Hydride reduction of B-norcholestane 5α,6α-epoxide
Hidridna redukcija B-norholestan 5α,6α-epoksida
Apstrakt
B-Norcholestane epoxide 2 is reduced with lithium aluminium hydride to give either the 3β,6α-diol 3 or the corresponding 3β,5α-diol 4, depending on the quality of the reducing reagent employed. Aplausible mechanistic explanation of the obtained results is suggested.
Redukcijom B-norholestan-epoksida 2 pomoću litijum-aluminijum-hidrida dobijeni su odgovarajući 3β,6α-diol 3 ili 3β,5α-diol 4, u zavisnosti od kvaliteta upotrebljenog redukcionog reagensa. Predloženo je verovatno mehanističko tumačenje dobijenih rezultata.
Ključne reči:
5α,6α-epoxy-B-norcholestan-3β-yl acetate / 5α-hydroxy-B-norcholestan-3β-yl acetate / 6α-hydroxy-B-nor-5β-cholestan-3β-yl acetate / lithium aluminium hydride / lithium triethylborohydrideIzvor:
Journal of the Serbian Chemical Society, 2002, 67, 2, 69-75Izdavač:
- Serbian Chemical Society
Finansiranje / projekti:
- Project MESTD
DOI: 10.2298/JSC0202069B
ISSN: 0352-5139
WoS: 000173995100001
Scopus: 2-s2.0-0036003604
Institucija/grupa
IHTMTY - JOUR AU - Bjelaković, Mira AU - Pavlović, Vladimir D. AU - Lorenc, Ljubinka PY - 2002 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/60 AB - B-Norcholestane epoxide 2 is reduced with lithium aluminium hydride to give either the 3β,6α-diol 3 or the corresponding 3β,5α-diol 4, depending on the quality of the reducing reagent employed. Aplausible mechanistic explanation of the obtained results is suggested. AB - Redukcijom B-norholestan-epoksida 2 pomoću litijum-aluminijum-hidrida dobijeni su odgovarajući 3β,6α-diol 3 ili 3β,5α-diol 4, u zavisnosti od kvaliteta upotrebljenog redukcionog reagensa. Predloženo je verovatno mehanističko tumačenje dobijenih rezultata. PB - Serbian Chemical Society T2 - Journal of the Serbian Chemical Society T1 - Hydride reduction of B-norcholestane 5α,6α-epoxide T1 - Hidridna redukcija B-norholestan 5α,6α-epoksida VL - 67 IS - 2 SP - 69 EP - 75 DO - 10.2298/JSC0202069B ER -
@article{ author = "Bjelaković, Mira and Pavlović, Vladimir D. and Lorenc, Ljubinka", year = "2002", abstract = "B-Norcholestane epoxide 2 is reduced with lithium aluminium hydride to give either the 3β,6α-diol 3 or the corresponding 3β,5α-diol 4, depending on the quality of the reducing reagent employed. Aplausible mechanistic explanation of the obtained results is suggested., Redukcijom B-norholestan-epoksida 2 pomoću litijum-aluminijum-hidrida dobijeni su odgovarajući 3β,6α-diol 3 ili 3β,5α-diol 4, u zavisnosti od kvaliteta upotrebljenog redukcionog reagensa. Predloženo je verovatno mehanističko tumačenje dobijenih rezultata.", publisher = "Serbian Chemical Society", journal = "Journal of the Serbian Chemical Society", title = "Hydride reduction of B-norcholestane 5α,6α-epoxide, Hidridna redukcija B-norholestan 5α,6α-epoksida", volume = "67", number = "2", pages = "69-75", doi = "10.2298/JSC0202069B" }
Bjelaković, M., Pavlović, V. D.,& Lorenc, L.. (2002). Hydride reduction of B-norcholestane 5α,6α-epoxide. in Journal of the Serbian Chemical Society Serbian Chemical Society., 67(2), 69-75. https://doi.org/10.2298/JSC0202069B
Bjelaković M, Pavlović VD, Lorenc L. Hydride reduction of B-norcholestane 5α,6α-epoxide. in Journal of the Serbian Chemical Society. 2002;67(2):69-75. doi:10.2298/JSC0202069B .
Bjelaković, Mira, Pavlović, Vladimir D., Lorenc, Ljubinka, "Hydride reduction of B-norcholestane 5α,6α-epoxide" in Journal of the Serbian Chemical Society, 67, no. 2 (2002):69-75, https://doi.org/10.2298/JSC0202069B . .