, M.D.
Marković, V.
Juranić, Zorica
Stanojković, Tatjana
Jovanović, L.S.
Damljanović, I.S.
Szécsényi, K.M.
Todorović, Nina
Trifunović, Snežana
Vukićević, R.D.
Article (Published version)
Metadata
Show full item record
Abstract
A series of new N-[(3-ferrocenyl-1-phenylpyrazol-4-yl)methyl] α-amino acids were prepared and characterized by a range of spectroscopic techniques and cyclic voltammetry. The in vitro antitumor activity of all synthesized compounds was investigated against cervix adenocarcinoma HeLa, melanoma Fem-x and myelogenous leukemia K562 cell lines using the MTT method. Tryptophan derivative 1l exhibited the highest cytotoxic activity in the cell growth inhibition of all three types of cell lines.
Keywords:
Amino acids / cytotoxicity / Ferrocenyl pyrazole
Source:
Journal of Organometallic Chemistry, 2009, 694, 24, 3935-3942
Projects:
  • Sinteze, fizičke, strukturne i biološke karakteristike novih kompleksnih jedenjenja (RS-142028)
  • Razvoj novih elektrohemijskih i hemijskih metoda organske sinteze (RS-142042)
  • Istraživanje dejstava modifikatora biološkog odgovora u fiziološkim i patološkim stanjima (RS-145006)

DOI: 10.1016/j.jorganchem.2009.08.013

ISSN: 0022-328X

WoS: 000271099300015

Scopus: 2-s2.0-70349999659
[ Google Scholar ]
60
58
URI
http://cer.ihtm.bg.ac.rs/handle/123456789/619
Collections
  • Radovi istraživača / Researchers' publications
Institution
IHTM

DSpace software copyright © 2002-2015  DuraSpace
About CeR – Central Repository | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceInstitutionsAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About CeR – Central Repository | Send Feedback

OpenAIRERCUB