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dc.creatorŽivković, Jelena
dc.creatorZeković, Z.
dc.creatorMujić, I.
dc.creatorGođevac, Dejan
dc.creatorMojović, Miloš
dc.creatorMujić, A.
dc.creatorSpasojević, I.
dc.date.accessioned2019-01-30T17:21:50Z
dc.date.available2019-01-30T17:21:50Z
dc.date.issued2009
dc.identifier.issn1557-1858
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/609
dc.description.abstractElectron paramagnetic resonance (EPR) spin-trapping and spin-probing techniques were applied to determine antioxidant activity of extracts of catkin, leaves, and spiny burs of Castanea sativa against physiologically relevant reactive species-superoxide and hydroxyl radical generated in simple chemical systems and hydrogen peroxide applied on erythrocytes. Efflux of K + was used as a marker of membrane integrity. Chemical composition of extracts was analyzed using HPLC/DAD and LC/MS. Extracts showed high antioxidative capacity against superoxide but lower activity against hydroxyl radical. They protected fluidity and integrity of membranes of erythrocytes exposed to hydrogen peroxide. Levels of derivatives of ellagitannins showed positive correlation with the antioxidative activity of extracts. Therefore, ellagitannins from chestnut extracts could represent easily accessible natural antioxidants and beneficial component of human diet in pathophysiological conditions related to oxidative stress. In conclusion, EPR spectroscopy represents a valuable tool for evaluation of antioxidant activity in both hydrophilic and lipophilic media.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/143016/RS//
dc.rightsrestrictedAccess
dc.sourceFood Biophysics
dc.subjectAntioxidanten
dc.subjectCastanea sativaen
dc.subjectEllagitanninsen
dc.subjectEPRen
dc.subjectOxidative stressen
dc.titleEPR spin-trapping and spin-probing spectroscopy in assessing antioxidant properties: Example on extracts of catkin, leaves, and spiny burs of castanea sativaen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСпасојевић, И.; Гођевац, Дејан; Мојовић, М.; Мујић, И.; Мујић, A.; Живковић, Ј.; Зековић, З.;
dc.citation.volume4
dc.citation.issue2
dc.citation.spage126
dc.citation.epage133
dc.citation.other4(2): 126-133
dc.citation.rankM22
dc.identifier.doi10.1007/s11483-009-9109-8
dc.identifier.rcubConv_4200
dc.identifier.scopus2-s2.0-67349213556
dc.identifier.wos000266007700008
dc.type.versionpublishedVersion


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